Lista de obras - Josephine H Cox - Dominio Público Uruguay

A DNA-based candidate HIV vaccine delivered via in vivo electroporation induces CD4 responses toward the α4β7-binding V2 loop of HIV gp120 in healthy volunteers

artículo científico publicado en 2012

A New Multi-clade DNA Prime/Recombinant MVA Boost Vaccine Induces Broad and High Levels of HIV-1-specific CD8+ T-cell and Humoral Responses in Mice

article

A Phase 1 Study of 4 Live, Recombinant Human Cytomegalovirus Towne/Toledo Chimera Vaccines in Cytomegalovirus-Seronegative Men

artículo científico publicado en 2016

A Phase 1 study to evaluate the safety and immunogenicity of a recombinant HIV type 1 subtype C-modified vaccinia Ankara virus vaccine candidate in Indian volunteers

artículo científico publicado en 2009

A Phase I Double Blind, Placebo-Controlled, Randomized Study of the Safety and Immunogenicity of Electroporated HIV DNA with or without Interleukin 12 in Prime-Boost Combinations with an Ad35 HIV Vaccine in Healthy HIV-Seronegative African Adults

artículo científico publicado en 2015

A Phase I Double Blind, Placebo-Controlled, Randomized Study of the Safety and Immunogenicity of an Adjuvanted HIV-1 Gag-Pol-Nef Fusion Protein and Adenovirus 35 Gag-RT-Int-Nef Vaccine in Healthy HIV-Uninfected African Adults

artículo científico publicado en 2015

A double-blind randomized phase I clinical trial targeting ALVAC-HIV vaccine to human dendritic cells

artículo científico publicado en 2011

A high viral burden predicts the loss of CD8 T-cell responses specific for subdominant gag epitopes during chronic human immunodeficiency virus infection

artículo científico publicado en 2007

A panel of MHC class I restricted viral peptides for use as a quality control for vaccine trial ELISPOT assays

artículo científico publicado en 2002

A phase 1/2 study of a multiclade HIV-1 DNA plasmid prime and recombinant adenovirus serotype 5 boost vaccine in HIV-Uninfected East Africans (RV 172).

artículo científico publicado en 2010

A phase 2 study to evaluate the safety and immunogenicity of a recombinant HIV type 1 vaccine based on adeno-associated virus

artículo científico publicado en 2010

A phase I double blind, placebo-controlled, randomized study of a multigenic HIV-1 adenovirus subtype 35 vector vaccine in healthy uninfected adults

artículo científico publicado en 2012

Adeno-associated virus vectored immunoprophylaxis to prevent HIV in healthy adults: a phase 1 randomised controlled trial

article

Adenovirus-based HIV-1 vaccine candidates tested in efficacy trials elicit CD8+ T cells with limited breadth of HIV-1 inhibition

artículo científico publicado en 2016

An influenza vaccine pill-can we swallow it?

artículo científico publicado en 2015

Antibody-dependent cell-mediated cytotoxic responses in participants enrolled in a phase I/II ALVAC-HIV/AIDSVAX B/E prime-boost HIV-1 vaccine trial in Thailand

artículo científico publicado en 2005

Antigen-specific T-cell-mediated immunity after HIV-1 infection: implications for vaccine control of HIV development

artículo científico publicado en 2006

Assessment of Anti-HIV-1 Antibodies in Oral and Nasal Compartments of Volunteers From 3 Different Populations

artículo científico publicado en 2016

Assessment of the Safety and Immunogenicity of 2 Novel Vaccine Platforms for HIV-1 Prevention: A Randomized Trial

artículo científico publicado en 2016

Broad HIV epitope specificity and viral inhibition induced by multigenic HIV-1 adenovirus subtype 35 vector vaccine in healthy uninfected adults

artículo científico publicado en 2014

Broad HIV-1 inhibition in vitro by vaccine-elicited CD8(+) T cells in African adults

artículo científico publicado en 2016

Broad immunogenicity of a multigene, multiclade HIV-1 DNA vaccine boosted with heterologous HIV-1 recombinant modified vaccinia virus Ankara

artículo científico publicado en 2008

CD8 T-cell recognition of multiple epitopes within specific Gag regions is associated with maintenance of a low steady-state viremia in human immunodeficiency virus type 1-seropositive patients

artículo científico publicado en 2006

CTL epitope distribution patterns in the Gag and Nef proteins of HIV-1 from subtype A infected subjects in Kenya: use of multiple peptide sets increases the detectable breadth of the CTL response.

artículo científico publicado en 2006

Circulating and unique recombinant forms of HIV type 1 containing subsubtype A2.

artículo científico publicado en 2006

Comprehensive screening for human immunodeficiency virus type 1 subtype-specific CD8 cytotoxic T lymphocytes and definition of degenerate epitopes restricted by HLA-A0207 and -C(W)0304 alleles

artículo científico publicado en 2002

Concordant proficiency in measurement of T-cell immunity in human immunodeficiency virus vaccine clinical trials by peripheral blood mononuclear cell and enzyme-linked immunospot assays in laboratories from three continents

artículo científico publicado en 2008

Cryopreservation-related loss of antigen-specific IFNγ producing CD4+ T-cells can skew immunogenicity data in vaccine trials: Lessons from a malaria vaccine trial substudy

artículo científico publicado en 2017

Design and evaluation of multi-gene, multi-clade HIV-1 MVA vaccines

artículo científico publicado en 2009

Detection of high frequencies of HIV-1 cross-subtype reactive CD8 T lymphocytes in the peripheral blood of HIV-1-infected Kenyans

artículo científico publicado en 2003

Development of a luciferase based viral inhibition assay to evaluate vaccine induced CD8 T-cell responses

artículo científico publicado en 2013

Effect of a Chikungunya Virus-Like Particle Vaccine on Safety and Tolerability Outcomes: A Randomized Clinical Trial

scientific article published on 01 April 2020

Endpoint Assays in HIV-1 Vaccine Trials: Functioning in a Good Laboratory Practices Environment

article

Equivalence of ELISpot assays demonstrated between major HIV network laboratories

artículo científico publicado en 2010

Establishment and maintenance of a PBMC repository for functional cellular studies in support of clinical vaccine trials

artículo científico publicado en 2014

Evaluation and recommendations on good clinical laboratory practice guidelines for phase I-III clinical trials

artículo científico publicado en 2009

Evaluation of Natural Killer Cell Activity

artículo científico publicado el 1 de enero de 1999

Evaluation of natural killer cell activity

artículo científico publicado en 2000

First-in-Human Evaluation of the Safety and Immunogenicity of an Intranasally Administered Replication-Competent Sendai Virus-Vectored HIV Type 1 Gag Vaccine: Induction of Potent T-Cell or Antibody Responses in Prime-Boost Regimens

artículo científico publicado en 2016

HIV-1 MN Env 15-mer peptides better detect HIV-1 specific CD8 T cell responses compared with consensus subtypes B and M group 15-mer peptides

artículo científico publicado en 2005

HIV-1-Specific Antibody-Dependent Cellular Cytotoxicity (ADCC).

artículo científico publicado en 1999

HIV-1-Specific Cytotoxic T-Cell Assays

artículo científico publicado el 1 de enero de 1999

HLA-A and -B allele expression and ability to develop anti-Gag cross-clade responses in subtype C HIV-1-infected Ethiopians

artículo científico publicado en 2004

Heterologous prime-boost regimens using rAd35 and rMVA vectors elicit stronger cellular immune responses to HIV proteins than homologous regimens

artículo científico publicado en 2012

Identification of a novel HIV type 1 CRF01_AE cytotoxic T lymphocyte (CTL) epitope restricted by an HLA-Cw0602 allele and a novel HLA-A0206/peptide restriction

artículo científico publicado en 2006

Immune activation alters cellular and humoral responses to yellow fever 17D vaccine

artículo científico publicado en 2014

Immune reconstitution following autologous transfers of CD3/CD28 stimulated CD4(+) T cells to HIV-infected persons

artículo científico publicado en 2004

Immunodominance and Cross-Reactivity of B5703-Restricted CD8 T Lymphocytes from HIV Type 1 Subtype C-Infected Ethiopians

article

In a mixed subtype epidemic, the HIV-1 Gag-specific T-cell response is biased towards the infecting subtype

artículo científico publicado en 2007

In vivo electroporation enhances the immunogenicity of an HIV-1 DNA vaccine candidate in healthy volunteers

artículo científico publicado en 2011

Inclusion of a CRF01_AE HIV envelope protein boost with a DNA/MVA prime-boost vaccine: Impact on humoral and cellular immunogenicity and viral load reduction after SHIV-E challenge

artículo científico publicado en 2012

Induction of HIV-specific functional immune responses by a multiclade HIV-1 DNA vaccine candidate in healthy Ugandans

artículo científico publicado en 2007

Intra- and inter-clade cross-reactivity by HIV-1 Gag specific T-cells reveals exclusive and commonly targeted regions: implications for current vaccine trials

artículo científico publicado en 2011

Long-term follow-up of study participants from prophylactic HIV vaccine clinical trials in Africa

artículo científico publicado en 2014

Longitudinal study of humoral immune responses in HIV type 1 subtype CRF01_AE (E)-infected Thai patients with different rates of disease progression

artículo científico publicado en 2003

Lost in translation: implications of HIV-1 codon usage for immune escape and drug resistance.

artículo científico publicado en 2004

Lymphocyte traffic in pregnant or oestrogen stimulated rats

artículo científico publicado en 1984

Magnitude, breadth, and functional profile of T-cell responses during human immunodeficiency virus primary infection with B and BF viral variants

artículo científico publicado en 2008

Measurement of cytokine release at the single cell level using the ELISPOT assay

artículo científico publicado en 2006

Multiplexed FluoroSpot for the Analysis of Dengue Virus- and Zika Virus-Specific and Cross-Reactive Memory B Cells

article

Orientation of epitopes influences the immunogenicity of synthetic peptide dimers

scientific article published on 01 December 1988

Peptide impurities in commercial synthetic peptides and their implications for vaccine trial assessment

artículo científico publicado en 2007

Phase 1 safety and immunogenicity evaluation of ADMVA, a multigenic, modified vaccinia Ankara-HIV-1 B'/C candidate vaccine

artículo científico publicado en 2010

Phase 1 safety and immunogenicity evaluation of ADVAX, a multigenic, DNA-based clade C/B' HIV-1 candidate vaccine

artículo científico publicado en 2010

Phase I safety and immunogenicity evaluation of MVA-CMDR, a multigenic, recombinant modified vaccinia Ankara-HIV-1 vaccine candidate

artículo científico publicado en 2010

Phase I study of safety and immunogenicity of an Escherichia coli-derived recombinant protective antigen (rPA) vaccine to prevent anthrax in adults

artículo científico publicado en 2010

Preparation of clinical-grade recombinant canarypox-human immunodeficiency virus vaccine-loaded human dendritic cells

artículo científico publicado en 2002

Prior Dengue virus exposure shapes T cell immunity to Zika virus in humans

artículo científico publicado en 2017

Quality monitoring of HIV-1-infected and uninfected peripheral blood mononuclear cell samples in a resource-limited setting

artículo científico publicado en 2010

Recombinant Modified Vaccinia Ankara (MVA) effectively boosts DNA-primed HIV-specific immune responses in humans despite pre-existing vaccinia immunity

artículo científico publicado en 2009

Results of an ELISPOT proficiency panel conducted in 11 laboratories participating in international human immunodeficiency virus type 1 vaccine trials

artículo científico publicado en 2005

Retention of adenovirus E19 glycoprotein in the endoplasmic reticulum is essential to its ability to block antigen presentation ⬇️

artículo científico publicado el 1 de diciembre de 1991

Safety and Immunogenicity of a Randomized Phase 1 Prime-Boost Trial With ALVAC-HIV (vCP205) and Oligomeric Glycoprotein 160 From HIV-1 Strains MN and LAI-2 Adjuvanted in Alum or Polyphosphazene

artículo científico publicado en 2016

Safety and immunogenicity of DNA and MVA HIV-1 subtype C vaccine prime-boost regimens: a phase I randomised Trial in HIV-uninfected Indian volunteers

artículo científico publicado en 2013

Safety and immunogenicity of DNA prime and modified vaccinia ankara virus-HIV subtype C vaccine boost in healthy adults.

artículo científico publicado en 2013

Safety and immunogenicity study of Multiclade HIV-1 adenoviral vector vaccine alone or as boost following a multiclade HIV-1 DNA vaccine in Africa

artículo científico publicado en 2010

Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials

artículo científico publicado en 2017

Standardization and validation issues of the ELISPOT assay

artículo científico publicado en 2005

Standardization of cytokine flow cytometry assays

artículo científico publicado en 2005

The 65kDa antigen of mycobacteria-a common bacterial protein?

artículo científico publicado en 1987

The External Quality Assurance Oversight Laboratory (EQAPOL) proficiency program for IFN-gamma enzyme-linked immunospot (IFN-γ ELISpot) assay

artículo científico publicado en 2014

The effects of cyclosporin on lymphocyte activation in a systemic graft-vs.-host reaction

scientific article published on 01 October 1985

The kinetics and specificity of lymphocyte infiltration of cardiac allografts in unmodified and cyclosporin-treated rats ⬇️

artículo científico publicado el 1 de julio de 1984

The migration of lymphocytes across specialized vascular endothelium. IV. Prednisolone acts at several points on the recirculation pathways of lymphocytes

scientific article published on 01 January 1982

Vaccine-elicited human T cells recognizing conserved protein regions inhibit HIV-1.

scientific article published on 31 October 2013

Varicella zoster virus--specific immune response after treatment with sodium stibogluconate for cutaneous leishmaniasis

artículo científico publicado en 2008

Lista de obras de Josephine H Cox

A DNA-based candidate HIV vaccine delivered via in vivo electroporation induces CD4 responses toward the α4β7-binding V2 loop of HIV gp120 in healthy volunteers

A New Multi-clade DNA Prime/Recombinant MVA Boost Vaccine Induces Broad and High Levels of HIV-1-specific CD8+ T-cell and Humoral Responses in Mice

A Phase 1 Study of 4 Live, Recombinant Human Cytomegalovirus Towne/Toledo Chimera Vaccines in Cytomegalovirus-Seronegative Men

A Phase 1 study to evaluate the safety and immunogenicity of a recombinant HIV type 1 subtype C-modified vaccinia Ankara virus vaccine candidate in Indian volunteers

A Phase I Double Blind, Placebo-Controlled, Randomized Study of the Safety and Immunogenicity of Electroporated HIV DNA with or without Interleukin 12 in Prime-Boost Combinations with an Ad35 HIV Vaccine in Healthy HIV-Seronegative African Adults

A Phase I Double Blind, Placebo-Controlled, Randomized Study of the Safety and Immunogenicity of an Adjuvanted HIV-1 Gag-Pol-Nef Fusion Protein and Adenovirus 35 Gag-RT-Int-Nef Vaccine in Healthy HIV-Uninfected African Adults

A double-blind randomized phase I clinical trial targeting ALVAC-HIV vaccine to human dendritic cells

A high viral burden predicts the loss of CD8 T-cell responses specific for subdominant gag epitopes during chronic human immunodeficiency virus infection

A panel of MHC class I restricted viral peptides for use as a quality control for vaccine trial ELISPOT assays

A phase 1/2 study of a multiclade HIV-1 DNA plasmid prime and recombinant adenovirus serotype 5 boost vaccine in HIV-Uninfected East Africans (RV 172).

A phase 2 study to evaluate the safety and immunogenicity of a recombinant HIV type 1 vaccine based on adeno-associated virus

A phase I double blind, placebo-controlled, randomized study of a multigenic HIV-1 adenovirus subtype 35 vector vaccine in healthy uninfected adults

Adeno-associated virus vectored immunoprophylaxis to prevent HIV in healthy adults: a phase 1 randomised controlled trial

Adenovirus-based HIV-1 vaccine candidates tested in efficacy trials elicit CD8+ T cells with limited breadth of HIV-1 inhibition

An influenza vaccine pill-can we swallow it?

Antibody-dependent cell-mediated cytotoxic responses in participants enrolled in a phase I/II ALVAC-HIV/AIDSVAX B/E prime-boost HIV-1 vaccine trial in Thailand

Antigen-specific T-cell-mediated immunity after HIV-1 infection: implications for vaccine control of HIV development

Assessment of Anti-HIV-1 Antibodies in Oral and Nasal Compartments of Volunteers From 3 Different Populations

Assessment of the Safety and Immunogenicity of 2 Novel Vaccine Platforms for HIV-1 Prevention: A Randomized Trial

Broad HIV epitope specificity and viral inhibition induced by multigenic HIV-1 adenovirus subtype 35 vector vaccine in healthy uninfected adults

Broad HIV-1 inhibition in vitro by vaccine-elicited CD8(+) T cells in African adults

Broad immunogenicity of a multigene, multiclade HIV-1 DNA vaccine boosted with heterologous HIV-1 recombinant modified vaccinia virus Ankara

CD8 T-cell recognition of multiple epitopes within specific Gag regions is associated with maintenance of a low steady-state viremia in human immunodeficiency virus type 1-seropositive patients

CTL epitope distribution patterns in the Gag and Nef proteins of HIV-1 from subtype A infected subjects in Kenya: use of multiple peptide sets increases the detectable breadth of the CTL response.

Circulating and unique recombinant forms of HIV type 1 containing subsubtype A2.

Comprehensive screening for human immunodeficiency virus type 1 subtype-specific CD8 cytotoxic T lymphocytes and definition of degenerate epitopes restricted by HLA-A0207 and -C(W)0304 alleles

Concordant proficiency in measurement of T-cell immunity in human immunodeficiency virus vaccine clinical trials by peripheral blood mononuclear cell and enzyme-linked immunospot assays in laboratories from three continents

Cryopreservation-related loss of antigen-specific IFNγ producing CD4+ T-cells can skew immunogenicity data in vaccine trials: Lessons from a malaria vaccine trial substudy

Design and evaluation of multi-gene, multi-clade HIV-1 MVA vaccines

Detection of high frequencies of HIV-1 cross-subtype reactive CD8 T lymphocytes in the peripheral blood of HIV-1-infected Kenyans

Development of a luciferase based viral inhibition assay to evaluate vaccine induced CD8 T-cell responses

Effect of a Chikungunya Virus-Like Particle Vaccine on Safety and Tolerability Outcomes: A Randomized Clinical Trial

Endpoint Assays in HIV-1 Vaccine Trials: Functioning in a Good Laboratory Practices Environment

Equivalence of ELISpot assays demonstrated between major HIV network laboratories

Establishment and maintenance of a PBMC repository for functional cellular studies in support of clinical vaccine trials

Evaluation and recommendations on good clinical laboratory practice guidelines for phase I-III clinical trials

Evaluation of Natural Killer Cell Activity

Evaluation of natural killer cell activity

First-in-Human Evaluation of the Safety and Immunogenicity of an Intranasally Administered Replication-Competent Sendai Virus-Vectored HIV Type 1 Gag Vaccine: Induction of Potent T-Cell or Antibody Responses in Prime-Boost Regimens

HIV-1 MN Env 15-mer peptides better detect HIV-1 specific CD8 T cell responses compared with consensus subtypes B and M group 15-mer peptides

HIV-1-Specific Antibody-Dependent Cellular Cytotoxicity (ADCC).

HIV-1-Specific Cytotoxic T-Cell Assays

HLA-A and -B allele expression and ability to develop anti-Gag cross-clade responses in subtype C HIV-1-infected Ethiopians

Heterologous prime-boost regimens using rAd35 and rMVA vectors elicit stronger cellular immune responses to HIV proteins than homologous regimens

Identification of a novel HIV type 1 CRF01_AE cytotoxic T lymphocyte (CTL) epitope restricted by an HLA-Cw0602 allele and a novel HLA-A0206/peptide restriction

Immune activation alters cellular and humoral responses to yellow fever 17D vaccine

Immune reconstitution following autologous transfers of CD3/CD28 stimulated CD4(+) T cells to HIV-infected persons

Immunodominance and Cross-Reactivity of B5703-Restricted CD8 T Lymphocytes from HIV Type 1 Subtype C-Infected Ethiopians

In a mixed subtype epidemic, the HIV-1 Gag-specific T-cell response is biased towards the infecting subtype

In vivo electroporation enhances the immunogenicity of an HIV-1 DNA vaccine candidate in healthy volunteers

Inclusion of a CRF01_AE HIV envelope protein boost with a DNA/MVA prime-boost vaccine: Impact on humoral and cellular immunogenicity and viral load reduction after SHIV-E challenge

Induction of HIV-specific functional immune responses by a multiclade HIV-1 DNA vaccine candidate in healthy Ugandans

Intra- and inter-clade cross-reactivity by HIV-1 Gag specific T-cells reveals exclusive and commonly targeted regions: implications for current vaccine trials

Long-term follow-up of study participants from prophylactic HIV vaccine clinical trials in Africa

Longitudinal study of humoral immune responses in HIV type 1 subtype CRF01_AE (E)-infected Thai patients with different rates of disease progression

Lost in translation: implications of HIV-1 codon usage for immune escape and drug resistance.

Lymphocyte traffic in pregnant or oestrogen stimulated rats

Magnitude, breadth, and functional profile of T-cell responses during human immunodeficiency virus primary infection with B and BF viral variants

Measurement of cytokine release at the single cell level using the ELISPOT assay

Multiplexed FluoroSpot for the Analysis of Dengue Virus- and Zika Virus-Specific and Cross-Reactive Memory B Cells

Orientation of epitopes influences the immunogenicity of synthetic peptide dimers

Peptide impurities in commercial synthetic peptides and their implications for vaccine trial assessment

Phase 1 safety and immunogenicity evaluation of ADMVA, a multigenic, modified vaccinia Ankara-HIV-1 B'/C candidate vaccine

Phase 1 safety and immunogenicity evaluation of ADVAX, a multigenic, DNA-based clade C/B' HIV-1 candidate vaccine

Phase I safety and immunogenicity evaluation of MVA-CMDR, a multigenic, recombinant modified vaccinia Ankara-HIV-1 vaccine candidate

Phase I study of safety and immunogenicity of an Escherichia coli-derived recombinant protective antigen (rPA) vaccine to prevent anthrax in adults

Preparation of clinical-grade recombinant canarypox-human immunodeficiency virus vaccine-loaded human dendritic cells

Prior Dengue virus exposure shapes T cell immunity to Zika virus in humans

Quality monitoring of HIV-1-infected and uninfected peripheral blood mononuclear cell samples in a resource-limited setting

Recombinant Modified Vaccinia Ankara (MVA) effectively boosts DNA-primed HIV-specific immune responses in humans despite pre-existing vaccinia immunity

Results of an ELISPOT proficiency panel conducted in 11 laboratories participating in international human immunodeficiency virus type 1 vaccine trials

Retention of adenovirus E19 glycoprotein in the endoplasmic reticulum is essential to its ability to block antigen presentation ⬇️

Safety and Immunogenicity of a Randomized Phase 1 Prime-Boost Trial With ALVAC-HIV (vCP205) and Oligomeric Glycoprotein 160 From HIV-1 Strains MN and LAI-2 Adjuvanted in Alum or Polyphosphazene

Safety and immunogenicity of DNA and MVA HIV-1 subtype C vaccine prime-boost regimens: a phase I randomised Trial in HIV-uninfected Indian volunteers

Safety and immunogenicity of DNA prime and modified vaccinia ankara virus-HIV subtype C vaccine boost in healthy adults.

Safety and immunogenicity study of Multiclade HIV-1 adenoviral vector vaccine alone or as boost following a multiclade HIV-1 DNA vaccine in Africa

Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials

Standardization and validation issues of the ELISPOT assay

Standardization of cytokine flow cytometry assays