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Lista de obras de Michael Detmar

A Human mAb Specific to Oncofetal Fibronectin Selectively Targets Chronic Skin Inflammation In Vivo

A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules

artículo científico publicado en 2015

A novel role for microphthalmia-associated transcription factor-regulated pigment epithelium-derived factor during melanoma progression

artículo científico publicado en 2014

A role for all-trans-retinoic acid in the early steps of lymphatic vasculature development ⬇️

artículo científico publicado el 23 de noviembre de 2010

A transgenic Prox1-Cre-tdTomato reporter mouse for lymphatic vessel research

artículo científico publicado en 2015

Activation of the VEGFC/VEGFR3 Pathway Induces Tumor Immune Escape in Colorectal Cancer

artículo científico publicado en 2019

Activation of the epidermal growth factor receptor promotes lymphangiogenesis in the skin ⬇️

artículo científico publicado el 4 de mayo de 2013

Activation of the tie2 receptor by angiopoietin-1 enhances tumor vessel maturation and impairs squamous cell carcinoma growth

artículo científico publicado en 2002

Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis

artículo científico publicado en 2008

Alternative transcription of a shorter, non-anti-angiogenic thrombospondin-2 variant in cancer-associated blood vessels.

artículo científico publicado en 2018

An N-terminal 80 kDa recombinant fragment of human thrombospondin-2 inhibits vascular endothelial growth factor induced endothelial cell migration in vitro and tumor growth and angiogenesis in vivo

artículo científico publicado en 2003

An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype

scientific journal article

An exquisite cross-control mechanism among endothelial cell fate regulators directs the plasticity and heterogeneity of lymphatic endothelial cells

artículo científico publicado en 2010

An important role of blood and lymphatic vessels in inflammation and allergy

artículo científico publicado en 2013

An important role of cutaneous lymphatic vessels in coordinating and promoting anagen hair follicle growth

scientific article published on 25 July 2019

An important role of lymphatic vessel activation in limiting acute inflammation

artículo científico publicado en 2011

An important role of podoplanin in hair follicle growth

artículo científico publicado en 2019

An important role of the SDF-1/CXCR4 axis in chronic skin inflammation

artículo científico publicado en 2014

An in vivo chemical library screen in Xenopus tadpoles reveals novel pathways involved in angiogenesis and lymphangiogenesis

artículo científico publicado en 2009

An integrated expression atlas of miRNAs and their promoters in human and mouse.

artículo científico publicado en 2017

Analysis of a novel highly metastatic melanoma cell line identifies osteopontin as a new lymphangiogenic factor ⬇️

artículo científico publicado el 6 de julio de 2012

Angiogenesis and lymphangiogenesis of skin cancers

artículo científico publicado en 2004

Angiogenesis, lymphangiogenesis, and melanoma metastasis

artículo científico publicado en 2003

Antibody-mediated delivery of VEGF-C potently reduces chronic skin inflammation

article published in 2018

Antibody-mediated delivery of interleukin 4 to the neo-vasculature reduces chronic skin inflammation

artículo científico publicado en 2014

Blockade of VEGF Receptor-3 Aggravates Inflammatory Bowel Disease and Lymphatic Vessel Enlargement ⬇️

artículo científico publicado el 1 de agosto de 2013

Blockade of VEGF-C and VEGF-D modulates adipose tissue inflammation and improves metabolic parameters under high-fat diet

artículo científico publicado en 2014

Chapter 1. Inflammation, angiogenesis, and lymphangiogenesis

artículo científico publicado en 2008

Chronic high-fat diet impairs collecting lymphatic vessel function in mice

artículo científico publicado en 2014

Connexin 43 expression predicts poor progression-free survival in patients with non-muscle invasive urothelial bladder cancer

artículo científico publicado en 2015

Coxsackie- and adenovirus receptor (CAR) is expressed in lymphatic vessels in human skin and affects lymphatic endothelial cell function in vitro

artículo científico publicado en 2008

De novo design and optimization of Aurora A kinase inhibitors

DeepCAGE Transcriptomics Reveal an Important Role of the Transcription Factor MAFB in the Lymphatic Endothelium

artículo científico publicado en 2015

DeepCAGE transcriptomics identify HOXD10 as a transcription factor regulating lymphatic endothelial responses to VEGF-C.

artículo científico publicado en 2016

Development of the lymphatic vascular system: a mystery unravels

artículo científico publicado en 2004

Differential effects of anaesthesia on the contractility of lymphatic vessels in vivo

scientific article published on 20 March 2019

Differential effects of anaesthesia on the contractility of lymphatic vessels in vivo: authors' reply

artículo científico publicado en 2020

Differential effects of photoaging vs intrinsic aging on the vascularization of human skin

artículo científico publicado en 2002

Distinct transcriptional responses of lymphatic endothelial cells to VEGFR-3 and VEGFR-2 stimulation.

artículo científico

Down-regulation of microRNA-34a* in rheumatoid arthritis synovial fibroblasts promotes apoptosis resistance

artículo científico publicado en 2011

Ectodomain Shedding of Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE-1) Is Induced by Vascular Endothelial Growth Factor A (VEGF-A)

artículo científico publicado en 2016

Effects of rIFN Alpha, Beta, and Gamma on the Morphology, Proliferation, and Cell Surface Antigen Expression of Human Dermal Microvascular Endothelial Cells In Vitro

artículo científico publicado en 1990

Endocan Is Upregulated on Tumor Vessels in Invasive Bladder Cancer Where It Mediates VEGF-A–Induced Angiogenesis ⬇️

artículo científico publicado el 14 de diciembre de 2012

Endothelialized networks with a vascular geometry in microfabricated poly(dimethyl siloxane).

artículo científico publicado en 2004

Epigenetic regulation of the lineage specificity of primary human dermal lymphatic and blood vascular endothelial cells

scientific article published on 12 September 2020

Evidence for vascular endothelial growth factor (VEGF) as a modifier gene in psoriasis

artículo científico publicado en 2004

Expression of the type-1 repeats of thrombospondin-1 inhibits tumor growth through activation of transforming growth factor-beta

artículo científico publicado en 2004

FANTOM5 CAGE profiles of human and mouse samples

artículo científico

Fingerprinting breast cancer vs. normal mammary cells by mass spectrometric analysis of volatiles

scientific article published on 06 June 2014

G-CSF regulates macrophage phenotype and associates with poor overall survival in human triple-negative breast cancer

artículo científico publicado en 2015

Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions

artículo científico publicado en 2009

Genetic ablation of SOX18 function suppresses tumor lymphangiogenesis and metastasis of melanoma in mice

artículo científico publicado en 2012

Growth hormone promotes lymphangiogenesis

artículo científico publicado en 2008

Hepatocyte growth factor promotes lymphatic vessel formation and function

artículo científico publicado en 2005

Identification of UV-protective activators of nuclear factor erythroid-derived 2-related factor 2 (Nrf2) by combining a chemical library screen with computer-based virtual screening

artículo científico publicado en 2012

Identification of the surface-accessible, lineage-specific vascular proteome by two-dimensional peptide mapping

article by Christoph Roesli et al published June 2008 in FASEB Journal

In Vivo Imaging of Lymph Node Lymphangiogenesis by Immuno-Positron Emission Tomography ⬇️

artículo científico publicado el 1 de enero de 2013

In vivo imaging of inflammation- and tumor-induced lymph node lymphangiogenesis by immuno-positron emission tomography

artículo científico publicado en 2010

Increased and prolonged inflammation and angiogenesis in delayed-type hypersensitivity reactions elicited in the skin of thrombospondin-2--deficient mice

artículo científico publicado en 2002

Induced lymphatic sinus hyperplasia in sentinel lymph nodes by VEGF-C as the earliest premetastatic indicator ⬇️

artículo científico publicado el 16 de octubre de 2012

Induction of cutaneous delayed-type hypersensitivity reactions in VEGF-A transgenic mice results in chronic skin inflammation associated with persistent lymphatic hyperplasia

artículo científico publicado en 2004

Induction of lymphatic endothelial cell differentiation in embryoid bodies

artículo científico publicado en 2005

Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis

article by Mihaela Skobe et al published February 2001 in Nature Medicine

Infantile hemangiomas are arrested in an early developmental vascular differentiation state

artículo científico publicado en 2004

Inflammation and Lymphatic Function

Inflammation-Induced Lymph Node Lymphangiogenesis Is Reversible ⬇️

artículo científico publicado el 23 de diciembre de 2011

Inhibition of chronic and acute skin inflammation by treatment with a vascular endothelial growth factor receptor tyrosine kinase inhibitor

artículo científico publicado en 2008

Itch suppression in mice and dogs by modulation of spinal α2 and α3GABA receptors

artículo científico publicado en 2018

Keratinocyte-Expressed Podoplanin is Dispensable for Multi-Step Skin Carcinogenesis

artículo científico publicado en 2020

LETR1 is a lymphatic endothelial-specific lncRNA governing cell proliferation and migration through KLF4 and SEMA3C

artículo científico publicado en 2021

Lipoxygenase mediates invasion of intrametastatic lymphatic vessels and propagates lymph node metastasis of human mammary carcinoma xenografts in mouse

artículo científico publicado en 2011

Lymphangiogenesis and Cancer ⬇️

artículo científico publicado el 1 de diciembre de 2011

Lymphatic endothelial cells attenuate inflammation via suppression of dendritic cell maturation

artículo científico publicado en 2016

Lymphatic endothelium in health and disease

scientific article published on 22 July 2008

Lymphatic exosomes promote dendritic cell migration along guidance cues.

artículo científico publicado en 2018

Lymphatic outflow of cerebrospinal fluid is reduced in glioma

artículo científico publicado en 2019

Lymphatic reprogramming of blood vascular endothelium by Kaposi sarcoma–associated herpesvirus

Lymphatic vessels: new targets for the treatment of inflammatory diseases

artículo científico publicado en 2013

Lymphatic-specific expression of dipeptidyl peptidase IV and its dual role in lymphatic endothelial function

artículo científico publicado en 2008

Lymphatics in nanophysiology

artículo científico

Mechanisms of Tumor-Induced Lymphovascular Niche Formation in Draining Lymph Nodes

Mechanisms of lymphatic metastasis

artículo científico publicado en 2014

Microneedles for the Noninvasive Structural and Functional Assessment of Dermal Lymphatic Vessels

artículo científico publicado en 2016

Minimally invasive method for the point-of-care quantification of lymphatic vessel function

scholarly article by Anna K Polomska et al published 21 February 2019 in JCI insight

Molecular mechanisms and imaging of lymphatic metastasis ⬇️

artículo científico publicado el 13 de marzo de 2013

Multidisciplinary Consideration of Potential Pathophysiologic Mechanisms of Paradoxical Erythema with Topical Brimonidine Therapy

artículo científico publicado en 2016

Multifocal lymphangioendotheliomatosis with thrombocytopenia: a newly recognized clinicopathological entity

artículo científico publicado en 2004

Mutation of threonine 34 in mouse podoplanin-Fc reduces CLEC-2 binding and toxicity in vivo while retaining antilymphangiogenic activity

artículo científico publicado en 2014

New insights into the biology and pathology of the cutaneous lymphatic system

artículo científico publicado en 2004

New insights into the molecular control of the lymphatic vascular system and its role in disease

artículo científico publicado en 2006

New use of an old drug: inhibition of breast cancer stem cells by benztropine mesylate

artículo científico publicado en 2016

Nodal lymphangiogenesis and metastasis: Role of tumor-induced lymphatic vessel activation in extramammary Paget's disease

artículo científico publicado en 2009

Novel Blood Vascular Endothelial Subtype-Specific Markers in Human Skin Unearthed by Single-Cell Transcriptomic Profiling

artículo científico publicado en 2022

Nuclear translocation of phosphorylated STAT3 is essential for vascular endothelial growth factor-induced human dermal microvascular endothelial cell migration and tube formation

artículo científico publicado en 2003

Outflow of cerebrospinal fluid is predominantly through lymphatic vessels and is reduced in aged mice.

artículo científico publicado en 2017

Pathways targeting tumor lymphangiogenesis

artículo científico publicado en 2006

Phage-derived fully human monoclonal antibody fragments to human vascular endothelial growth factor-C block its interaction with VEGF receptor-2 and 3.

artículo científico publicado en 2010

Phenotype-based high-content chemical library screening identifies statins as inhibitors of in vivo lymphangiogenesis

artículo científico publicado en 2012

Podoplanin-Fc reduces lymphatic vessel formation in vitro and in vivo and causes disseminated intravascular coagulation when transgenically expressed in the skin

artículo científico publicado en 2010

Polyphyllin D, a steroidal saponin from Paris polyphylla, inhibits endothelial cell functions in vitro and angiogenesis in zebrafish embryos in vivo

artículo científico publicado en 2011

Postnatal Deletion of Podoplanin in Lymphatic Endothelium Results in Blood Filling of the Lymphatic System and Impairs Dendritic Cell Migration to Lymph Nodes

artículo científico publicado en 2016

Prominent Lymphatic Vessel Hyperplasia with Progressive Dysfunction and Distinct Immune Cell Infiltration in Lymphedema

artículo científico publicado en 2016

Prox-1 promotes invasion of kaposiform hemangioendotheliomas

artículo científico publicado en 2008

Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate

artículo científico publicado en 2002

Prox1 promotes lineage-specific expression of fibroblast growth factor (FGF) receptor-3 in lymphatic endothelium: a role for FGF signaling in lymphangiogenesis

scientific journal article

Prox1, master regulator of the lymphatic vasculature phenotype

artículo científico publicado en 2003

Quantitative imaging of lymphatic function with liposomal indocyanine green

artículo científico publicado en 2010

Quantitative measurement of lymphatic function in mice by noninvasive near-infrared imaging of a peripheral vein

artículo científico publicado en 2017

Reduction of lymphatic vessels in photodamaged human skin

artículo científico publicado en 2007

Regulatory T cell transfer ameliorates lymphedema and promotes lymphatic vessel function

artículo científico publicado en 2016

Restoration of lymphatic function rescues obesity in Prox1-haploinsufficient mice

artículo científico publicado en 2016

Single-cell mapping reveals new markers and functions of lymphatic endothelial cells in lymph nodes

scientific article published on 06 April 2020

Sostdc1 Secreted from Cutaneous Lymphatic Vessels Acts as a Paracrine Factor for Hair Follicle Growth

artículo científico publicado en 2022

Stable expression of angiopoietin-1 and other markers by cultured pericytes: phenotypic similarities to a subpopulation of cells in maturing vessels during later stages of angiogenesis in vivo

artículo científico publicado en 2002

Standard grading system for rosacea: report of the National Rosacea Society Expert Committee on the classification and staging of rosacea

artículo científico publicado en 2004

Steering target selectivity and potency by fragment-based de novo drug design

artículo científico publicado en 2013

Stimulation of lymphangiogenesis via VEGFR-3 inhibits chronic skin inflammation

artículo científico publicado en 2010

Stroma formation and angiogenesis by overexpression of growth factors, cytokines, and proteolytic enzymes in human skin grafted to SCID mice

artículo científico publicado en 2003

Systemic anti-VEGF treatment strongly reduces skin inflammation in a mouse model of psoriasis

artículo científico publicado en 2009

Systemic inhibition of tumor growth and angiogenesis by thrombospondin-2 using cell-based antiangiogenic gene therapy.

artículo científico publicado en 2002

T Cell Migration from Inflamed Skin to Draining Lymph Nodes Requires Intralymphatic Crawling Supported by ICAM-1/LFA-1 Interactions

artículo científico publicado en 2017

TScratch: a novel and simple software tool for automated analysis of monolayer wound healing assays

artículo científico publicado en 2009

The Cutaneous Vascular System in Chronic Skin Inflammation ⬇️

artículo científico publicado el 1 de diciembre de 2011

The expression levels of microRNA-361-5p and its target VEGFA are inversely correlated in human cutaneous squamous cell carcinoma

artículo científico publicado en 2012

The formation of lymphatic vessels and its importance in the setting of malignancy

artículo científico publicado en 2002

The lymphatic system in health and disease

artículo científico publicado en 2008

The miR-290-295 cluster suppresses autophagic cell death of melanoma cells ⬇️

artículo científico publicado el 13 de noviembre de 2012

The orphan adhesion G protein-coupled receptor GPR97 regulates migration of lymphatic endothelial cells via the small GTPases RhoA and Cdc42

artículo científico publicado en 2013

The rediscovery of the lymphatic system: old and new insights into the development and biological function of the lymphatic vasculature

artículo científico publicado en 2002

The role of neuropilin-1/semaphorin 3A signaling in lymphatic vessel development and maturation

artículo científico

The α1β1 and α2β1 Integrins Provide Critical Support for Vascular Endothelial Growth Factor Signaling, Endothelial Cell Migration, and Tumor Angiogenesis ⬇️

artículo científico publicado el 1 de enero de 2002

Thrombospondin 2 functions as an endogenous regulator of angiogenesis and inflammation in rheumatoid arthritis

artículo científico publicado en 2004

Thrombospondin-1 selectively inhibits early-stage carcinogenesis and angiogenesis but not tumor lymphangiogenesis and lymphatic metastasis in transgenic mice

artículo científico publicado en 2002

Thrombospondin-2 overexpression in the skin of transgenic mice reduces the susceptibility to chemically induced multistep skin carcinogenesis

scientific article published on 18 January 2014

Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells

artículo científico publicado en 2015

Transcriptional profiling of VEGF-A and VEGF-C target genes in lymphatic endothelium reveals endothelial-specific molecule-1 as a novel mediator of lymphangiogenesis

artículo científico publicado en 2008

Transgenic delivery of VEGF to mouse skin leads to an inflammatory condition resembling human psoriasis

artículo científico publicado en 2003

Transgenic overexpression of VEGF-C induces weight gain and insulin resistance in mice

scientific article published on 11 August 2016

Tumor and lymph node lymphangiogenesis--impact on cancer metastasis

artículo científico publicado en 2006

Tumor lymphangiogenesis and melanoma metastasis

artículo científico publicado en 2008

Tumor lymphangiogenesis and metastasis to lymph nodes induced by cancer cell expression of podoplanin

artículo científico publicado en 2010

Tumor lymphangiogenesis and new drug development

artículo científico

Tumor lymphangiogenesis predicts melanoma metastasis to sentinel lymph nodes

artículo científico publicado en 2005

Tumor lymphangiogenesis: a novel prognostic indicator for cutaneous melanoma metastasis and survival

artículo científico publicado en 2003

Tumor progression: the effects of thrombospondin-1 and -2.

artículo científico publicado en 2004

Tumor-Associated Lymphatic Vessels Upregulate PDL1 to Inhibit T-Cell Activation

artículo científico publicado en 2017

Ultraviolet B-induced skin angiogenesis is associated with a switch in the balance of vascular endothelial growth factor and thrombospondin-1 expression

artículo científico publicado en 2004

Unexpected contribution of lymphatic vessels to promotion of distant metastatic tumor spread

artículo científico publicado en 2018

Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors

artículo científico publicado en 2005

Use of a PEG-conjugated bright near-infrared dye for functional imaging of rerouting of tumor lymphatic drainage after sentinel lymph node metastasis

artículo científico publicado en 2013

VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis

artículo científico publicado en 2005

VEGF-A produced by chronically inflamed tissue induces lymphangiogenesis in draining lymph nodes

artículo científico publicado en 2007

VEGF-A promotes tissue repair-associated lymphatic vessel formation via VEGFR-2 and the alpha1beta1 and alpha2beta1 integrins

artículo científico publicado en 2004

VEGF-C and VEGF-D blockade inhibits inflammatory skin carcinogenesis

artículo científico publicado en 2013

VEGF-C-induced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sites

artículo científico publicado en 2006

Vascular Endothelial Growth Factor-C (VEGF-C) and its Receptors KDR and flt-4 are Expressed in AIDS-Associated Kaposi’s Sarcoma

article

Vascular endothelial growth factor-A mediates ultraviolet B-induced impairment of lymphatic vessel function

artículo científico publicado en 2006

Walking the Line: A Fibronectin Fiber-Guided Assay to Probe Early Steps of (Lymph)angiogenesis

artículo científico publicado en 2015

Watching lymphatic vessels grow by making them glow ⬇️

artículo científico publicado el 29 de noviembre de 2011

miR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivo

artículo científico publicado en 2010

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