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Lista de obras de Heather M Stringham

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

artículo científico publicado en 2017

A Partial Loss-of-Function Variant in AKT2 Is Associated With Reduced Insulin-Mediated Glucose Uptake in Multiple Insulin-Sensitive Tissues: A Genotype-Based Callback Positron Emission Tomography Study

artículo científico publicado en 2017

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A genome-wide association search for type 2 diabetes genes in African Americans

artículo científico publicado en 2012

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

artículo científico publicado en 2016

Additive effects of genetic variation in GCK and G6PC2 on insulin secretion and fasting glucose

artículo científico publicado en 2009

Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences

scientific article published on 11 September 2020

Age-related clonal hematopoiesis associated with adverse outcomes

artículo científico publicado en 2014

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

artículo científico publicado en 2017

Association of Transcription Factor 7-Like 2 (TCF7L2) Variants With Type 2 Diabetes in a Finnish Sample

article

Biological, clinical and population relevance of 95 loci for blood lipids

artículo científico publicado en 2010

Common Variants in Maturity-Onset Diabetes of the Young Genes Contribute to Risk of Type 2 Diabetes in Finns

article

Common variants at 30 loci contribute to polygenic dyslipidemia

artículo científico publicado en 2009

Common variants in the GDF5-UQCC region are associated with variation in human height

artículo científico publicado en 2008

Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study

artículo científico publicado en 2017

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.

artículo científico publicado en 2009

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2016

Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scholarly article published in Nature Genetics

Defining the role of common variation in the genomic and biological architecture of adult human height

artículo científico publicado en 2014

Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans

artículo científico publicado en 2010

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2011

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2018

Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion

artículo científico publicado en 2012

Exome chip meta-analysis fine maps causal variants and elucidates the genetic architecture of rare coding variants in smoking and alcohol use

artículo científico publicado en 2018

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

article by Jason Flannick et al published 22 May 2019 in Nature

Exome-wide association study of plasma lipids in >300,000 individuals

artículo científico publicado en 2017

Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits

artículo científico publicado en 2017

Genetic evidence of assortative mating in humans

article

Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes

artículo científico publicado en 2009

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

artículo científico publicado en 2015

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

artículo científico publicado en 2011

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

artículo científico publicado en 2009

Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci

artículo científico publicado en 2022

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

artículo científico publicado en 2017

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

artículo científico publicado en 2014

Hundreds of variants clustered in genomic loci and biological pathways affect human height

artículo científico publicado en 2010

IL6 gene promoter polymorphisms and type 2 diabetes: joint analysis of individual participants' data from 21 studies

artículo científico publicado en 2006

Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus

artículo científico publicado en 2015

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

artículo científico publicado en 2013

Identification of seven novel loci associated with amino acid levels using single-variant and gene-based tests in 8545 Finnish men from the METSIM study.

artículo científico publicado en 2018

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity

artículo científico publicado en 2013

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

artículo científico publicado en 2012

Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index

artículo científico publicado en 2009

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

artículo científico publicado en 2012

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

artículo científico publicado en 2012

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

artículo científico publicado en 2014

Meta-Analysis of Genome-wide Linkage Studies in BMI and Obesity*

article

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2010

Meta-analysis of gene-environment interaction exploiting gene-environment independence across multiple case-control studies

artículo científico publicado en 2017

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

artículo científico publicado en 2008

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

artículo científico publicado en 2019

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

article

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

artículo científico publicado en 2019

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

New genetic loci link adipose and insulin biology to body fat distribution

artículo científico publicado en 2015

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

artículo científico publicado en 2008

No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels

artículo científico publicado en 2012

Novel association of TM6SF2 rs58542926 genotype with increased serum tyrosine levels and decreased apoB-100 particles in Finns

artículo científico publicado en 2017

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

artículo científico publicado en 2018

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children

artículo científico publicado en 2011

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

artículo científico publicado en 2018

Rare and low-frequency coding variants alter human adult height

artículo científico publicado en 2017

Re-sequencing expands our understanding of the phenotypic impact of variants at GWAS loci

scientific article published on 30 January 2014

Screening of 134 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes replicates association with 12 SNPs in nine genes

artículo científico publicado en 2007

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2017

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

artículo científico publicado en 2009

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2015

The genetic architecture of type 2 diabetes

artículo científico publicado en 2016

The genetic regulatory signature of type 2 diabetes in human skeletal muscle

scientific article published on 29 June 2016

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

artículo científico publicado en 2016

The role of environmental heterogeneity in meta-analysis of gene-environment interactions with quantitative traits

artículo científico publicado en 2014

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

artículo científico publicado en 2016

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

artículo científico publicado en 2010

Variants in MTNR1B influence fasting glucose levels

artículo científico publicado en 2008

Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels

artículo científico publicado en 2008

X-linked recessive atrophic macular degeneration from RPGR mutation

artículo científico publicado en 2002

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