Lista de obras - Jorge L Del-Aguila - Dominio Público Uruguay

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.

artículo científico publicado en 2017

A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain

artículo científico publicado en 2019

Alzheimer's disease: rare variants with large effect sizes

artículo científico

An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations

artículo científico publicado en 2019

Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease

artículo científico publicado en 2017

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

artículo científico publicado en 2017

Ascertaining perturbations in microglial expression profiles using single‐nuclei RNA‐seq from human brains

artículo científico publicado en 2020

Assessment of the Genetic Architecture of Alzheimer's Disease Risk in Rate of Memory Decline.

artículo científico publicado en 2018

Chi3l1/YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer's disease pathogenesis

artículo científico publicado en 2020

Chitinase-3-like 1 protein (CHI3L1) locus influences cerebrospinal fluid levels of YKL-40.

artículo científico publicado en 2016

Evaluation of Gene-Based Family-Based Methods to Detect Novel Genes Associated With Familial Late Onset Alzheimer Disease.

artículo científico publicado en 2018

Examination of the Effect of Rare Variants in TREM2, ABI3, and PLCG2 in LOAD Through Multiple Phenotypes

artículo científico publicado en 2020

Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits.

artículo científico publicado en 2016

Genetic variants associated with Alzheimer's disease confer different cerebral cortex cell-type population structure.

artículo científico publicado en 2018

Genome-wide association study for variants that modulate relationships between cerebrospinal fluid amyloid-beta 42, tau, and p-tau levels

artículo científico publicado en 2018

Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers

artículo científico publicado en 2017

Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging

artículo científico publicado en 2018

Genome-wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways

artículo científico publicado en 2020

Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP

artículo científico publicado en 2018

Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels.

artículo científico publicado en 2017

Polygenic risk score of sporadic late-onset Alzheimer's disease reveals a shared architecture with the familial and early-onset forms.

artículo científico publicado en 2017

Role of ABCA7 loss-of-function variant in Alzheimer's disease: a replication study in European-Americans

artículo científico publicado en 2015

SORL1 variants across Alzheimer's disease European American cohorts

artículo científico publicado en 2016

Sex-specific genetic predictors of Alzheimer's disease biomarkers

artículo científico publicado en 2018

Single‐nuclei RNA‐seq of brains carriers of high‐risk variants and Mendelian mutations

artículo científico publicado en 2020

TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers

artículo científico publicado en 2019

The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk

scientific article published on 01 August 2019

The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion

scientific article published on 27 August 2019

Lista de obras de Jorge L Del-Aguila

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.

A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain

Alzheimer's disease: rare variants with large effect sizes

An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations

Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

Ascertaining perturbations in microglial expression profiles using single‐nuclei RNA‐seq from human brains

Assessment of the Genetic Architecture of Alzheimer's Disease Risk in Rate of Memory Decline.

Chi3l1/YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer's disease pathogenesis

Chitinase-3-like 1 protein (CHI3L1) locus influences cerebrospinal fluid levels of YKL-40.

Evaluation of Gene-Based Family-Based Methods to Detect Novel Genes Associated With Familial Late Onset Alzheimer Disease.

Examination of the Effect of Rare Variants in TREM2, ABI3, and PLCG2 in LOAD Through Multiple Phenotypes

Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits.

Genetic variants associated with Alzheimer's disease confer different cerebral cortex cell-type population structure.

Genome-wide association study for variants that modulate relationships between cerebrospinal fluid amyloid-beta 42, tau, and p-tau levels

Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers

Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging

Genome-wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways

Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP

Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels.

Polygenic risk score of sporadic late-onset Alzheimer's disease reveals a shared architecture with the familial and early-onset forms.

Role of ABCA7 loss-of-function variant in Alzheimer's disease: a replication study in European-Americans

SORL1 variants across Alzheimer's disease European American cohorts

Sex-specific genetic predictors of Alzheimer's disease biomarkers

Single‐nuclei RNA‐seq of brains carriers of high‐risk variants and Mendelian mutations

TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers

The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk

The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion