Lista de obras - Manuel Comabella Lopez - Dominio Público Uruguay

A functional variant that affects exon-skipping and protein expression of SP140 as genetic mechanism predisposing to multiple sclerosis.

artículo científico publicado en 2015

A genomic screen of Spanish multiple sclerosis patients reveals multiple loci associated with the disease

artículo científico publicado en 2003

Analysis of Plasminogen Genetic Variants in Multiple Sclerosis Patients

artículo científico publicado en 2016

Ancient and recent selective pressures shaped genetic diversity at AIM2-like nucleic acid sensors.

artículo científico publicado en 2014

Breast regression protein-39 is not required for experimental autoimmune encephalomyelitis induction.

artículo científico publicado en 2015

COVID-19 in MS patients: susceptibility, severity risk factors and serological response

scientific article published on 19 December 2020

Changes in matrix metalloproteinases and their inhibitors during interferon-beta treatment in multiple sclerosis

scientific article published on 21 October 2008

Circulating microparticles reflect treatment effects and clinical status in multiple sclerosis

scientific article published on 01 January 2014

Clinicogenomic factors of biotherapy immunogenicity in autoimmune disease: A prospective multicohort study of the ABIRISK consortium

artículo científico publicado en 2020

Cognitive impairment in early stages of multiple sclerosis is associated with high cerebrospinal fluid levels of chitinase 3-like 1 and neurofilament light chain

artículo científico publicado en 2018

Consensus guidelines for lumbar puncture in patients with neurological diseases

artículo científico publicado en 2017

Cytokine profiles show heterogeneity of interferon-β response in multiple sclerosis patients

artículo científico publicado en 2016

Exome sequencing study in patients with multiple sclerosis reveals variants associated with disease course

artículo científico publicado en 2018

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

artículo científico publicado en 2011

Genome-wide pharmacogenomic analysis of the response to interferon beta therapy in multiple sclerosis.

artículo científico publicado en 2008

Genome-wide significant association of ANKRD55 rs6859219 and multiple sclerosis risk

artículo científico publicado en 2013

Genome-wide significant association with seven novel multiple sclerosis risk loci

artículo científico publicado en 2015

HLA alleles as biomarkers of high-titre neutralising antibodies to interferon-β therapy in multiple sclerosis

artículo científico publicado en 2014

Identification of a functional variant in the KIF5A-CYP27B1-METTL1-FAM119B locus associated with multiple sclerosis

artículo científico publicado en 2012

Immunoglobulin M oligoclonal bands: biomarker of targetable inflammation in primary progressive multiple sclerosis.

artículo científico publicado en 2014

Implication of the Toll-like receptor 4 pathway in the response to interferon-β in multiple sclerosis.

artículo científico publicado en 2011

Influence of the LILRA3 Deletion on Multiple Sclerosis Risk: Original Data and Meta-Analysis.

artículo científico publicado en 2015

Lipid-specific immunoglobulin M bands in cerebrospinal fluid are associated with a reduced risk of developing progressive multifocal leukoencephalopathy during treatment with natalizumab

artículo científico publicado en 2015

Low frequency and rare coding variation contributes to multiple sclerosis risk

MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis

artículo científico publicado en 2013

N-acetylaspartate and neurofilaments as biomarkers of axonal damage in patients with progressive forms of multiple sclerosis

artículo científico publicado en 2014

Natalizumab-related anaphylactoid reactions in MS patients are associated with HLA class II alleles.

artículo científico publicado en 2014

Neurofilament ELISA validation

artículo científico publicado en 2009

Neurofilament light chain level is a weak risk factor for the development of MS.

artículo científico publicado en 2016

Neurofilaments as biomarkers in neurological disorders

article by Michael Khalil et al published 31 August 2018 in Nature Reviews Neurology

No association of IFI16 (interferon-inducible protein 16) variants with susceptibility to multiple sclerosis

scientific article published on 16 April 2014

Pharmacogenomic study in patients with multiple sclerosis: Responders and nonresponders to IFN-β.

artículo científico publicado en 2015

Power estimation for non-standardized multisite studies

artículo científico publicado en 2016

Radiologically isolated syndrome: targeting miRNAs as prognostic biomarkers

scientific article published on 08 December 2020

Replication study of 10 genes showing evidence for association with multiple sclerosis: validation of TMEM39A, IL12B and CLBL genes

article

TNFRSF1A polymorphisms rs1800693 and rs4149584 in patients with multiple sclerosis.

artículo científico publicado en 2013

Targeted resequencing reveals rare variants enrichment in multiple sclerosis susceptibility genes

artículo científico publicado en 2020

The Multiple Sclerosis Genomic Map: Role of peripheral immune cells and resident microglia in susceptibility

scholarly article published 13 July 2017

The long-term outcomes of CIS patients in the Barcelona inception cohort: Looking back to recognize aggressive MS

artículo científico publicado en 2019

The value of oligoclonal bands in the multiple sclerosis diagnostic criteria.

artículo científico publicado en 2018

Transcription-based prediction of response to IFNbeta using supervised computational methods

artículo científico publicado en 2005

Treatment with MOG-DNA vaccines induces CD4+CD25+FoxP3+ regulatory T cells and up-regulates genes with neuroprotective functions in experimental autoimmune encephalomyelitis.

artículo científico publicado en 2012

Up-regulation of inducible heat shock protein-70 expression in multiple sclerosis patients.

artículo científico publicado en 2013

Lista de obras de Manuel Comabella Lopez

A functional variant that affects exon-skipping and protein expression of SP140 as genetic mechanism predisposing to multiple sclerosis.

A genomic screen of Spanish multiple sclerosis patients reveals multiple loci associated with the disease

Analysis of Plasminogen Genetic Variants in Multiple Sclerosis Patients

Ancient and recent selective pressures shaped genetic diversity at AIM2-like nucleic acid sensors.

Breast regression protein-39 is not required for experimental autoimmune encephalomyelitis induction.

COVID-19 in MS patients: susceptibility, severity risk factors and serological response

Changes in matrix metalloproteinases and their inhibitors during interferon-beta treatment in multiple sclerosis

Circulating microparticles reflect treatment effects and clinical status in multiple sclerosis

Clinicogenomic factors of biotherapy immunogenicity in autoimmune disease: A prospective multicohort study of the ABIRISK consortium

Cognitive impairment in early stages of multiple sclerosis is associated with high cerebrospinal fluid levels of chitinase 3-like 1 and neurofilament light chain

Consensus guidelines for lumbar puncture in patients with neurological diseases

Cytokine profiles show heterogeneity of interferon-β response in multiple sclerosis patients

Exome sequencing study in patients with multiple sclerosis reveals variants associated with disease course

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

Genome-wide pharmacogenomic analysis of the response to interferon beta therapy in multiple sclerosis.

Genome-wide significant association of ANKRD55 rs6859219 and multiple sclerosis risk

Genome-wide significant association with seven novel multiple sclerosis risk loci

HLA alleles as biomarkers of high-titre neutralising antibodies to interferon-β therapy in multiple sclerosis

Identification of a functional variant in the KIF5A-CYP27B1-METTL1-FAM119B locus associated with multiple sclerosis

Immunoglobulin M oligoclonal bands: biomarker of targetable inflammation in primary progressive multiple sclerosis.

Implication of the Toll-like receptor 4 pathway in the response to interferon-β in multiple sclerosis.

Influence of the LILRA3 Deletion on Multiple Sclerosis Risk: Original Data and Meta-Analysis.

Lipid-specific immunoglobulin M bands in cerebrospinal fluid are associated with a reduced risk of developing progressive multifocal leukoencephalopathy during treatment with natalizumab

Low frequency and rare coding variation contributes to multiple sclerosis risk

MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis

N-acetylaspartate and neurofilaments as biomarkers of axonal damage in patients with progressive forms of multiple sclerosis

Natalizumab-related anaphylactoid reactions in MS patients are associated with HLA class II alleles.

Neurofilament ELISA validation

Neurofilament light chain level is a weak risk factor for the development of MS.

Neurofilaments as biomarkers in neurological disorders

No association of IFI16 (interferon-inducible protein 16) variants with susceptibility to multiple sclerosis

Pharmacogenomic study in patients with multiple sclerosis: Responders and nonresponders to IFN-β.

Power estimation for non-standardized multisite studies

Radiologically isolated syndrome: targeting miRNAs as prognostic biomarkers

Replication study of 10 genes showing evidence for association with multiple sclerosis: validation of TMEM39A, IL12B and CLBL genes

TNFRSF1A polymorphisms rs1800693 and rs4149584 in patients with multiple sclerosis.

Targeted resequencing reveals rare variants enrichment in multiple sclerosis susceptibility genes

The Multiple Sclerosis Genomic Map: Role of peripheral immune cells and resident microglia in susceptibility

The long-term outcomes of CIS patients in the Barcelona inception cohort: Looking back to recognize aggressive MS

The value of oligoclonal bands in the multiple sclerosis diagnostic criteria.

Transcription-based prediction of response to IFNbeta using supervised computational methods

Treatment with MOG-DNA vaccines induces CD4+CD25+FoxP3+ regulatory T cells and up-regulates genes with neuroprotective functions in experimental autoimmune encephalomyelitis.

Up-regulation of inducible heat shock protein-70 expression in multiple sclerosis patients.