Lista de obras - Miguel A Penalva - Dominio Público Uruguay

A fungal perspective on human inborn errors of metabolism: alkaptonuria and beyond.

artículo científico publicado en 2001

A lacZ reporter fusion method for the genetic analysis of regulatory mutations in pathways of fungal secondary metabolism and its application to the Aspergillus nidulans penicillin pathway ⬇️

artículo científico publicado el 1 de noviembre de 1995

A lipid-managing program maintains a stout Spitzenkörper.

artículo científico publicado en 2015

Activation of the Aspergillus PacC transcription factor in response to alkaline ambient pH requires proteolysis of the carboxy-terminal moiety

artículo científico publicado en 1995

Activation of the Aspergillus PacC zinc finger transcription factor requires two proteolytic steps.

artículo científico publicado en 2002

Acute inactivation of the Aspergillus nidulans Golgi membrane fusion machinery: correlation of apical extension arrest and tip swelling with cisternal disorganization.

artículo científico publicado en 2013

Adaptation of the Tokuyasu method for the ultrastructural study and immunogold labelling of filamentous fungi.

artículo científico publicado en 2011

AgtA, the dicarboxylic amino acid transporter of Aspergillus nidulans, is concertedly down-regulated by exquisite sensitivity to nitrogen metabolite repression and ammonium-elicited endocytosis.

artículo científico publicado en 2009

Ambient pH gene regulation in fungi: making connections.

artículo científico publicado en 2008

Ambient pH signaling regulates nuclear localization of the Aspergillus nidulans PacC transcription factor

artículo científico publicado en 2001

An isoprenylation and palmitoylation motif promotes intraluminal vesicle delivery of proteins in cells from distant species

artículo científico publicado en 2014

An ordered pathway for the assembly of fungal ESCRT-containing ambient pH signalling complexes at the plasma membrane

artículo científico publicado en 2012

Analysis of a novel calcium auxotrophy in Aspergillus nidulans.

artículo científico publicado en 2010

Arrestin-related proteins mediate pH signaling in fungi.

artículo científico publicado en 2005

Aspergillus RabB Rab5 integrates acquisition of degradative identity with the long distance movement of early endosomes

artículo científico publicado en 2010

Aspergillus nidulans Ambient pH Signaling Does Not Require Endocytosis

artículo científico publicado en 2015

Aspergillus nidulans BapH is a RAB11 effector that connects membranes in the Spitzenkörper with basal autophagy.

artículo científico publicado en 2017

Aspergillus nidulans CkiA is an essential casein kinase I required for delivery of amino acid transporters to the plasma membrane.

artículo científico publicado en 2012

COPI localizes to the early Golgi in Aspergillus nidulans

scientific article published on 11 December 2018

Carbon regulation of penicillin biosynthesis in Aspergillus nidulans: a minor effect of mutations in creB and creC

scientific article published on 01 February 1995

Cell Biology of Hyphal Growth

artículo científico publicado en 2017

Characterization of Aspergillus nidulans DidB Did2, a non-essential component of the multivesicular body pathway

artículo científico publicado en 2010

Characterization of Aspergillus nidulans RabC/Rab6.

artículo científico publicado en 2011

Characterization of Aspergillus nidulans TRAPPs uncovers unprecedented similarities between fungi and metazoans and reveals the modular assembly of TRAPPII

artículo científico publicado en 2019

Cloning and characterization of the isopenicillin N synthetase gene mediating the formation of the beta-lactam ring in Aspergillus nidulans.

artículo científico publicado en 1987

Conditional inactivation ofAspergillus nidulans sarASAR1uncovers the morphogenetic potential of regulating endoplasmic reticulum (ER) exit

scientific article published on 30 December 2014

Crystal structure of human homogentisate dioxygenase

artículo científico publicado en 2000

Current challenges of research on filamentous fungi in relation to human welfare and a sustainable bio-economy: a white paper.

artículo científico publicado en 2016

Cytoplasmic dynein and early endosome transport

artículo científico publicado en 2015

Endocytic machinery protein SlaB is dispensable for polarity establishment but necessary for polarity maintenance in hyphal tip cells of Aspergillus nidulans

artículo científico publicado en 2010

Endocytic recycling via the TGN underlies the polarized hyphal mode of life.

artículo científico publicado en 2018

Endocytosis in filamentous fungi: Cinderella gets her reward.

scientific article published on October 2010

Endosomal maturation by Rab conversion in Aspergillus nidulans is coupled to dynein-mediated basipetal movement

artículo científico publicado en 2012

Erratum: Corrigendum: Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus

artículo científico publicado en 2006

Establishment of the ambient pH signaling complex in Aspergillus nidulans: PalI assists plasma membrane localization of PalH.

artículo científico publicado en 2007

Evidence for the direct involvement of the proteasome in the proteolytic processing of the Aspergillus nidulans zinc finger transcription factor PacC.

artículo científico publicado en 2007

Expression of fungal genes involved in penicllin biosynthesis

artículo científico

Factors involved in the initiation of phage phi 29 DNA replication in vitro: requirement of the gene 2 product for the formation of the protein p3-dAMP complex.

artículo científico publicado en 1983

Functional analysis of MCCA and MCCB mutations causing methylcrotonylglycinuria.

artículo científico publicado en 2003

Fungal metabolic model for 3-methylcrotonyl-CoA carboxylase deficiency.

artículo científico publicado en 2003

Fungal metabolic model for type I 3-methylglutaconic aciduria

artículo científico publicado en 2004

Further characterization of the signaling proteolysis step in the Aspergillus nidulans pH signal transduction pathway.

artículo científico publicado en 2007

GBF/Gea mutant with a single substitution sustains fungal growth in the absence of BIG/Sec7.

artículo científico publicado en 2014

Genetic dissection of the secretory route followed by a fungal extracellular glycosyl hydrolase

artículo científico publicado en 2018

Genetic studies on the physiological role of CORVET in Aspergillus nidulans.

artículo científico publicado en 2017

Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus

artículo científico publicado en 2005

HookA is a novel dynein-early endosome linker critical for cargo movement in vivo.

artículo científico publicado en 2014

Identification of the guanine nucleotide exchange factor for SAR1 in the filamentous fungal model Aspergillus nidulans

artículo científico publicado en 2019

Liaison alcaline: Pals entice non-endosomal ESCRTs to the plasma membrane for pH signaling

artículo científico publicado en 2014

Live-cell imaging of Aspergillus nidulans autophagy: RAB1 dependence, Golgi independence and ER involvement

artículo científico publicado en 2013

Long-Distance Movement of Aspergillus nidulans Early Endosomes on Microtubule Tracks

artículo científico publicado en 2008

Maturation of late Golgi cisternae into RabE(RAB11) exocytic post-Golgi carriers visualized in vivo.

artículo científico publicado en 2014

Molecular Characterization of a Gene Encoding a Homogentisate Dioxygenase from Aspergillus nidulans and Identification of Its Human and Plant Homologues ⬇️

artículo científico publicado el 8 de septiembre de 1995

Molecular basis of resistance to the microtubule-depolymerizing antitumor compound plocabulin.

artículo científico publicado en 2018

Molecular characterization of a fungal secondary metabolism promoter: transcription of the Aspergillus nidulans isopenicillin N synthetase gene is modulated by upstream negative elements

article

Molecular cloning of the uaY regulatory gene of Aspergillus nidulans reveals a favoured region for DNA insertions ⬇️

artículo científico publicado el 1 de diciembre de 1991

Mutation and polymorphism analysis of the human homogentisate 1, 2-dioxygenase gene in alkaptonuria patients.

artículo científico publicado en 1998

Mutational analysis of the Aspergillus ambient pH receptor PalH underscores its potential as a target for antifungal compounds.

artículo científico publicado en 2016

Mutational analysis of the pH signal transduction component PalC of Aspergillus nidulans supports distant similarity to BRO1 domain family members.

artículo científico publicado en 2005

NapA and NapB are the Aspergillus nidulans Nap/SET family members and NapB is a nuclear protein specifically interacting with importin alpha.

artículo científico publicado en 2007

New interfacial microtubule inhibitors of marine origin, PM050489/PM060184, with potent antitumor activity and a distinct mechanism.

artículo científico publicado en 2013

On how a transcription factor can avoid its proteolytic activation in the absence of signal transduction.

artículo científico publicado en 2000

Organization and dynamics of the Aspergillus nidulans Golgi during apical extension and mitosis.

artículo científico publicado en 2009

Overlap of nuclear localisation signal and specific DNA-binding residues within the zinc finger domain of PacC.

artículo científico publicado en 2003

PalC, one of two Bro1 domain proteins in the fungal pH signalling pathway, localizes to cortical structures and binds Vps32.

artículo científico publicado en 2007

Physiological involvement in pH signaling of Vps24-mediated recruitment of Aspergillus PalB cysteine protease to ESCRT-III.

artículo científico publicado en 2008

Preferential localization of the endocytic internalization machinery to hyphal tips underlies polarization of the actin cytoskeleton in Aspergillus nidulans

artículo científico publicado en 2008

Probing the effect of tip pressure on fungal growth: Application to Aspergillus nidulans

artículo científico publicado en 2017

Ras GTPase-activating protein regulation of actin cytoskeleton and hyphal polarity in Aspergillus nidulans

artículo científico publicado en 2007

Recent advances in the characterization of ambient pH regulation of gene expression in filamentous fungi and yeasts

artículo científico publicado en 2004

Receptor-independent Ambient pH signaling by ubiquitin attachment to fungal arrestin-like PalF.

artículo científico publicado en 2010

Recognizing gene regulation by ambient pH

scientific article published on 01 October 2003

Refining the pH response in Aspergillus nidulans: a modulatory triad involving PacX, a novel zinc binuclear cluster protein

artículo científico publicado en 2015

Regulation of gene expression by ambient pH in filamentous fungi and yeasts

artículo científico publicado en 2002

Rescue of Aspergillus nidulans severely debilitating null mutations in ESCRT-0, I, II and III genes by inactivation of a salt-tolerance pathway allows examination of ESCRT gene roles in pH signalling

artículo científico publicado en 2011

Searching for gold beyond mitosis: Mining intracellular membrane traffic in Aspergillus nidulans

artículo científico

Sequences of isopenicillin N synthetase genes suggest horizontal gene transfer from prokaryotes to eukaryotes

article

Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae

artículo científico publicado en 2005

Specific DNA recognition by the Aspergillus nidulans three zinc finger transcription factor PacC.

artículo científico publicado en 1997

Spectrophotometric determination of homogentisate using Aspergillus nidulans homogentisate dioxygenase

artículo científico publicado en 1997

Structural and functional analysis of mutations in alkaptonuria

artículo científico publicado en 2000

Structure of protein-containing replicative intermediates of Bacillus subtilis phage phi 29 DNA

scientific article published on 01 January 1982

TRAPPII regulates exocytic Golgi exit by mediating nucleotide exchange on the Ypt31 ortholog RabERAB11.

artículo científico publicado en 2015

The Aspergillus nidulans peripheral ER: disorganization by ER stress and persistence during mitosis

artículo científico publicado en 2013

The Aspergillus nidulans syntaxin PepA(Pep12) is regulated by two Sec1/Munc-18 proteins to mediate fusion events at early endosomes, late endosomes and vacuoles

artículo científico publicado en 2015

The microtubule plus-end localization of Aspergillus dynein is important for dynein-early-endosome interaction but not for dynein ATPase activation.

artículo científico publicado en 2010

The p25 subunit of the dynactin complex is required for dynein-early endosome interaction

artículo científico publicado en 2011

The protein covalently linked to the 5' termini of the DNA of Bacillus subtilis phage phi 29 is involved in the initiation of DNA replication

artículo científico publicado en 1980

The tip growth apparatus of Aspergillus nidulans

artículo científico publicado en 2008

Three binding sites for the Aspergillus nidulans PacC zinc-finger transcription factor are necessary and sufficient for regulation by ambient pH of the isopenicillin N synthase gene promoter

article

Tracing the endocytic pathway of Aspergillus nidulans with FM4-64.

artículo científico publicado en 2005

Tracking exocytosis of a GPI-anchored protein in Aspergillus nidulans

scientific article published on 09 September 2020

Transformation in Penicillium chrysogenum

artículo científico publicado en 1987

Transport of fungal RAB11 secretory vesicles involves myosin-5, dynein/dynactin/p25, and kinesin-1 and is independent of kinesin-3

artículo científico publicado en 2017

Triazolopyrimidines Are Microtubule-Stabilizing Agents that Bind the Vinca Inhibitor Site of Tubulin

artículo científico publicado en 2017

YPXL/I is a protein interaction motif recognized by aspergillus PalA and its human homologue, AIP1/Alix

artículo científico publicado en 2003

pH regulation in Aspergillus and parallels with higher eukaryotic regulatory systems.

artículo científico publicado en 2003

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

Guía para el uso y la interpretación de ensayos para el seguimiento de la autofagia (4ª edición)

artículo científico

Lista de obras de Miguel A Penalva

A fungal perspective on human inborn errors of metabolism: alkaptonuria and beyond.

A lacZ reporter fusion method for the genetic analysis of regulatory mutations in pathways of fungal secondary metabolism and its application to the Aspergillus nidulans penicillin pathway ⬇️

A lipid-managing program maintains a stout Spitzenkörper.

Activation of the Aspergillus PacC transcription factor in response to alkaline ambient pH requires proteolysis of the carboxy-terminal moiety

Activation of the Aspergillus PacC zinc finger transcription factor requires two proteolytic steps.

Acute inactivation of the Aspergillus nidulans Golgi membrane fusion machinery: correlation of apical extension arrest and tip swelling with cisternal disorganization.

Adaptation of the Tokuyasu method for the ultrastructural study and immunogold labelling of filamentous fungi.

AgtA, the dicarboxylic amino acid transporter of Aspergillus nidulans, is concertedly down-regulated by exquisite sensitivity to nitrogen metabolite repression and ammonium-elicited endocytosis.

Ambient pH gene regulation in fungi: making connections.

Ambient pH signaling regulates nuclear localization of the Aspergillus nidulans PacC transcription factor

An isoprenylation and palmitoylation motif promotes intraluminal vesicle delivery of proteins in cells from distant species

An ordered pathway for the assembly of fungal ESCRT-containing ambient pH signalling complexes at the plasma membrane

Analysis of a novel calcium auxotrophy in Aspergillus nidulans.

Arrestin-related proteins mediate pH signaling in fungi.

Aspergillus RabB Rab5 integrates acquisition of degradative identity with the long distance movement of early endosomes

Aspergillus nidulans Ambient pH Signaling Does Not Require Endocytosis

Aspergillus nidulans BapH is a RAB11 effector that connects membranes in the Spitzenkörper with basal autophagy.

Aspergillus nidulans CkiA is an essential casein kinase I required for delivery of amino acid transporters to the plasma membrane.

COPI localizes to the early Golgi in Aspergillus nidulans

Carbon regulation of penicillin biosynthesis in Aspergillus nidulans: a minor effect of mutations in creB and creC

Cell Biology of Hyphal Growth

Characterization of Aspergillus nidulans DidB Did2, a non-essential component of the multivesicular body pathway

Characterization of Aspergillus nidulans RabC/Rab6.

Characterization of Aspergillus nidulans TRAPPs uncovers unprecedented similarities between fungi and metazoans and reveals the modular assembly of TRAPPII

Cloning and characterization of the isopenicillin N synthetase gene mediating the formation of the beta-lactam ring in Aspergillus nidulans.

Conditional inactivation ofAspergillus nidulans sarASAR1uncovers the morphogenetic potential of regulating endoplasmic reticulum (ER) exit

Crystal structure of human homogentisate dioxygenase

Current challenges of research on filamentous fungi in relation to human welfare and a sustainable bio-economy: a white paper.

Cytoplasmic dynein and early endosome transport

Endocytic machinery protein SlaB is dispensable for polarity establishment but necessary for polarity maintenance in hyphal tip cells of Aspergillus nidulans

Endocytic recycling via the TGN underlies the polarized hyphal mode of life.

Endocytosis in filamentous fungi: Cinderella gets her reward.

Endosomal maturation by Rab conversion in Aspergillus nidulans is coupled to dynein-mediated basipetal movement

Erratum: Corrigendum: Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus

Establishment of the ambient pH signaling complex in Aspergillus nidulans: PalI assists plasma membrane localization of PalH.

Evidence for the direct involvement of the proteasome in the proteolytic processing of the Aspergillus nidulans zinc finger transcription factor PacC.

Expression of fungal genes involved in penicllin biosynthesis

Factors involved in the initiation of phage phi 29 DNA replication in vitro: requirement of the gene 2 product for the formation of the protein p3-dAMP complex.

Functional analysis of MCCA and MCCB mutations causing methylcrotonylglycinuria.

Fungal metabolic model for 3-methylcrotonyl-CoA carboxylase deficiency.

Fungal metabolic model for type I 3-methylglutaconic aciduria

Further characterization of the signaling proteolysis step in the Aspergillus nidulans pH signal transduction pathway.

GBF/Gea mutant with a single substitution sustains fungal growth in the absence of BIG/Sec7.

Genetic dissection of the secretory route followed by a fungal extracellular glycosyl hydrolase

Genetic studies on the physiological role of CORVET in Aspergillus nidulans.

Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus

HookA is a novel dynein-early endosome linker critical for cargo movement in vivo.

Identification of the guanine nucleotide exchange factor for SAR1 in the filamentous fungal model Aspergillus nidulans

Liaison alcaline: Pals entice non-endosomal ESCRTs to the plasma membrane for pH signaling

Live-cell imaging of Aspergillus nidulans autophagy: RAB1 dependence, Golgi independence and ER involvement

Long-Distance Movement of Aspergillus nidulans Early Endosomes on Microtubule Tracks

Maturation of late Golgi cisternae into RabE(RAB11) exocytic post-Golgi carriers visualized in vivo.

Molecular Characterization of a Gene Encoding a Homogentisate Dioxygenase from Aspergillus nidulans and Identification of Its Human and Plant Homologues ⬇️

Molecular basis of resistance to the microtubule-depolymerizing antitumor compound plocabulin.

Molecular characterization of a fungal secondary metabolism promoter: transcription of the Aspergillus nidulans isopenicillin N synthetase gene is modulated by upstream negative elements

Molecular cloning of the uaY regulatory gene of Aspergillus nidulans reveals a favoured region for DNA insertions ⬇️

Mutation and polymorphism analysis of the human homogentisate 1, 2-dioxygenase gene in alkaptonuria patients.

Mutational analysis of the Aspergillus ambient pH receptor PalH underscores its potential as a target for antifungal compounds.

Mutational analysis of the pH signal transduction component PalC of Aspergillus nidulans supports distant similarity to BRO1 domain family members.

NapA and NapB are the Aspergillus nidulans Nap/SET family members and NapB is a nuclear protein specifically interacting with importin alpha.

New interfacial microtubule inhibitors of marine origin, PM050489/PM060184, with potent antitumor activity and a distinct mechanism.

On how a transcription factor can avoid its proteolytic activation in the absence of signal transduction.

Organization and dynamics of the Aspergillus nidulans Golgi during apical extension and mitosis.

Overlap of nuclear localisation signal and specific DNA-binding residues within the zinc finger domain of PacC.

PalC, one of two Bro1 domain proteins in the fungal pH signalling pathway, localizes to cortical structures and binds Vps32.

Physiological involvement in pH signaling of Vps24-mediated recruitment of Aspergillus PalB cysteine protease to ESCRT-III.

Preferential localization of the endocytic internalization machinery to hyphal tips underlies polarization of the actin cytoskeleton in Aspergillus nidulans

Probing the effect of tip pressure on fungal growth: Application to Aspergillus nidulans

Ras GTPase-activating protein regulation of actin cytoskeleton and hyphal polarity in Aspergillus nidulans

Recent advances in the characterization of ambient pH regulation of gene expression in filamentous fungi and yeasts

Receptor-independent Ambient pH signaling by ubiquitin attachment to fungal arrestin-like PalF.

Recognizing gene regulation by ambient pH

Refining the pH response in Aspergillus nidulans: a modulatory triad involving PacX, a novel zinc binuclear cluster protein

Regulation of gene expression by ambient pH in filamentous fungi and yeasts

Rescue of Aspergillus nidulans severely debilitating null mutations in ESCRT-0, I, II and III genes by inactivation of a salt-tolerance pathway allows examination of ESCRT gene roles in pH signalling

Searching for gold beyond mitosis: Mining intracellular membrane traffic in Aspergillus nidulans

Sequences of isopenicillin N synthetase genes suggest horizontal gene transfer from prokaryotes to eukaryotes

Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae

Specific DNA recognition by the Aspergillus nidulans three zinc finger transcription factor PacC.