Lista de obras -

4F2 (CD98) heavy chain is associated covalently with an amino acid transporter and controls intracellular trafficking and membrane topology of 4F2 heterodimer.

artículo científico publicado en 1999

A histone-like protein of mycobacteria possesses ferritin superfamily protein-like activity and protects against DNA damage by Fenton reaction.

artículo científico publicado en 2011

A murine thymic stromal cell line which may support the differentiation of CD4-8- thymocytes into CD4+8- alpha beta T cell receptor positive T cells

artículo científico publicado el 1 de julio de 1992

Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex

artículo científico publicado en 2000

Activation of nuclear factor-kappa B by linear ubiquitin chain assembly complex contributes to lung metastasis of osteosarcoma cells

artículo científico publicado en 2011

An ubiquitin ligase recognizing a protein oxidized by iron: implications for the turnover of oxidatively damaged proteins.

artículo científico publicado en 2003

Analysis of nuclear factor-κB (NF-κB) essential modulator (NEMO) binding to linear and lysine-linked ubiquitin chains and its role in the activation of NF-κB.

artículo científico publicado en 2012

Association of HPV infection with prognosis after neoadjuvant chemotherapy in advanced uterine cervical cancer

scientific article published on 01 July 2004

Chemoenzymatic ubiquitination of artificial substrates

artículo científico publicado en 2006

Cooperative Domain Formation by Homologous Motifs in HOIL-1L and SHARPIN Plays A Crucial Role in LUBAC Stabilization.

artículo científico publicado en 2018

Coordination of PGC-1beta and iron uptake in mitochondrial biogenesis and osteoclast activation

scientific journal article

Crucial Role of Linear Ubiquitin Chain Assembly Complex-Mediated Inhibition of Programmed Cell Death in TLR4-Mediated B Cell Responses and B1b Cell Development

artículo científico publicado en 2018

Crystal structure of the N-myristoylated lipopeptide-bound MHC class I complex.

artículo científico publicado en 2016

Crystallization and preliminary X-ray characterization of the Skp1-Fbg3 complex.

artículo científico

Defective immune responses in mice lacking LUBAC-mediated linear ubiquitination in B cells.

artículo científico publicado en 2013

Direct interactions between NEDD8 and ubiquitin E2 conjugating enzymes upregulate cullin-based E3 ligase activity.

artículo científico publicado en 2007

Discovery of linear ubiquitination, a crucial regulator for immune signaling and cell death

artículo científico publicado en 2020

Diverse roles of the ubiquitin system in NF-κB activation ⬇️

artículo científico publicado el 21 de marzo de 2013

Diverse ubiquitin signaling in NF-κB activation ⬇️

artículo científico publicado el 28 de abril de 2012

Expression of a constitutive mutant of iron regulatory protein 1 abolishes iron homeostasis in mammalian cells

artículo científico publicado en 1995

Functions of Linear Ubiquitin Chains in the NF-κB Pathway : Linear Polyubiquitin in NF-κB Signaling.

artículo científico publicado en 2010

Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis

artículo científico publicado en 2004

Gliotoxin suppresses NF-κB activation by selectively inhibiting linear ubiquitin chain assembly complex (LUBAC).

artículo científico publicado en 2014

Glycoprotein-specific ubiquitin ligases recognize N-glycans in unfolded substrates

scientific journal article

HIF and HOIL-1L-mediated PKCζ degradation stabilizes plasma membrane Na,K-ATPase to protect against hypoxia-induced lung injury

artículo científico publicado en 2017

HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains

artículo científico publicado en 2017

Heme induces ubiquitination and degradation of the transcription factor Bach1

artículo científico publicado en 2007

Heterogeneity in terms of interleukin 4-dependent regulation of Fc epsilon...receptor/CD23 expression on chronic B-lymphocytic leukemia cells

artículo científico publicado en 1989

IFN-γ or IFN-α ameliorates chronic proliferative dermatitis by inducing expression of linear ubiquitin chain assembly complex.

artículo científico publicado en 2014

IOP1 Protein Is an External Component of the Human Cytosolic Iron-Sulfur Cluster Assembly (CIA) Machinery and Functions in the MMS19 Protein-dependent CIA Pathway ⬇️

artículo científico publicado el 12 de abril de 2013

Identification of a conserved and functional iron-responsive element in the 5'-untranslated region of mammalian mitochondrial aconitase

scientific article published on 01 September 1996

Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2

artículo científico publicado en 2003

Identification, expression, and assay of an oxidation-specific ubiquitin ligase, HOIL-1.

artículo científico publicado en 2005

Immunoblot analysis of linear polyubiquitination of NEMO.

artículo científico publicado en 2015

In vitro induction of IgG anti-DNA antibody from high density B cells of systemic lupus erythematosus patients by an HLA DR-restricted T cell clone

scientific article published on 01 November 1992

Index markers of chronic fatigue syndrome with dysfunction of TCA and urea cycles.

artículo científico publicado en 2016

Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: Implications for degradation of oxidized proteins ⬇️

artículo científico publicado el 28 de abril de 1998

Iron-induced dissociation of the Aft1p transcriptional regulator from target gene promoters is an initial event in iron-dependent gene suppression.

artículo científico publicado en 2012

LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis.

artículo científico publicado en 2015

LUBAC controls chromosome alignment by targeting CENP-E to attached kinetochores

scientific article published in Nature Communications

LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMO ⬇️

artículo científico publicado el 2 de agosto de 2011

LUBAC, a novel ubiquitin ligase for linear ubiquitination, is crucial for inflammation and immune responses.

artículo científico

Linear Ubiquitin Assembly Complex Negatively Regulates RIG-I- and TRIM25-Mediated Type I Interferon Induction ⬇️

artículo científico publicado el 4 de febrero de 2011

Linear polyubiquitin chains: a new modifier involved in NFκB activation and chronic inflammation, including dermatitis.

artículo científico publicado en 2011

Linear polyubiquitination: a new regulator of NF-kappaB activation.

scientific article published on 19 June 2009

Linear ubiquitin chains: NF-κB signalling, cell death and beyond.

artículo científico publicado en 2014

Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis.

artículo científico publicado en 2016

Linear ubiquitination: A novel NF-κB regulatory mechanism for inflammatory and immune responses by the LUBAC ubiquitin ligase complex [Review] ⬇️

artículo científico publicado el 19 de mayo de 2012

MDM2 is a novel E3 ligase for HIV-1 Vif.

artículo científico publicado en 2009

Mitogen-inducible SIPA1 is mapped to the conserved syntenic groups of chromosome 19 in mouse and chromosome 11q13.3 centromeric to BCL1 in human.

artículo científico publicado en 1997

Modulation of autoimmune pathogenesis by T cell-triggered inflammatory cell death

scientific article published on 28 August 2019

Multiple roles of Rbx1 in the VBC-Cul2 ubiquitin ligase complex.

artículo científico publicado en 2005

Mutual regulation of conventional protein kinase C and a ubiquitin ligase complex.

artículo científico publicado en 2006

Myeloproliferative stem cell disorders by deregulated Rap1 activation in SPA-1-deficient mice

artículo científico publicado en 2003

NEDD8 recruits E2-ubiquitin to SCF E3 ligase.

artículo científico publicado en 2001

NMR resonance assignments of the NZF domain of mouse HOIL-1L free and bound to linear di-ubiquitin

artículo científico publicado en 2018

Novel translational control through an iron-responsive element by interaction of multifunctional protein YB-1 and IRP2.

artículo científico publicado en 2002

Pathological Endogenous α-Synuclein Accumulation in Oligodendrocyte Precursor Cells Potentially Induces Inclusions in Multiple System Atrophy.

artículo científico publicado en 2017

Possible involvement of iron-induced oxidative insults in neurodegeneration.

artículo científico publicado en 2014

Posttranslational Modification of HOIP Blocks Toll-Like Receptor 4-Mediated Linear-Ubiquitin-Chain Formation

artículo científico publicado en 2015

Potential biomarkers of fatigue identified by plasma metabolome analysis in rats

artículo científico publicado en 2015

Protein oxidation mediated by heme-induced active site conversion specific for heme-regulated transcription factor, iron response regulator

artículo científico publicado en 2016

RPAP3 enhances cytotoxicity of doxorubicin by impairing NF-kappa B pathway.

artículo científico publicado en 2010

Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin.

artículo científico publicado en 2013

Redox-Dependent Dynamics in Heme-Bound Bacterial Iron Response Regulator (Irr) Protein

artículo científico publicado en 2016

Redox-dependent axial ligand replacement and its functional significance in heme-bound iron regulatory proteins.

artículo científico publicado en 2018

Regulation of cellular iron metabolism: Iron-dependent degradation of IRP by SCFFBXL5 ubiquitin ligase

scientific article published on 13 September 2018

Requirements for iron-regulated degradation of the RNA binding protein, iron regulatory protein 2

artículo científico publicado en 1995

Roles of linear ubiquitinylation, a crucial regulator of NF-κB and cell death, in the immune system

artículo científico

Roles of the NF-κB Pathway in B-Lymphocyte Biology.

artículo científico

SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex

artículo científico publicado en 2011

Specific heme binding to heme regulatory motifs in iron regulatory proteins and its functional significance

artículo científico publicado en 2019

Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation

artículo científico publicado en 2012

Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex

artículo científico publicado en 2011

Stabilization of iron regulatory protein 2, IRP2, by aluminum

artículo científico publicado en 1999

Structural basis for distinct roles of Lys63- and Lys48-linked polyubiquitin chains.

artículo científico publicado en 2004

Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN

artículo científico publicado en 2014

Synthesis and Analysis of Linear Ubiquitin Chains ⬇️

artículo científico publicado el 1 de enero de 2012

Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice

scientific journal article

The E3 ubiquitin ligase HOIL-1 induces the polyubiquitination and degradation of SOCS6 associated proteins

artículo científico publicado en 2006

The FBXL5-IRP2 axis is integral to control of iron metabolism in vivo

scientific journal article

The HOIL-1L ligase modulates immune signalling and cell death via monoubiquitination of LUBAC

scientific article published on 11 May 2020

The Structural Differences between a Glycoprotein Specific F-Box Protein Fbs1 and Its Homologous Protein FBG3.

artículo científico publicado en 2015

The bacterial effector Cif interferes with SCF ubiquitin ligase function by inhibiting deneddylation of Cullin1 ⬇️

artículo científico publicado el 17 de septiembre de 2010

The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation.

artículo científico publicado en 2014

The unexpected role of polyubiquitin chains in the formation of fibrillar aggregates.

artículo científico publicado en 2015

Two coordinated mechanisms underlie tumor necrosis factor alpha-induced immediate and delayed IκB kinase activation.

artículo científico publicado en 2013

Ubiquitin chain elongation: an intriguing strategy.

artículo científico publicado en 2014

Ubiquitin is degraded by the ubiquitin system as a monomer and as part of its conjugated target.

artículo científico publicado en 2007

Ubiquitination of APOBEC3 proteins by the Vif-Cullin5-ElonginB-ElonginC complex.

artículo científico publicado en 2005

Ubiquitination of exposed glycoproteins by SCFFBXO27 directs damaged lysosomes for autophagy.

artículo científico publicado en 2017

Unusual heme binding in the bacterial iron response regulator protein: spectral characterization of heme binding to the heme regulatory motif

artículo científico publicado en 2011

[Recent advance in the understanding of iron metabolism and its role on host defense]

scientific article published on 01 December 2005

Lista de obras de

4F2 (CD98) heavy chain is associated covalently with an amino acid transporter and controls intracellular trafficking and membrane topology of 4F2 heterodimer.

A histone-like protein of mycobacteria possesses ferritin superfamily protein-like activity and protects against DNA damage by Fenton reaction.

A murine thymic stromal cell line which may support the differentiation of CD4-8- thymocytes into CD4+8- alpha beta T cell receptor positive T cells

Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex

Activation of nuclear factor-kappa B by linear ubiquitin chain assembly complex contributes to lung metastasis of osteosarcoma cells

An ubiquitin ligase recognizing a protein oxidized by iron: implications for the turnover of oxidatively damaged proteins.

Analysis of nuclear factor-κB (NF-κB) essential modulator (NEMO) binding to linear and lysine-linked ubiquitin chains and its role in the activation of NF-κB.

Association of HPV infection with prognosis after neoadjuvant chemotherapy in advanced uterine cervical cancer

Chemoenzymatic ubiquitination of artificial substrates

Cooperative Domain Formation by Homologous Motifs in HOIL-1L and SHARPIN Plays A Crucial Role in LUBAC Stabilization.

Coordination of PGC-1beta and iron uptake in mitochondrial biogenesis and osteoclast activation

Crucial Role of Linear Ubiquitin Chain Assembly Complex-Mediated Inhibition of Programmed Cell Death in TLR4-Mediated B Cell Responses and B1b Cell Development

Crystal structure of the N-myristoylated lipopeptide-bound MHC class I complex.

Crystallization and preliminary X-ray characterization of the Skp1-Fbg3 complex.

Defective immune responses in mice lacking LUBAC-mediated linear ubiquitination in B cells.

Direct interactions between NEDD8 and ubiquitin E2 conjugating enzymes upregulate cullin-based E3 ligase activity.

Discovery of linear ubiquitination, a crucial regulator for immune signaling and cell death

Diverse roles of the ubiquitin system in NF-κB activation ⬇️

Diverse ubiquitin signaling in NF-κB activation ⬇️

Expression of a constitutive mutant of iron regulatory protein 1 abolishes iron homeostasis in mammalian cells

Functions of Linear Ubiquitin Chains in the NF-κB Pathway : Linear Polyubiquitin in NF-κB Signaling.

Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis

Gliotoxin suppresses NF-κB activation by selectively inhibiting linear ubiquitin chain assembly complex (LUBAC).

Glycoprotein-specific ubiquitin ligases recognize N-glycans in unfolded substrates

HIF and HOIL-1L-mediated PKCζ degradation stabilizes plasma membrane Na,K-ATPase to protect against hypoxia-induced lung injury

HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains

Heme induces ubiquitination and degradation of the transcription factor Bach1

Heterogeneity in terms of interleukin 4-dependent regulation of Fc epsilon...receptor/CD23 expression on chronic B-lymphocytic leukemia cells

IFN-γ or IFN-α ameliorates chronic proliferative dermatitis by inducing expression of linear ubiquitin chain assembly complex.

IOP1 Protein Is an External Component of the Human Cytosolic Iron-Sulfur Cluster Assembly (CIA) Machinery and Functions in the MMS19 Protein-dependent CIA Pathway ⬇️

Identification of a conserved and functional iron-responsive element in the 5'-untranslated region of mammalian mitochondrial aconitase

Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2

Identification, expression, and assay of an oxidation-specific ubiquitin ligase, HOIL-1.

Immunoblot analysis of linear polyubiquitination of NEMO.

In vitro induction of IgG anti-DNA antibody from high density B cells of systemic lupus erythematosus patients by an HLA DR-restricted T cell clone

Index markers of chronic fatigue syndrome with dysfunction of TCA and urea cycles.

Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: Implications for degradation of oxidized proteins ⬇️

Iron-induced dissociation of the Aft1p transcriptional regulator from target gene promoters is an initial event in iron-dependent gene suppression.

LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis.

LUBAC controls chromosome alignment by targeting CENP-E to attached kinetochores

LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMO ⬇️

LUBAC, a novel ubiquitin ligase for linear ubiquitination, is crucial for inflammation and immune responses.

Linear Ubiquitin Assembly Complex Negatively Regulates RIG-I- and TRIM25-Mediated Type I Interferon Induction ⬇️

Linear polyubiquitin chains: a new modifier involved in NFκB activation and chronic inflammation, including dermatitis.

Linear polyubiquitination: a new regulator of NF-kappaB activation.

Linear ubiquitin chains: NF-κB signalling, cell death and beyond.

Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis.

Linear ubiquitination: A novel NF-κB regulatory mechanism for inflammatory and immune responses by the LUBAC ubiquitin ligase complex [Review] ⬇️

MDM2 is a novel E3 ligase for HIV-1 Vif.

Mitogen-inducible SIPA1 is mapped to the conserved syntenic groups of chromosome 19 in mouse and chromosome 11q13.3 centromeric to BCL1 in human.

Modulation of autoimmune pathogenesis by T cell-triggered inflammatory cell death

Multiple roles of Rbx1 in the VBC-Cul2 ubiquitin ligase complex.

Mutual regulation of conventional protein kinase C and a ubiquitin ligase complex.

Myeloproliferative stem cell disorders by deregulated Rap1 activation in SPA-1-deficient mice

NEDD8 recruits E2-ubiquitin to SCF E3 ligase.

NMR resonance assignments of the NZF domain of mouse HOIL-1L free and bound to linear di-ubiquitin

Novel translational control through an iron-responsive element by interaction of multifunctional protein YB-1 and IRP2.

Pathological Endogenous α-Synuclein Accumulation in Oligodendrocyte Precursor Cells Potentially Induces Inclusions in Multiple System Atrophy.

Possible involvement of iron-induced oxidative insults in neurodegeneration.

Posttranslational Modification of HOIP Blocks Toll-Like Receptor 4-Mediated Linear-Ubiquitin-Chain Formation

Potential biomarkers of fatigue identified by plasma metabolome analysis in rats

Protein oxidation mediated by heme-induced active site conversion specific for heme-regulated transcription factor, iron response regulator

RPAP3 enhances cytotoxicity of doxorubicin by impairing NF-kappa B pathway.

Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin.

Redox-Dependent Dynamics in Heme-Bound Bacterial Iron Response Regulator (Irr) Protein

Redox-dependent axial ligand replacement and its functional significance in heme-bound iron regulatory proteins.

Regulation of cellular iron metabolism: Iron-dependent degradation of IRP by SCFFBXL5 ubiquitin ligase

Requirements for iron-regulated degradation of the RNA binding protein, iron regulatory protein 2

Roles of linear ubiquitinylation, a crucial regulator of NF-κB and cell death, in the immune system

Roles of the NF-κB Pathway in B-Lymphocyte Biology.

SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex

Specific heme binding to heme regulatory motifs in iron regulatory proteins and its functional significance

Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation

Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex

Stabilization of iron regulatory protein 2, IRP2, by aluminum

Structural basis for distinct roles of Lys63- and Lys48-linked polyubiquitin chains.

Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN

Synthesis and Analysis of Linear Ubiquitin Chains ⬇️

Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice