Lista de obras - Olof Rådmark - Dominio Público Uruguay

1-Oleoyl-2-acetylglycerol stimulates 5-lipoxygenase activity via a putative (phospho)lipid binding site within the N-terminal C2-like domain

artículo científico publicado en 2005

12/15-lipoxygenase-derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases

artículo científico publicado en 2010

5-Lipoxygenase activation by MAPKAPK-2 and ERKs.

artículo científico publicado en 2003

5-Lipoxygenase, a key enzyme for leukotriene biosynthesis in health and disease

artículo científico publicado en 2015

5-Lipoxygenase: mechanisms of regulation

artículo científico publicado en 2008

5-Lipoxygenase: regulation of expression and enzyme activity

artículo científico publicado en 2007

5-lipoxygenase-derived leukotrienes: mediators also of atherosclerotic inflammation

artículo científico publicado en 2003

5-lipoxygenase: regulation and possible involvement in atherosclerosis

artículo científico publicado en 2007

A mutation interfering with 5-lipoxygenase domain interaction leads to increased enzyme activity.

artículo científico publicado en 2014

Activated LTB4 pathway in muscle tissue of patients with polymyositis or dermatomyositis.

artículo científico publicado en 2012

Activation of 5-lipoxygenase by cell stress is calcium independent in human polymorphonuclear leukocytes

artículo científico publicado en 2002

Analysis of the 5-lipoxygenase promoter and characterization of a vitamin D receptor binding site

artículo científico publicado en 2006

Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males

artículo científico publicado en 2017

Arachidonate 5-lipoxygenase

artículo científico publicado en 2002

Arachidonic acid promotes phosphorylation of 5-lipoxygenase at Ser-271 by MAPK-activated protein kinase 2 (MK2).

artículo científico publicado en 2002

C-terminus of p47(phox) is required for interaction with leukocyte type rat 12-lipoxygenase

artículo científico publicado en 2005

Calcitriol upregulates open chromatin and elongation markers at functional vitamin D response elements in the distal part of the 5-lipoxygenase gene

artículo científico

Calcium binding to 5-lipoxygenase

artículo científico publicado en 2002

Caspase-mediated degradation of human 5-lipoxygenase in B lymphocytic cells

artículo científico publicado en 2005

Cell type-dependent activation of 5-lipoxygenase by arachidonic acid

artículo científico publicado en 2003

Cloning of rat p47phox and comparison with human p47phox

scientific journal article

Coactosin-like protein functions as a stabilizing chaperone for 5-lipoxygenase: role of tryptophan 102.

artículo científico publicado en 2009

Coactosin-like protein supports 5-lipoxygenase enzyme activity and up-regulates leukotriene A4 production

artículo científico publicado en 2006

ERK-mediated regulation of leukotriene biosynthesis by androgens: a molecular basis for gender differences in inflammation and asthma

scholarly article

Exosomes from human macrophages and dendritic cells contain enzymes for leukotriene biosynthesis and promote granulocyte migration

artículo científico publicado en 2010

Expression of 5-lipoxygenase and 15-lipoxygenase in rheumatoid arthritis synovium and effects of intraarticular glucocorticoids

artículo científico publicado en 2009

Extracellular signal-regulated kinases phosphorylate 5-lipoxygenase and stimulate 5-lipoxygenase product formation in leukocytes

artículo científico publicado en 2002

Functional characterization of vitamin D responding regions in the human 5-Lipoxygenase gene

artículo científico publicado en 2007

GC-rich sequences in the 5-lipoxygenase gene promoter are required for expression in Mono Mac 6 cells, characterization of a novel Sp1 binding site

artículo científico publicado en 2005

Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death

artículo científico publicado en 2008

Human Dicer C-terminus functions as a 5-lipoxygenase binding domain

artículo científico publicado en 2008

Hyperforin is a novel type of 5-lipoxygenase inhibitor with high efficacy in vivo.

artículo científico publicado en 2009

Hypertonicity suppresses ionophore-induced product formation and translocation of 5-lipoxygenase in human leukocytes

artículo científico publicado en 2002

In vivo sex differences in leukotriene biosynthesis in zymosan-induced peritonitis

artículo científico publicado en 2014

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

artículo científico publicado en 2014

Lipoxin and resolvin biosynthesis is dependent on 5-lipoxygenase activating protein

artículo científico publicado en 2015

Microsomal prostaglandin E synthase 1 determines tumor growth in vivo of prostate and lung cancer cells

artículo científico publicado en 2009

Modulation of leukotriene signaling inhibiting cell growth in chronic myeloid leukemia

artículo científico publicado en 2016

Molecular cloning and functional characterization of mouse coactosin-like protein

artículo científico publicado en 2002

Monocyte-derived soluble protein confers 5-lipoxygenase activity Ca2+-dependent

artículo científico publicado en 2002

Mutation analysis of the human 5-lipoxygenase C-terminus: support for a stabilizing C-terminal loop

artículo científico publicado en 2005

NMR structure of human coactosin-like protein.

artículo científico publicado en 2004

Necrosis in DU145 prostate cancer spheroids induces COX-2/mPGES-1-derived PGE2 to promote tumor growth and to inhibit T cell activation

artículo científico publicado en 2013

Novel oxylipins formed from docosahexaenoic acid by potato lipoxygenase--10(S)-hydroxydocosahexaenoic acid and 10,20-dihydroxydocosahexaenoic acid

artículo científico publicado en 2005

Phosphorylation of serine 523 on 5-lipoxygenase in human B lymphocytes

artículo científico publicado en 2015

Phosphorylation- and stimulus-dependent inhibition of cellular 5-lipoxygenase activity by nonredox-type inhibitors

artículo científico publicado en 2003

Pulmonary epithelial cancer cells and their exosomes metabolize myeloid cell-derived leukotriene C4 to leukotriene D4.

artículo científico publicado en 2016

Pulmonary sarcoidosis is associated with exosomal vitamin D-binding protein and inflammatory molecules

artículo científico publicado en 2016

Regulation of 5-lipoxygenase enzyme activity

artículo científico publicado en 2005

Regulation of the activity of 5-lipoxygenase, a key enzyme in leukotriene biosynthesis

artículo científico publicado en 2010

Ribonuclease activity and RNA binding of recombinant human Dicer

artículo científico publicado en 2002

Role of DNA methylation and methyl-DNA binding proteins in the repression of 5-lipoxygenase promoter activity

artículo científico publicado en 2009

Roles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesis

artículo científico publicado en 2014

Stabilisation and characterisation of the isolated regulatory domain of human 5-lipoxygenase

scholarly article by Mirjam Schröder published in October 2014

Structural and Functional Analysis of Calcium Ion Mediated Binding of 5-Lipoxygenase to Nanodiscs

artículo científico publicado en 2016

Testosterone suppresses phospholipase D, causing sex differences in leukotriene biosynthesis in human monocytes ⬇️

artículo científico publicado el 21 de junio de 2011

The C2-like beta-barrel domain mediates the Ca2+-dependent resistance of 5-lipoxygenase activity against inhibition by glutathione peroxidase-1.

artículo científico publicado en 2003

The histone deacetylase inhibitor trichostatin A mediates upregulation of 5-lipoxygenase promoter activity by recruitment of Sp1 to distinct GC-boxes

artículo científico publicado en 2007

The nuclear RNase III Drosha initiates microRNA processing

artículo científico publicado en 2003

Thr94 in bovine myelin basic protein is a second phosphorylation site for 42-kDa mitogen-activated protein kinase (ERK2).

artículo científico publicado en 2003

Time-resolved in situ assembly of the leukotriene-synthetic 5-lipoxygenase/5-lipoxygenase-activating protein complex in blood leukocytes

artículo científico publicado en 2015

Zymosan suppresses leukotriene C₄ synthase activity in differentiating monocytes: antagonism by aspirin and protein kinase inhibitors

artículo científico publicado en 2011

Lista de obras de Olof Rådmark

1-Oleoyl-2-acetylglycerol stimulates 5-lipoxygenase activity via a putative (phospho)lipid binding site within the N-terminal C2-like domain

12/15-lipoxygenase-derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases

5-Lipoxygenase activation by MAPKAPK-2 and ERKs.

5-Lipoxygenase, a key enzyme for leukotriene biosynthesis in health and disease

5-Lipoxygenase: mechanisms of regulation

5-Lipoxygenase: regulation of expression and enzyme activity

5-lipoxygenase-derived leukotrienes: mediators also of atherosclerotic inflammation

5-lipoxygenase: regulation and possible involvement in atherosclerosis

A mutation interfering with 5-lipoxygenase domain interaction leads to increased enzyme activity.

Activated LTB4 pathway in muscle tissue of patients with polymyositis or dermatomyositis.

Activation of 5-lipoxygenase by cell stress is calcium independent in human polymorphonuclear leukocytes

Analysis of the 5-lipoxygenase promoter and characterization of a vitamin D receptor binding site

Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males

Arachidonate 5-lipoxygenase

Arachidonic acid promotes phosphorylation of 5-lipoxygenase at Ser-271 by MAPK-activated protein kinase 2 (MK2).

C-terminus of p47(phox) is required for interaction with leukocyte type rat 12-lipoxygenase

Calcitriol upregulates open chromatin and elongation markers at functional vitamin D response elements in the distal part of the 5-lipoxygenase gene

Calcium binding to 5-lipoxygenase

Caspase-mediated degradation of human 5-lipoxygenase in B lymphocytic cells

Cell type-dependent activation of 5-lipoxygenase by arachidonic acid

Cloning of rat p47phox and comparison with human p47phox

Coactosin-like protein functions as a stabilizing chaperone for 5-lipoxygenase: role of tryptophan 102.

Coactosin-like protein supports 5-lipoxygenase enzyme activity and up-regulates leukotriene A4 production

ERK-mediated regulation of leukotriene biosynthesis by androgens: a molecular basis for gender differences in inflammation and asthma

Exosomes from human macrophages and dendritic cells contain enzymes for leukotriene biosynthesis and promote granulocyte migration

Expression of 5-lipoxygenase and 15-lipoxygenase in rheumatoid arthritis synovium and effects of intraarticular glucocorticoids

Extracellular signal-regulated kinases phosphorylate 5-lipoxygenase and stimulate 5-lipoxygenase product formation in leukocytes

Functional characterization of vitamin D responding regions in the human 5-Lipoxygenase gene

GC-rich sequences in the 5-lipoxygenase gene promoter are required for expression in Mono Mac 6 cells, characterization of a novel Sp1 binding site

Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death

Human Dicer C-terminus functions as a 5-lipoxygenase binding domain

Hyperforin is a novel type of 5-lipoxygenase inhibitor with high efficacy in vivo.

Hypertonicity suppresses ionophore-induced product formation and translocation of 5-lipoxygenase in human leukocytes

In vivo sex differences in leukotriene biosynthesis in zymosan-induced peritonitis

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

Lipoxin and resolvin biosynthesis is dependent on 5-lipoxygenase activating protein

Microsomal prostaglandin E synthase 1 determines tumor growth in vivo of prostate and lung cancer cells

Modulation of leukotriene signaling inhibiting cell growth in chronic myeloid leukemia

Molecular cloning and functional characterization of mouse coactosin-like protein

Monocyte-derived soluble protein confers 5-lipoxygenase activity Ca2+-dependent

Mutation analysis of the human 5-lipoxygenase C-terminus: support for a stabilizing C-terminal loop

NMR structure of human coactosin-like protein.

Necrosis in DU145 prostate cancer spheroids induces COX-2/mPGES-1-derived PGE2 to promote tumor growth and to inhibit T cell activation

Novel oxylipins formed from docosahexaenoic acid by potato lipoxygenase--10(S)-hydroxydocosahexaenoic acid and 10,20-dihydroxydocosahexaenoic acid

Phosphorylation of serine 523 on 5-lipoxygenase in human B lymphocytes

Phosphorylation- and stimulus-dependent inhibition of cellular 5-lipoxygenase activity by nonredox-type inhibitors

Pulmonary epithelial cancer cells and their exosomes metabolize myeloid cell-derived leukotriene C4 to leukotriene D4.

Pulmonary sarcoidosis is associated with exosomal vitamin D-binding protein and inflammatory molecules

Regulation of 5-lipoxygenase enzyme activity

Regulation of the activity of 5-lipoxygenase, a key enzyme in leukotriene biosynthesis

Ribonuclease activity and RNA binding of recombinant human Dicer

Role of DNA methylation and methyl-DNA binding proteins in the repression of 5-lipoxygenase promoter activity

Roles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesis

Stabilisation and characterisation of the isolated regulatory domain of human 5-lipoxygenase

Structural and Functional Analysis of Calcium Ion Mediated Binding of 5-Lipoxygenase to Nanodiscs

Testosterone suppresses phospholipase D, causing sex differences in leukotriene biosynthesis in human monocytes ⬇️

The C2-like beta-barrel domain mediates the Ca2+-dependent resistance of 5-lipoxygenase activity against inhibition by glutathione peroxidase-1.

The histone deacetylase inhibitor trichostatin A mediates upregulation of 5-lipoxygenase promoter activity by recruitment of Sp1 to distinct GC-boxes

The nuclear RNase III Drosha initiates microRNA processing

Thr94 in bovine myelin basic protein is a second phosphorylation site for 42-kDa mitogen-activated protein kinase (ERK2).

Time-resolved in situ assembly of the leukotriene-synthetic 5-lipoxygenase/5-lipoxygenase-activating protein complex in blood leukocytes

Zymosan suppresses leukotriene C₄ synthase activity in differentiating monocytes: antagonism by aspirin and protein kinase inhibitors