Lista de obras -

A molecular biology and phase II trial of lapatinib in children with refractory CNS malignancies: a pediatric brain tumor consortium study

artículo científico publicado en 2013

A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat

artículo científico publicado en 2011

A pediatric phase 1 trial of vorinostat and temozolomide in relapsed or refractory primary brain or spinal cord tumors: a Children's Oncology Group phase 1 consortium study

artículo científico publicado en 2013

A perivascular niche for brain tumor stem cells

artículo científico publicado en 2007

A phase 1 and pharmacokinetic study of enzastaurin in pediatric patients with refractory primary central nervous system tumors: a pediatric brain tumor consortium study

artículo científico publicado en 2014

A phase I and biology study of gefitinib and radiation in children with newly diagnosed brain stem gliomas or supratentorial malignant gliomas

artículo científico publicado en 2010

A pilot study of risk-adapted radiotherapy and chemotherapy in patients with supratentorial PNET.

artículo científico publicado en 2008

A prognostic gene expression signature in infratentorial ependymoma

artículo científico publicado en 2012

Advances and Challenges in Pediatric and Childhood Cancers

artículo científico publicado en 2020

An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes.

artículo científico publicado en 2015

Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data

artículo científico publicado en 2012

Atypical teratoid/rhabdoid tumors (ATRT): improved survival in children 3 years of age and older with radiation therapy and high-dose alkylator-based chemotherapy

artículo científico publicado en 2005

Bevacizumab (BVZ)-associated toxicities in children with recurrent central nervous system tumors treated with BVZ and irinotecan (CPT-11): a Pediatric Brain Tumor Consortium Study (PBTC-022).

artículo científico publicado en 2013

C11orf95-RELA fusions drive oncogenic NF-κB signalling in ependymoma

artículo científico publicado en 2014

Challenges to curing primary brain tumours

scientific article published on 01 August 2019

Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion–Positive Supratentorial Ependymomas

artículo científico publicado en 2021

Cross-species genomics matches driver mutations and cell compartments to model ependymoma

artículo científico publicado en 2010

Defining future directions in spinal cord tumor research: proceedings from the National Institutes of Health workshop

artículo científico publicado en 2010

EP-03MOLECULAR CLASSIFICATION OF EPENDYMAL TUMORS ACROSS ALL CNS COMPARTMENTS, HISTOPATHOLOGICAL GRADES AND AGE GROUPS.

artículo científico publicado en 2015

ERBB receptor signaling promotes ependymoma cell proliferation and represents a potential novel therapeutic target for this disease.

artículo científico publicado en 2002

Efficacy of bevacizumab plus irinotecan in children with recurrent low-grade gliomas--a Pediatric Brain Tumor Consortium study

artículo científico publicado en 2013

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma

artículo científico publicado en 2014

Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling

artículo científico publicado en 2004

Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome

artículo científico publicado en 2011

Lack of efficacy of bevacizumab + irinotecan in cases of pediatric recurrent ependymoma--a Pediatric Brain Tumor Consortium study

artículo científico publicado en 2012

Lack of efficacy of bevacizumab plus irinotecan in children with recurrent malignant glioma and diffuse brainstem glioma: a Pediatric Brain Tumor Consortium study

artículo científico publicado en 2010

MBCL-44. THE MOLECULAR AND CLINICAL LANDSCAPE OF INFANT MEDULLOBLASTOMA (iMB): RESULTS AND MOLECULAR ANALYSIS FROM A PROSPECTIVE, MULTICENTER PHASE II TRIAL (SJYC07)

MPTH-26MOLECULAR REFINEMENT OF PEDIATRIC POSTERIOR FOSSA EPENDYMOMA.

artículo científico publicado en 2015

Mapping cancer origins

artículo científico publicado en 2011

Medulloblastoma Sensitivity to 17-Allylamino-17-demethoxygeldanamycin Requires MEK/ERK ⬇️

artículo científico publicado el 22 de abril de 2003

Medulloblastomics: the end of the beginning

scientific article published on December 2012

Mitotic percentage index: a new prognostic factor for childhood medulloblastoma ⬇️

artículo científico publicado el 1 de abril de 1997

Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups

artículo científico publicado en 2015

Molecular characterization of choroid plexus tumors reveals novel clinically relevant subgroups

artículo científico publicado en 2014

Molecular characterization of the pediatric preclinical testing panel

artículo científico publicado en 2008

Molecular insights into pediatric brain tumors have the potential to transform therapy

artículo científico publicado en 2014

Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

artículo científico publicado en 2012

Molecular subgroups of medulloblastoma: the current consensus

artículo científico publicado en 2012

Multifactorial analysis of predictors of outcome in pediatric intracranial ependymoma

artículo científico publicado en 2008

Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

artículo científico publicado en 2009

Myc and Loss of p53 Cooperate to Drive Formation of Choroid Plexus Carcinoma

scientific article published on 18 March 2019

Novel mutations target distinct subgroups of medulloblastoma.

artículo científico publicado en 2012

Outcomes by Clinical and Molecular Features in Children With Medulloblastoma Treated With Risk-Adapted Therapy: Results of an International Phase III Trial (SJMB03)

artículo científico publicado en 2021

PDGFRB is overexpressed in metastatic medulloblastoma ⬇️

artículo científico publicado el 1 de noviembre de 2003

Pediatric phase I trial and pharmacokinetic study of vorinostat: a Children's Oncology Group phase I consortium report

artículo científico publicado en 2010

Phase I study of 5-fluorouracil in children and young adults with recurrent ependymoma

artículo científico publicado en 2015

Phase I study of temsirolimus in pediatric patients with recurrent/refractory solid tumors

artículo científico publicado en 2011

Phase I study of vandetanib during and after radiotherapy in children with diffuse intrinsic pontine glioma

artículo científico publicado en 2010

Phase I trial of MK-0752 in children with refractory CNS malignancies: a pediatric brain tumor consortium study

artículo científico publicado en 2011

Phase I trial of lapatinib in children with refractory CNS malignancies: a Pediatric Brain Tumor Consortium study

artículo científico publicado en 2010

Phase I trial of weekly MK-0752 in children with refractory central nervous system malignancies: a pediatric brain tumor consortium study

artículo científico publicado en 2015

Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation

artículo científico publicado en 2008

Pten deletion causes mTorc1-dependent ectopic neuroblast differentiation without causing uniform migration defects

artículo científico publicado en 2012

Radial glia cells are candidate stem cells of ependymoma

artículo científico publicado en 2005

Rapid diagnosis of medulloblastoma molecular subgroups

artículo científico publicado en 2011

Reply to 'Assembling the brain trust: the multidisciplinary imperative in neuro-oncology'

artículo científico publicado en 2019

Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial

artículo científico publicado en 2006

Risk-adapted therapy for young children with medulloblastoma (SJYC07): therapeutic and molecular outcomes from a multicentre, phase 2 trial

scientific article published on 16 May 2018

Siah regulation of Pard3A controls neuronal cell adhesion during germinal zone exit

artículo científico publicado en 2010

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

artículo científico publicado en 2012

Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.

artículo científico publicado en 2018

Subtypes of medulloblastoma have distinct developmental origins

artículo científico publicado en 2010

The G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog-driven medulloblastoma

artículo científico publicado en 2014

The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants

artículo científico publicado en 2016

The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes.

artículo científico publicado en 2014

The miR-17~92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma

artículo científico publicado en 2009

The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation

artículo científico publicado en 2005

Vismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog-Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032.

artículo científico publicado en 2015

What's new in neuro-oncology? Recent advances in medulloblastoma ⬇️

artículo científico publicado el 1 de enero de 2003

Lista de obras de

A molecular biology and phase II trial of lapatinib in children with refractory CNS malignancies: a pediatric brain tumor consortium study

A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat

A pediatric phase 1 trial of vorinostat and temozolomide in relapsed or refractory primary brain or spinal cord tumors: a Children's Oncology Group phase 1 consortium study

A perivascular niche for brain tumor stem cells

A phase 1 and pharmacokinetic study of enzastaurin in pediatric patients with refractory primary central nervous system tumors: a pediatric brain tumor consortium study

A phase I and biology study of gefitinib and radiation in children with newly diagnosed brain stem gliomas or supratentorial malignant gliomas

A pilot study of risk-adapted radiotherapy and chemotherapy in patients with supratentorial PNET.

A prognostic gene expression signature in infratentorial ependymoma

Advances and Challenges in Pediatric and Childhood Cancers

An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes.

Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data

Atypical teratoid/rhabdoid tumors (ATRT): improved survival in children 3 years of age and older with radiation therapy and high-dose alkylator-based chemotherapy

Bevacizumab (BVZ)-associated toxicities in children with recurrent central nervous system tumors treated with BVZ and irinotecan (CPT-11): a Pediatric Brain Tumor Consortium Study (PBTC-022).

C11orf95-RELA fusions drive oncogenic NF-κB signalling in ependymoma

Challenges to curing primary brain tumours

Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion–Positive Supratentorial Ependymomas

Cross-species genomics matches driver mutations and cell compartments to model ependymoma

Defining future directions in spinal cord tumor research: proceedings from the National Institutes of Health workshop

EP-03MOLECULAR CLASSIFICATION OF EPENDYMAL TUMORS ACROSS ALL CNS COMPARTMENTS, HISTOPATHOLOGICAL GRADES AND AGE GROUPS.

ERBB receptor signaling promotes ependymoma cell proliferation and represents a potential novel therapeutic target for this disease.

Efficacy of bevacizumab plus irinotecan in children with recurrent low-grade gliomas--a Pediatric Brain Tumor Consortium study

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma

Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling

Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome

Lack of efficacy of bevacizumab + irinotecan in cases of pediatric recurrent ependymoma--a Pediatric Brain Tumor Consortium study

Lack of efficacy of bevacizumab plus irinotecan in children with recurrent malignant glioma and diffuse brainstem glioma: a Pediatric Brain Tumor Consortium study

MBCL-44. THE MOLECULAR AND CLINICAL LANDSCAPE OF INFANT MEDULLOBLASTOMA (iMB): RESULTS AND MOLECULAR ANALYSIS FROM A PROSPECTIVE, MULTICENTER PHASE II TRIAL (SJYC07)

MPTH-26MOLECULAR REFINEMENT OF PEDIATRIC POSTERIOR FOSSA EPENDYMOMA.

Mapping cancer origins

Medulloblastoma Sensitivity to 17-Allylamino-17-demethoxygeldanamycin Requires MEK/ERK ⬇️

Medulloblastomics: the end of the beginning

Mitotic percentage index: a new prognostic factor for childhood medulloblastoma ⬇️

Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups

Molecular characterization of choroid plexus tumors reveals novel clinically relevant subgroups

Molecular characterization of the pediatric preclinical testing panel

Molecular insights into pediatric brain tumors have the potential to transform therapy

Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

Molecular subgroups of medulloblastoma: the current consensus

Multifactorial analysis of predictors of outcome in pediatric intracranial ependymoma

Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

Myc and Loss of p53 Cooperate to Drive Formation of Choroid Plexus Carcinoma

Novel mutations target distinct subgroups of medulloblastoma.

Outcomes by Clinical and Molecular Features in Children With Medulloblastoma Treated With Risk-Adapted Therapy: Results of an International Phase III Trial (SJMB03)

PDGFRB is overexpressed in metastatic medulloblastoma ⬇️

Pediatric phase I trial and pharmacokinetic study of vorinostat: a Children's Oncology Group phase I consortium report

Phase I study of 5-fluorouracil in children and young adults with recurrent ependymoma

Phase I study of temsirolimus in pediatric patients with recurrent/refractory solid tumors

Phase I study of vandetanib during and after radiotherapy in children with diffuse intrinsic pontine glioma

Phase I trial of MK-0752 in children with refractory CNS malignancies: a pediatric brain tumor consortium study

Phase I trial of lapatinib in children with refractory CNS malignancies: a Pediatric Brain Tumor Consortium study

Phase I trial of weekly MK-0752 in children with refractory central nervous system malignancies: a pediatric brain tumor consortium study

Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation

Pten deletion causes mTorc1-dependent ectopic neuroblast differentiation without causing uniform migration defects

Radial glia cells are candidate stem cells of ependymoma

Rapid diagnosis of medulloblastoma molecular subgroups

Reply to 'Assembling the brain trust: the multidisciplinary imperative in neuro-oncology'

Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial

Risk-adapted therapy for young children with medulloblastoma (SJYC07): therapeutic and molecular outcomes from a multicentre, phase 2 trial

Siah regulation of Pard3A controls neuronal cell adhesion during germinal zone exit

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.

Subtypes of medulloblastoma have distinct developmental origins

The G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog-driven medulloblastoma

The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants

The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes.

The miR-17~92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma

The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation

Vismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog-Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032.

What's new in neuro-oncology? Recent advances in medulloblastoma ⬇️