Lista de obras - Beat Schafer - Dominio Público Uruguay

A novel complex regulates cardiac actin gene expression through interaction of Emb, a class VI POU domain protein, MEF2D, and the histone transacetylase p300

scientific journal article

Alpha-parvalbumin reduces depolarization-induced elevations of cytosolic free calcium in human neuroblastoma cells.

artículo científico publicado en 1996

Analysis of CA(2+)-binding S100 proteins in human heart by HPLC-electrospray mass spectrometry

artículo científico publicado en 1993

Anemia and survival in childhood acute lymphoblastic leukemia

artículo científico publicado en 2008

Array comparative genomic hybridization reveals unbalanced gain of the MYCN region in Wilms tumors.

artículo científico publicado en 2007

BAF complexes drive proliferation and block myogenic differentiation in fusion-positive rhabdomyosarcoma

artículo científico publicado en 2021

CD133 positive embryonal rhabdomyosarcoma stem-like cell population is enriched in rhabdospheres

artículo científico publicado en 2011

Ca(2+)-binding proteins S100A6 and S100B in primary cutaneous melanoma.

artículo científico publicado en 1997

Ca2+ -dependent interaction of S100A1 with the sarcoplasmic reticulum Ca2+ -ATPase2a and phospholamban in the human heart

artículo científico publicado en 2003

Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma.

artículo científico publicado en 2009

Cell-based small-molecule compound screen identifies fenretinide as potential therapeutic for translocation-positive rhabdomyosarcoma

artículo científico publicado en 2013

Characterization of the human S100A12 (calgranulin C, p6, CAAF1, CGRP) gene, a new member of the S100 gene cluster on chromosome 1q21

artículo científico publicado en 1996

Characterization of the human and mouse cDNAs coding for S100A13, a new member of the S100 protein family

artículo científico publicado en 1996

Clonal expansion of a new MLL rearrangement in the absence of leukemia

artículo científico publicado en 2005

Cloning and characterization of the human PAX7 promoter.

artículo científico publicado en 2000

Complementary DNA sequence and chromosomal mapping of a human proteoglycan-binding cell-adhesion protein (dermatopontin).

artículo científico publicado en 1993

Differential expression of S100B and S100A6(1) in the human fetal and aged cerebral cortex.

artículo científico publicado en 2000

Differential expression of the Ca2+ binding S100A6 protein in normal, preneoplastic and neoplastic colon mucosa

artículo científico publicado en 2000

Distinct gene expression profiles determine molecular treatment response in childhood acute lymphoblastic leukemia

artículo científico publicado en 2004

Expression analysis of S100 proteins and RAGE in human tumors using tissue microarrays

scientific article published on 01 July 2003

Expression of Ca(2+)-binding proteins of the S100 family in malignant human breast-cancer cell lines and biopsy samples

scientific article published on 01 June 1994

Expression of intracellular calcium-binding proteins in cultured skin fibroblasts from Alzheimer and normal aged donors.

artículo científico publicado en 1994

FGFR4 signaling couples to Bim and not Bmf to discriminate subsets of alveolar rhabdomyosarcoma cells.

artículo científico publicado en 2014

Fenretinide induces a new form of dynamin-dependent cell death in pediatric sarcoma

artículo científico publicado en 2020

Gene expression signatures identify rhabdomyosarcoma subtypes and detect a novel t(2;2)(q35;p23) translocation fusing PAX3 to NCOA1.

artículo científico publicado en 2004

Generation of a novel rtTA transgenic mouse to induce time-controlled, tissue-specific alterations in Pax2-expressing cells.

artículo científico publicado en 2011

Helicase CHD4 is an epigenetic coregulator of PAX3-FOXO1 in alveolar rhabdomyosarcoma

artículo científico publicado en 2016

Human alpha and beta parvalbumins. Structure and tissue-specific expression

artículo científico publicado en 1993

Human ferrochelatase: a novel mutation in patients with erythropoietic protoporphyria and an isoform caused by alternative splicing

scientific article published on 01 April 1995

Human recombinant alpha-parvalbumin and nine mutants with individually inactivated calcium- and magnesium-binding sites: biochemical and immunological properties.

artículo científico publicado en 1996

Identification of a rhabdomyosarcoma targeting peptide by phage display with sequence similarities to the tumour lymphatic-homing peptide LyP-1.

artículo científico publicado en 2009

Identification of novel DNA binding sites recognized by the transcription factor mPOU (POU6F1).

artículo científico publicado en 1996

Immunohistochemical localization of S100A1 and S100A6 in postnatally developing salivary glands of rats

artículo científico publicado en 1998

Induction of apoptosis in rhabdomyosarcoma cells through down-regulation of PAX proteins.

artículo científico publicado en 1996

Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance

artículo científico publicado en 2010

Interfering with Hedgehog Pathway: New Avenues for Targeted Therapy in Rhabdomyosarcoma

artículo científico

Inv(11)(p13p15) and myf-3(MyoD1) in a malignant extrarenal rhabdoid tumor of a premature newborn

scientific article published on 01 October 2000

Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study.

artículo científico publicado en 2011

Localization of Ca 2+ -binding S100 proteins in epithelial tumours of the skin ⬇️

artículo científico publicado el 1 de enero de 1998

Low-dose arsenic trioxide sensitizes glucocorticoid-resistant acute lymphoblastic leukemia cells to dexamethasone via an Akt-dependent pathway.

artículo científico publicado en 2007

Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leu

artículo científico publicado en 2008

Molecular cloning and characterization of a human PAX-7 cDNA expressed in normal and neoplastic myocytes

artículo científico publicado en 1994

Molecular cloning and characterization of the human S100A14 gene encoding a novel member of the S100 family

artículo científico publicado en 2002

Multidisciplinary management of childhood sarcoma: time to expand ⬇️

artículo científico publicado el 1 de agosto de 2010

New insights to the MLL recombinome of acute leukemias

artículo científico publicado en 2009

Novel FGFR4-Targeting Single-Domain Antibodies for Multiple Targeted Therapies against Rhabdomyosarcoma

artículo científico publicado en 2020

NuRD subunit CHD4 regulates super-enhancer accessibility in Rhabdomyosarcoma and represents a general tumor dependency ⬇️

artículo científico publicado en 2020

PI3K/AKT signaling modulates transcriptional expression of EWS/FLI1 through specificity protein 1.

artículo científico publicado en 2015

PLK1 phosphorylates PAX3-FOXO1, the inhibition of which triggers regression of alveolar Rhabdomyosarcoma.

artículo científico publicado en 2014

Phenotypic profiling with a living biobank of primary rhabdomyosarcoma unravels disease heterogeneity and AKT sensitivity

scientific article published on 15 September 2020

Phosphorylation regulates transcriptional activity of PAX3/FKHR and reveals novel therapeutic possibilities.

artículo científico publicado en 2008

Prediction of chromosomal aneuploidy from gene expression data.

artículo científico publicado en 2007

Preferred analysis methods for single genomic regions in RNA sequencing revealed by processing the shape of coverage.

artículo científico publicado en 2011

Prenatal origin of separate evolution of leukemia in identical twins.

artículo científico

Prognostic significance of the Ca(2+) binding protein S100A2 in laryngeal squamous-cell carcinoma.

artículo científico publicado en 2000

Proteasomal Degradation of the EWS-FLI1 Fusion Protein Is Regulated by a Single Lysine Residue.

artículo científico publicado en 2016

Purification and Cation Binding Properties of the Recombinant Human S100 Calcium-binding Protein A3, an EF-hand Motif Protein with High Affinity for Zinc ⬇️

artículo científico publicado el 8 de septiembre de 1995

Purification and characterization of the recombinant human calcium-binding S100 proteins CAPL and CACY

scientific journal article

Rapid molecular diagnosis of erythropoietic protoporphyria among Swiss patients

artículo científico publicado en 1998

Reduced-Intensity Delayed Intensification in Standard-Risk Pediatric Acute Lymphoblastic Leukemia Defined by Undetectable Minimal Residual Disease: Results of an International Randomized Trial (AIEOP-BFM ALL 2000).

artículo científico publicado en 2017

Repression of the candidate tumor suppressor gene S100A2 in breast cancer is mediated by site-specific hypermethylation ⬇️

artículo científico publicado el 1 de octubre de 1997

Rhabdomyosarcoma: current challenges and their implications for developing therapies.

artículo científico publicado en 2014

S100 alpha, CAPL, and CACY: molecular cloning and expression analysis of three calcium-binding proteins from human heart

artículo científico publicado el 27 de octubre de 1992

S100 protein translocation in response to extracellular S100 is mediated by receptor for advanced glycation endproducts in human endothelial cells

artículo científico publicado en 2004

S100 proteins in Corpora amylacea from normal human brain.

artículo científico publicado en 2000

S100A2, a Putative Tumor Suppressor Gene, Regulates In Vitro Squamous Cell Carcinoma Migration

article

Selective association of S100A6 (calcyclin)-immunoreactive astrocytes with the tangential migration pathway of subventricular zone cells in the rat ⬇️

artículo científico publicado el 19 de diciembre de 1997

Structural insight into human Zn(2+)-bound S100A2 from NMR and homology modeling.

artículo científico publicado en 2001

Subtype and prognostic classification of rhabdomyosarcoma by immunohistochemistry

scientific article published on 03 January 2006

Targeting hedgehog signaling reduces self-renewal in embryonal rhabdomyosarcoma

artículo científico publicado en 2015

Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma

artículo científico publicado en 2015

The LIM-only protein FHL2 is a negative regulator of E4F1

artículo científico publicado en 2006

The MLL recombinome of acute leukemias

scientific article published on 01 May 2006

The MLL recombinome of acute leukemias in 2013.

artículo científico publicado en 2013

The MLL recombinome of acute leukemias in 2017.

artículo científico

The PAX5 oncogene is expressed in N-type neuroblastoma cells and increases tumorigenicity of a S-type cell line.

artículo científico publicado en 2004

The Proprotein Convertase Furin Contributes to Rhabdomyosarcoma Malignancy by Promoting Vascularization, Migration and Invasion.

artículo científico publicado en 2016

The S100 family of EF-hand calcium-binding proteins: functions and pathology

artículo científico publicado en 1996

The calcium-binding protein S100A2 interacts with p53 and modulates its transcriptional activity.

artículo científico publicado en 2005

The human paired domain gene PAX7 (Hup1) maps to chromosome 1p35-1p36.2

artículo científico publicado en 1993

The in vivo form of the murine class VI POU protein Emb is larger than that encoded by previously described transcripts.

artículo científico publicado en 2004

The primary structure of chicken B-creatine kinase and evidence for heterogeneity of its mRNA.

artículo científico publicado en 1986

The proprotein convertase furin is required to maintain viability of alveolar rhabdomyosarcoma cells

artículo científico publicado en 2016

The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease

artículo científico publicado en 2016

The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo.

artículo científico publicado en 2003

Transcriptional activation of the human S100A2 promoter by wild-type p53

scientific article published on 01 February 1999

USP19 deubiquitinates EWS-FLI1 to regulate Ewing sarcoma growth

artículo científico publicado en 2019

Unpeaceful roles of mutant PAX proteins in cancer

artículo científico publicado en 2015

YAP/TAZ inhibition reduces metastatic potential of Ewing sarcoma cells

artículo científico publicado en 2021

p21 Downregulation is an important component of PAX3/FKHR oncogenicity and its reactivation by HDAC inhibitors enhances combination treatment.

artículo científico publicado en 2010

Lista de obras de Beat Schafer

A novel complex regulates cardiac actin gene expression through interaction of Emb, a class VI POU domain protein, MEF2D, and the histone transacetylase p300

Alpha-parvalbumin reduces depolarization-induced elevations of cytosolic free calcium in human neuroblastoma cells.

Analysis of CA(2+)-binding S100 proteins in human heart by HPLC-electrospray mass spectrometry

Anemia and survival in childhood acute lymphoblastic leukemia

Array comparative genomic hybridization reveals unbalanced gain of the MYCN region in Wilms tumors.

BAF complexes drive proliferation and block myogenic differentiation in fusion-positive rhabdomyosarcoma

CD133 positive embryonal rhabdomyosarcoma stem-like cell population is enriched in rhabdospheres

Ca(2+)-binding proteins S100A6 and S100B in primary cutaneous melanoma.

Ca2+ -dependent interaction of S100A1 with the sarcoplasmic reticulum Ca2+ -ATPase2a and phospholamban in the human heart

Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma.

Cell-based small-molecule compound screen identifies fenretinide as potential therapeutic for translocation-positive rhabdomyosarcoma

Characterization of the human S100A12 (calgranulin C, p6, CAAF1, CGRP) gene, a new member of the S100 gene cluster on chromosome 1q21

Characterization of the human and mouse cDNAs coding for S100A13, a new member of the S100 protein family

Clonal expansion of a new MLL rearrangement in the absence of leukemia

Cloning and characterization of the human PAX7 promoter.

Complementary DNA sequence and chromosomal mapping of a human proteoglycan-binding cell-adhesion protein (dermatopontin).

Differential expression of S100B and S100A6(1) in the human fetal and aged cerebral cortex.

Differential expression of the Ca2+ binding S100A6 protein in normal, preneoplastic and neoplastic colon mucosa

Distinct gene expression profiles determine molecular treatment response in childhood acute lymphoblastic leukemia

Expression analysis of S100 proteins and RAGE in human tumors using tissue microarrays

Expression of Ca(2+)-binding proteins of the S100 family in malignant human breast-cancer cell lines and biopsy samples

Expression of intracellular calcium-binding proteins in cultured skin fibroblasts from Alzheimer and normal aged donors.

FGFR4 signaling couples to Bim and not Bmf to discriminate subsets of alveolar rhabdomyosarcoma cells.

Fenretinide induces a new form of dynamin-dependent cell death in pediatric sarcoma

Gene expression signatures identify rhabdomyosarcoma subtypes and detect a novel t(2;2)(q35;p23) translocation fusing PAX3 to NCOA1.

Generation of a novel rtTA transgenic mouse to induce time-controlled, tissue-specific alterations in Pax2-expressing cells.

Helicase CHD4 is an epigenetic coregulator of PAX3-FOXO1 in alveolar rhabdomyosarcoma

Human alpha and beta parvalbumins. Structure and tissue-specific expression

Human ferrochelatase: a novel mutation in patients with erythropoietic protoporphyria and an isoform caused by alternative splicing

Human recombinant alpha-parvalbumin and nine mutants with individually inactivated calcium- and magnesium-binding sites: biochemical and immunological properties.

Identification of a rhabdomyosarcoma targeting peptide by phage display with sequence similarities to the tumour lymphatic-homing peptide LyP-1.

Identification of novel DNA binding sites recognized by the transcription factor mPOU (POU6F1).

Immunohistochemical localization of S100A1 and S100A6 in postnatally developing salivary glands of rats

Induction of apoptosis in rhabdomyosarcoma cells through down-regulation of PAX proteins.

Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance

Interfering with Hedgehog Pathway: New Avenues for Targeted Therapy in Rhabdomyosarcoma

Inv(11)(p13p15) and myf-3(MyoD1) in a malignant extrarenal rhabdoid tumor of a premature newborn

Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study.

Localization of Ca 2+ -binding S100 proteins in epithelial tumours of the skin ⬇️

Low-dose arsenic trioxide sensitizes glucocorticoid-resistant acute lymphoblastic leukemia cells to dexamethasone via an Akt-dependent pathway.

Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leu

Molecular cloning and characterization of a human PAX-7 cDNA expressed in normal and neoplastic myocytes

Molecular cloning and characterization of the human S100A14 gene encoding a novel member of the S100 family

Multidisciplinary management of childhood sarcoma: time to expand ⬇️

New insights to the MLL recombinome of acute leukemias

Novel FGFR4-Targeting Single-Domain Antibodies for Multiple Targeted Therapies against Rhabdomyosarcoma

NuRD subunit CHD4 regulates super-enhancer accessibility in Rhabdomyosarcoma and represents a general tumor dependency ⬇️

PI3K/AKT signaling modulates transcriptional expression of EWS/FLI1 through specificity protein 1.

PLK1 phosphorylates PAX3-FOXO1, the inhibition of which triggers regression of alveolar Rhabdomyosarcoma.

Phenotypic profiling with a living biobank of primary rhabdomyosarcoma unravels disease heterogeneity and AKT sensitivity

Phosphorylation regulates transcriptional activity of PAX3/FKHR and reveals novel therapeutic possibilities.

Prediction of chromosomal aneuploidy from gene expression data.

Preferred analysis methods for single genomic regions in RNA sequencing revealed by processing the shape of coverage.

Prenatal origin of separate evolution of leukemia in identical twins.

Prognostic significance of the Ca(2+) binding protein S100A2 in laryngeal squamous-cell carcinoma.

Proteasomal Degradation of the EWS-FLI1 Fusion Protein Is Regulated by a Single Lysine Residue.

Purification and Cation Binding Properties of the Recombinant Human S100 Calcium-binding Protein A3, an EF-hand Motif Protein with High Affinity for Zinc ⬇️

Purification and characterization of the recombinant human calcium-binding S100 proteins CAPL and CACY

Rapid molecular diagnosis of erythropoietic protoporphyria among Swiss patients

Reduced-Intensity Delayed Intensification in Standard-Risk Pediatric Acute Lymphoblastic Leukemia Defined by Undetectable Minimal Residual Disease: Results of an International Randomized Trial (AIEOP-BFM ALL 2000).

Repression of the candidate tumor suppressor gene S100A2 in breast cancer is mediated by site-specific hypermethylation ⬇️

Rhabdomyosarcoma: current challenges and their implications for developing therapies.

S100 alpha, CAPL, and CACY: molecular cloning and expression analysis of three calcium-binding proteins from human heart

S100 protein translocation in response to extracellular S100 is mediated by receptor for advanced glycation endproducts in human endothelial cells

S100 proteins in Corpora amylacea from normal human brain.

S100A2, a Putative Tumor Suppressor Gene, Regulates In Vitro Squamous Cell Carcinoma Migration

Selective association of S100A6 (calcyclin)-immunoreactive astrocytes with the tangential migration pathway of subventricular zone cells in the rat ⬇️

Structural insight into human Zn(2+)-bound S100A2 from NMR and homology modeling.

Subtype and prognostic classification of rhabdomyosarcoma by immunohistochemistry

Targeting hedgehog signaling reduces self-renewal in embryonal rhabdomyosarcoma

Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma

The LIM-only protein FHL2 is a negative regulator of E4F1

The MLL recombinome of acute leukemias

The MLL recombinome of acute leukemias in 2013.

The MLL recombinome of acute leukemias in 2017.

The PAX5 oncogene is expressed in N-type neuroblastoma cells and increases tumorigenicity of a S-type cell line.

The Proprotein Convertase Furin Contributes to Rhabdomyosarcoma Malignancy by Promoting Vascularization, Migration and Invasion.

The S100 family of EF-hand calcium-binding proteins: functions and pathology

The calcium-binding protein S100A2 interacts with p53 and modulates its transcriptional activity.