Lista de obras -

Analysis of clonal expansions through the normal and premalignant human breast epithelium reveals the presence of luminal stem cells.

artículo científico publicado en 2017

Analysis of the clonal architecture of the human small intestinal epithelium establishes a common stem cell for all lineages and reveals a mechanism for the fixation and spread of mutations.

artículo científico publicado en 2009

Barrett oesophagus: lessons on its origins from the lesion itself

artículo científico publicado en 2014

Barrett's metaplasia glands are clonal, contain multiple stem cells and share a common squamous progenitor.

artículo científico publicado en 2011

Bullying at Barts

artículo científico

Cell migration leads to spatially distinct but clonally related airway cancer precursors.

artículo científico publicado en 2014

Characterization of the mucosal cell-mediated immune response in IL-2 knockout mice before and after the onset of colitis

artículo científico publicado en 1997

Clonal Transitions and Phenotypic Evolution in Barrett’s Esophagus

artículo científico publicado en 2022

Clonal expansion in the human gut: mitochondrial DNA mutations show us the way.

artículo científico publicado en 2006

Clonal selection and persistence in dysplastic Barrett's esophagus and intramucosal cancers after failed radiofrequency ablation.

artículo científico publicado en 2013

Clonality Assessment and Clonal Ordering of Individual Neoplastic Crypts Shows Polyclonality of Colorectal Adenomas

artículo científico publicado en 2010

Clonality, Founder Mutations, and Field Cancerization in Human Ulcerative Colitis–Associated Neoplasia

artículo científico publicado en 2008

Crypt dysplasia in Barrett's oesophagus shows clonal identity between crypt and surface cells.

artículo científico publicado en 2013

Crypt fusion as a homeostatic mechanism in the human colon

artículo científico publicado en 2019

Detection of intestinal metaplasia in Barrett's esophagus: an observational comparator study suggests the need for a minimum of eight biopsies.

artículo científico publicado en 2007

Dual-action combination therapy enhances angiogenesis while reducing tumor growth and spread

artículo científico publicado en 2015

Ectopic expression of P-cadherin correlates with promoter hypomethylation early in colorectal carcinogenesis and enhanced intestinal crypt fission in vivo.

artículo científico publicado en 2008

Evolution of oesophageal adenocarcinoma from metaplastic columnar epithelium without goblet cells in Barrett's oesophagus

artículo científico publicado en 2015

Field cancerization in the GI tract.

artículo científico

Field cancerization in the intestinal epithelium of patients with Crohn's ileocolitis.

artículo científico publicado en 2011

Genetic diversity during the development of Barrett's oesophagus-associated adenocarcinoma: how, when and why?

artículo científico publicado en 2010

Hepatocytes undergo punctuated expansion dynamics from a periportal stem cell niche in normal human liver

scientific article published in 2023

Identification of lineage-uncommitted, long-lived, label-retaining cells in healthy human esophagus and stomach, and in metaplastic esophagus.

artículo científico publicado en 2012

Inherited pathogenic mitochondrial DNA mutations and gastrointestinal stem cell populations

scientific article published on 05 November 2018

Intestinal stem cells

artículo científico publicado en 2005

Lineage tracing reveals multipotent stem cells maintain human adenomas and the pattern of clonal expansion in tumor evolution.

artículo científico publicado en 2013

Mechanisms of disease: from stem cells to colorectal cancer.

artículo científico publicado en 2006

Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission.

artículo científico publicado en 2006

Protection of mitochondrial genome integrity: a new stem cell property?

artículo científico publicado en 2010

Quantification of crypt and stem cell evolution in the normal and neoplastic human colon

artículo científico publicado en 2014

Re: Mitochondria and tumor progression in ulcerative colitis.

artículo científico publicado en 2014

Squamous cell carcinoma after radiofrequency ablation for Barrett's dysplasia.

artículo científico publicado en 2014

Stem cells and inflammation in the intestine.

artículo científico publicado en 2011

Stochastic homeostasis in human airway epithelium is achieved by neutral competition of basal cell progenitors

artículo científico publicado en 2013

Superficial Esophageal Mucosal Afferent Nerves May Contribute to Reflux Hypersensitivity in Nonerosive Reflux Disease.

artículo científico publicado en 2017

Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway

scientific journal article

The Barrett's Gland in Phenotype Space.

artículo científico publicado en 2014

The Complex, Clonal, and Controversial Nature of Barrett's Esophagus

artículo científico publicado en 2016

The clonal origins of dysplasia from intestinal metaplasia in the human stomach.

artículo científico publicado en 2011

The stem cell organisation, and the proliferative and gene expression profile of Barrett's epithelium, replicates pyloric-type gastric glands

artículo científico publicado en 2014

Use of methylation patterns to determine expansion of stem cell clones in human colon tissue.

artículo científico publicado en 2010

Lista de obras de

Analysis of clonal expansions through the normal and premalignant human breast epithelium reveals the presence of luminal stem cells.

Analysis of the clonal architecture of the human small intestinal epithelium establishes a common stem cell for all lineages and reveals a mechanism for the fixation and spread of mutations.

Barrett oesophagus: lessons on its origins from the lesion itself

Barrett's metaplasia glands are clonal, contain multiple stem cells and share a common squamous progenitor.

Bullying at Barts

Cell migration leads to spatially distinct but clonally related airway cancer precursors.

Characterization of the mucosal cell-mediated immune response in IL-2 knockout mice before and after the onset of colitis

Clonal Transitions and Phenotypic Evolution in Barrett’s Esophagus

Clonal expansion in the human gut: mitochondrial DNA mutations show us the way.

Clonal selection and persistence in dysplastic Barrett's esophagus and intramucosal cancers after failed radiofrequency ablation.

Clonality Assessment and Clonal Ordering of Individual Neoplastic Crypts Shows Polyclonality of Colorectal Adenomas

Clonality, Founder Mutations, and Field Cancerization in Human Ulcerative Colitis–Associated Neoplasia

Crypt dysplasia in Barrett's oesophagus shows clonal identity between crypt and surface cells.

Crypt fusion as a homeostatic mechanism in the human colon

Detection of intestinal metaplasia in Barrett's esophagus: an observational comparator study suggests the need for a minimum of eight biopsies.

Dual-action combination therapy enhances angiogenesis while reducing tumor growth and spread

Ectopic expression of P-cadherin correlates with promoter hypomethylation early in colorectal carcinogenesis and enhanced intestinal crypt fission in vivo.

Evolution of oesophageal adenocarcinoma from metaplastic columnar epithelium without goblet cells in Barrett's oesophagus

Field cancerization in the GI tract.

Field cancerization in the intestinal epithelium of patients with Crohn's ileocolitis.

Genetic diversity during the development of Barrett's oesophagus-associated adenocarcinoma: how, when and why?

Hepatocytes undergo punctuated expansion dynamics from a periportal stem cell niche in normal human liver

Identification of lineage-uncommitted, long-lived, label-retaining cells in healthy human esophagus and stomach, and in metaplastic esophagus.

Inherited pathogenic mitochondrial DNA mutations and gastrointestinal stem cell populations

Intestinal stem cells

Lineage tracing reveals multipotent stem cells maintain human adenomas and the pattern of clonal expansion in tumor evolution.

Mechanisms of disease: from stem cells to colorectal cancer.

Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission.

Protection of mitochondrial genome integrity: a new stem cell property?

Quantification of crypt and stem cell evolution in the normal and neoplastic human colon

Re: Mitochondria and tumor progression in ulcerative colitis.

Squamous cell carcinoma after radiofrequency ablation for Barrett's dysplasia.

Stem cells and inflammation in the intestine.

Stochastic homeostasis in human airway epithelium is achieved by neutral competition of basal cell progenitors

Superficial Esophageal Mucosal Afferent Nerves May Contribute to Reflux Hypersensitivity in Nonerosive Reflux Disease.

Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway

The Barrett's Gland in Phenotype Space.

The Complex, Clonal, and Controversial Nature of Barrett's Esophagus

The clonal origins of dysplasia from intestinal metaplasia in the human stomach.

The stem cell organisation, and the proliferative and gene expression profile of Barrett's epithelium, replicates pyloric-type gastric glands

Use of methylation patterns to determine expansion of stem cell clones in human colon tissue.