Lista de obras - Michael J Ausserlechner - Dominio Público Uruguay

A conceptual view on glucocorticoid-lnduced apoptosis, cell cycle arrest and glucocorticoid resistance in lymphoblastic leukemia

artículo científico publicado en 2003

A drug library screen identifies Carbenoxolone as novel FOXO inhibitor that overcomes FOXO3-mediated chemoprotection in high-stage neuroblastoma

artículo científico publicado en 2019

A novel Mcl1 variant inhibits apoptosis via increased Bim sequestration ⬇️

artículo científico publicado el 1 de agosto de 2013

Altered procollagen mRNA expression during the progression of avian scleroderma.

artículo científico publicado en 1997

Apoptosis induced by the histone deacetylase inhibitor sodium butyrate in human leukemic lymphoblasts.

artículo científico publicado en 1999

BIRC5/Survivin as a target for glycolysis inhibition in high-stage neuroblastoma.

artículo científico publicado en 2015

BIRC5/Survivin enhances aerobic glycolysis and drug resistance by altered regulation of the mitochondrial fusion/fission machinery.

artículo científico publicado en 2012

C10ORF10/DEPP, a transcriptional target of FOXO3, regulates ROS-sensitivity in human neuroblastoma.

artículo científico publicado en 2014

C10ORF10/DEPP-mediated ROS accumulation is a critical modulator of FOXO3-induced autophagy

artículo científico publicado en 2017

Characterization of the XIAP-Inhibiting Proanthocyanidin Fraction of the Aerial Parts of Ephedra sinica.

artículo científico publicado en 2016

Chemiluminescence-based RNase protection assays for simultaneous quantification of procollagen mRNAs containing AU-rich regions

scientific article published on 01 March 1998

Crosstalk between Mitochondria and Cytoskeleton in Cardiac Cells

scientific article published on 16 January 2020

Cyclin D3 and c-MYC control glucocorticoid-induced cell cycle arrest but not apoptosis in lymphoblastic leukemia cells.

artículo científico publicado en 2004

Discovery of Sanggenon G as a natural cell-permeable small-molecular weight inhibitor of X-linked inhibitor of apoptosis protein (XIAP).

artículo científico publicado en 2014

FKHRL1-mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cells

artículo científico publicado en 2007

FOXO3-induced reactive oxygen species are regulated by BCL2L11 (Bim) and SESN3.

artículo científico publicado en 2012

FOXO3-mediated chemo-protection in high-stage neuroblastoma depends on wild-type TP53 and SESN3.

artículo científico publicado en 2017

FOXO3/FKHRL1 is activated by 5-aza-2-deoxycytidine and induces silenced caspase-8 in neuroblastoma

artículo científico publicado en 2012

Forkhead Domains of FOXO Transcription Factors Differ in both Overall Conformation and Dynamics

scientific article published on 24 August 2019

Functional analysis of the mutated Epstein-Barr virus oncoprotein LMP1(69del): implications for a new role of naturally occurring LMP1 variants.

artículo científico publicado en 2003

G1 arrest by p16INK4A uncouples growth from cell cycle progression in leukemia cells with deregulated cyclin E and c-Myc expression

artículo científico publicado en 2005

Gene expression profiles of proliferating vs. G1/G0 arrested human leukemia cells suggest a mechanism for glucocorticoid-induced apoptosis.

artículo científico publicado en 2001

Lipidomic and Proteomic Alterations Induced by Even and Odd Medium-Chain Fatty Acids on Fibroblasts of Long-Chain Fatty Acid Oxidation Disorders

artículo científico publicado en 2021

Mitochondria and FOXO3: breath or die

artículo científico publicado en 2013

Mitochondrial survivin - an Achilles' heel in cancer chemoresistance.

artículo científico publicado en 2015

Modulating FOXO3 transcriptional activity by small, DBD-binding molecules

artículo científico publicado en 2019

Modulation of Respiration and Mitochondrial Dynamics by SMAC-Mimetics for Combination Therapy in Chemoresistant Cancer

artículo científico publicado en 2019

Nuclear FOXO3 predicts adverse clinical outcome and promotes tumor angiogenesis in neuroblastoma.

scientific article published on 18 October 2016

Oxindole alkaloids from Uncaria tomentosa induce apoptosis in proliferating, G0/G1-arrested and bcl-2-expressing acute lymphoblastic leukaemia cells ⬇️

artículo científico publicado en 2006

Premature aging of the immune system in children with juvenile idiopathic arthritis

artículo científico publicado en 2008

Repaglinide Silences the FOXO3/Lumican Axis and Represses the Associated Metastatic Potential of Neuronal Cancer Cells

scientific article published on 18 December 2019

Resistance to glucocorticoid-induced apoptosis in lymphoblastic leukemia.

artículo científico publicado en 2003

Successful transplantation in a child with rapid progression of autosomal recessive polycystic kidney disease associated with a novel mutation.

artículo científico publicado en 2006

Targeting transcription factors by small compounds--Current strategies and future implications.

artículo científico

The Role of Mitochondria in the Mechanisms of Cardiac Ischemia-Reperfusion Injury

artículo científico publicado en 2019

The anti-apoptotic protein BCL2L1/Bcl-xL is neutralized by pro-apoptotic PMAIP1/Noxa in neuroblastoma, thereby determining bortezomib sensitivity independent of prosurvival MCL1 expression.

artículo científico publicado en 2010

The cell cycle inhibitor p16(INK4A) sensitizes lymphoblastic leukemia cells to apoptosis by physiologic glucocorticoid levels

scientific article published on 12 January 2001

The cell senescence inducing gene product MORF4 is regulated by degradation via the ubiquitin/proteasome pathway.

artículo científico publicado en 2009

The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species

artículo científico publicado en 2001

The tubulin inhibitor MG-2477 induces autophagy-regulated cell death, ROS accumulation and activation of FOXO3 in neuroblastoma

artículo científico publicado en 2017

Therapy-resistant acute lymphoblastic leukemia (ALL) cells inactivate FOXO3 to escape apoptosis induction by TRAIL and Noxa

artículo científico publicado en 2013

Toll-like receptor 9 expression in breast and ovarian cancer is associated with poorly differentiated tumors

artículo científico publicado en 2010

Very long-/ and long Chain-3-Hydroxy Acyl CoA Dehydrogenase Deficiency correlates with deregulation of the mitochondrial fusion/fission machinery.

artículo científico publicado en 2018

X-linked inhibitor of apoptosis protein - a critical death resistance regulator and therapeutic target for personalized cancer therapy.

artículo científico publicado en 2014

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

artículo científico publicado en 2003

p53-induced apoptosis in the human T-ALL cell line CCRF-CEM.

artículo científico publicado en 1997

Lista de obras de Michael J Ausserlechner

A conceptual view on glucocorticoid-lnduced apoptosis, cell cycle arrest and glucocorticoid resistance in lymphoblastic leukemia

A drug library screen identifies Carbenoxolone as novel FOXO inhibitor that overcomes FOXO3-mediated chemoprotection in high-stage neuroblastoma

A novel Mcl1 variant inhibits apoptosis via increased Bim sequestration ⬇️

Altered procollagen mRNA expression during the progression of avian scleroderma.

Apoptosis induced by the histone deacetylase inhibitor sodium butyrate in human leukemic lymphoblasts.

BIRC5/Survivin as a target for glycolysis inhibition in high-stage neuroblastoma.

BIRC5/Survivin enhances aerobic glycolysis and drug resistance by altered regulation of the mitochondrial fusion/fission machinery.

C10ORF10/DEPP, a transcriptional target of FOXO3, regulates ROS-sensitivity in human neuroblastoma.

C10ORF10/DEPP-mediated ROS accumulation is a critical modulator of FOXO3-induced autophagy

Characterization of the XIAP-Inhibiting Proanthocyanidin Fraction of the Aerial Parts of Ephedra sinica.

Chemiluminescence-based RNase protection assays for simultaneous quantification of procollagen mRNAs containing AU-rich regions

Crosstalk between Mitochondria and Cytoskeleton in Cardiac Cells

Cyclin D3 and c-MYC control glucocorticoid-induced cell cycle arrest but not apoptosis in lymphoblastic leukemia cells.

Discovery of Sanggenon G as a natural cell-permeable small-molecular weight inhibitor of X-linked inhibitor of apoptosis protein (XIAP).

FKHRL1-mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cells

FOXO3-induced reactive oxygen species are regulated by BCL2L11 (Bim) and SESN3.

FOXO3-mediated chemo-protection in high-stage neuroblastoma depends on wild-type TP53 and SESN3.

FOXO3/FKHRL1 is activated by 5-aza-2-deoxycytidine and induces silenced caspase-8 in neuroblastoma

Forkhead Domains of FOXO Transcription Factors Differ in both Overall Conformation and Dynamics

Functional analysis of the mutated Epstein-Barr virus oncoprotein LMP1(69del): implications for a new role of naturally occurring LMP1 variants.

G1 arrest by p16INK4A uncouples growth from cell cycle progression in leukemia cells with deregulated cyclin E and c-Myc expression

Gene expression profiles of proliferating vs. G1/G0 arrested human leukemia cells suggest a mechanism for glucocorticoid-induced apoptosis.

Lipidomic and Proteomic Alterations Induced by Even and Odd Medium-Chain Fatty Acids on Fibroblasts of Long-Chain Fatty Acid Oxidation Disorders

Mitochondria and FOXO3: breath or die

Mitochondrial survivin - an Achilles' heel in cancer chemoresistance.

Modulating FOXO3 transcriptional activity by small, DBD-binding molecules

Modulation of Respiration and Mitochondrial Dynamics by SMAC-Mimetics for Combination Therapy in Chemoresistant Cancer

Nuclear FOXO3 predicts adverse clinical outcome and promotes tumor angiogenesis in neuroblastoma.

Oxindole alkaloids from Uncaria tomentosa induce apoptosis in proliferating, G0/G1-arrested and bcl-2-expressing acute lymphoblastic leukaemia cells ⬇️

Premature aging of the immune system in children with juvenile idiopathic arthritis

Repaglinide Silences the FOXO3/Lumican Axis and Represses the Associated Metastatic Potential of Neuronal Cancer Cells

Resistance to glucocorticoid-induced apoptosis in lymphoblastic leukemia.

Successful transplantation in a child with rapid progression of autosomal recessive polycystic kidney disease associated with a novel mutation.

Targeting transcription factors by small compounds--Current strategies and future implications.

The Role of Mitochondria in the Mechanisms of Cardiac Ischemia-Reperfusion Injury

The anti-apoptotic protein BCL2L1/Bcl-xL is neutralized by pro-apoptotic PMAIP1/Noxa in neuroblastoma, thereby determining bortezomib sensitivity independent of prosurvival MCL1 expression.

The cell cycle inhibitor p16(INK4A) sensitizes lymphoblastic leukemia cells to apoptosis by physiologic glucocorticoid levels

The cell senescence inducing gene product MORF4 is regulated by degradation via the ubiquitin/proteasome pathway.

The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species

The tubulin inhibitor MG-2477 induces autophagy-regulated cell death, ROS accumulation and activation of FOXO3 in neuroblastoma

Therapy-resistant acute lymphoblastic leukemia (ALL) cells inactivate FOXO3 to escape apoptosis induction by TRAIL and Noxa

Toll-like receptor 9 expression in breast and ovarian cancer is associated with poorly differentiated tumors

Very long-/ and long Chain-3-Hydroxy Acyl CoA Dehydrogenase Deficiency correlates with deregulation of the mitochondrial fusion/fission machinery.

X-linked inhibitor of apoptosis protein - a critical death resistance regulator and therapeutic target for personalized cancer therapy.

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

p53-induced apoptosis in the human T-ALL cell line CCRF-CEM.