Lista de obras - Hernando A del Portillo Obando

A functional microengineered model of the human splenon-on-a-chip

artículo científico publicado en 2014

A new computational approach redefines the subtelomeric vir superfamily of Plasmodium vivax.

artículo científico publicado en 2013

A reduced risk of infection with Plasmodium vivax and clinical protection against malaria are associated with antibodies against the N terminus but not the C terminus of merozoite surface protein 1.

artículo científico publicado en 2006

A superfamily of variant genes encoded in the subtelomeric region of Plasmodium vivax

artículo científico publicado en 2001

Advances toward the development of an asexual blood stage MSP-1 vaccine of Plasmodium vivax.

artículo científico publicado en 1994

Analysis of single-nucleotide polymorphisms in the crt-o and mdr1 genes of Plasmodium vivax among chloroquine-resistant isolates from the Brazilian Amazon region

artículo científico publicado en 2009

Antigenic properties of the merozoite surface protein 1 gene of Plasmodium vivax

artículo científico publicado en 1999

Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper.

artículo científico publicado en 2015

Biological properties of extracellular vesicles and their physiological functions.

artículo científico publicado en 2015

Characterisation of the Cdc2-related kinase 2 gene from Plasmodium knowlesi and P. berghei.

artículo científico publicado en 1998

Characterization of Plasmodium vivax Proteins in Plasma-Derived Exosomes From Malaria-Infected Liver-Chimeric Humanized Mice.

artículo científico publicado en 2018

Circumsporozoite gene of a Plasmodium falciparum strain from Thailand

artículo científico publicado en 1987

Comparison of diagnostic methods for the detection and quantification of the four sympatric Plasmodium species in field samples from Papua New Guinea

artículo científico publicado en 2010

Comparison of introns in a cdc2-homologous gene within a number of Plasmodium species.

artículo científico publicado en 1995

Concise Review: Developing Best-Practice Models for the Therapeutic Use of Extracellular Vesicles.

artículo científico publicado en 2017

Corrigendum: Spleen-Dependent Immune Protection Elicited by CpG Adjuvanted Reticulocyte-Derived Exosomes from Malaria Infection Is Associated with Changes in T Cell Subsets' Distribution.

artículo científico publicado en 2016

EVpedia: a community web portal for extracellular vesicles research

artículo científico publicado en 2014

Effect of immunosuppression in miRNAs from extracellular vesicles of colorectal cancer and their influence on the pre-metastatic niche

artículo científico publicado en 2019

Evaluation of the acquired immune responses to Plasmodium vivax VIR variant antigens in individuals living in malaria-endemic areas of Brazil

artículo científico publicado en 2006

Evidence for different mechanisms of chloroquine resistance in 2 Plasmodium species that cause human malaria.

artículo científico publicado en 2001

Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine

artículo científico publicado en 2016

Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections.

artículo científico publicado en 2011

Expression and function of pvcrt-o, a Plasmodium vivax ortholog of pfcrt, in Plasmodium falciparum and Dictyostelium discoideum.

artículo científico publicado en 2006

Expression levels of pvcrt-o and pvmdr-1 are associated with chloroquine resistance and severe Plasmodium vivax malaria in patients of the Brazilian Amazon.

artículo científico publicado en 2014

Expression of non-TLR pattern recognition receptors in the spleen of BALB/c mice infected with Plasmodium yoelii and Plasmodium chabaudi chabaudi AS.

artículo científico publicado en 2012

Extracellular vesicles in parasitic diseases

artículo científico publicado en 2014

Functional analysis of Plasmodium vivax VIR proteins reveals different subcellular localizations and cytoadherence to the ICAM-1 endothelial receptor.

artículo científico publicado en 2011

Genetic immunization of BALB/c mice with a plasmid bearing the gene coding for a hybrid merozoite surface protein 1-hepatitis B virus surface protein fusion protects mice against lethal Plasmodium chabaudi chabaudi PC1 infection

artículo científico publicado en 2000

Heat shock induction of apoptosis in promastigotes of the unicellular organism Leishmania (Leishmania) amazonensis

scientific article published on 01 May 1996

Highlights of the São Paulo ISEV workshop on extracellular vesicles in cross-kingdom communication.

artículo científico publicado en 2017

Human IgG responses against the N-terminal region of the Merozoite Surface Protein 1 of Plasmodium vivax

artículo científico publicado en 1992

Human Splenon-on-a-chip: Design and Validation of a Microfluidic Model Resembling the Interstitial Slits and the Close/Fast and Open/Slow Microcirculations

Imaging of the spleen in malaria.

artículo científico publicado en 2013

In vivo and in vitro characterization of a Plasmodium liver stage-specific promoter

artículo científico publicado en 2015

Increased expression levels of the pvcrt-o and pvmdr1 genes in a patient with severe Plasmodium vivax malaria

artículo científico publicado en 2009

Intravital microscopy of the spleen: quantitative analysis of parasite mobility and blood flow

artículo científico publicado en 2012

Key gaps in the knowledge of Plasmodium vivax, a neglected human malaria parasite

artículo científico publicado en 2009

Malaria parasites contain two identical copies of an elongation factor 1 alpha gene.

artículo científico publicado en 1998

Malaria parasites lacking eef1a have a normal S/M phase yet grow more slowly due to a longer G1 phase.

artículo científico publicado en 2003

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

scientific article published on 23 November 2018

Mining the malaria transcriptome.

artículo científico publicado en 2005

Molecular analysis of Plasmodium vivax relapses using the MSP1 molecule as a genetic marker.

artículo científico publicado en 1998

Naturally Acquired Binding-Inhibitory Antibodies to Plasmodium vivax Duffy Binding Protein in Pregnant Women Are Associated with Higher Birth Weight in a Multicenter Study

scientific article published on 17 February 2017

Naturally-acquired humoral immune responses against the N- and C-termini of the Plasmodium vivax MSP1 protein in endemic regions of Brazil and Papua New Guinea using a multiplex assay

artículo científico publicado en 2010

On cytoadhesion of Plasmodium vivax: raison d'être?

artículo científico publicado en 2011

On the cytoadhesion of Plasmodium vivax-infected erythrocytes

artículo científico publicado en 2010

Origins of sequence diversity in the malaria vaccine candidate merozoite surface protein-2 (MSP-2) in Amazonian isolates of Plasmodium falciparum.

artículo científico publicado en 2006

Paucity of Plasmodium vivax mature schizonts in peripheral blood is associated with their increased cytoadhesive potential

artículo científico publicado en 2014

Placental infection with Plasmodium vivax: a histopathological and molecular study

artículo científico publicado en 2012

Plasma-derived extracellular vesicles from Plasmodium vivax patients signal spleen fibroblasts via NF-kB facilitating parasite cytoadherence

artículo científico publicado en 2020

Plasmodium falciparum: DBL-1 var sequence analysis in field isolates from central Brazil.

artículo científico publicado en 2000

Plasmodium falciparum: epidemiological studies on the circumsporozoite gene

artículo científico publicado en 1987

Plasmodium falciparum: new vector with bi-directional promoter activity to stably express transgenes

artículo científico publicado en 2003

Plasmodium vivax VIR Proteins Are Targets of Naturally-Acquired Antibody and T Cell Immune Responses to Malaria in Pregnant Women

artículo científico publicado en 2016

Plasmodium vivax and the importance of the subtelomeric multigene vir superfamily.

artículo científico publicado en 2008

Plasmodium vivax epidemiology in Ethiopia 2000-2020: A systematic review and meta-analysis

artículo científico publicado en 2021

Plasmodium vivax gametocytes in the bone marrow of an acute malaria patient and changes in the erythroid miRNA profile.

artículo científico publicado en 2017

Plasmodium vivax malaria in Mali: a study from three different regions

artículo científico publicado en 2012

Plasmodium vivax spleen-dependent genes encode antigens associated with cytoadhesion and clinical protection

scientific article published on 21 May 2020

Plasmodium vivax: cloning and expression of a major blood-stage surface antigen.

artículo científico publicado en 1988

Plasmodium vivax: comparison of immunogenicity among proteins expressed in the cell-free systems of Escherichia coli and wheat germ by suspension array assays

artículo científico publicado en 2011

Postmortem characterization of patients with clinical diagnosis of Plasmodium vivax malaria: to what extent does this parasite kill?

artículo científico publicado en 2012

Pregnancy and malaria exposure are associated with changes in the B cell pool and in plasma eotaxin levels

artículo científico publicado en 2014

Production of recombinant PvDBPII, receptor binding domain of Plasmodium vivax Duffy binding protein, and evaluation of immunogenicity to identify an adjuvant formulation for vaccine development.

artículo científico publicado en 2015

Progress in imaging methods: insights gained into Plasmodium biology

artículo científico publicado en 2016

Proinflammatory responses and higher IL-10 production by T cells correlate with protection against malaria during pregnancy and delivery outcomes

artículo científico publicado en 2015

Promoter regions of Plasmodium vivax are poorly or not recognized by Plasmodium falciparum

artículo científico publicado en 2007

Proteomics study of human cord blood reticulocyte-derived exosomes

artículo científico publicado en 2018

Red blood cells derived from peripheral blood and bone marrow CD34⁺ human haematopoietic stem cells are permissive to Plasmodium parasites infection

artículo científico

Relapses contribute significantly to the risk of Plasmodium vivax infection and disease in Papua New Guinean children 1-5 years of age.

artículo científico publicado en 2012

Removal of leucocytes from Plasmodium vivax-infected blood.

artículo científico publicado en 1994

Reticulocyte-prone malaria parasites predominantly invade CD71hi immature cells: implications for the development of an in vitro culture for Plasmodium vivax.

artículo científico publicado en 2013

Second form in a segment of the merozoite surface protein 1 gene of Plasmodium vivax among isolates from Rondônia (Brazil).

artículo científico publicado en 1992

Serum-derived exosomes from non-viremic animals previously exposed to the porcine respiratory and reproductive virus contain antigenic viral proteins

artículo científico publicado en 2016

Sex-specific and blood meal-induced proteins of Anopheles gambiae midguts: analysis by two-dimensional gel electrophoresis ⬇️

artículo científico publicado en 2003

Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals

artículo científico

Size-exclusion chromatography-based enrichment of extracellular vesicles from urine samples

artículo científico publicado en 2015

Spleen rupture in a case of untreated Plasmodium vivax infection.

artículo científico publicado en 2012

Spleen-Dependent Immune Protection Elicited by CpG Adjuvanted Reticulocyte-Derived Exosomes from Malaria Infection Is Associated with Changes in T cell Subsets' Distribution

artículo científico publicado en 2016

Strain-specific spleen remodelling in Plasmodium yoelii infections in Balb/c mice facilitates adherence and spleen macrophage-clearance escape.

artículo científico publicado en 2010

Sudden spleen rupture in a Plasmodium vivax-infected patient undergoing malaria treatment.

artículo científico publicado en 2018

Talking to each other to initiate sexual differentiation.

artículo científico publicado en 2013

Targeted-pig trial on safety and immunogenicity of serum-derived extracellular vesicles enriched fractions obtained from Porcine Respiratory and Reproductive virus infections

scientific article published in Scientific Reports

The Role of Extracellular Vesicles in Modulating the Host Immune Response during Parasitic Infections

artículo científico

The machinery underlying malaria parasite virulence is conserved between rodent and human malaria parasites

artículo científico publicado en 2016

Variant genes and the spleen in Plasmodium vivax malaria.

artículo científico publicado en 2004

Variant proteins of Plasmodium vivax are not clonally expressed in natural infections.

artículo científico publicado en 2005

Lista de obras de Hernando A del Portillo Obando

A functional microengineered model of the human splenon-on-a-chip

A new computational approach redefines the subtelomeric vir superfamily of Plasmodium vivax.

A reduced risk of infection with Plasmodium vivax and clinical protection against malaria are associated with antibodies against the N terminus but not the C terminus of merozoite surface protein 1.

A superfamily of variant genes encoded in the subtelomeric region of Plasmodium vivax

Advances toward the development of an asexual blood stage MSP-1 vaccine of Plasmodium vivax.

Analysis of single-nucleotide polymorphisms in the crt-o and mdr1 genes of Plasmodium vivax among chloroquine-resistant isolates from the Brazilian Amazon region

Antigenic properties of the merozoite surface protein 1 gene of Plasmodium vivax

Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper.

Biological properties of extracellular vesicles and their physiological functions.

Characterisation of the Cdc2-related kinase 2 gene from Plasmodium knowlesi and P. berghei.

Characterization of Plasmodium vivax Proteins in Plasma-Derived Exosomes From Malaria-Infected Liver-Chimeric Humanized Mice.

Circumsporozoite gene of a Plasmodium falciparum strain from Thailand

Comparison of diagnostic methods for the detection and quantification of the four sympatric Plasmodium species in field samples from Papua New Guinea

Comparison of introns in a cdc2-homologous gene within a number of Plasmodium species.

Concise Review: Developing Best-Practice Models for the Therapeutic Use of Extracellular Vesicles.

Corrigendum: Spleen-Dependent Immune Protection Elicited by CpG Adjuvanted Reticulocyte-Derived Exosomes from Malaria Infection Is Associated with Changes in T Cell Subsets' Distribution.

EVpedia: a community web portal for extracellular vesicles research

Effect of immunosuppression in miRNAs from extracellular vesicles of colorectal cancer and their influence on the pre-metastatic niche

Evaluation of the acquired immune responses to Plasmodium vivax VIR variant antigens in individuals living in malaria-endemic areas of Brazil

Evidence for different mechanisms of chloroquine resistance in 2 Plasmodium species that cause human malaria.

Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine

Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections.

Expression and function of pvcrt-o, a Plasmodium vivax ortholog of pfcrt, in Plasmodium falciparum and Dictyostelium discoideum.

Expression levels of pvcrt-o and pvmdr-1 are associated with chloroquine resistance and severe Plasmodium vivax malaria in patients of the Brazilian Amazon.

Expression of non-TLR pattern recognition receptors in the spleen of BALB/c mice infected with Plasmodium yoelii and Plasmodium chabaudi chabaudi AS.

Extracellular vesicles in parasitic diseases

Functional analysis of Plasmodium vivax VIR proteins reveals different subcellular localizations and cytoadherence to the ICAM-1 endothelial receptor.

Genetic immunization of BALB/c mice with a plasmid bearing the gene coding for a hybrid merozoite surface protein 1-hepatitis B virus surface protein fusion protects mice against lethal Plasmodium chabaudi chabaudi PC1 infection

Heat shock induction of apoptosis in promastigotes of the unicellular organism Leishmania (Leishmania) amazonensis

Highlights of the São Paulo ISEV workshop on extracellular vesicles in cross-kingdom communication.

Human IgG responses against the N-terminal region of the Merozoite Surface Protein 1 of Plasmodium vivax

Human Splenon-on-a-chip: Design and Validation of a Microfluidic Model Resembling the Interstitial Slits and the Close/Fast and Open/Slow Microcirculations

Imaging of the spleen in malaria.

In vivo and in vitro characterization of a Plasmodium liver stage-specific promoter

Increased expression levels of the pvcrt-o and pvmdr1 genes in a patient with severe Plasmodium vivax malaria

Intravital microscopy of the spleen: quantitative analysis of parasite mobility and blood flow

Key gaps in the knowledge of Plasmodium vivax, a neglected human malaria parasite

Malaria parasites contain two identical copies of an elongation factor 1 alpha gene.

Malaria parasites lacking eef1a have a normal S/M phase yet grow more slowly due to a longer G1 phase.

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Mining the malaria transcriptome.

Molecular analysis of Plasmodium vivax relapses using the MSP1 molecule as a genetic marker.

Naturally Acquired Binding-Inhibitory Antibodies to Plasmodium vivax Duffy Binding Protein in Pregnant Women Are Associated with Higher Birth Weight in a Multicenter Study

Naturally-acquired humoral immune responses against the N- and C-termini of the Plasmodium vivax MSP1 protein in endemic regions of Brazil and Papua New Guinea using a multiplex assay

On cytoadhesion of Plasmodium vivax: raison d'être?

On the cytoadhesion of Plasmodium vivax-infected erythrocytes

Origins of sequence diversity in the malaria vaccine candidate merozoite surface protein-2 (MSP-2) in Amazonian isolates of Plasmodium falciparum.

Paucity of Plasmodium vivax mature schizonts in peripheral blood is associated with their increased cytoadhesive potential

Placental infection with Plasmodium vivax: a histopathological and molecular study

Plasma-derived extracellular vesicles from Plasmodium vivax patients signal spleen fibroblasts via NF-kB facilitating parasite cytoadherence

Plasmodium falciparum: DBL-1 var sequence analysis in field isolates from central Brazil.

Plasmodium falciparum: epidemiological studies on the circumsporozoite gene

Plasmodium falciparum: new vector with bi-directional promoter activity to stably express transgenes

Plasmodium vivax VIR Proteins Are Targets of Naturally-Acquired Antibody and T Cell Immune Responses to Malaria in Pregnant Women

Plasmodium vivax and the importance of the subtelomeric multigene vir superfamily.

Plasmodium vivax epidemiology in Ethiopia 2000-2020: A systematic review and meta-analysis

Plasmodium vivax gametocytes in the bone marrow of an acute malaria patient and changes in the erythroid miRNA profile.

Plasmodium vivax malaria in Mali: a study from three different regions

Plasmodium vivax spleen-dependent genes encode antigens associated with cytoadhesion and clinical protection

Plasmodium vivax: cloning and expression of a major blood-stage surface antigen.

Plasmodium vivax: comparison of immunogenicity among proteins expressed in the cell-free systems of Escherichia coli and wheat germ by suspension array assays

Postmortem characterization of patients with clinical diagnosis of Plasmodium vivax malaria: to what extent does this parasite kill?

Pregnancy and malaria exposure are associated with changes in the B cell pool and in plasma eotaxin levels

Production of recombinant PvDBPII, receptor binding domain of Plasmodium vivax Duffy binding protein, and evaluation of immunogenicity to identify an adjuvant formulation for vaccine development.

Progress in imaging methods: insights gained into Plasmodium biology

Proinflammatory responses and higher IL-10 production by T cells correlate with protection against malaria during pregnancy and delivery outcomes

Promoter regions of Plasmodium vivax are poorly or not recognized by Plasmodium falciparum

Proteomics study of human cord blood reticulocyte-derived exosomes

Red blood cells derived from peripheral blood and bone marrow CD34⁺ human haematopoietic stem cells are permissive to Plasmodium parasites infection

Relapses contribute significantly to the risk of Plasmodium vivax infection and disease in Papua New Guinean children 1-5 years of age.

Removal of leucocytes from Plasmodium vivax-infected blood.

Reticulocyte-prone malaria parasites predominantly invade CD71hi immature cells: implications for the development of an in vitro culture for Plasmodium vivax.

Second form in a segment of the merozoite surface protein 1 gene of Plasmodium vivax among isolates from Rondônia (Brazil).

Serum-derived exosomes from non-viremic animals previously exposed to the porcine respiratory and reproductive virus contain antigenic viral proteins

Sex-specific and blood meal-induced proteins of Anopheles gambiae midguts: analysis by two-dimensional gel electrophoresis ⬇️

Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals

Size-exclusion chromatography-based enrichment of extracellular vesicles from urine samples

Spleen rupture in a case of untreated Plasmodium vivax infection.

Spleen-Dependent Immune Protection Elicited by CpG Adjuvanted Reticulocyte-Derived Exosomes from Malaria Infection Is Associated with Changes in T cell Subsets' Distribution