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A257T linker region mutant of T7 helicase-primase protein is defective in DNA loading and rescued by T7 DNA polymerase

artículo científico publicado en 2011

ATP-induced helicase slippage reveals highly coordinated subunits.

artículo científico

Dynamics of Staphylococcus aureus Cas9 in DNA target Association and Dissociation

artículo científico publicado en 2020

Helicase promotes replication re-initiation from an RNA transcript.

artículo científico publicado en 2018

Human RPA activates BLM's bidirectional DNA unwinding from a nick

artículo científico publicado en 2020

In Vitro Biochemical Assays using Biotin Labels to Study Protein-Nucleic Acid Interactions

artículo científico publicado en 2019

MOV10L1 Binds RNA G-Quadruplex in a Structure-Specific Manner and Resolves It More Efficiently Than MOV10

scientific article published on 15 June 2019

Rescuing Replication from Barriers: Mechanistic Insights from Single-Molecule Studies

scientific article published on 30 April 2019

Single-Molecule Optical-Trapping Techniques to Study Molecular Mechanisms of a Replisome.

artículo científico publicado en 2016

Single-molecule perspectives on helicase mechanisms and functions.

artículo científico publicado en 2015

Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly

scientific article published on 01 May 2019

T7 replisome directly overcomes DNA damage

artículo científico publicado en 2015

The HRDC domain oppositely modulates the unwinding activity of E. coli RecQ helicase on duplex DNA and G-quadruplex

artículo científico publicado en 2020

The nuclear localization sequence mediates hnRNPA1 amyloid fibril formation revealed by cryoEM structure

scientific article published on 11 December 2020

The post-PAM interaction of RNA-guided spCas9 with DNA dictates its target binding and dissociation

artículo científico publicado en 2019