Lista de obras - Sadanandan E Velu - Dominio Público Uruguay

A Novel Marine Natural Product Derived Pyrroloiminoquinone with Potent Activity against Skin Cancer Cells

artículo científico publicado en 2019

A facile synthesis of bispyrroloquinone and bispyrroloiminoquinone ring system of marine alkaloids

artículo científico publicado en 2009

A novel class of mitochondria-targeted soft electrophiles modifies mitochondrial proteins and inhibits mitochondrial metabolism in breast cancer cells through redox mechanisms.

artículo científico publicado en 2015

A novel synthetic iminoquinone, BA-TPQ, as an anti-breast cancer agent: in vitro and in vivo activity and mechanisms of action.

artículo científico publicado en 2009

An Expedient Synthesis of Murrayaquinone A via a Novel Oxidative Free Radical Reaction

artículo científico publicado en 2018

Analogs of the marine alkaloid makaluvamines: synthesis, topoisomerase II inhibition, and anticancer activity.

artículo científico publicado en 2007

Antibacterial and Antibiofilm Activities of Makaluvamine Analogs

artículo científico publicado en 2014

Attenuation of nonsense-mediated mRNA decay enhances in vivo nonsense suppression

artículo científico publicado en 2013

Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer

artículo científico publicado en 2018

Channel Gating Regulation by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) First Cytosolic Loop

artículo científico publicado en 2015

Conjugate addition reactions of alpha-aminoalkylcuprates with alpha, beta-alkenyl-, alpha,beta-alkynyl-, alpha,beta-beta,gamma-allenyl-, and alpha,beta-gamma,delta-dienyl carboxylic acid derivatives, nitriles, and sulfoxides

artículo científico publicado en 2000

Cyanobacterial Metabolite Calothrixins: Recent Advances in Synthesis and Biological Evaluation

artículo científico publicado en 2016

Development and validation of an HPLC method for quantitation of BA‐TPQ, a novel iminoquinone anticancer agent, and an initial pharmacokinetic study in mice ⬇️

artículo científico publicado el 15 de septiembre de 2010

Discovery and Characterization of Dual Inhibitors of MDM2 and NFAT1 for Pancreatic Cancer Therapy

scientific article published on 14 September 2018

Discovery and evaluation of nNav1.5 sodium channel blockers with potent cell invasion inhibitory activity in breast cancer cells.

artículo científico publicado en 2018

Elevated levels of NO are localized to distal airways in asthma

artículo científico publicado en 2011

Experimental Therapy of Ovarian Cancer with Synthetic Makaluvamine Analog: In Vitro and In Vivo Anticancer Activity and Molecular Mechanisms of Action ⬇️

artículo científico publicado el 6 de junio de 2011

FBA-TPQ, a novel marine-derived compound as experimental therapy for prostate cancer.

artículo científico publicado en 2009

Highly efficient delivery of potent anticancer iminoquinone derivative by multilayer hydrogel cubes

artículo científico publicado en 2017

Honokiol inhibits the growth of head and neck squamous cell carcinoma by targeting epidermal growth factor receptor

artículo científico publicado en 2015

Hydroxychalcone inhibitors of Streptococcus mutans glucosyl transferases and biofilms as potential anticaries agents.

artículo científico publicado en 2016

Identification of the ZAK-MKK4-JNK-TGFβ signaling pathway as a molecular target for novel synthetic iminoquinone anticancer compound BA-TPQ.

artículo científico publicado en 2013

In vitro and in vivo anticancer activity of novel synthetic makaluvamine analogues.

artículo científico publicado en 2009

Inhibition of Streptococcus mutans Biofilms by the Natural Stilbene Piceatannol Through the Inhibition of Glucosyltransferases

scientific article published on 30 July 2018

L-2-Hydroxyglutarate: an epigenetic modifier and putative oncometabolite in renal cancer.

artículo científico publicado en 2014

MDM2-NFAT1 dual inhibitor, MA242: Effective against hepatocellular carcinoma, independent of p53

scientific article published on 07 June 2019

Mini-review: bmx kinase inhibitors for cancer therapy.

artículo científico publicado en 2013

Mitochondrial thiol modification by a targeted electrophile inhibits metabolism in breast adenocarcinoma cells by inhibiting enzyme activity and protein levels.

artículo científico publicado en 2016

New small-molecule inhibitors of dihydrofolate reductase inhibit Streptococcus mutans.

artículo científico publicado en 2015

Nonsense-mediated decay controls the reactivation of the oncogenic herpesviruses EBV and KSHV

artículo científico publicado en 2021

Preclinical pharmacology of BA-TPQ, a novel synthetic iminoquinone anticancer agent.

artículo científico publicado en 2010

Pyrrolidinobenzoic acid inhibitors of influenza virus neuraminidase: modifications of essential pyrrolidinone ring substituents.

artículo científico publicado en 2003

SF3B1 homeostasis is critical for survival and therapeutic response in T cell leukemia

artículo científico publicado en 2022

Structure-Based Discovery of Small Molecule Inhibitors of Cariogenic Virulence

artículo científico publicado en 2017

Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function

artículo científico publicado en 2008

Synthesis and in vitro anti-lung cancer activity of novel 1, 3, 4, 8-tetrahydropyrrolo [4, 3, 2-de]quinolin-8(1H)-one alkaloid analogs.

artículo científico publicado en 2009

Synthesis and structure activity relationship studies of novel Staphylococcus aureus Sortase A inhibitors.

artículo científico publicado en 2010

Synthesis of biotin-tagged chemical cross-linkers and their applications for mass spectrometry.

artículo científico publicado en 2009

Synthetic Makaluvamine Analogs Decrease c-Kit Expression and Are Cytotoxic to Neuroendocrine Tumor Cells

artículo científico publicado en 2020

Tethered dimer inhibitors of NAD synthetase: parallel synthesis of an aryl-substituted SAR library.

artículo científico publicado en 2005

Tethered dimers as NAD synthetase inhibitors with antibacterial activity.

artículo científico publicado en 2003

Total Synthesis of Calothrixins A and B via Oxidative Radical Reaction of Cyclohexenone with Aminophenanthridinedione.

artículo científico publicado en 2014

Lista de obras de Sadanandan E Velu

A Novel Marine Natural Product Derived Pyrroloiminoquinone with Potent Activity against Skin Cancer Cells

A facile synthesis of bispyrroloquinone and bispyrroloiminoquinone ring system of marine alkaloids

A novel class of mitochondria-targeted soft electrophiles modifies mitochondrial proteins and inhibits mitochondrial metabolism in breast cancer cells through redox mechanisms.

A novel synthetic iminoquinone, BA-TPQ, as an anti-breast cancer agent: in vitro and in vivo activity and mechanisms of action.

An Expedient Synthesis of Murrayaquinone A via a Novel Oxidative Free Radical Reaction

Analogs of the marine alkaloid makaluvamines: synthesis, topoisomerase II inhibition, and anticancer activity.

Antibacterial and Antibiofilm Activities of Makaluvamine Analogs

Attenuation of nonsense-mediated mRNA decay enhances in vivo nonsense suppression

Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer

Channel Gating Regulation by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) First Cytosolic Loop

Conjugate addition reactions of alpha-aminoalkylcuprates with alpha, beta-alkenyl-, alpha,beta-alkynyl-, alpha,beta-beta,gamma-allenyl-, and alpha,beta-gamma,delta-dienyl carboxylic acid derivatives, nitriles, and sulfoxides

Cyanobacterial Metabolite Calothrixins: Recent Advances in Synthesis and Biological Evaluation

Development and validation of an HPLC method for quantitation of BA‐TPQ, a novel iminoquinone anticancer agent, and an initial pharmacokinetic study in mice ⬇️

Discovery and Characterization of Dual Inhibitors of MDM2 and NFAT1 for Pancreatic Cancer Therapy

Discovery and evaluation of nNav1.5 sodium channel blockers with potent cell invasion inhibitory activity in breast cancer cells.

Elevated levels of NO are localized to distal airways in asthma

Experimental Therapy of Ovarian Cancer with Synthetic Makaluvamine Analog: In Vitro and In Vivo Anticancer Activity and Molecular Mechanisms of Action ⬇️

FBA-TPQ, a novel marine-derived compound as experimental therapy for prostate cancer.

Highly efficient delivery of potent anticancer iminoquinone derivative by multilayer hydrogel cubes

Honokiol inhibits the growth of head and neck squamous cell carcinoma by targeting epidermal growth factor receptor

Hydroxychalcone inhibitors of Streptococcus mutans glucosyl transferases and biofilms as potential anticaries agents.

Identification of the ZAK-MKK4-JNK-TGFβ signaling pathway as a molecular target for novel synthetic iminoquinone anticancer compound BA-TPQ.

In vitro and in vivo anticancer activity of novel synthetic makaluvamine analogues.

Inhibition of Streptococcus mutans Biofilms by the Natural Stilbene Piceatannol Through the Inhibition of Glucosyltransferases

L-2-Hydroxyglutarate: an epigenetic modifier and putative oncometabolite in renal cancer.

MDM2-NFAT1 dual inhibitor, MA242: Effective against hepatocellular carcinoma, independent of p53

Mini-review: bmx kinase inhibitors for cancer therapy.

Mitochondrial thiol modification by a targeted electrophile inhibits metabolism in breast adenocarcinoma cells by inhibiting enzyme activity and protein levels.

New small-molecule inhibitors of dihydrofolate reductase inhibit Streptococcus mutans.

Nonsense-mediated decay controls the reactivation of the oncogenic herpesviruses EBV and KSHV

Preclinical pharmacology of BA-TPQ, a novel synthetic iminoquinone anticancer agent.

Pyrrolidinobenzoic acid inhibitors of influenza virus neuraminidase: modifications of essential pyrrolidinone ring substituents.

SF3B1 homeostasis is critical for survival and therapeutic response in T cell leukemia

Structure-Based Discovery of Small Molecule Inhibitors of Cariogenic Virulence

Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function

Synthesis and in vitro anti-lung cancer activity of novel 1, 3, 4, 8-tetrahydropyrrolo [4, 3, 2-de]quinolin-8(1H)-one alkaloid analogs.

Synthesis and structure activity relationship studies of novel Staphylococcus aureus Sortase A inhibitors.

Synthesis of biotin-tagged chemical cross-linkers and their applications for mass spectrometry.

Synthetic Makaluvamine Analogs Decrease c-Kit Expression and Are Cytotoxic to Neuroendocrine Tumor Cells

Tethered dimer inhibitors of NAD synthetase: parallel synthesis of an aryl-substituted SAR library.

Tethered dimers as NAD synthetase inhibitors with antibacterial activity.

Total Synthesis of Calothrixins A and B via Oxidative Radical Reaction of Cyclohexenone with Aminophenanthridinedione.