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Lista de obras de Harikrishna Nakshatri

2-methoxyestradiol inhibits the anaphase-promoting complex and protein translation in human breast cancer cells

artículo científico

A Spectrum Graph-Based Protein Sequence Filtering Algorithm for Proteoform Identification by Top-Down Mass Spectrometry.

artículo científico publicado en 2017

A large, consistent plasma proteomics data set from prospectively collected breast cancer patient and healthy volunteer samples

artículo científico publicado en 2011

A system for detecting high impact-low frequency mutations in primary tumors and metastases

artículo científico publicado en 2017

A water soluble parthenolide analog suppresses in vivo tumor growth of two tobacco-associated cancers, lung and bladder cancer, by targeting NF-κB and generating reactive oxygen species.

artículo científico publicado en 2011

A water-soluble parthenolide analogue suppresses in vivo prostate cancer growth by targeting NFkappaB and generating reactive oxygen species.

artículo científico publicado en 2010

AKT alters genome-wide estrogen receptor alpha binding and impacts estrogen signaling in breast cancer.

artículo científico publicado en 2008

ANTXR1, a stem cell-enriched functional biomarker, connects collagen signaling to cancer stem-like cells and metastasis in breast cancer.

artículo científico publicado en 2013

Aberrant epigenetic and transcriptional events associated with breast cancer risk

artículo científico publicado en 2022

Activity and enhancer binding factors for BK virus regulatory elements in differentiating embryonal carcinoma cells.

artículo científico publicado en 1991

Activity and enhancer binding factors for JC virus regulatory elements in differentiating embryonal carcinoma cells

artículo científico publicado en 1990

Aged Breast Extracellular Matrix Drives Mammary Epithelial Cells to an Invasive and Cancer-Like Phenotype

artículo científico publicado en 2021

Amplified in breast cancer 1 expression in breast cancer.

artículo científico publicado en 2008

An Effective Epigenetic-PARP inhibitor Combination Therapy for Breast and Ovarian Cancers Independent of BRCA-mutations.

artículo científico publicado en 2018

Angiopoietin-2 mediates blood-brain barrier impairment and colonization of triple-negative breast cancer cells in brain.

artículo científico publicado en 2014

Antimyeloma effects of a sesquiterpene lactone parthenolide.

artículo científico publicado en 2008

Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase.

artículo científico publicado en 2004

Antitumor properties of novel sesquiterpene lactone analogs as NFκB inhibitors that bind to the IKKβ ubiquitin-like domain (ULD)

artículo científico

Attraction and Compaction of Migratory Breast Cancer Cells by Bone Matrix Proteins through Tumor-Osteocyte Interactions.

artículo científico publicado en 2018

Binding and activation of the human aldehyde dehydrogenase 2 promoter by hepatocyte nuclear factor 4

artículo científico publicado en 1998

Biomarkers for breast cancer stem cells: the challenges ahead

artículo científico

Breast Heterogeneity: Obstacles to Developing Universal Biomarkers of Breast Cancer Initiation and Progression

scientific article published on 17 April 2020

Breast cancer cell detection and characterization from breast milk-derived cells

scientific article published on 15 September 2020

Breast cancer stem cells and intrinsic subtypes: controversies rage on.

scientific article published on January 2009

Breast-cancer stem cells-beyond semantics

artículo científico

CD44+/CD24- breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis

artículo científico publicado en 2006

CNI-1493 inhibits monocyte/macrophage tumor necrosis factor by suppression of translation efficiency.

artículo científico publicado en 1996

Cancer affects microRNA expression, release, and function in cardiac and skeletal muscle

artículo científico publicado en 2014

Cancer cell-derived interleukin 1alpha contributes to autocrine and paracrine induction of pro-metastatic genes in breast cancer

artículo científico publicado en 2000

Cell competition and tumor heterogeneity

scientific article published on 09 September 2019

Cloning of BRAK, a novel divergent CXC chemokine preferentially expressed in normal versus malignant cells

artículo científico publicado en 1999

Death effector domain-containing protein induces vulnerability to cell cycle inhibition in triple-negative breast cancer

artículo científico publicado en 2019

Delivery of nanoparticles to brain metastases of breast cancer using a cellular Trojan horse.

artículo científico publicado en 2012

Dependence receptor UNC5A restricts luminal to basal breast cancer plasticity and metastasis.

artículo científico publicado en 2018

Differential effect of Nonidet P40 on DNA binding of transcription factors.

artículo científico publicado en 1997

Differential effect of anti-apoptotic genes Bcl-xL and c-FLIP on sensitivity of MCF-7 breast cancer cells to paclitaxel and docetaxel

artículo científico publicado en 2005

Differential whole-cell extract preparation and electrophoretic mobility shift assay to evaluate the effect of tyrosine phosphatases on DNA binding activity of transcription factors

artículo científico publicado en 1996

Distinct Effects of Adipose-Derived Stem Cells and Adipocytes on Normal and Cancer Cell Hierarchy.

artículo científico publicado en 2016

Dual TGFβ/BMP Pathway Inhibition Enables Expansion and Characterization of Multiple Epithelial Cell Types of the Normal and Cancerous Breast

scientific article published on 16 April 2019

Effect of celecoxib and novel agent LC-1 in a hamster model of lung cancer.

artículo científico publicado en 2007

Effects of HIV protease inhibitor ritonavir on Akt-regulated cell proliferation in breast cancer

artículo científico publicado en 2006

Effects of a checkpoint kinase inhibitor, AZD7762, on tumor suppression and bone remodeling.

artículo científico publicado en 2018

Enhanced peritoneal ovarian tumor dissemination by tissue transglutaminase

artículo científico publicado en 2007

Epithelial-to-mesenchymal transition and ovarian tumor progression induced by tissue transglutaminase

artículo científico publicado en 2009

Essential Components of Cancer Education

artículo científico publicado en 2015

Estradiol-regulated microRNAs control estradiol response in breast cancer cells

artículo científico publicado en 2009

Ethnicity-Dependent and -Independent Heterogeneity in Healthy Normal Breast Hierarchy Impacts Tumor Characterization.

artículo científico publicado en 2015

Expression of Forkhead-box protein A1, a marker of luminal A type breast cancer, parallels low Oncotype DX 21-gene recurrence scores.

artículo científico publicado en 2009

FOXA1 Expression in Breast Cancer Correlation with Luminal Subtype A and Survival

artículo científico publicado en 2007

FOXA1 as a therapeutic target for breast cancer

artículo científico publicado en 2007

FOXA1 in breast cancer

artículo científico publicado en 2009

FOXA1 is an independent prognostic marker for ER-positive breast cancer.

artículo científico publicado en 2011

Flower isoforms promote competitive growth in cancer

artículo científico publicado en 2019

Forkhead box A1 expression in breast cancer is associated with luminal subtype and good prognosis.

artículo científico publicado en 2007

Fusion AML1 transcript in a radiation-associated leukemia results in a truncated inhibitory AML1 protein

artículo científico publicado en 2001

Genetic Ancestry-dependent Differences in Breast Cancer-induced Field Defects in the Tumor-adjacent Normal Breast

scientific article published on 04 February 2019

HOXB13 mediates tamoxifen resistance and invasiveness in human breast cancer by suppressing ERα and inducing IL-6 expression

artículo científico publicado en 2013

HOXB7 Is an ERα Cofactor in the Activation of HER2 and Multiple ER Target Genes Leading to Endocrine Resistance

artículo científico publicado en 2015

High-level expression of forkhead-box protein A1 in metastatic prostate cancer

artículo científico publicado en 2011

ITF2 is a target of CXCR4 in MDA-MB-231 breast cancer cells and is associated with reduced survival in estrogen receptor-negative breast cancer

artículo científico publicado en 2010

Identification of FDA-approved drugs targeting breast cancer stem cells along with biomarkers of sensitivity.

artículo científico publicado en 2013

Identification of signal transduction pathways involved in constitutive NF-kappaB activation in breast cancer cells

artículo científico publicado en 2002

Identity profiling of cell surface markers by multiplex gold nanorod probes

artículo científico publicado en 2007

In vivo modeling of metastatic human high-grade serous ovarian cancer in mice

artículo científico publicado en 2020

Individualized Breast Cancer Characterization through Single-Cell Analysis of Tumor and Adjacent Normal Cells.

artículo científico publicado en 2017

Inflammation-associated microRNA changes in circulating exosomes of heart failure patients

artículo científico publicado en 2017

Inhibiting checkpoint kinase 1 protects bone from bone resorption by mammary tumor in a mouse model.

artículo científico publicado en 2018

Inhibiting proteasomal proteolysis sustains estrogen receptor-alpha activation.

artículo científico publicado en 2004

Inhibitory Effects of Dopamine Receptor D1 Agonist on Mammary Tumor and Bone Metastasis

artículo científico publicado en 2017

Interferon-γ signaling is associated with BRCA1 loss-of-function mutations in high grade serous ovarian cancer

scientific article published on 06 December 2019

Interleukin-1 alpha promotes tumor growth and cachexia in MCF-7 xenograft model of breast cancer.

artículo científico publicado en 2003

Interplay between estrogen receptor and AKT in estradiol-induced alternative splicing

artículo científico publicado en 2013

Intrinsic subtype-associated changes in the plasma proteome in breast cancer.

artículo científico publicado en 2009

Isolation of retinoic acid-repressed genes from P19 embryonal carcinoma cells.

artículo científico publicado en 1996

Loss of ERα and FOXA1 expression in a progression model of luminal type breast cancer: insights from PyMT transgenic mouse model.

artículo científico publicado en 2010

MMB triazole analogs are potent NF-κB inhibitors and anti-cancer agents against both hematological and solid tumor cells

scientific article published on 10 August 2018

MOZ and MOZ-CBP cooperate with NF-kappaB to activate transcription from NF-kappaB-dependent promoters.

artículo científico

Molecular Insights of Pathways Resulting from Two Common PIK3CA Mutations in Breast Cancer.

artículo científico publicado en 2016

Mouse retinoic acid receptor alpha 2 isoform is transcribed from a promoter that contains a retinoic acid response element

artículo científico publicado el 15 de noviembre de 1991

Multiple parameters determine the specificity of transcriptional response by nuclear receptors HNF-4, ARP-1, PPAR, RAR and RXR through common response elements.

artículo científico publicado en 1998

Mutational landscape of RNA-binding proteins in human cancers

artículo científico publicado en 2017

NF-kappaB activation and interleukin 6 production in fibroblasts by estrogen receptor-negative breast cancer cell-derived interleukin 1alpha.

artículo científico publicado en 1998

NF-kappaB and breast cancer

artículo científico publicado en 2002

NF-kappaB inhibition in human hepatocellular carcinoma and its potential as adjunct to sorafenib based therapy.

artículo científico publicado en 2009

NF-kappaB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4

artículo científico publicado en 2003

NF-κB-dependent and -independent epigenetic modulation using the novel anti-cancer agent DMAPT

artículo científico publicado en 2015

Negative regulation of MHC class II gene expression by CXCR4.

artículo científico publicado en 2006

Negative regulation of chemokine receptor CXCR4 by tumor suppressor p53 in breast cancer cells: implications of p53 mutation or isoform expression on breast cancer cell invasion.

artículo científico publicado en 2006

Negative regulation of transactivation function but not DNA binding of NF-kappaB and AP-1 by IkappaBbeta1 in breast cancer cells

artículo científico publicado en 1999

Normal Breast-Derived Epithelial Cells with Luminal and Intrinsic Subtype-Enriched Gene Expression Document Interindividual Differences in Their Differentiation Cascade

artículo científico publicado en 2018

Nuclear factor-kappaB is constitutively activated in prostate cancer in vitro and is overexpressed in prostatic intraepithelial neoplasia and adenocarcinoma of the prostate.

artículo científico publicado en 2004

Obesity potentiates the growth and dissemination of pancreatic cancer

artículo científico publicado en 2009

Oestrogen-receptor-positive breast cancer: towards bridging histopathological and molecular classifications.

artículo científico publicado en 2008

Organ-specific adaptive signaling pathway activation in metastatic breast cancer cells

artículo científico publicado en 2015

Osteocyte-Driven Downregulation of Snail Restrains Effects of Drd2 Inhibitors on Mammary Tumor Cells

artículo científico publicado en 2018

PROGgene: gene expression based survival analysis web application for multiple cancers.

artículo científico publicado en 2013

PROGgeneV2: enhancements on the existing database

artículo científico publicado en 2014

PROGmiR: a tool for identifying prognostic miRNA biomarkers in multiple cancers using publicly available data

artículo científico publicado en 2012

Paclitaxel sensitivity of breast cancer cells with constitutively active NF-kappaB is enhanced by IkappaBalpha super-repressor and parthenolide

scientific article published on 01 August 2000

Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-kappa B pathway in pancreatic carcinoma cells.

artículo científico publicado en 2005

Parthenolide sensitizes cells to X-ray-induced cell killing through inhibition of NF-kappaB and split-dose repair.

artículo científico publicado en 2007

Persistent upregulation of U6:SNORD44 small RNA ratio in the serum of breast cancer patients

artículo científico publicado en 2011

Pharmacological Dual Inhibition of Tumor and Tumor-Induced Functional Limitations in a Transgenic Model of Breast Cancer

artículo científico publicado en 2017

Phase I dose escalation trial of feverfew with standardized doses of parthenolide in patients with cancer.

artículo científico publicado en 2004

Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance

artículo científico publicado en 2001

Phosphoinositol phosphatase SHIP2 promotes cancer development and metastasis coupled with alterations in EGF receptor turnover.

artículo científico publicado en 2007

Prognosis of hormone-dependent breast cancers: implications of the presence of dysfunctional transcriptional networks activated by insulin via the immune transcription factor T-bet

artículo científico publicado en 2010

Prognostic impact of ALDH1 in breast cancer: a story of stem cells and tumor microenvironment.

artículo científico publicado en 2009

Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors

artículo científico publicado en 1992

Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently

artículo científico publicado en 1992

Radiation resistance in breast cancer: are CD44+/CD24-/proteosome low/PKH26+ cells to blame?

artículo científico publicado en 2010

RareVar: A Framework for Detecting Low-Frequency Single-Nucleotide Variants

artículo científico publicado en 2017

Reduction in Migratory Phenotype in a Metastasized Breast Cancer Cell Line via Downregulation of S100A4 and GRM3.

artículo científico publicado en 2017

Repression of transforming-growth-factor-beta-mediated transcription by nuclear factor kappaB.

artículo científico

Restoring chemotherapy and hormone therapy sensitivity by parthenolide in a xenograft hormone refractory prostate cancer model

artículo científico publicado en 2006

Retinoic acid signal transduction pathways.

artículo científico publicado en 1993

Role of AKT isotypes in breast cancer

artículo científico publicado en 2013

SLUG/SNAI2 and tumor necrosis factor generate breast cells with CD44+/CD24- phenotype.

artículo científico publicado en 2010

Skeletal loading regulates breast cancer-associated osteolysis in a loading intensity-dependent fashion

scientific article published on 14 February 2020

Stage and tissue-specific expression of the alcohol dehydrogenase 1 (Adh-1) gene during mouse development.

artículo científico publicado en 1994

Statistical modeling for sensitive detection of low-frequency single nucleotide variants

artículo científico publicado en 2016

Striatin-3 gamma inhibits estrogen receptor activity by recruiting a protein phosphatase

artículo científico publicado en 2008

Subcellular localization of activated AKT in estrogen receptor- and progesterone receptor-expressing breast cancers: potential clinical implications

artículo científico publicado en 2010

Suppression of pancreatic tumor growth by combination chemotherapy with sulindac and LC-1 is associated with cyclin D1 inhibition in vivo.

artículo científico publicado en 2007

Systemic Actions of Breast Cancer Facilitate Functional Limitations

scientific article published on 13 January 2020

TFAP2C expression in breast cancer: correlation with overall survival beyond 10 years of initial diagnosis.

artículo científico publicado en 2015

TNFalpha resistance in MCF-7 breast cancer cells is associated with altered subcellular localization of p21CIP1 and p27KIP1

artículo científico publicado en 2005

The first 124 nucleotides of the E7 coding sequences of HPV16 can render the HPV11 genome transformation competent

artículo científico publicado en 1992

The macrophage inhibitory cytokine integrates AKT/PKB and MAP kinase signaling pathways in breast cancer cells

artículo científico publicado en 2005

The mushroom Ganoderma lucidum suppresses breast-to-lung cancer metastasis through the inhibition of pro-invasive genes

artículo científico publicado en 2014

The orphan receptor COUP-TFII regulates G2/M progression of breast cancer cells by modulating the expression/activity of p21(WAF1/CIP1), cyclin D1, and cdk2

scientific article published on 01 April 2000

The p160 family coactivators regulate breast cancer cell proliferation and invasion through autocrine/paracrine activity of SDF-1alpha/CXCL12.

artículo científico publicado en 2005

The platelet-derived growth factor receptor alpha is destabilized by geldanamycins in cancer cells.

artículo científico publicado en 2006

The sesquiterpene lactone parthenolide in combination with docetaxel reduces metastasis and improves survival in a xenograft model of breast cancer.

artículo científico publicado en 2005

Tissue transglutaminase protects epithelial ovarian cancer cells from cisplatin-induced apoptosis by promoting cell survival signaling

artículo científico publicado en 2008

Tumor collection/processing under physioxia uncovers highly relevant signaling networks and drug sensitivity

artículo científico publicado en 2022

Tumour necrosis factor and PI3-kinase control oestrogen receptor alpha protein level and its transrepression function

artículo científico publicado en 2004

Ubiquitous and cell-type-specific protein interactions with human papillomavirus type 16 and type 18 enhancers

artículo científico publicado en 1990

Virtual screening targeting the urokinase receptor, biochemical and cell-based studies, synthesis, pharmacokinetic characterization, and effect on breast tumor metastasis

artículo científico publicado en 2011

regSNPs-ASB: A Computational Framework for Identifying Allele-Specific Transcription Factor Binding From ATAC-seq Data

artículo científico publicado en 2020