Lista de obras - Karen E. Pollok - Dominio Público Uruguay

3552 Advancing Glioblastoma (GBM) drug regimen development to support combination therapy through integrated PKPD modeling and simulation-based predictions

A heterobivalent ligand inhibits mast cell degranulation via selective inhibition of allergen-IgE interactions in vivo

artículo científico publicado en 2014

A novel competitive repopulation strategy to quantitate engraftment of ex vivo manipulated murine marrow cells in submyeloablated hosts

artículo científico publicado en 2008

A theoretically optimized method for cord blood stem cell cryopreservation

artículo científico publicado en 2003

ATPS-75TARGETING THE Mdm2-Akt SIGNALING NETWORK IN COMBINATION WITH TEMOZOLOMIDE IMPROVES EFFICACY IN ECTOPIC AND ORTHOTOPIC PATIENT-DERIVED GLIOBLASTOMA XENOGRAFT MODELS.

artículo científico publicado en 2015

Acridine Orange as a Novel Photosensitizer for Photodynamic Therapy in Glioblastoma

artículo científico publicado en 2018

Activation of death-associated protein kinase in human peritumoral tissue: A potential therapeutic target

artículo científico publicado en 2015

Application of polychromatic flow cytometry to identify novel subsets of circulating cells with angiogenic potential

artículo científico publicado en 2010

Chemotherapeutic selectivity conferred by selenium: a role for p53-dependent DNA repair

artículo científico publicado en 2007

Combination therapy in a xenograft model of glioblastoma: enhancement of the antitumor activity of temozolomide by an MDM2 antagonist

artículo científico publicado en 2016

Comparison of three retroviral vector systems for transduction of nonobese diabetic/severe combined immunodeficiency mice repopulating human CD34+ cord blood cells.

artículo científico publicado en 2003

Design, synthesis, and evaluation of curcumin-derived arylheptanoids for glioblastoma and neuroblastoma cytotoxicity

artículo científico publicado en 2013

Differential Secondary Reconstitution of In Vivo-Selected Human SCID-Repopulating Cells in NOD/SCID versus NOD/SCID/γ chain Mice

artículo científico publicado en 2010

Dual PI3K and Wnt pathway inhibition is a synergistic combination against triple negative breast cancer

artículo científico publicado en 2017

ET-25THERAPEUTIC MODULATION OF MDM2 IN NEUROBLASTOMA

artículo científico publicado en 2014

Emerging targets for glioblastoma stem cell therapy

artículo científico publicado en 2015

Enhanced anticancer properties of lomustine in conjunction with docosahexaenoic acid in glioblastoma cell lines.

artículo científico publicado en 2014

Enhanced homing and engraftment of fresh but not ex vivo cultured murine marrow cells in submyeloablated hosts following CD26 inhibition by Diprotin A

artículo científico publicado en 2009

Evaluation of plasmid DNA removal from lentiviral vectors by benzonase treatment

artículo científico publicado en 2004

Exploring a structural protein-drug interactome for new therapeutics in lung cancer

artículo científico publicado en 2014

G2 cell cycle arrest and cyclophilin A in lentiviral gene transfer

artículo científico publicado en 2006

Gene Co-Expression Networks Restructured Gene Fusion in Rhabdomyosarcoma Cancers

scientific article published on 30 August 2019

Generation of Stable Vector-Producing Cells for Retroviral Vectors

artículo científico publicado en 2008

Glioblastoma stem cells (GSCs) epigenetic plasticity and interconversion between differentiated non-GSCs and GSCs.

artículo científico publicado en 2015

Hematopoietic expression of O(6)-methylguanine DNA methyltransferase-P140K allows intensive treatment of human glioma xenografts with combination O(6)-benzylguanine and 1,3-bis-(2-chloroethyl)-1-nitrosourea

artículo científico publicado en 2003

Human proangiogenic circulating hematopoietic stem and progenitor cells promote tumor growth in an orthotopic melanoma xenograft model

artículo científico publicado en 2013

Humanized Bone Marrow Mouse Model as a Preclinical Tool to Assess Therapy-Mediated Hematotoxicity ⬇️

artículo científico publicado el 12 de abril de 2011

Hypoxia-Inducible Factor-1α Regulates CD55 in Airway Epithelium

artículo científico publicado en 2016

Identification and Characterization of New Chemical Entities Targeting Apurinic/Apyrimidinic Endonuclease 1 for the Prevention of Chemotherapy-Induced Peripheral Neuropathy

artículo científico publicado en 2016

Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood

artículo científico publicado en 2004

Identification of parameters required for efficient lentiviral vector transduction and engraftment of human cord blood CD34(+) NOD/SCID-repopulating cells

artículo científico publicado en 2008

Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growth

artículo científico publicado en 2011

In Vivo Measurements of Tumor Metabolism and Growth after Administration of Enzastaurin Using Small Animal FDG Positron Emission Tomography

artículo científico publicado en 2009

In vivo effects of myeloablative alkylator therapy on survival and differentiation of MGMTP140K-transduced human G-CSF-mobilized peripheral blood cells

artículo científico publicado en 2006

In vivo protection of hematopoietic cells from alkylator-mediated DNA damage

artículo científico publicado en 2003

In vivo selection of hematopoietic stem cells transduced at a low multiplicity-of-infection with a foamy viral MGMT(P140K) vector

artículo científico publicado en 2008

In vivo selection of human hematopoietic cells in a xenograft model using combined pharmacologic and genetic manipulations

artículo científico publicado en 2003

Inhibition of CD26 in human cord blood CD34+ cells enhances their engraftment of nonobese diabetic/severe combined immunodeficiency mice

scientific article published on 01 June 2007

Integration of genomic copy number variations and chemotherapy-response biomarkers in pediatric sarcoma

Involvement of platelet-activating factor in ultraviolet B-induced hyperalgesia

artículo científico publicado en 2008

Lentiviral vectors pseudotyped with glycoproteins from Ross River and vesicular stomatitis viruses: variable transduction related to cell type and culture conditions

artículo científico publicado en 2005

Letrozole targets the Human ether-a-go-go-related gene (HERG) potassium current in glioblastoma

artículo científico publicado en 2020

Longitudinal Bioluminescence Imaging of Primary Versus Abdominal Metastatic Tumor Growth in Orthotopic Pancreatic Tumor Models in NSG Mice

artículo científico publicado en 2015

Melanoma LAMP-2C Modulates Tumor Growth and Autophagy

Mesenchymal stem/progenitor cells promote the reconstitution of exogenous hematopoietic stem cells in Fancg-/- mice in vivo

artículo científico publicado en 2009

Mitochondrial targeting of human O6-methylguanine DNA methyltransferase protects against cell killing by chemotherapeutic alkylating agents

artículo científico publicado en 2005

Multimodality imaging methods for assessing retinoblastoma orthotopic xenograft growth and development

artículo científico publicado en 2014

Observations on spontaneous tumor formation in mice overexpressing mitotic kinesin Kif14

scientific article published in Scientific Reports

PET imaging and optical imaging with D-luciferin [11C]methyl ester and D-luciferin [11C]methyl ether of luciferase gene expression in tumor xenografts of living mice

artículo científico publicado en 2005

PTEN and p53 are required for hypoxia induced expression of maspin in glioblastoma cells

artículo científico publicado en 2009

Peripheral blood biomarkers of solid tumor angiogenesis in dogs: a polychromatic flow cytometry pilot study

artículo científico publicado en 2012

Phenotypic Screening of Chemical Libraries Enriched by Molecular Docking to Multiple Targets Selected from Glioblastoma Genomic Data

scientific article published on 03 April 2020

Phenotypic correction of primary Fanconi anemia T cells with retroviral vectors as a diagnostic tool.

artículo científico publicado en 2002

Phosphorylation of NMDA 2B at S1303 in human glioma peritumoral tissue: implications for glioma epileptogenesis

artículo científico publicado en 2014

Potentiation of Carboplatin-Mediated DNA Damage by the Mdm2 Modulator Nutlin-3a in a Humanized Orthotopic Breast-to-Lung Metastatic Model.

artículo científico publicado en 2015

Preclinical activity of a novel multiple tyrosine kinase and aurora kinase inhibitor, ENMD-2076, against multiple myeloma

artículo científico publicado en 2010

Presence of stromal cells in a bioengineered tumor microenvironment alters glioblastoma migration and response to STAT3 inhibition.

artículo científico publicado en 2018

Real-Time PCR: an Effective Tool for Measuring Transduction Efficiency in Human Hematopoietic Progenitor Cells

artículo científico publicado en 2004

Retroviral Vector Production by Transient Transfection

article

Retroviral Vectors for Gene Transfer

article

Selenomethionine or methylseleninic acid inhibits mutagenesis of a reporter gene in mouse bone marrow.

artículo científico publicado en 2010

Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric Inhibition of the TEAD⋅Yap Protein-Protein Interaction

artículo científico publicado en 2018

Small-molecule inhibition of the uPAR·uPA interaction: Synthesis, biochemical, cellular, in vivo pharmacokinetics and efficacy studies in breast cancer metastasis ⬇️

artículo científico publicado el 9 de enero de 2013

Soypeptide lunasin in cytokine immunotherapy for lymphoma.

scientific article published on 22 December 2013

Sulforaphane suppresses the growth of glioblastoma cells, glioblastoma stem cell-like spheroids, and tumor xenografts through multiple cell signaling pathways

artículo científico publicado en 2017

Systems Biology Approach Identifies Prognostic Signatures of Poor Overall Survival and Guides the Prioritization of Novel BET-CHK1 Combination Therapy for Osteosarcoma

artículo científico publicado en 2020

TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer

artículo científico publicado en 2009

TRTH-14. TARGETING CHK1 AND AKT CROSSTALK IN MUTANT P53 PEDIATRIC GLIOBLASTOMA.

artículo científico publicado en 2017

Targeting the Anti-Apoptotic Protein c-FLIP for Cancer Therapy ⬇️

artículo científico publicado el 1 de junio de 2011

Temozolomide-Mediated DNA Methylation in Human Myeloid Precursor Cells: Differential Involvement of Intrinsic and Extrinsic Apoptotic Pathways ⬇️

artículo científico publicado el 27 de marzo de 2013

The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches

artículo científico publicado en 2016

The Role of MDM2 in Promoting Genome Stability versus Instability.

artículo científico publicado en 2017

The Xpc gene markedly affects cell survival in mouse bone marrow

artículo científico publicado en 2009

Transduction of Cell Lines by Retroviral Vectors

artículo científico publicado en 2008

Transduction of Primary Hematopoietic Cells by Retroviral Vectors

artículo científico publicado en 2008

Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation

artículo científico publicado en 2008

UVB radiation-mediated inhibition of contact hypersensitivity reactions is dependent on the platelet-activating factor system

artículo científico publicado en 2008

Virtual screening targeting the urokinase receptor, biochemical and cell-based studies, synthesis, pharmacokinetic characterization, and effect on breast tumor metastasis

artículo científico publicado en 2011

c-FLIP gene silencing eliminates tumor cells in breast cancer xenografts without affecting stromal cells

artículo científico publicado en 2009

Lista de obras de Karen E. Pollok

3552 Advancing Glioblastoma (GBM) drug regimen development to support combination therapy through integrated PKPD modeling and simulation-based predictions

A heterobivalent ligand inhibits mast cell degranulation via selective inhibition of allergen-IgE interactions in vivo

A novel competitive repopulation strategy to quantitate engraftment of ex vivo manipulated murine marrow cells in submyeloablated hosts

A theoretically optimized method for cord blood stem cell cryopreservation

ATPS-75TARGETING THE Mdm2-Akt SIGNALING NETWORK IN COMBINATION WITH TEMOZOLOMIDE IMPROVES EFFICACY IN ECTOPIC AND ORTHOTOPIC PATIENT-DERIVED GLIOBLASTOMA XENOGRAFT MODELS.

Acridine Orange as a Novel Photosensitizer for Photodynamic Therapy in Glioblastoma

Activation of death-associated protein kinase in human peritumoral tissue: A potential therapeutic target

Application of polychromatic flow cytometry to identify novel subsets of circulating cells with angiogenic potential

Chemotherapeutic selectivity conferred by selenium: a role for p53-dependent DNA repair

Combination therapy in a xenograft model of glioblastoma: enhancement of the antitumor activity of temozolomide by an MDM2 antagonist

Comparison of three retroviral vector systems for transduction of nonobese diabetic/severe combined immunodeficiency mice repopulating human CD34+ cord blood cells.

Design, synthesis, and evaluation of curcumin-derived arylheptanoids for glioblastoma and neuroblastoma cytotoxicity

Differential Secondary Reconstitution of In Vivo-Selected Human SCID-Repopulating Cells in NOD/SCID versus NOD/SCID/γ chain Mice

Dual PI3K and Wnt pathway inhibition is a synergistic combination against triple negative breast cancer

ET-25THERAPEUTIC MODULATION OF MDM2 IN NEUROBLASTOMA

Emerging targets for glioblastoma stem cell therapy

Enhanced anticancer properties of lomustine in conjunction with docosahexaenoic acid in glioblastoma cell lines.

Enhanced homing and engraftment of fresh but not ex vivo cultured murine marrow cells in submyeloablated hosts following CD26 inhibition by Diprotin A

Evaluation of plasmid DNA removal from lentiviral vectors by benzonase treatment

Exploring a structural protein-drug interactome for new therapeutics in lung cancer

G2 cell cycle arrest and cyclophilin A in lentiviral gene transfer

Gene Co-Expression Networks Restructured Gene Fusion in Rhabdomyosarcoma Cancers

Generation of Stable Vector-Producing Cells for Retroviral Vectors

Glioblastoma stem cells (GSCs) epigenetic plasticity and interconversion between differentiated non-GSCs and GSCs.

Hematopoietic expression of O(6)-methylguanine DNA methyltransferase-P140K allows intensive treatment of human glioma xenografts with combination O(6)-benzylguanine and 1,3-bis-(2-chloroethyl)-1-nitrosourea

Human proangiogenic circulating hematopoietic stem and progenitor cells promote tumor growth in an orthotopic melanoma xenograft model

Humanized Bone Marrow Mouse Model as a Preclinical Tool to Assess Therapy-Mediated Hematotoxicity ⬇️

Hypoxia-Inducible Factor-1α Regulates CD55 in Airway Epithelium

Identification and Characterization of New Chemical Entities Targeting Apurinic/Apyrimidinic Endonuclease 1 for the Prevention of Chemotherapy-Induced Peripheral Neuropathy

Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood

Identification of parameters required for efficient lentiviral vector transduction and engraftment of human cord blood CD34(+) NOD/SCID-repopulating cells

Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growth

In Vivo Measurements of Tumor Metabolism and Growth after Administration of Enzastaurin Using Small Animal FDG Positron Emission Tomography

In vivo effects of myeloablative alkylator therapy on survival and differentiation of MGMTP140K-transduced human G-CSF-mobilized peripheral blood cells

In vivo protection of hematopoietic cells from alkylator-mediated DNA damage

In vivo selection of hematopoietic stem cells transduced at a low multiplicity-of-infection with a foamy viral MGMT(P140K) vector

In vivo selection of human hematopoietic cells in a xenograft model using combined pharmacologic and genetic manipulations

Inhibition of CD26 in human cord blood CD34+ cells enhances their engraftment of nonobese diabetic/severe combined immunodeficiency mice

Integration of genomic copy number variations and chemotherapy-response biomarkers in pediatric sarcoma

Involvement of platelet-activating factor in ultraviolet B-induced hyperalgesia

Lentiviral vectors pseudotyped with glycoproteins from Ross River and vesicular stomatitis viruses: variable transduction related to cell type and culture conditions

Letrozole targets the Human ether-a-go-go-related gene (HERG) potassium current in glioblastoma

Longitudinal Bioluminescence Imaging of Primary Versus Abdominal Metastatic Tumor Growth in Orthotopic Pancreatic Tumor Models in NSG Mice

Melanoma LAMP-2C Modulates Tumor Growth and Autophagy

Mesenchymal stem/progenitor cells promote the reconstitution of exogenous hematopoietic stem cells in Fancg-/- mice in vivo

Mitochondrial targeting of human O6-methylguanine DNA methyltransferase protects against cell killing by chemotherapeutic alkylating agents

Multimodality imaging methods for assessing retinoblastoma orthotopic xenograft growth and development

Observations on spontaneous tumor formation in mice overexpressing mitotic kinesin Kif14

PET imaging and optical imaging with D-luciferin [11C]methyl ester and D-luciferin [11C]methyl ether of luciferase gene expression in tumor xenografts of living mice

PTEN and p53 are required for hypoxia induced expression of maspin in glioblastoma cells

Peripheral blood biomarkers of solid tumor angiogenesis in dogs: a polychromatic flow cytometry pilot study

Phenotypic Screening of Chemical Libraries Enriched by Molecular Docking to Multiple Targets Selected from Glioblastoma Genomic Data

Phenotypic correction of primary Fanconi anemia T cells with retroviral vectors as a diagnostic tool.

Phosphorylation of NMDA 2B at S1303 in human glioma peritumoral tissue: implications for glioma epileptogenesis

Potentiation of Carboplatin-Mediated DNA Damage by the Mdm2 Modulator Nutlin-3a in a Humanized Orthotopic Breast-to-Lung Metastatic Model.

Preclinical activity of a novel multiple tyrosine kinase and aurora kinase inhibitor, ENMD-2076, against multiple myeloma

Presence of stromal cells in a bioengineered tumor microenvironment alters glioblastoma migration and response to STAT3 inhibition.

Real-Time PCR: an Effective Tool for Measuring Transduction Efficiency in Human Hematopoietic Progenitor Cells

Retroviral Vector Production by Transient Transfection

Retroviral Vectors for Gene Transfer

Selenomethionine or methylseleninic acid inhibits mutagenesis of a reporter gene in mouse bone marrow.

Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric Inhibition of the TEAD⋅Yap Protein-Protein Interaction

Small-molecule inhibition of the uPAR·uPA interaction: Synthesis, biochemical, cellular, in vivo pharmacokinetics and efficacy studies in breast cancer metastasis ⬇️

Soypeptide lunasin in cytokine immunotherapy for lymphoma.

Sulforaphane suppresses the growth of glioblastoma cells, glioblastoma stem cell-like spheroids, and tumor xenografts through multiple cell signaling pathways

Systems Biology Approach Identifies Prognostic Signatures of Poor Overall Survival and Guides the Prioritization of Novel BET-CHK1 Combination Therapy for Osteosarcoma

TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer

TRTH-14. TARGETING CHK1 AND AKT CROSSTALK IN MUTANT P53 PEDIATRIC GLIOBLASTOMA.

Targeting the Anti-Apoptotic Protein c-FLIP for Cancer Therapy ⬇️

Temozolomide-Mediated DNA Methylation in Human Myeloid Precursor Cells: Differential Involvement of Intrinsic and Extrinsic Apoptotic Pathways ⬇️

The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches

The Role of MDM2 in Promoting Genome Stability versus Instability.

The Xpc gene markedly affects cell survival in mouse bone marrow

Transduction of Cell Lines by Retroviral Vectors

Transduction of Primary Hematopoietic Cells by Retroviral Vectors

Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation

UVB radiation-mediated inhibition of contact hypersensitivity reactions is dependent on the platelet-activating factor system

Virtual screening targeting the urokinase receptor, biochemical and cell-based studies, synthesis, pharmacokinetic characterization, and effect on breast tumor metastasis

c-FLIP gene silencing eliminates tumor cells in breast cancer xenografts without affecting stromal cells