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Lista de obras de Guido Silvestri

A Blueprint for HIV Vaccine Discovery

artículo científico publicado en 2012

A five-year longitudinal analysis of sooty mangabeys naturally infected with simian immunodeficiency virus reveals a slow but progressive decline in CD4+ T-cell count whose magnitude is not predicted by viral load or immune activation

artículo científico publicado en 2010

A novel CCR5 mutation common in sooty mangabeys reveals SIVsmm infection of CCR5-null natural hosts and efficient alternative coreceptor use in vivo

artículo científico publicado en 2010

Activated CD4+CCR5+ T cells in the rectum predict increased SIV acquisition in SIVGag/Tat-vaccinated rhesus macaques.

artículo científico publicado en 2014

Analysis of the In Vivo Turnover of CD4+ T-Cell Subsets in Chronically SIV-Infected Sooty Mangabeys

artículo científico publicado en 2016

Animal models for viral infection and cell exhaustion

artículo científico publicado en 2014

Animal models to achieve an HIV cure

artículo científico publicado en 2016

Antiretroviral Therapy in Simian Immunodeficiency Virus-Infected Sooty Mangabeys: Implications for AIDS Pathogenesis

artículo científico publicado en 2016

Author Correction: Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells

artículo científico publicado en 2020

Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys

artículo científico publicado en 2008

B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen

artículo científico publicado en 2011

Bone marrow-based homeostatic proliferation of mature T cells in nonhuman primates: implications for AIDS pathogenesis

artículo científico publicado en 2008

CCL3L Copy number variation and the co-evolution of primate and viral genomes

artículo científico publicado en 2009

CCR5 blockade is well tolerated and induces changes in the tissue distribution of CCR5+ and CD25+ T cells in healthy, SIV-uninfected rhesus macaques

artículo científico publicado en 2011

CD127 and CD25 expression defines CD4+ T cell subsets that are differentially depleted during HIV infection

artículo científico publicado en 2008

CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells

artículo científico publicado en 2014

CD4+ T-cell depletion in HIV infection: killed by friendly fire?

artículo científico publicado en 2005

CD4-like immunological function by CD4- T cells in multiple natural hosts of simian immunodeficiency virus

artículo científico publicado en 2011

CD8(+) Lymphocytes Are Required for Maintaining Viral Suppression in SIV-Infected Macaques Treated with Short-Term Antiretroviral Therapy.

artículo científico publicado en 2016

CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells

artículo científico publicado en 2010

Cell cycle dysregulation during HIV infection: perspectives of a target based therapy

artículo científico publicado en 2002

Cloning and analysis of sooty mangabey alternative coreceptors that support simian immunodeficiency virus SIVsmm entry independently of CCR5.

artículo científico publicado en 2011

Coexpression Network Analysis of Benign and Malignant Phenotypes of SIV-Infected Sooty Mangabey and Rhesus Macaque

artículo científico publicado en 2016

Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque

artículo científico publicado en 2011

Correction for Mavigner et al., "Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques"

Correction: Decreased T Follicular Regulatory Cell/T Follicular Helper Cell (T(FH)) in Simian Immunodeficiency Virus-Infected Rhesus Macaques May Contribute to Accumulation of T(FH) in Chronic Infection

artículo científico publicado en 2015

Correlates of relative resistance against low-dose rectal simian immunodeficiency virus challenges in peripheral blood mononuclear cells of vaccinated rhesus macaques

artículo científico publicado en 2012

Critical role of CD4 T cells in maintaining lymphoid tissue structure for immune cell homeostasis and reconstitution.

artículo científico publicado en 2012

Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections

artículo científico publicado en 2011

Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections

artículo científico publicado en 2010

Decreased T Follicular Regulatory Cell/T Follicular Helper Cell (TFH) in Simian Immunodeficiency Virus-Infected Rhesus Macaques May Contribute to Accumulation of TFH in Chronic Infection

artículo científico publicado en 2015

Depletion of CD4⁺ T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques

artículo científico publicado en 2011

Differential Impact of In Vivo CD8+ T Lymphocyte Depletion in Controller versus Progressor Simian Immunodeficiency Virus-Infected Macaques.

artículo científico publicado en 2015

Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections

artículo científico publicado en 2008

Differential infection patterns of CD4+ T cells and lymphoid tissue viral burden distinguish progressive and nonprogressive lentiviral infections

artículo científico publicado en 2012

Disruption of intestinal CD4+ T cell homeostasis is a key marker of systemic CD4+ T cell activation in HIV-infected individuals

artículo científico publicado en 2010

Divergent CD4+ T memory stem cell dynamics in pathogenic and nonpathogenic simian immunodeficiency virus infections

artículo científico publicado en 2014

Divergent host responses during primary simian immunodeficiency virus SIVsm infection of natural sooty mangabey and nonnatural rhesus macaque hosts

artículo científico publicado en 2005

Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques

artículo científico publicado en 2010

Dualtropic CXCR6/CCR5 Simian Immunodeficiency Virus (SIV) Infection of Sooty Mangabey Primary Lymphocytes: Distinct Coreceptor Use in Natural versus Pathogenic Hosts of SIV

artículo científico publicado en 2015

Dynamics of simian immunodeficiency virus SIVmac239 infection in pigtail macaques

artículo científico publicado en 2011

Early resolution of acute immune activation and induction of PD-1 in SIV-infected sooty mangabeys distinguishes nonpathogenic from pathogenic infection in rhesus macaques

artículo científico publicado en 2008

Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches

artículo científico publicado en 2017

From structure to sequence: Antibody discovery using cryoEM

scientific article published on 19 January 2022

Generalized immune activation and innate immune responses in simian immunodeficiency virus infection

artículo científico publicado el 1 de septiembre de 2011

Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys

artículo científico publicado en 2009

HIV and Tfh Cells: Circulating New Ideas to Identify and Protect

artículo científico publicado en 2016

HIV therapeutic vaccines: moving towards a functional cure

artículo científico publicado en 2015

Host–pathogen interaction in HIV infection

artículo científico publicado el 24 de julio de 2013

Identification and characterization of HIV-specific resident memory CD8 + T cells in human lymphoid tissue

article

Immune activation alters cellular and humoral responses to yellow fever 17D vaccine

artículo científico publicado en 2014

Immunovirological Analyses of Chronically Simian Immunodeficiency Virus SIVmnd-1- and SIVmnd-2-Infected Mandrills (Mandrillus sphinx).

artículo científico publicado en 2012

Immunovirological analyses of chronically simian immunodeficiency virus SIVmnd-1- and SIVmnd-2-infected mandrills (Mandrillus sphinx).

artículo científico publicado en 2011

Impaired in-vitro growth of megakaryocytic colonies derived from CD34 cells of HIV-1-infected patients with active viral replication

artículo científico publicado en 2006

In Vivo Models of Human Immunodeficiency Virus Persistence and Cure Strategies

artículo científico publicado en 2017

Increased mortality and AIDS-like immunopathology in wild chimpanzees infected with SIVcpz

artículo científico publicado en 2009

Increased stability and limited proliferation of CD4+ central memory T cells differentiate nonprogressive simian immunodeficiency virus (SIV) infection of sooty mangabeys from progressive SIV infection of rhesus macaques.

artículo científico publicado en 2014

Inefficient Nef-mediated downmodulation of CD3 and MHC-I correlates with loss of CD4+T cells in natural SIV infection

artículo científico publicado en 2008

Initiation of Antiretroviral Therapy Restores CD4+ T Memory Stem Cell Homeostasis in Simian Immunodeficiency Virus-Infected Macaques

artículo científico publicado en 2016

Intact type I Interferon production and IRF7 function in sooty mangabeys

artículo científico publicado en 2013

Interleukin-21 combined with ART reduces inflammation and viral reservoir in SIV-infected macaques

artículo científico publicado en 2015

Into the wild: simian immunodeficiency virus (SIV) infection in natural hosts

artículo científico publicado en 2008

Lack of clinical AIDS in SIV-infected sooty mangabeys with significant CD4+ T cell loss is associated with double-negative T cells.

artículo científico publicado en 2011

Lessons learned from the natural hosts of HIV-related viruses

artículo científico publicado en 2009

Limited HIV infection of central memory and stem cell memory CD4+ T cells is associated with lack of progression in viremic individuals

artículo científico publicado en 2014

Lineage-specific T-cell reconstitution following in vivo CD4+ and CD8+ lymphocyte depletion in nonhuman primates

artículo científico publicado en 2010

Link between primate lentiviral coreceptor usage and Nef function

artículo científico publicado en 2013

Liver macrophage-associated inflammation correlates with SIV burden and is substantially reduced following cART.

artículo científico publicado en 2018

Low levels of SIV infection in sooty mangabey central memory CD⁴⁺ T cells are associated with limited CCR5 expression

artículo científico publicado en 2011

Maintenance of intestinal Th17 cells and reduced microbial translocation in SIV-infected rhesus macaques treated with interleukin (IL)-21

artículo científico publicado en 2013

Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

scientific article published on 31 August 2020

Mechanisms of CD8+ T cell-mediated suppression of HIV/SIV replication.

artículo científico publicado en 2018

Microbial translocation is a cause of systemic immune activation in chronic HIV infection

artículo científico publicado en 2006

Mode of transmission affects the sensitivity of human immunodeficiency virus type 1 to restriction by rhesus TRIM5alpha

artículo científico publicado en 2008

Mother-to-Infant Transmission of Simian Immunodeficiency Virus Is Rare in Sooty Mangabeys and Is Associated with Low Viremia

artículo científico publicado el 30 de marzo de 2011

Multifunctional Double-negative T Cells in Sooty Mangabeys Mediate T-helper Functions Irrespective of SIV Infection

artículo científico publicado el 27 de junio de 2013

Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1

artículo científico publicado en 2006

Neutralizing human monoclonal antibodies prevent Zika virus infection in macaques.

artículo científico publicado en 2017

Nonpathogenic simian immunodeficiency virus infection of sooty mangabeys is not associated with high levels of autologous neutralizing antibodies

artículo científico publicado en 2010

Nonprogressive and progressive primate immunodeficiency lentivirus infections

artículo científico publicado en 2010

PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques

artículo científico publicado en 2012

Paucity of IL-21–producing CD4+ T cells is associated with Th17 cell depletion in SIV infection of rhesus macaques

artículo científico publicado el 18 de septiembre de 2012

Persistence of virus reservoirs in ART-treated SHIV-infected rhesus macaques after autologous hematopoietic stem cell transplant

artículo científico publicado en 2014

Plasmacytoid Dendritic Cell Infection and Sensing Capacity during Pathogenic and Nonpathogenic Simian Immunodeficiency Virus Infection

artículo científico publicado en 2015

Plasmacytoid dendritic cells are recruited to the colorectum and contribute to immune activation during pathogenic SIV infection in rhesus macaques

artículo científico publicado en 2011

Postnatal Zika virus infection is associated with persistent abnormalities in brain structure, function, and behavior in infant macaques

artículo científico publicado en 2018

Primate genomes for biomedicine

artículo científico publicado en 2011

Proceedings of the Frontiers of Retrovirology Conference 2016.

artículo científico publicado en 2016

Prospects for an AIDS vaccine: three big questions, no easy answers.

artículo científico publicado en 2004

Protection afforded by an HIV vaccine candidate in macaques depends on the dose of SIVmac251 at challenge exposure

artículo científico publicado en 2013

Quantifying integrated SIV-DNA by repetitive-sampling Alu-gag PCR.

artículo científico publicado en 2016

Reconstitution of intestinal CD4 and Th17 T cells in antiretroviral therapy suppressed HIV-infected subjects: implication for residual immune activation from the results of a clinical trial

artículo científico publicado en 2014

Reduced Simian Immunodeficiency Virus Replication in Macrophages of Sooty Mangabeys Is Associated with Increased Expression of Host Restriction Factors

artículo científico publicado en 2015

Reduced inflammation and lymphoid tissue immunopathology in rhesus macaques receiving anti-tumor necrosis factor treatment during primary simian immunodeficiency virus infection

artículo científico publicado en 2012

Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4+ T cells, and disease progression

artículo científico publicado en 2015

Reply to "Control of Simian Immunodeficiency Virus SIVmnd-1 RNA Plasma Viremia after Coinfection or Superinfection with SIVmnd-1 in SIVmnd-2-Infected Mandrills and Vice Versa".

artículo científico publicado en 2012

Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells

scientific article published on 22 January 2020

Severe depletion of mucosal CD4+ T cells in AIDS-free simian immunodeficiency virus-infected sooty mangabeys

artículo científico publicado en 2007

Short-lived infected cells support virus replication in sooty mangabeys naturally infected with simian immunodeficiency virus: implications for AIDS pathogenesis

artículo científico publicado en 2008

Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques

scholarly article by Maud Mavigner et al published 15 September 2018 in Journal of Virology

Simian immunodeficiency virus-induced alterations in monocyte production of tumor necrosis factor alpha contribute to reduced immune activation in sooty mangabeys

artículo científico publicado en 2012

Similar impact of CD8+ T cell responses on early virus dynamics during SIV infections of rhesus macaques and sooty mangabeys

artículo científico publicado en 2010

Sooty mangabey genome sequence provides insight into AIDS resistance in a natural SIV host

artículo científico publicado en 2018

Strong TH1-biased CD4 T cell responses are associated with diminished SIV vaccine efficacy

artículo científico publicado en 2019

Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo

scientific article published on 22 January 2020

Systems biology of natural simian immunodeficiency virus infections

artículo científico publicado en 2012

T memory stem cells and HIV: a long-term relationship

artículo científico publicado en 2015

TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition

artículo científico publicado en 2014

Taming HIV-related inflammation with physical activity: a matter of timing

artículo científico publicado en 2014

Target cell availability, rather than breast milk factors, dictates mother-to-infant transmission of SIV in sooty mangabeys and rhesus macaques

artículo científico publicado en 2014

The AIDS resistance of naturally SIV-infected sooty mangabeys is independent of cellular immunity to the virus

artículo científico publicado en 2006

The Effect of Chloroquine on Immune Activation and Interferon Signatures Associated with HIV-1.

artículo científico publicado en 2016

The evolution of infectious agents in relation to sex in animals and humans: brief discussions of some individual organisms

artículo científico publicado en 2011

The myeloid cytokine network in AIDS pathogenesis

artículo científico publicado en 2012

Timely triggering of homeostatic mechanisms involved in the regulation of T-cell levels in SIVsm-infected sooty mangabeys

artículo científico publicado en 2005

Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts

artículo científico publicado en 2009

Towards an HIV cure: a global scientific strategy

artículo científico publicado en 2012

Transcriptional Profiling of Experimental CD8+Lymphocyte Depletion in Rhesus Macaques Infected with Simian Immunodeficiency Virus SIVmac239

artículo científico publicado el 24 de octubre de 2012

Treatment of SIV-infected sooty mangabeys with a type-I IFN agonist results in decreased virus replication without inducing hyperimmune activation

artículo científico publicado en 2012

Turnover of lymphocytes and conceptual paradigms in HIV infection

artículo científico publicado en 2003

Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression

artículo científico publicado en 2014

Understanding the benign nature of SIV infection in natural hosts

artículo científico publicado en 2007

Vaccine-induced T cells provide partial protection against high-dose rectal SIVmac239 challenge of rhesus macaques

artículo científico publicado en 2010

Vaccinia virus tropism for primary hematolymphoid cells is determined by restricted expression of a unique virus receptor

artículo científico publicado en 2005

Viral CTL Escape Mutants Are Generated in Lymph Nodes and Subsequently Become Fixed in Plasma and Rectal Mucosa during Acute SIV Infection of Macaques

artículo científico publicado el 19 de mayo de 2011

What pediatric nonprogressors and natural SIV hosts teach us about HIV.

artículo científico publicado en 2016

Why don't CD8+ T cells reduce the lifespan of SIV-infected cells in vivo?

artículo científico publicado en 2011