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Lista de obras de Joseph Sodroski

540. Investigating the Mechanism of a Unique Human Immunodeficiency Virus-1 (HIV-1) Entry Inhibitor, MF275

article

A B-box 2 surface patch important for TRIM5alpha self-association, capsid binding avidity, and retrovirus restriction

artículo científico publicado en 2009

A CD4-mimetic compound enhances vaccine efficacy against stringent immunodeficiency virus challenge.

artículo científico publicado en 2018

A Small-Molecule CD4-mimetic Compound Protects BLT Humanized Mice from Human Immunodeficiency Virus Infection.

artículo científico publicado en 2018

A V3 loop-dependent gp120 element disrupted by CD4 binding stabilizes the human immunodeficiency virus envelope glycoprotein trimer.

artículo científico publicado en 2010

A human TRIM5alpha B30.2/SPRY domain mutant gains the ability to restrict and prematurely uncoat B-tropic murine leukemia virus

artículo científico publicado en 2008

A new classification for HIV-1

artículo científico publicado en 1998

A rapid method for quantitating the frequency of peripheral blood cells containing HIV-1 DNA

artículo científico publicado el 1 de enero de 1991

A rare null allele potentially encoding a dominant-negative TRIM5alpha protein in Baka pygmies

artículo científico publicado en 2009

A second post-transcriptional trans-activator gene required for HTLV-III replication

artículo científico publicado en 1986

A soluble CD4 protein selectively inhibits HIV replication and syncytium formation

artículo científico publicado en 1988

A transcriptional activator protein encoded by the x-lor region of the human T-cell leukemia virus

artículo científico publicado en 1985

A twin-cysteine motif in the V2 region of gp120 is associated with SIV envelope trimer stabilization

artículo científico publicado en 2013

Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1

artículo científico publicado en 2003

Activation and Inactivation of Primary Human Immunodeficiency Virus Envelope Glycoprotein Trimers by CD4-Mimetic Compounds

artículo científico publicado en 2016

Adaptation of HIV-1 to cells expressing rhesus monkey TRIM5α

artículo científico publicado en 2010

Adaptation of HIV-1 to cells with low expression of the CCR5 coreceptor

artículo científico publicado en 2017

Adaptation of human immunodeficiency virus type 1 to cells expressing a binding-deficient CD4 mutant (lysine 46 to aspartic acid)

artículo científico publicado en 1995

Adaptation of the human immunodeficiency virus type 1 envelope glycoproteins to new world monkey receptors

artículo científico publicado en 2007

Adoption of an "open" envelope conformation facilitating CD4 binding and structural remodeling precedes coreceptor switch in R5 SHIV-infected macaques

artículo científico publicado en 2011

Amino Acid Changes in the HIV-1 gp41 Membrane Proximal Region Control Virus Neutralization Sensitivity

scientific article published on 31 August 2016

Amino acid residues of the human immunodeficiency virus type I gp120 critical for the binding of rat and human neutralizing antibodies that block the gp120-sCD4 interaction

artículo científico publicado en 1992

Amino acid sequence requirements for the incorporation of the Vpx protein of simian immunodeficiency virus into virion particles.

artículo científico publicado en 1995

An alternative conformation of the gp41 heptad repeat 1 region coiled coil exists in the human immunodeficiency virus (HIV-1) envelope glycoprotein precursor

artículo científico publicado en 2005

An entry-competent intermediate state of the HIV-1 envelope glycoproteins

artículo científico publicado en 2017

An unrelated monoclonal antibody neutralizes human immunodeficiency virus type 1 by binding to an artificial epitope engineered in a functionally neutral region of the viral envelope glycoproteins

artículo científico publicado en 2005

Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors

artículo científico publicado en 2011

Analysis of the Interaction of Antibodies with a Conserved, Enzymatically Deglycosylated Core of the HIV Type 1 Envelope Glycoprotein 120 ⬇️

artículo científico publicado el 10 de febrero de 1998

Analysis of the neutralizing antibody response elicited in rabbits by repeated inoculation with trimeric HIV-1 envelope glycoproteins.

artículo científico publicado en 2005

Antibodies Elicited by Multiple Envelope Glycoprotein Immunogens in Primates Neutralize Primary Human Immunodeficiency Viruses (HIV-1) Sensitized by CD4-Mimetic Compounds

artículo científico publicado en 2016

Antibodies to CD4 in individuals infected with human immunodeficiency virus type 1.

artículo científico publicado en 1989

Antibody 17b binding at the coreceptor site weakens the kinetics of the interaction of envelope glycoprotein gp120 with CD4.

artículo científico publicado en 2001

Antibody binding in proximity to the receptor/glycoprotein complex leads to a basal level of virus neutralization

artículo científico publicado en 2007

Antibody binding is a dominant determinant of the efficiency of human immunodeficiency virus type 1 neutralization

artículo científico publicado en 2006

Antigenic characterization of the human immunodeficiency virus (HIV-1) envelope glycoprotein precursor incorporated into nanodiscs

artículo científico publicado en 2017

Antigenic variation in gp120s from molecular clones of HIV-1 LAI

artículo científico publicado en 1993

Antigens Encoded by the 3′-Terminal Region of Human T-Cell Leukemia Virus: Evidence for a Functional Gene ⬇️

artículo científico publicado el 5 de octubre de 1984

Apelin, the natural ligand of the orphan seven-transmembrane receptor APJ, inhibits human immunodeficiency virus type 1 entry.

artículo científico publicado en 2000

Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET

scientific article published on 10 April 2019

Association of structural changes in the V2 and V3 loops of the gp120 envelope glycoprotein with acquisition of neutralization resistance in a simian-human immunodeficiency virus passaged in vivo

artículo científico publicado en 2000

Asymmetric Structures and Conformational Plasticity of the Uncleaved Full-Length Human Immunodeficiency Virus Envelope Glycoprotein Trimer

artículo científico publicado en 2021

BST-2 Expression Modulates Small CD4-Mimetic Sensitization of HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity

artículo científico publicado en 2017

Beta-turn Phe in HIV-1 Env binding site of CD4 and CD4 mimetic miniprotein enhances Env binding affinity but is not required for activation of co-receptor/17b site

artículo científico publicado en 2002

Binding and susceptibility to postentry restriction factors in monkey cells are specified by distinct regions of the human immunodeficiency virus type 1 capsid

artículo científico publicado en 2004

Biochemical and biophysical characterization of a chimeric TRIM21-TRIM5alpha protein

artículo científico publicado en 2008

Blockade of HIV-1 infection of New World monkey cells occurs primarily at the stage of virus entry

artículo científico publicado en 2002

CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia

artículo científico publicado en 1997

CCR5 has an expanded ligand-binding repertoire and is the primary receptor used by MCP-2 on activated T cells

artículo científico publicado en 1998

CD4 binding site antibodies inhibit human immunodeficiency virus gp120 envelope glycoprotein interaction with CCR5

artículo científico publicado en 2003

CD4-Independent Binding of SIV gp120 to Rhesus CCR5 ⬇️

artículo científico publicado el 21 de noviembre de 1997

CD4-Induced Conformational Changes in the Human Immunodeficiency Virus Type 1 gp120 Glycoprotein: Consequences for Virus Entry and Neutralization ⬇️

artículo científico publicado el 1 de junio de 1998

CD4-induced T-20 binding to human immunodeficiency virus type 1 gp120 blocks interaction with the CXCR4 coreceptor

artículo científico publicado en 2004

CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5.

artículo científico publicado en 1996

CD4-mimetic small molecules sensitize human immunodeficiency virus to vaccine-elicited antibodies

artículo científico publicado en 2014

Capture and reconstitution of G protein-coupled receptors on a biosensor surface

scientific article published on 01 May 2003

Cell lines that express stably env gene products from three strains of HIV-1.

artículo científico publicado en 1988

Characterization of CD4-induced epitopes on the HIV type 1 gp120 envelope glycoprotein recognized by neutralizing human monoclonal antibodies

artículo científico publicado en 2002

Characterization of TRIM5alpha trimerization and its contribution to human immunodeficiency virus capsid binding

artículo científico publicado en 2006

Characterization of a core fragment of the rhesus monkey TRIM5α protein ⬇️

artículo científico publicado el 4 de enero de 2011

Characterization of a dual-tropic human immunodeficiency virus (HIV-1) strain derived from the prototypical X4 isolate HXBc2.

artículo científico publicado en 2013

Characterization of antibody responses to purified HIV-1 gp120 glycoproteins fused with the molecular adjuvant C3d

artículo científico publicado en 2005

Characterization of human immunodeficiency virus type 1 monomeric and trimeric gp120 glycoproteins stabilized in the CD4-bound state: antigenicity, biophysics, and immunogenicity ⬇️

artículo científico publicado en 2007

Characterization of simian-human immunodeficiency virus envelope glycoprotein epitopes recognized by neutralizing antibodies from infected monkeys

artículo científico publicado en 1998

Characterization of stable, soluble trimers containing complete ectodomains of human immunodeficiency virus type 1 envelope glycoproteins

artículo científico publicado en 2000

Characterization of the cDNA of a broadly reactive neutralizing human anti-gp120 monoclonal antibody ⬇️

artículo científico publicado el 1 de octubre de 1992

Characterization of the multiple conformational States of free monomeric and trimeric human immunodeficiency virus envelope glycoproteins after fixation by cross-linker

artículo científico publicado en 2006

Characterization of the outer domain of the gp120 glycoprotein from human immunodeficiency virus type 1

artículo científico publicado en 2004

Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins

artículo científico publicado en 2016

Comparative Analysis of the Glycosylation Profiles of Membrane-Anchored HIV-1 Envelope Glycoprotein Trimers and Soluble gp140

artículo científico publicado en 2015

Comparative requirements for the restriction of retrovirus infection by TRIM5alpha and TRIMCyp

artículo científico publicado en 2007

Comparison of Uncleaved and Mature Human Immunodeficiency Virus (HIV-1) Membrane Envelope Glycoprotein Trimers.

artículo científico publicado en 2018

Complex determinants within the Moloney murine leukemia virus capsid modulate susceptibility of the virus to Fv1 and Ref1-mediated restriction

artículo científico publicado en 2007

Conformational Differences Between Functional Human Immunodeficiency Virus (HIV-1) Envelope Glycoprotein Trimers and Stabilized Soluble Trimers

article

Conformational changes in env oligomer induced by an antibody dependent on the V3 loop base

scientific article published on 01 March 2003

Conformational changes of gp120 in epitopes near the CCR5 binding site are induced by CD4 and a CD4 miniprotein mimetic

artículo científico publicado en 1999

Conformational characterization of aberrant disulfide-linked HIV-1 gp120 dimers secreted from overexpressing cells.

artículo científico publicado en 2010

Contribution of PDZD8 to stabilization of the human immunodeficiency virus type 1 capsid

artículo científico publicado en 2014

Contribution of charged amino acids in the CDR2 region of CD4 to HIV-1 gp120 binding

artículo científico publicado el 1 de enero de 1992

Contribution of disulfide bonds in the carboxyl terminus of the human immunodeficiency virus type I gp120 glycoprotein to CD4 binding

artículo científico publicado en 1992

Contribution of intrinsic reactivity of the HIV-1 envelope glycoproteins to CD4-independent infection and global inhibitor sensitivity.

artículo científico publicado en 2011

Contribution of the gp120 V3 loop to envelope glycoprotein trimer stability in primate immunodeficiency viruses

artículo científico publicado en 2018

Control of gene expression and the replication and pathogenesis of retroviruses

artículo científico publicado en 1986

Cooperativity of neutralizing antibodies directed against the V3 and CD4 binding regions of the human immunodeficiency virus gp120 envelope glycoprotein

artículo científico publicado en 1992

Corrigendum to: Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes [Virology 475 (2015) 37–45]

article

Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529.

artículo científico publicado en 2017

Cyclophilin A: an auxiliary but not necessary cofactor for TRIM5alpha restriction of HIV-1.

artículo científico publicado en 2006

Cytolysis by CCR5-using human immunodeficiency virus type 1 envelope glycoproteins is dependent on membrane fusion and can be inhibited by high levels of CD4 expression

artículo científico publicado en 2003

DNA end-joining in extracts from human cells

artículo científico publicado en 1995

Decay-accelerating factor (CD55) protects human immunodeficiency virus type 1 from inactivation by human complement

artículo científico publicado en 1995

Design clues from functional constraints and broadly neutralizing antibodies

Design, synthesis and biological evaluation of small molecule inhibitors of CD4-gp120 binding based on virtual screening

artículo científico publicado en 2010

Determinants of human immunodeficiency virus type 1 entry in the CDR2 loop of the CD4 glycoprotein.

artículo científico publicado en 1995

Determinants of neutralization resistance in the envelope glycoproteins of a simian-human immunodeficiency virus passaged in vivo

artículo científico publicado en 1999

Determinants of the Higher Order Association of the Restriction Factor TRIM5α and Other Tripartite Motif (TRIM) Proteins ⬇️

artículo científico publicado el 16 de junio de 2011

Discontinuous, conserved neutralization epitopes overlapping the CD4-binding region of human immunodeficiency virus type 1 gp120 envelope glycoprotein

artículo científico publicado en 1992

Dual pathways of human immunodeficiency virus (HIV-1) envelope glycoprotein trafficking modulate the selective exclusion of uncleaved oligomers from virions

artículo científico publicado en 2020

Effects of CD4 synthetic peptides on HIV type I envelope glycoprotein function ⬇️

artículo científico publicado el 1 de septiembre de 1992

Effects of HIV Type 1 Envelope Glycoprotein Proteolytic Processing on Antigenicity ⬇️

artículo científico publicado el 1 de marzo de 2003

Effects of human TRIM5alpha polymorphisms on antiretroviral function and susceptibility to human immunodeficiency virus infection

artículo científico publicado en 2006

Effects of human immunodeficiency virus type 1 infection on programmed cell death in the presence or absence of Bcl-2.

artículo científico publicado en 1996

Effects of the I559P gp41 change on the conformation and function of the human immunodeficiency virus (HIV-1) membrane envelope glycoprotein trimer

artículo científico publicado en 2015

Effects of vif mutations on cell-free infectivity and replication of simian immunodeficiency virus.

artículo científico publicado en 1994

Effects on CD4 binding of anti-peptide sera to the fourth and fifth conserved domains of HIV-1 gp120.

artículo científico publicado en 1990

Efficient human immunodeficiency virus (HIV-1) infection of cells lacking PDZD8

artículo científico publicado en 2015

Elicitation of neutralizing antibodies with DNA vaccines expressing soluble stabilized human immunodeficiency virus type 1 envelope glycoprotein trimers conjugated to C3d.

artículo científico publicado en 2004

Energetics of the HIV gp120-CD4 binding reaction

artículo científico publicado en 2000

Enhanced autointegration in hyperstable simian immunodeficiency virus capsid mutants blocked after reverse transcription

artículo científico publicado en 2013

Enhanced expression, native purification, and characterization of CCR5, a principal HIV-1 coreceptor

artículo científico publicado en 1999

Envelope glycoprotein determinants of increased entry in a pathogenic simian-human immunodeficiency virus (SHIV-HXBc2P 3.2) passaged in monkeys

artículo científico publicado en 2004

Envelope glycoprotein determinants of neutralization resistance in a simian-human immunodeficiency virus (SHIV-HXBc2P 3.2) derived by passage in monkeys

artículo científico publicado en 2001

Epitope mapping and characterization of a novel CD4-induced human monoclonal antibody capable of neutralizing primary HIV-1 strains ⬇️

artículo científico publicado el 10 de octubre de 2003

Evidence for recombination of live, attenuated immunodeficiency virus vaccine with challenge virus to a more virulent strain.

artículo científico publicado en 2000

Evolution of a cytoplasmic tripartite motif (TRIM) protein in cows that restricts retroviral infection

artículo científico publicado en 2006

Expression of the x-lor gene of human T-cell leukemia virus I in Escherichia coli

artículo científico publicado en 1985

Factors limiting the immunogenicity of HIV-1 gp120 envelope glycoproteins

artículo científico publicado en 2004

Fine definition of a conserved CCR5-binding region on the human immunodeficiency virus type 1 glycoprotein 120

scientific article published on 01 May 2000

Fitness costs limit viral escape from cytotoxic T lymphocytes at a structurally constrained epitope

scientific article published on December 2004

Flexible use of nuclear import pathways by HIV-1.

artículo científico publicado en 2010

Folding DNA into a Lipid-Conjugated Nanobarrel for Controlled Reconstitution of Membrane Proteins

artículo científico publicado en 2017

Functional analysis of the vpx, vpr, and nef genes of simian immunodeficiency virus.

artículo científico publicado en 1995

Functional association of cyclophilin A with HIV-1 virions

artículo científico publicado en 1994

Functional interplay between the B-box 2 and the B30.2(SPRY) domains of TRIM5alpha

artículo científico publicado en 2007

Functional mimicry of a human immunodeficiency virus type 1 coreceptor by a neutralizing monoclonal antibody

artículo científico publicado en 2005

Functional replacement of the RING, B-box 2, and coiled-coil domains of tripartite motif 5alpha (TRIM5alpha) by heterologous TRIM domains

artículo científico publicado en 2006

Gene transfer into human lymphocytes by a defective human immunodeficiency virus type 1 vector

artículo científico publicado en 1991

Glycosylation and processing of the human immunodeficiency virus type 1 envelope protein

artículo científico publicado en 1989

Gp41-targeted antibodies restore infectivity of a fusion-deficient HIV-1 envelope glycoprotein

scientific article published on 11 May 2020

HIV vaccine design and the neutralizing antibody problem

artículo científico publicado en 2004

HIV-1 Adapts To Replicate in Cells Expressing Common Marmoset APOBEC3G and BST2

artículo científico publicado en 2015

HIV-1 Env gp120 structural determinants for peptide triazole dual receptor site antagonism

artículo científico publicado en 2012

HIV-1 entry and macrophage inflammatory protein-1beta-mediated signaling are independent functions of the chemokine receptor CCR5.

artículo científico publicado en 1997

HIV-1 envelope protein gp140 binding studies to human brain microvascular endothelial cells

artículo científico publicado en 2007

HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

artículo científico publicado en 2002

HIV-Host Interactions: Implications for Vaccine Design

artículo científico publicado en 2016

HTLV-I p27rex regulates gag and env protein expression.

artículo científico publicado en 1989

High degree of sensitivity of the simian immunodeficiency virus (SIVmac) envelope glycoprotein subunit association to amino acid changes in the glycoprotein 41 ectodomain

artículo científico publicado en 1997

Highly stable trimers formed by human immunodeficiency virus type 1 envelope glycoproteins fused with the trimeric motif of T4 bacteriophage fibritin

artículo científico publicado en 2002

Human Mast cell progenitors can be infected by macrophagetropic human immunodeficiency virus type 1 and retain virus with maturation in vitro

artículo científico publicado en 2001

Human and simian immunodeficiency virus capsid proteins are major viral determinants of early, postentry replication blocks in simian cells

artículo científico publicado en 2003

Human anti-V2 monoclonal antibody that neutralizes primary but not laboratory isolates of human immunodeficiency virus type 1

artículo científico publicado en 1994

Human antibody responses to HIV type 1 glycoprotein 41 cloned in phage display libraries suggest three major epitopes are recognized and give evidence for conserved antibody motifs in antigen binding

artículo científico publicado en 1996

Human immunodeficiency virus type 1 envelope glycoprotein-specific cytotoxic T lymphocytes in simian-human immunodeficiency virus-infected rhesus monkeys

artículo científico publicado en 1995

Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1

artículo científico publicado en 1996

Identification of a human immunodeficiency virus type 1 envelope glycoprotein variant resistant to cold inactivation

artículo científico publicado en 2009

Identification of a sequence required for efficient packaging of human immunodeficiency virus type 1 RNA into virions

artículo científico publicado en 1989

Identification of conserved and variable structures in the human immunodeficiency virus gp120 glycoprotein of importance for CXCR4 binding

artículo científico publicado en 2002

Identification of interdependent variables that influence coreceptor switch in R5 SHIV(SF162P3N)-infected macaques

artículo científico publicado en 2012

Identification of membrane anchorage domains of the HIV-1 gp160 envelope glycoprotein precursor

artículo científico publicado en 1991

Importance of membrane fusion mediated by human immunodeficiency virus envelope glycoproteins for lysis of primary CD4-positive T cells

artículo científico publicado en 2000

Improved elicitation of neutralizing antibodies against primary human immunodeficiency viruses by soluble stabilized envelope glycoprotein trimers

artículo científico publicado en 2001

Increased neutralization sensitivity of CD4-independent human immunodeficiency virus variants

artículo científico publicado en 2001

Induction of a Tier-1-like Phenotype in Diverse Tier-2 Isolates by Agents that Guide HIV-1 Env to Perturbation-sensitive, Non-native States

artículo científico publicado en 2017

Induction of antibodies in guinea pigs and rhesus monkeys against the human immunodeficiency virus type 1 envelope: neutralization of nonpathogenic and pathogenic primary isolate simian/human immunodeficiency virus strains

artículo científico publicado en 2000

Infection of cynomolgus monkeys with a chimeric HIV-1/SIVmac virus that expresses the HIV-1 envelope glycoproteins

artículo científico publicado el 1 de enero de 1992

Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes

artículo científico publicado en 2014

Influence of the Envelope gp120 Phe 43 Cavity on HIV-1 Sensitivity to Antibody-Dependent Cell-Mediated Cytotoxicity Responses

artículo científico publicado en 2017

Inhibiting early-stage events in HIV-1 replication by small-molecule targeting of the HIV-1 capsid

artículo científico publicado en 2012

Inhibition of human immunodeficiency virus envelope glycoprotein- mediated single cell lysis by low-molecular-weight antagonists of viral entry

artículo científico publicado en 2006

Inhibition of human immunodeficiency virus syncytium formation and virus replication by castanospermine

artículo científico publicado en 1987

Inter-subunit disulfide bonds in soluble HIV-1 envelope glycoprotein trimers.

artículo científico publicado en 2005

Interaction with cellular CD4 exposes HIV-1 envelope epitopes targeted by antibody-dependent cell-mediated cytotoxicity

scientific article published on 18 December 2013

Interactions among HIV gp120, CD4, and CXCR4: dependence on CD4 expression level, gp120 viral origin, conservation of the gp120 COOH- and NH2-termini and V1/V2 and V3 loops, and sensitivity to neutralizing antibodies.

artículo científico publicado en 1998

Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding

artículo científico publicado en 1995

Lack of correlation between soluble CD4-induced shedding of the human immunodeficiency virus type 1 exterior envelope glycoprotein and subsequent membrane fusion events ⬇️

artículo científico publicado el 1 de septiembre de 1992

Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry

artículo científico publicado en 2019

Ligand binding characteristics of CXCR4 incorporated into paramagnetic proteoliposomes

artículo científico publicado en 2001

Ligand-independent dimerization of CXCR4, a principal HIV-1 coreceptor

artículo científico publicado en 2002

Lineage-specific differences between human and simian immunodeficiency virus regulation of gp120 trimer association and CD4 binding

artículo científico publicado en 2012

Liposomes for HIV prophylaxis

artículo científico publicado en 2011

Location of the trans-activating region on the genome of human T-cell lymphotropic virus type III.

artículo científico publicado en 1985

Long terminal repeat structure of an American isolate of type I human T-cell leukemia virus

artículo científico publicado en 1984

Loss of a conserved N-linked glycosylation site in the simian immunodeficiency virus envelope glycoprotein V2 region enhances macrophage tropism by increasing CD4-independent cell-to-cell transmission

artículo científico publicado en 2014

Mapping the protein surface of human immunodeficiency virus type 1 gp120 using human monoclonal antibodies from phage display libraries

artículo científico publicado en 1997

Mechanism of leukemogenesis by human T-cell leukemia virus types I and II: role of the lor gene.

artículo científico publicado en 1987

Membrane-fusing capacity of the human immunodeficiency virus envelope proteins determines the efficiency of CD+ T-cell depletion in macaques infected by a simian-human immunodeficiency virus

artículo científico publicado en 2001

Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide.

artículo científico publicado en 2017

Mode of action for linear peptide inhibitors of HIV-1 gp120 interactions

artículo científico publicado en 2004

Mode of transmission affects the sensitivity of human immunodeficiency virus type 1 to restriction by rhesus TRIM5alpha

artículo científico publicado en 2008

Modeling virus- and antibody-specific factors to predict human immunodeficiency virus neutralization efficiency.

artículo científico publicado en 2013

Modifications that stabilize human immunodeficiency virus envelope glycoprotein trimers in solution

artículo científico publicado en 2000

Modulation of retroviral restriction and proteasome inhibitor-resistant turnover by changes in the TRIM5alpha B-box 2 domain

artículo científico publicado en 2007

Molecular cloning and analysis of functional envelope genes from human immunodeficiency virus type 1 sequence subtypes A through G. The WHO and NIAID Networks for HIV Isolation and Characterization.

artículo científico publicado en 1996

Monoclonal antibodies to HIV-1 gp120: a request

artículo científico publicado en 1993

Mutagenic stabilization and/or disruption of a CD4-bound state reveals distinct conformations of the human immunodeficiency virus type 1 gp120 envelope glycoprotein

artículo científico publicado en 2002

N-linked glycosylation in the CXCR4 N-terminus inhibits binding to HIV-1 envelope glycoproteins

artículo científico publicado en 2004

Neutralizing recombinant human antibodies to a conformational V2- and CD4-binding site-sensitive epitope of HIV-1 gp120 isolated by using an epitope-masking procedure.

artículo científico publicado en 1995

Oligomer-specific conformations of the human immunodeficiency virus (HIV-1) gp41 envelope glycoprotein ectodomain recognized by human monoclonal antibodies

artículo científico publicado en 2009

Oligomeric modeling and electrostatic analysis of the gp120 envelope glycoprotein of human immunodeficiency virus

artículo científico publicado en 2000

P09-13. Structure of HIV-1 gp41 interactive region: layered architecture and basis of conformational mobility

article

Paramagnetic proteoliposomes containing a pure, native, and oriented seven-transmembrane segment protein, CCR5.

artículo científico publicado en 2000

Perspective: research highlights at the Dana-Farber Cancer Institute Center for AIDS Research (CFAR).

artículo científico publicado en 1996

Phenotypic and immunologic comparison of clade B transmitted/founder and chronic HIV-1 envelope glycoproteins

artículo científico publicado en 2011

Potent Neutralizing Monoclonal Antibodies Directed to Multiple Epitopes on the SARS-CoV-2 Spike

artículo científico publicado en 2020

Potent neutralizing antibodies directed to multiple epitopes on SARS-CoV-2 spike

artículo científico publicado en 2020

Probability analysis of variational crystallization and its application to gp120, the exterior envelope glycoprotein of type 1 human immunodeficiency virus (HIV-1).

artículo científico publicado en 1999

Protein-coding capacities of polyadenylated RNAs from normal and neoplastic rat mammary tissues ⬇️

artículo científico publicado el 1 de abril de 1983

Proteolytic processing of the human immunodeficiency virus envelope glycoprotein precursor decreases conformational flexibility

artículo científico publicado en 2012

Rapid CD4+ T-lymphocyte depletion in rhesus monkeys infected with a simian-human immunodeficiency virus expressing the envelope glycoproteins of a primary dual-tropic Ethiopian Clade C HIV type 1 isolate

artículo científico publicado en 2004

Rapid turnover and polyubiquitylation of the retroviral restriction factor TRIM5.

artículo científico publicado en 2006

Relationship of the human immunodeficiency virus type 1 gp120 third variable loop to a component of the CD4 binding site in the fourth conserved region ⬇️

artículo científico publicado el 1 de diciembre de 1992

Release of gp120 Restraints Leads to an Entry-Competent Intermediate State of the HIV-1 Envelope Glycoproteins

artículo científico publicado en 2016

Removal of arginine 332 allows human TRIM5alpha to bind human immunodeficiency virus capsids and to restrict infection

artículo científico publicado en 2006

Repetitive structure in the long-terminal-repeat element of a type II human T-cell leukemia virus ⬇️

artículo científico publicado el 1 de agosto de 1984

Replication and pathogenesis of the human T-cell leukemia/lymphotropic retroviruses.

artículo científico publicado en 1987

Replicative and cytopathic potential of HTLV-III/LAV with sor gene deletions

artículo científico publicado en 1986

Replicative function and neutralization sensitivity of envelope glycoproteins from primary and T-cell line-passaged human immunodeficiency virus type 1 isolates.

artículo científico publicado en 1995

Requirements for capsid-binding and an effector function in TRIMCyp-mediated restriction of HIV-1.

artículo científico publicado en 2006

Rescue of human immunodeficiency virus type 1 matrix protein mutants by envelope glycoproteins with short cytoplasmic domains.

artículo científico publicado en 1995

Retroviral restriction factor TRIM5alpha is a trimer

artículo científico publicado en 2005

Retrovirus restriction by TRIM5alpha variants from Old World and New World primates

artículo científico publicado en 2005

Robustness of signal detection in cryo-electron microscopy via a bi-objective-function approach

Role of TRIM5α RING Domain E3 Ubiquitin Ligase Activity in Capsid Disassembly, Reverse Transcription Blockade, and Restriction of Simian Immunodeficiency Virus ⬇️

artículo científico publicado el 15 de junio de 2011

Role of the HTLV-III/LAV envelope in syncytium formation and cytopathicity

artículo científico publicado en 1986

Role of the gp120 inner domain beta-sandwich in the interaction between the human immunodeficiency virus envelope glycoprotein subunits

artículo científico publicado en 2003

SOSIP changes affect human immunodeficiency virus (HIV-1) envelope glycoprotein conformation and CD4 engagement

article

Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth

artículo científico publicado en 2005

Selective interactions of polyanions with basic surfaces on human immunodeficiency virus type 1 gp120

artículo científico publicado en 2000

Sequence of the Envelope Glycoprotein Gene of Type II Human T Lymphotropic Virus ⬇️

artículo científico publicado el 27 de julio de 1984

Serological cross-reactivity between envelope gene products of type I and type II human T-cell leukemia virus ⬇️

artículo científico publicado el 1 de diciembre de 1984

Short Communication: Immunogenicity of DNA Vaccines Expressing Human Immunodeficiency Virus Type 1 Envelope Glycoprotein with and without Deletions in the V1/2 and V3 Regions ⬇️

artículo científico publicado el 20 de enero de 1998

Short Communication: Small-Molecule CD4 Mimetics Sensitize HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity by Antibodies Elicited by Multiple Envelope Glycoprotein Immunogens in Nonhuman Primates.

artículo científico publicado en 2016

Simian Virus 40-Based Replication of Catalytically Inactive Human Immunodeficiency Virus Type 1 Integrase Mutants in Nonpermissive T Cells and Monocyte-Derived Macrophages.

artículo científico publicado en 2004

Simian virus 40-based replication of catalytically inactive human immunodeficiency virus type 1 integrase mutants in nonpermissive T cells and monocyte-derived macrophages

artículo científico publicado en 2004

Small CD4 Mimetics Prevent HIV-1 Uninfected Bystander CD4 + T Cell Killing Mediated by Antibody-dependent Cell-mediated Cytotoxicity

artículo científico publicado en 2015

Small-Molecule CD4-Mimics: Structure-Based Optimization of HIV-1 Entry Inhibition

artículo científico publicado en 2016

Small-molecule CD4 mimics interact with a highly conserved pocket on HIV-1 gp120.

artículo científico publicado en 2008

Solid-phase proteoliposomes containing human immunodeficiency virus envelope glycoproteins

artículo científico publicado en 2002

Solubilization, stabilization, and purification of chemokine receptors using biosensor technology

artículo científico publicado en 2005

Soluble CD4 and CD4-mimetic compounds inhibit HIV-1 infection by induction of a short-lived activated state

artículo científico publicado en 2009

Soluble mimetics of human immunodeficiency virus type 1 viral spikes produced by replacement of the native trimerization domain with a heterologous trimerization motif: characterization and ligand binding analysis

artículo científico publicado en 2005

Species-specific inhibition of foamy viruses from South American monkeys by New World Monkey TRIM5{alpha} proteins.

artículo científico publicado en 2010

Species-specific variation in the B30.2(SPRY) domain of TRIM5alpha determines the potency of human immunodeficiency virus restriction

artículo científico publicado en 2005

Species-specific, postentry barriers to primate immunodeficiency virus infection

artículo científico publicado en 1999

Specific interaction of CXCR4 with CD4 and CD8alpha: functional analysis of the CD4/CXCR4 interaction in the context of HIV-1 envelope glycoprotein-mediated membrane fusion

artículo científico publicado en 2006

Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor

artículo científico publicado en 2006

Spike glycoprotein and host cell determinants of SARS-CoV-2 entry and cytopathic effects

artículo científico publicado en 2020

Stabilization of human immunodeficiency virus type 1 envelope glycoprotein trimers by disulfide bonds introduced into the gp41 glycoprotein ectodomain

artículo científico publicado en 1998

Stimulation of enveloped virus infection by beta-amyloid fibrils

artículo científico publicado en 2002

Stoichiometry of antibody neutralization of human immunodeficiency virus type 1.

artículo científico publicado en 2005

Stoichiometry of envelope glycoprotein trimers in the entry of human immunodeficiency virus type 1

artículo científico publicado en 2005

Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

artículo científico publicado en 2010

Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

artículo científico publicado en 2009

Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120

artículo científico publicado en 2004

Structural characterization of broadly neutralizing human monoclonal antibodies against the CD4 binding site of HIV-1 gp120.

artículo científico publicado en 1994

Structural definition of a conserved neutralization epitope on HIV-1 gp120

artículo científico publicado en 2007

Structural determinants for affinity enhancement of a dual antagonist peptide entry inhibitor of human immunodeficiency virus type-1.

artículo científico publicado en 2008

Structural interactions between chemokine receptors, gp120 Env and CD4 ⬇️

artículo científico publicado el 1 de junio de 1998

Structure and function of human leukemia and AIDS viruses

scientific article published on 01 January 1984

Structure of 3′ Terminal Region of Type II Human T Lymphotropic Virus: Evidence for New Coding Region ⬇️

artículo científico publicado el 27 de julio de 1984

Structure of BMS-806, a Small-molecule HIV-1 Entry Inhibitor, Bound to BG505 SOSIP.664 HIV-1 Env Trimer.

artículo científico publicado en 2014

Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility

artículo científico publicado en 2010

Structure of a V3-containing HIV-1 gp120 core

artículo científico publicado en 2005

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody ⬇️

artículo científico publicado el 18 de junio de 1998

Structure-Based Design and Synthesis of an HIV-1 Entry Inhibitor Exploiting X-Ray and Thermodynamic Characterization

artículo científico publicado en 2013

Structure-Based Design, Synthesis, and Characterization of Dual Hotspot Small-Molecule HIV-1 Entry Inhibitors

artículo científico publicado en 2012

Structure-based design, synthesis and validation of CD4-mimetic small molecule inhibitors of HIV-1 entry: conversion of a viral entry agonist to an antagonist.

artículo científico publicado en 2014

Structure-based, targeted deglycosylation of HIV-1 gp120 and effects on neutralization sensitivity and antibody recognition.

artículo científico publicado en 2003

Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates

artículo científico publicado en 2000

Structures of the CCR5 N Terminus and of a Tyrosine-Sulfated Antibody with HIV-1 gp120 and CD4

artículo científico publicado en 2007

Subcellular localization of the product of the long open reading frame of human T-cell leukemia virus type I.

artículo científico publicado en 1985

Subunit organization of the membrane-bound HIV-1 envelope glycoprotein trimer

artículo científico publicado en 2012

Subunit stoichiometry of human immunodeficiency virus type 1 envelope glycoprotein trimers during virus entry into host cells

artículo científico publicado en 2006

Synergistic Neutralization of Simian-Human Immunodeficiency Virus SHIV-vpu+by Triple and Quadruple Combinations of Human Monoclonal Antibodies and High-Titer Anti-Human Immunodeficiency Virus Type 1 Immunoglobulins ⬇️

artículo científico publicado el 1 de abril de 1998

Synergistic neutralization of a chimeric SIV/HIV type 1 virus with combinations of human anti-HIV type 1 envelope monoclonal antibodies or hyperimmune globulins

artículo científico publicado en 1997

TRIM5alpha Modulates Immunodeficiency Virus Control in Rhesus Monkeys

artículo científico publicado en 2010

TRIM5alpha association with cytoplasmic bodies is not required for antiretroviral activity

artículo científico publicado en 2005

TRIM5alpha mediates the postentry block to N-tropic murine leukemia viruses in human cells

scholarly article

Target cell type-dependent modulation of human immunodeficiency virus type 1 capsid disassembly by cyclophilin A.

artículo científico publicado en 2009

Targeting a foreign protein into virion particles by fusion with the Vpx protein of simian immunodeficiency virus

artículo científico publicado en 1996

Tat protein induces human immunodeficiency virus type 1 (HIV-1) coreceptors and promotes infection with both macrophage-tropic and T-lymphotropic HIV-1 strains

artículo científico publicado en 1998

The B30.2(SPRY) domain of the retroviral restriction factor TRIM5alpha exhibits lineage-specific length and sequence variation in primates

artículo científico publicado en 2005

The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens ⬇️

artículo científico publicado el 19 de junio de 1998

The HIV-1 gp120 major variable regions modulate cold inactivation

artículo científico publicado en 2013

The Orphan Seven-Transmembrane Receptor Apj Supports the Entry of Primary T-Cell-Line-Tropic and Dualtropic Human Immunodeficiency Virus Type 1 ⬇️

artículo científico publicado el 1 de julio de 1998

The TRIM5alpha B-box 2 domain promotes cooperative binding to the retroviral capsid by mediating higher-order self-association

artículo científico publicado en 2008

The ability of multimerized cyclophilin A to restrict retrovirus infection

artículo científico publicado en 2007

The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates

artículo científico publicado en 1996

The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus.

artículo científico publicado en 2008

The contribution of RING and B-box 2 domains to retroviral restriction mediated by monkey TRIM5alpha

artículo científico publicado en 2005

The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys

artículo científico publicado en 2004

The highly conserved layer-3 component of the HIV-1 gp120 inner domain is critical for CD4-required conformational transitions.

artículo científico publicado en 2012

The human T-cell leukemia virus (HTLV) transactivator (Tax) protein

artículo científico publicado el 14 de septiembre de 1992

The human TRIM5alpha restriction factor mediates accelerated uncoating of the N-tropic murine leukemia virus capsid

artículo científico publicado en 2006

The impact of envelope glycoprotein cleavage on the antigenicity, infectivity, and neutralization sensitivity of Env-pseudotyped human immunodeficiency virus type 1 particles

artículo científico publicado en 2005

The level of CD4 expression limits infection of primary rhesus monkey macrophages by a T-tropic simian immunodeficiency virus and macrophagetropic human immunodeficiency viruses

artículo científico publicado en 2000

The lor gene and pathogenesis of HTLV-I, -II, and -III.

artículo científico publicado en 1985

The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

artículo científico publicado en 1996

The potential for homeostatic regulation of the X region proteins of the human T cell leukemia virus type I.

artículo científico publicado en 1989

The selection of low envelope glycoprotein reactivity to soluble CD4 and cold during simian-human immunodeficiency virus infection of rhesus macaques.

artículo científico publicado en 2013

Thermal stability of the human immunodeficiency virus type 1 (HIV-1) receptors, CD4 and CXCR4, reconstituted in proteoliposomes

artículo científico publicado en 2010

Thermodynamics of binding of a low-molecular-weight CD4 mimetic to HIV-1 gp120.

artículo científico publicado en 2006

Topological layers in the HIV-1 gp120 inner domain regulate gp41 interaction and CD4-triggered conformational transitions

artículo científico publicado en 2010

Towards a structure of the HIV-1 envelope glycoprotein gp120: an immunochemical approach

scientific article published on 01 October 1993

Trafficking of some old world primate TRIM5α proteins through the nucleus ⬇️

artículo científico publicado el 15 de mayo de 2011

Trans-acting transcriptional regulation of human T-cell leukemia virus type III long terminal repeat

artículo científico publicado en 1985

Transitions to and from the CD4-bound conformation are modulated by a single-residue change in the human immunodeficiency virus type 1 gp120 inner domain

artículo científico publicado en 2009

Two Orphan Seven-Transmembrane Segment Receptors Which Are Expressed in CD4-positive Cells Support Simian Immunodeficiency Virus Infection ⬇️

artículo científico publicado el 4 de agosto de 1997

Two surface-exposed elements of the B30.2/SPRY domain as potency determinants of N-tropic murine leukemia virus restriction by human TRIM5alpha

artículo científico publicado en 2006

Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry

artículo científico publicado en 1999

Tyrosine-sulfated peptides functionally reconstitute a CCR5 variant lacking a critical amino-terminal region

artículo científico publicado en 2002

Understanding the basis of CD4(+) T-cell depletion in macaques infected by a simian-human immunodeficiency virus

artículo científico publicado en 2002

Unique features of TRIM5alpha among closely related human TRIM family members

artículo científico publicado en 2007

Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops

artículo científico publicado en 2012

Use of Murine CXCR-4 as a Second Receptor by Some T-Cell-Tropic Human Immunodeficiency Viruses ⬇️

artículo científico publicado el 1 de febrero de 1998

Use of cis- and trans-acting viral regulatory sequences to improve expression of human immunodeficiency virus vectors in human lymphocytes

artículo científico publicado en 1996

Virus-specific effects of TRIM5α(rh) RING domain functions on restriction of retroviruses.

artículo científico publicado en 2013

trans-Activation of the human T-cell leukemia virus long terminal repeat correlates with expression of the x-lor protein

artículo científico publicado en 1985

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