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Lista de obras de Carlos Opazo

A novel functional low-density lipoprotein receptor-related protein 6 gene alternative splice variant is associated with Alzheimer's disease.

artículo científico

Acetylcholinesterase promotes the aggregation of amyloid-beta-peptide fragments by forming a complex with the growing fibrils.

artículo científico publicado en 1997

Alzheimer disease beta-amyloid activity mimics cholesterol oxidase

artículo científico publicado en 2005

Alzheimer's Aβ interacts with cellular prion protein inducing neuronal membrane damage and synaptotoxicity

artículo científico publicado en 2014

Beta-amyloid causes depletion of synaptic vesicles leading to neurotransmission failure

artículo científico publicado en 2009

Biphasic effects of copper on neurotransmission in rat hippocampal neurons.

artículo científico publicado en 2011

Blood and brain protein levels of ubiquitin-conjugating enzyme E2K (UBE2K) are elevated in individuals with schizophrenia

artículo científico publicado en 2019

Canonical Wnt3a modulates intracellular calcium and enhances excitatory neurotransmission in hippocampal neurons

scientific journal article

Copper-uptake is critical for the down regulation of synapsin and dynamin induced by neocuproine: modulation of synaptic activity in hippocampal neurons.

artículo científico publicado en 2014

Copper: from neurotransmission to neuroproteostasis

artículo científico publicado en 2014

Crosslinking of amyloid-beta peptide to brain acetylcholinesterase.

artículo científico publicado en 1998

Cysteine 144 is a key residue in the copper reduction by the beta-amyloid precursor protein

artículo científico publicado en 1999

Differential Membrane Toxicity of Amyloid-β Fragments by Pore Forming Mechanisms.

artículo científico publicado en 2016

Elevated ubiquitinated proteins in brain and blood of individuals with schizophrenia

scientific article published on 19 February 2019

Extracellular α-synuclein alters synaptic transmission in brain neurons by perforating the neuronal plasma membrane.

artículo científico publicado en 2015

Features of alpha-synuclein that could explain the progression and irreversibility of Parkinson's disease

artículo científico publicado en 2015

Fibrinogen nitrotyrosination after ischemic stroke impairs thrombolysis and promotes neuronal death

artículo científico publicado en 2014

Ibuprofen inhibits the synaptic failure induced by the amyloid-β peptide in hippocampal neurons.

artículo científico publicado en 2013

Intracellular amyloid formation in muscle cells of Abeta-transgenic Caenorhabditis elegans: determinants and physiological role in copper detoxification

artículo científico publicado en 2009

Low concentrations of ethanol protect against synaptotoxicity induced by Aβ in hippocampal neurons.

artículo científico publicado en 2014

Metallo-pathways to Alzheimer's disease: lessons from genetic disorders of copper trafficking

artículo científico publicado en 2016

Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2).

artículo científico publicado en 2002

Nature of the neurotoxic membrane actions of amyloid-β on hippocampal neurons in Alzheimer's disease.

artículo científico publicado en 2013

On stage single cell identification of rat spermatogenic cells.

artículo científico publicado en 1997

Overrepresentation of glutamate signaling in Alzheimer's disease: network-based pathway enrichment using meta-analysis of genome-wide association studies.

artículo científico publicado en 2014

PSD95 suppresses dendritic arbor development in mature hippocampal neurons by occluding the clustering of NR2B-NMDA receptors.

artículo científico publicado en 2014

Radioiodinated clioquinol as a biomarker for beta-amyloid: Zn complexes in Alzheimer's disease

artículo científico publicado en 2006

Rapamycin protects against Aβ-induced synaptotoxicity by increasing presynaptic activity in hippocampal neurons.

artículo científico publicado en 2014

Soluble Aβ(1-40) peptide increases excitatory neurotransmission and induces epileptiform activity in hippocampal neurons.

artículo científico publicado en 2011

Synaptotoxicity of Alzheimer beta amyloid can be explained by its membrane perforating property

artículo científico publicado en 2010

The N-terminal copper-binding domain of the amyloid precursor protein protects against Cu2+ neurotoxicity in vivo.

artículo científico publicado en 2004

The pathophysiology of axonal transport in Alzheimer's disease

artículo científico publicado en 2015

Wnt/β-catenin signaling stimulates the expression and synaptic clustering of the autism-associated Neuroligin 3 gene

artículo científico publicado en 2018