Lista de obras - Stefano Morotti - Dominio Público Uruguay

A Heart for Diversity: Simulating Variability in Cardiac Arrhythmia Research

artículo científico publicado en 2018

A computational model of induced pluripotent stem-cell derived cardiomyocytes incorporating experimental variability from multiple data sources

artículo científico publicado en 2019

A novel computational model of mouse myocyte electrophysiology to assess the synergy between Na+ loading and CaMKII.

artículo científico publicado en 2014

Adenylyl cyclase 5-generated cAMP controls cerebral vascular reactivity during diabetic hyperglycemia

scientific article published on 04 June 2019

Atrial-selective targeting of arrhythmogenic phase-3 early afterdepolarizations in human myocytes

artículo científico publicado en 2015

Bi-directional flow of the funny current (I f ) during the pacemaking cycle in murine sinoatrial node myocytes

Ca(2+) current facilitation is CaMKII-dependent and has arrhythmogenic consequences

artículo científico publicado en 2014

Different paths, same destination: divergent action potential responses produce conserved cardiac fight-or-flight response in mouse and rabbit hearts

scientific article published on 11 July 2019

Editorial: Safety Pharmacology - Risk Assessment QT Interval Prolongation and Beyond.

artículo científico publicado en 2018

Erratum: "Revealing kinetics and state-dependent binding properties of IKur-targeting drugs that maximize atrial fibrillation selectivity" [Chaos 27, 093918 (2017)].

artículo científico publicado en 2017

FRET biosensor uncovers cAMP nano-domains at β-adrenergic targets that dictate precise tuning of cardiac contractility

artículo científico publicado en 2017

In Silico Assessment of Efficacy and Safety of IKur Inhibitors in Chronic Atrial Fibrillation: Role of Kinetics and State-Dependence of Drug Binding. ⬇️

artículo científico publicado en 2017

Interplay of voltage and Ca-dependent inactivation of L-type Ca current.

artículo científico publicado en 2010

Inward Rectifier Potassium Channels (Kir2.x) and Caveolin-3 Domain-Specific Interaction: Implications for Purkinje Cell-Dependent Ventricular Arrhythmias.

artículo científico publicado en 2018

Logistic regression analysis of populations of electrophysiological models to assess proarrythmic risk

scientific article published on 23 December 2016

Predominant contribution of L-type Cav1.2 channel stimulation to impaired intracellular calcium and cerebral artery vasoconstriction in diabetic hyperglycemia.

artículo científico publicado en 2017

Quantitative analysis of the Ca2+ -dependent regulation of delayed rectifier K+ current IKs in rabbit ventricular myocytes

artículo científico publicado en 2016

Quantitative systems models illuminate arrhythmia mechanisms in heart failure: Role of the Na+ -Ca2+ -Ca2+ /calmodulin-dependent protein kinase II-reactive oxygen species feedback

scientific article published on 17 July 2018

Revealing kinetics and state-dependent binding properties of IKur-targeting drugs that maximize atrial fibrillation selectivity.

artículo científico publicado en 2017

Ser1928 phosphorylation by PKA stimulates the L-type Ca2+ channel CaV1.2 and vasoconstriction during acute hyperglycemia and diabetes.

artículo científico publicado en 2017

β-adrenergic effects on cardiac myofilaments and contraction in an integrated rabbit ventricular myocyte model

artículo científico publicado en 2015

Lista de obras de Stefano Morotti

A Heart for Diversity: Simulating Variability in Cardiac Arrhythmia Research

A computational model of induced pluripotent stem-cell derived cardiomyocytes incorporating experimental variability from multiple data sources

A novel computational model of mouse myocyte electrophysiology to assess the synergy between Na+ loading and CaMKII.

Adenylyl cyclase 5-generated cAMP controls cerebral vascular reactivity during diabetic hyperglycemia

Atrial-selective targeting of arrhythmogenic phase-3 early afterdepolarizations in human myocytes

Bi-directional flow of the funny current (I f ) during the pacemaking cycle in murine sinoatrial node myocytes

Ca(2+) current facilitation is CaMKII-dependent and has arrhythmogenic consequences

Different paths, same destination: divergent action potential responses produce conserved cardiac fight-or-flight response in mouse and rabbit hearts

Editorial: Safety Pharmacology - Risk Assessment QT Interval Prolongation and Beyond.

Erratum: "Revealing kinetics and state-dependent binding properties of IKur-targeting drugs that maximize atrial fibrillation selectivity" [Chaos 27, 093918 (2017)].

FRET biosensor uncovers cAMP nano-domains at β-adrenergic targets that dictate precise tuning of cardiac contractility

In Silico Assessment of Efficacy and Safety of IKur Inhibitors in Chronic Atrial Fibrillation: Role of Kinetics and State-Dependence of Drug Binding. ⬇️

Interplay of voltage and Ca-dependent inactivation of L-type Ca current.

Inward Rectifier Potassium Channels (Kir2.x) and Caveolin-3 Domain-Specific Interaction: Implications for Purkinje Cell-Dependent Ventricular Arrhythmias.

Logistic regression analysis of populations of electrophysiological models to assess proarrythmic risk

Predominant contribution of L-type Cav1.2 channel stimulation to impaired intracellular calcium and cerebral artery vasoconstriction in diabetic hyperglycemia.

Quantitative analysis of the Ca2+ -dependent regulation of delayed rectifier K+ current IKs in rabbit ventricular myocytes

Quantitative systems models illuminate arrhythmia mechanisms in heart failure: Role of the Na+ -Ca2+ -Ca2+ /calmodulin-dependent protein kinase II-reactive oxygen species feedback

Revealing kinetics and state-dependent binding properties of IKur-targeting drugs that maximize atrial fibrillation selectivity.

Ser1928 phosphorylation by PKA stimulates the L-type Ca2+ channel CaV1.2 and vasoconstriction during acute hyperglycemia and diabetes.

β-adrenergic effects on cardiac myofilaments and contraction in an integrated rabbit ventricular myocyte model