Lista de obras - John Knight - Dominio Público Uruguay

A Deacetylase-Deficient SIRT1 Variant Opposes Full-Length SIRT1 in Regulating Tumor Suppressor p53 and Governs Expression of Cancer-Related Genes ⬇️

artículo científico publicado el 28 de noviembre de 2011

A common polymorphism in the 5' UTR of ERCC5 creates an upstream ORF that confers resistance to platinum-based chemotherapy

artículo científico publicado en 2015

Active regulator of SIRT1 is required for cancer cell survival but not for SIRT1 activity

artículo científico publicado en 2013

Active regulator of SIRT1 is required for ribosome biogenesis and function.

artículo científico publicado en 2013

Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas

artículo científico publicado en 2019

Calcium signalling links MYC to NUAK1.

artículo científico publicado en 2017

Control of translation in the cold: implications for therapeutic hypothermia.

artículo científico

Cooling-induced SUMOylation of EXOSC10 down-regulates ribosome biogenesis.

artículo científico publicado en 2016

Cyclin E is recruited to the nuclear matrix during differentiation, but is not recruited in cancer cells.

artículo científico publicado en 2010

Eukaryotic Elongation Factor 2 Kinase Activity Is Required for the Phenotypes of the Rpl24 Mouse

artículo científico publicado en 2022

Eukaryotic elongation factor 2 kinase regulates the cold stress response by slowing translation elongation.

artículo científico publicado en 2015

Hypoxic cancer–associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling

artículo científico publicado en 2019

Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD(H)-dependent and (ii) p53-independent pathways

artículo científico publicado en 2014

MNK inhibition sensitizes KRAS-mutant colorectal cancer to mTORC1 inhibition by reducing eIF4E phosphorylation and c-MYC expression

artículo científico publicado en 2020

RTN3 Is a Novel Cold-Induced Protein and Mediates Neuroprotective Effects of RBM3.

artículo científico publicado en 2017

SIRT1, metabolism and cancer ⬇️

artículo científico publicado el 1 de enero de 2012

Suboptimal T-cell receptor signaling compromises protein translation, ribosome biogenesis, and proliferation of mouse CD8 T cells

artículo científico

The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer

scientific article published on 07 January 2021

The chaperonin CCT interacts with and mediates the correct folding and activity of three subunits of translation initiation factor eIF3: b, i and h.

artículo científico publicado en 2014

Transient association of MCM complex proteins with the nuclear matrix during initiation of mammalian DNA replication

artículo científico publicado en 2015

p58IPK is an inhibitor of the eIF2α kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacity

artículo científico publicado en 2015

Lista de obras de John Knight

A Deacetylase-Deficient SIRT1 Variant Opposes Full-Length SIRT1 in Regulating Tumor Suppressor p53 and Governs Expression of Cancer-Related Genes ⬇️

A common polymorphism in the 5' UTR of ERCC5 creates an upstream ORF that confers resistance to platinum-based chemotherapy

Active regulator of SIRT1 is required for cancer cell survival but not for SIRT1 activity

Active regulator of SIRT1 is required for ribosome biogenesis and function.

Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas

Calcium signalling links MYC to NUAK1.

Control of translation in the cold: implications for therapeutic hypothermia.

Cooling-induced SUMOylation of EXOSC10 down-regulates ribosome biogenesis.

Cyclin E is recruited to the nuclear matrix during differentiation, but is not recruited in cancer cells.

Eukaryotic Elongation Factor 2 Kinase Activity Is Required for the Phenotypes of the Rpl24 Mouse

Eukaryotic elongation factor 2 kinase regulates the cold stress response by slowing translation elongation.

Hypoxic cancer–associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling

Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD(H)-dependent and (ii) p53-independent pathways

MNK inhibition sensitizes KRAS-mutant colorectal cancer to mTORC1 inhibition by reducing eIF4E phosphorylation and c-MYC expression

RTN3 Is a Novel Cold-Induced Protein and Mediates Neuroprotective Effects of RBM3.

SIRT1, metabolism and cancer ⬇️

Suboptimal T-cell receptor signaling compromises protein translation, ribosome biogenesis, and proliferation of mouse CD8 T cells

The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer

The chaperonin CCT interacts with and mediates the correct folding and activity of three subunits of translation initiation factor eIF3: b, i and h.

Transient association of MCM complex proteins with the nuclear matrix during initiation of mammalian DNA replication

p58IPK is an inhibitor of the eIF2α kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacity