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Lista de obras de Barbara Bohle

100 years of immunotherapy: the Monaco charter. under the high patronage of His Serene Highness Prince Albert II of Monaco

artículo científico publicado en 2012

126 Creation of a Humanized Model for Respiratory Allergy Using a Human Mugwort-specificT-Cell Receptor and HLA-DR1.

artículo científico publicado en 2012

3-Layer-based analysis of peptide-MHC interaction: in silico prediction, peptide binding affinity and T cell activation in a relevant allergen-specific model.

artículo científico publicado en 2009

4(th) European Congress of Immunology - ECI 2015: Vienna, September 6-9, 2015.

artículo científico publicado en 2015

4-1BB costimulation promotes bystander activation of human CD8 T cells

artículo científico publicado en 2020

6th International Symposium on Molecular Allergology (ISMA).

artículo científico publicado en 2016

A food matrix reduces digestion and absorption of food allergens in vivo

artículo científico publicado en 2011

A human monoclonal IgE antibody defines a highly allergenic fragment of the major timothy grass pollen allergen, Phl p 5: molecular, immunological, and structural characterization of the epitope-containing domain.

artículo científico publicado en 2000

A hypoallergenic variant of the major birch pollen allergen shows distinct characteristics in antigen processing and T-cell activation

scientific article published on 13 September 2012

A novel approach to specific allergy treatment: the recombinant allergen-S-layer fusion protein rSbsC-Bet v 1 matures dendritic cells that prime Th0/Th1 and IL-10-producing regulatory T cells

artículo científico publicado en 2007

A novel approach to specific allergy treatment: the recombinant fusion protein of a bacterial cell surface (S-layer) protein and the major birch pollen allergen Bet v 1 (rSbsC-Bet v 1) combines reduced allergenicity with immunomodulating capacity.

artículo científico publicado en 2004

A novel role for neutrophils in IgE-mediated allergy: Evidence for antigen presentation in late-phase reactions

artículo científico publicado en 2018

A recombinant bacterial cell surface (S-layer)-major birch pollen allergen-fusion protein (rSbsC/Bet v1) maintains the ability to self-assemble into regularly structured monomolecular lattices and the functionality of the allergen.

artículo científico publicado en 2002

A sensitive assay for the detection of IgE bound to the major birch pollen allergen, Bet v 1, in the form of immune complexes

artículo científico publicado en 2009

AIC. Dynavax

artículo científico publicado en 2003

Allergen hybrids - next generation vaccines for Fagales pollen immunotherapy

artículo científico publicado en 2014

Allergen microarray: comparison of microarray using recombinant allergens with conventional diagnostic methods to detect allergen-specific serum immunoglobulin E.

artículo científico publicado en 2003

Allergen-specific IgE production of committed B cells from allergic patients in vitro

artículo científico publicado en 1995

Allergen-specific T lymphocytes as targets for specific immunotherapy: striking at the roots of type I allergy.

artículo científico publicado en 2002

AllergenOnline: A peer-reviewed, curated allergen database to assess novel food proteins for potential cross-reactivity

artículo científico

Allergy immunotherapy across the life cycle to promote active and healthy ageing: from research to policies: An AIRWAYS Integrated Care Pathways (ICPs) programme item (Action Plan B3 of the European Innovation Partnership on active and healthy [...]

artículo científico publicado en 2016

Allergy multivaccines created by DNA shuffling of tree pollen allergens

artículo científico publicado en 2007

Allergy to millet: another risk for atopic bird keepers

artículo científico publicado en 2003

Alpha-Gal on bioprostheses: xenograft immune response in cardiac surgery.

artículo científico publicado en 2005

Alum triggers infiltration of human neutrophils ex vivo and causes lysosomal destabilization and mitochondrial membrane potential-dependent NET-formation

artículo científico publicado en 2020

Alum-adjuvanted allergoids induce functional IgE-blocking antibodies

artículo científico publicado en 2018

Amb a 1 isoforms: Unequal siblings with distinct immunological features.

artículo científico publicado en 2017

Anaphylaxis to buckwheat in an atopic child: a risk factor for severe allergy to nuts and seeds?

artículo científico publicado en 2011

Antigen presentation of the immunodominant T-cell epitope of the major mugwort pollen allergen, Art v 1, is associated with the expression of HLA-DRB1 *01.

artículo científico publicado en 2005

Apple allergy across Europe: how allergen sensitization profiles determine the clinical expression of allergies to plant foods

artículo científico publicado en 2006

Assessing protein immunogenicity with a dendritic cell line-derived endolysosomal degradome

artículo científico publicado en 2011

Assessment of Bet v 1-specific CD4+ T cell responses in allergic and nonallergic individuals using MHC class II peptide tetramers

article

Association of HLA-DR1 with the allergic response to the major mugwort pollen allergen: molecular background.

artículo científico publicado en 2012

B cell-derived exosomes can present allergen peptides and activate allergen-specific T cells to proliferate and produce TH2-like cytokines

artículo científico publicado en 2007

Bet v 1 and homologous food allergens are similarly processed by antigen-presenting cells but differ in T cell reactivity

Bet v 1, the major birch pollen allergen, and Mal d 1, the major apple allergen, cross-react at the level of allergen-specific T helper cells

artículo científico publicado en 1998

Bet v 1, the major birch pollen allergen, conjugated to crystalline bacterial cell surface proteins, expands allergen-specific T cells of the Th1/Th0 phenotype in vitro by induction of IL-12.

artículo científico publicado en 1997

Bet v 1, the major birch pollen allergen, initiates sensitization to Api g 1, the major allergen in celery: evidence at the T cell level

artículo científico publicado en 2003

Bet v 1--a Trojan horse for small ligands boosting allergic sensitization?

artículo científico publicado en 2014

Bet v 1-specific T-cell receptor/forkhead box protein 3 transgenic T cells suppress Bet v 1-specific T-cell effector function in an activation-dependent manner.

artículo científico publicado en 2011

Bet v 1142-156 is the dominant T-cell epitope of the major birch pollen allergen and important for cross-reactivity with Bet v 1-related food allergens

artículo científico publicado en 2005

Biodegradable PLGA particles for improved systemic and mucosal treatment of Type I allergy.

artículo científico publicado en 2006

Biomarkers for monitoring clinical efficacy of allergen immunotherapy for allergic rhinoconjunctivitis and allergic asthma: an EAACI Position Paper.

artículo científico publicado en 2017

Birch pollen allergen-specific immunotherapy with glutaraldehyde-modified allergoid induces IL-10 secretion and protective antibody responses

scientific article published on 11 April 2019

Birch pollen-related food allergy: clinical aspects and the role of allergen-specific IgE and IgG4 antibodies

artículo científico publicado en 2011

Blocking antibodies induced by allergen-specific immunotherapy ameliorate allergic airway disease in a human/mouse chimeric model.

artículo científico publicado en 2017

Characterization of HLA class II/peptide-TCR interactions of the immunodominant T cell epitope in Art v 1, the major mugwort pollen allergen.

artículo científico publicado en 2008

Characterization of T cell responses to Hev b 3, an allergen associated with latex allergy in spina bifida patients.

artículo científico publicado en 2000

Characterization of autoreactive T cells to the autoantigens heterogeneous nuclear ribonucleoprotein A2 (RA33) and filaggrin in patients with rheumatoid arthritis

artículo científico publicado en 2002

Characterization of recombinant Mal d 4 and its application for component-resolved diagnosis of apple allergy

artículo científico publicado en 2006

Characterization of recombinant cat albumin

artículo científico publicado en 2003

Characterization of the T cell response to the major hazelnut allergen, Cor a 1.04: evidence for a relevant T cell epitope not cross-reactive with homologous pollen allergens.

artículo científico publicado en 2005

Characterization of the T-cell response to Dau c 1, the Bet v 1-homolog in carrot

artículo científico publicado en 2016

Characterization of the allergic T-cell response to Pru p 3, the nonspecific lipid transfer protein in peach

artículo científico publicado en 2009

Characterization of the human T cell response to antigen 5 from Vespula vulgaris (Ves v 5).

artículo científico publicado en 2005

Characterization of wild-type recombinant Bet v 1a as a candidate vaccine against birch pollen allergy.

artículo científico publicado en 2005

Component-resolved in vitro diagnosis in carrot allergy: does the use of recombinant carrot allergens improve the reliability of the diagnostic procedure?

artículo científico publicado en 2005

Conserved sequence motifs of CDR3 loops of TCR specific for two major epitopes of the grass pollen allergen PhI p 1

artículo científico publicado en 1998

Context matters: T2 polarization resulting from pollen composition and not from protein-intrinsic allergenicity

article

Cooking birch pollen-related food: divergent consequences for IgE- and T cell-mediated reactivity in vitro and in vivo.

artículo científico publicado en 2006

Correlation of sensitizing capacity and T-cell recognition within the Bet v 1 family.

artículo científico publicado en 2015

CpG motifs as possible adjuvants for the treatment of allergic diseases.

artículo científico publicado en 2002

Creation of an engineered APC system to explore and optimize the presentation of immunodominant peptides of major allergens

artículo científico publicado en 2016

Critical role of mammalian target of rapamycin for IL-10 dendritic cell induction by a flagellin A conjugate in preventing allergic sensitization.

artículo científico publicado en 2017

Derangement of apoptosis-related lymphocyte homeostasis in systemic sclerosis

scientific article published on 01 December 2000

Differences in the intrinsic immunogenicity and allergenicity of Bet v 1 and related food allergens revealed by site-directed mutagenesis

artículo científico publicado en 2013

Differential activation of dendritic cells by toll-like receptors causes diverse differentiation of naïve CD4+ T cells from allergic patients.

artículo científico publicado en 2014

Differential storage of hydroxyethyl starch (HES) in the skin: an immunoelectron-microscopical long-term study.

artículo científico publicado en 2001

Dramatically decreased T cell responses but persistent IgE upon reduced pollen exposure

artículo científico publicado en 2019

EAACI Molecular Allergology User's Guide

artículo científico publicado en 2016

EAACI: A European Declaration on Immunotherapy. Designing the future of allergen specific immunotherapy

artículo científico publicado en 2012

Efficacy and safety of 4 months of sublingual immunotherapy with recombinant Mal d 1 and Bet v 1 in patients with birch pollen-related apple allergy.

artículo científico publicado en 2017

Endolysosomal protease susceptibility of Amb a 1 as a determinant of allergenicity

scientific article published on 20 November 2017

Enhanced Pru p 3 IgE-binding activity by selective free fatty acid-interaction.

artículo científico publicado en 2017

Erratum to: Risk and safety requirements for diagnostic and therapeutic procedures in allergology: World Allergy Organization Statement

artículo científico publicado en 2017

Expression and Characterization of Functional Recombinant Bet v 1.0101 in the Chloroplast of Chlamydomonas reinhardtii.

artículo científico publicado en 2017

Expression of a Major Plant Allergen as Membrane-Anchored and Secreted Protein in Human Cells with Preserved T Cell and B Cell Epitopes

article

Expression of an endotoxin-free S-layer/allergen fusion protein in gram-positive Bacillus subtilis 1012 for the potential application as vaccines for immunotherapy of atopic allergy.

artículo científico publicado en 2011

Factors influencing the allergenicity and adjuvanticity of allergens.

artículo científico publicado en 2011

FcepsilonRI engagement of Langerhans cell-like dendritic cells and inflammatory dendritic epidermal cell-like dendritic cells induces chemotactic signals and different T-cell phenotypes in vitro

artículo científico publicado en 2004

Flow cytometric analysis of cytokine expression in short-term allergen-stimulated T cells mirrors the phenotype of proliferating T cells in long-term cultures

artículo científico publicado en 2011

Fusion proteins of flagellin and the major birch pollen allergen Bet v 1 show enhanced immunogenicity, reduced allergenicity, and intrinsic adjuvanticity

artículo científico publicado en 2017

Gastrointestinal digestion of Bet v 1-homologous food allergens destroys their mediator-releasing, but not T cell-activating, capacity

artículo científico publicado en 2005

Genetic restriction of antigen-presentation dictates allergic sensitization and disease in humanized mice.

artículo científico publicado en 2018

Glutathione-S-transferase: a minor allergen in birch pollen due to limited release from hydrated pollen

artículo científico publicado en 2014

Glutathione-s-transferase is a minor allergen in birch pollen because of restricted release from hydrated pollen grains

artículo científico publicado en 2014

HLA class II peptide tetramers vs allergen-induced proliferation for identification of allergen-specific CD4 T cells

artículo científico publicado en 2014

Harmonization of the Genetic Code Effectively Enhances the Recombinant Production of the Major Birch Pollen Allergen Bet v 1

artículo científico publicado en 2018

Histone deacetylases 1 and 2 restrain CD4+ cytotoxic T lymphocyte differentiation

artículo científico publicado en 2020

Hom s 4, an IgE-reactive autoantigen belonging to a new subfamily of calcium-binding proteins, can induce Th cell type 1-mediated autoreactivity

artículo científico publicado en 2005

Human TCR transgenic Bet v 1-specific Th1 cells suppress the effector function of Bet v 1-specific Th2 cells

artículo científico publicado en 2011

Human Th2 but not Th9 cells release IL-31 in a STAT6/NF-κB-dependent way.

artículo científico

Human blood basophils do not act as antigen-presenting cells for the major birch pollen allergen Bet v 1

artículo científico publicado en 2011

Humoral and Cellular Cross-Reactivity between Amb a 1, the Major Ragweed Pollen Allergen, and Its Mugwort Homolog Art v 6

artículo científico publicado en 2011

Hydrocortisone enhances total IgE levels--but not the synthesis of allergen-specific IgE--in a monocyte-dependent manner

artículo científico publicado en 1995

IFN-gamma-enhanced allergen penetration across respiratory epithelium augments allergic inflammation

artículo científico publicado en 2005

IL-12p70-dependent Th1 induction by human B cells requires combined activation with CD40 ligand and CpG DNA.

artículo científico

IgE and allergen-specific immunotherapy-induced IgG4 recognize similar epitopes of Bet v 1, the major allergen of birch pollen.

artículo científico publicado en 2016

IgE-blocking antibodies following SLIT with recombinant Mal d 1 accord with improved apple allergy

scientific article published on 04 April 2020

IgE-mediated immediate-type hypersensitivity to the pyrazolone drug propyphenazone.

artículo científico publicado en 2003

IgE‐cross‐blocking antibodies to <i>Fagales</i> following sublingual immunotherapy with recombinant Bet v 1

artículo científico publicado en 2021

Immunological differences between insect venom-allergic patients with and without immunotherapy and asymptomatically sensitized subjects.

artículo científico publicado en 2017

Immunological mechanisms in sublingual immunotherapy

artículo científico publicado en 2008

Improving diagnostic tests for food allergy with recombinant allergens

artículo científico publicado en 2004

Initiating yellow jacket venom immunotherapy with a 100-μg dose: A challenge?

artículo científico publicado en 2018

Interaction of allergens, major histocompatibility complex molecules, and T cell receptors: a 'ménage à trois' that opens new avenues for therapeutic intervention in type I allergy

artículo científico publicado en 2011

Interleukin-10 inhibits burst-forming unit-erythroid growth by suppression of endogenous granulocyte-macrophage colony-stimulating factor production from T cells

artículo científico publicado en 1999

Interleukin-10 inhibits spontaneous colony-forming unit-granulocyte-macrophage growth from human peripheral blood mononuclear cells by suppression of endogenous granulocyte-macrophage colony-stimulating factor release.

artículo científico publicado en 1997

Intranasal treatment with a recombinant hypoallergenic derivative of the major birch pollen allergen Bet v 1 prevents allergic sensitization and airway inflammation in mice.

artículo científico publicado en 2001

Kinetics, cross-reactivity, and specificity of Bet v 1-specific IgG4 antibodies induced by immunotherapy with birch pollen.

artículo científico publicado en 2013

Long-lived Th2 clones specific for seasonal and perennial allergens can be detected in blood and skin by their TCR-hypervariable regions

scientific article published on 01 February 1998

Modulation of allergen-specific T-lymphocyte function by virus-like particles decorated with HLA class II molecules

artículo científico publicado en 2009

Modulation of the allergic immune response in BALB/c mice by subcutaneous injection of high doses of the dominant T cell epitope from the major birch pollen allergen Bet v 1.

artículo científico publicado en 1997

Molecular and functional analysis of the antigen receptor of Art v 1-specific helper T lymphocytes.

artículo científico publicado en 2007

Monitoring the epitope recognition profiles of IgE, IgG 1 , and IgG 4 during birch pollen immunotherapy

scientific article published on 10 December 2015

Mutational analysis of amino acid positions crucial for IgE-binding epitopes of the major apple (Malus domestica) allergen, Mal d 1.

artículo científico publicado en 2005

NSG mice humanized with allergen-specific T-cell lines as in vivo model of respiratory allergy

scientific article published on 07 March 2020

Natural and recombinant molecules of the cherry allergen Pru av 2 show diverse structural and B cell characteristics but similar T cell reactivity.

artículo científico publicado en 2006

Natural self-assembly of allergen-S-layer fusion proteins is no prerequisite for reduced allergenicity and T cell stimulatory capacity.

artículo científico publicado en 2009

Naturally processed T cell-activating peptides of the major birch pollen allergen.

artículo científico publicado en 2010

Neutrophils promote T-cell-mediated inflammation in allergy

scientific article published on 19 December 2018

Nitration of the pollen allergen bet v 1.0101 enhances the presentation of bet v 1-derived peptides by HLA-DR on human dendritic cells

artículo científico publicado en 2012

Oligodeoxynucleotides containing CpG motifs induce IL-12, IL-18 and IFN-gamma production in cells from allergic individuals and inhibit IgE synthesis in vitro

artículo científico publicado en 1999

Oligodeoxynucleotides containing CpG motifs induce low levels of TNF-alpha in human B lymphocytes: possible adjuvants for Th1 responses.

artículo científico publicado en 2001

Oligodeoxynucleotides containing CpG motifs modulate the allergic TH2 response of BALB/c mice to Bet v 1, the major birch pollen allergen.

artículo científico publicado en 1999

Oral exposure to Mal d 1 affects the immune response in patients with birch pollen allergy

artículo científico publicado en 2012

Peptide mimotopes displayed by phage inhibit antibody binding to bet v 1, the major birch pollen allergen, and induce specific IgG response in mice.

artículo científico publicado en 1998

Persistent pruritus after hydroxyethyl starch infusion therapy: a result of long-term storage in cutaneous nerves

scientific article published on 01 April 1997

Prevention of birch pollen-related food allergy by mucosal treatment with multi-allergen-chimers in mice

artículo científico publicado en 2012

Profiling of human CD4+ T-cell subsets identifies the TH2-specific noncoding RNA GATA3-AS1.

artículo científico publicado en 2013

Protection against invasive amebiasis by a single monoclonal antibody directed against a lipophosphoglycan antigen localized on the surface of Entamoeba histolytica

artículo científico publicado en 1997

Protein unfolding strongly modulates the allergenicity and immunogenicity of Pru p 3, the major peach allergen

Proteomic profiling of the weed feverfew, a neglected pollen allergen source.

artículo científico

Pru p 3, the nonspecific lipid transfer protein from peach, dominates the immune response to its homolog in hazelnut

artículo científico publicado en 2011

Recombinant Mal d 1 facilitates sublingual challenge tests of birch pollen-allergic patients with apple allergy.

artículo científico publicado en 2015

Recombinant Mal d 1 is a reliable diagnostic tool for birch pollen allergen-associated apple allergy

artículo científico publicado en 2013

Recommendations for the allergy management in the primary care.

artículo científico

Regulation of cytokine production in human peripheral blood mononuclear cells and allergen-specific th cell clones by 1alpha,25-dihydroxyvitamin D3.

artículo científico publicado en 2002

Reshaping the Bet v 1 fold modulates T(H) polarization.

artículo científico publicado en 2011

Risk and safety requirements for diagnostic and therapeutic procedures in allergology: World Allergy Organization Statement

artículo científico publicado en 2016

Sclerostin serum levels correlate positively with bone mineral density and microarchitecture in haemodialysis patients

artículo científico publicado en 2011

Similar Allergenicity to Different Artemisia Species Is a Consequence of Highly Cross-Reactive Art v 1-Like Molecules

artículo científico publicado en 2019

Structural and immunological characterization of the N-glycans from the major yellow jacket allergen Ves v 2: the N-glycan structures are needed for the human antibody recognition.

artículo científico publicado en 2009

Sublingual immunotherapy induces IL-10-producing T regulatory cells, allergen-specific T-cell tolerance, and immune deviation

artículo científico publicado en 2007

Sublingual immunotherapy with recombinant Mal d 1 downregulates the allergen-specific Th2 response

scientific article published on 10 April 2019

Successful sublingual immunotherapy with birch pollen has limited effects on concomitant food allergy to apple and the immune response to the Bet v 1 homolog Mal d 1.

artículo científico publicado en 2007

Suppression of antigen-specific T- and B-cell responses by intranasal or oral administration of recombinant bet v 1, the major birch pollen allergen, in a murine model of type I allergy

artículo científico publicado en 1999

Surface LAMP-2 Is an Endocytic Receptor That Diverts Antigen Internalized by Human Dendritic Cells into Highly Immunogenic Exosomes.

artículo científico publicado en 2017

Systemic immunological changes induced by administration of grass pollen allergens via the oral mucosa during sublingual immunotherapy

artículo científico publicado en 1999

T Cell Epitope-Containing Domains of Ragweed Amb a 1 and Mugwort Art v 6 Modulate Immunologic Responses in Humans and Mice

artículo científico publicado en 2017

T cell responses during allergen-specific immunotherapy of Type I allergy.

artículo científico publicado en 2008

T lymphocytes and food allergy

artículo científico publicado en 2004

T-cell epitopes of food allergens.

artículo científico publicado en 2006

T-cell-derived cytokines enhance the antigen-presenting capacity of human neutrophils

scientific article published on 06 August 2019

TGF-beta1 impairs homocysteine metabolism in human renal cells: possible implications for transplantation

artículo científico publicado en 2003

Tackling Bet v 1 and associated food allergies with a single hybrid protein.

artículo científico publicado en 2016

Targeting antigens to murine and human M-cells with Aleuria aurantia lectin-functionalized microparticles.

artículo científico publicado en 2005

Targeting the cysteine-stabilized fold of Art v 1 for immunotherapy of Artemisia pollen allergy

artículo científico publicado en 2010

The Effect of Birch Pollen Immunotherapy on Apple and rMal d 1 Challenges in Adults with Apple Allergy

artículo científico publicado en 2020

The IgE-reactive autoantigen Hom s 2 induces damage of respiratory epithelial cells and keratinocytes via induction of IFN-gamma.

artículo científico publicado en 2007

The T cell response to Art v 1, the major mugwort pollen allergen, is dominated by one epitope.

artículo científico publicado en 2002

The T-cell response to Amb a 1 is characterized by 3 dominant epitopes and multiple MHC restriction elements

artículo científico publicado en 2010

The alpha and beta subchain of Amb a 1, the major ragweed-pollen allergen show divergent reactivity at the IgE and T-cell level.

artículo científico publicado en 2009

The diversity of Bet v 1–specific IgG 4 antibodies remains mostly constant during the course of birch pollen immunotherapy

scientific article published on 02 July 2015

The immunological relationship of epitopes on major tree pollen allergens.

artículo científico publicado en 1991

The impact of nitration on the structure and immunogenicity of the major birch pollen allergen Bet v 1.0101.

artículo científico publicado en 2014

The impact of pollen-related food allergens on pollen allergy.

artículo científico publicado en 2007

The quantity and quality of α-gal-specific antibodies differ in individuals with and without delayed red meat allergy

artículo científico publicado en 2016

The role of IgG1 and IgG4 as dominant IgE-blocking antibodies shifts during allergen immunotherapy

artículo científico publicado en 2023

The soluble isoform of human FcɛRI is an endogenous inhibitor of IgE-mediated mast cell responses

artículo científico publicado en 2018

Toll-like receptor ligands as adjuvants in allergy vaccines

Toll-like receptors as targets for enhancing the efficacy of immunotherapy

artículo científico publicado en 2009

Tropomyosins in mosquito and house dust mite cross-react at the humoral and cellular level

scientific article published on 14 August 2018

Two Distinct Conformations in Bet v 2 Determine Its Proteolytic Resistance to Cathepsin S.

artículo científico publicado en 2017

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artículo científico

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