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A Human REPIN1 Gene Variant: Genetic Risk Factor for the Development of Nonalcoholic Fatty Liver Disease

artículo científico publicado en 2020

A novel thermoregulatory role for PDE10A in mouse and human adipocytes

artículo científico publicado en 2016

ADCY5 gene expression in adipose tissue is related to obesity in men and mice

artículo científico publicado en 2015

ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype

artículo científico publicado en 2017

Ablation of kallikrein 7 (KLK7) in adipose tissue ameliorates metabolic consequences of high fat diet-induced obesity by counteracting adipose tissue inflammation in vivo

artículo científico publicado en 2017

Access to gram scale amounts of functional globular adiponectin from E. coli inclusion bodies by alkaline-shock solubilization

artículo científico publicado en 2010

Accumulation of distinct persistent organic pollutants is associated with adipose tissue inflammation

scientific article published on 23 September 2020

Activated Ask1-MKK4-p38MAPK/JNK Stress Signaling Pathway in Human Omental Fat Tissue May Link Macrophage Infiltration to Whole-Body Insulin Sensitivity.

artículo científico publicado en 2009

Activated Ask1-MKK4-p38MAPK/JNK stress signaling pathway in human omental fat tissue may link macrophage infiltration to whole-body Insulin sensitivity

artículo científico publicado en 2009

Adipocyte dysfunction, inflammation and metabolic syndrome

artículo científico publicado en 2014

Adipocyte size threshold matters: link with risk of type 2 diabetes and improved insulin resistance after gastric bypass

artículo científico publicado en 2014

Adipose Tissue is a Potential Source of Hyperandrogenism in Obese Female Rats

artículo científico publicado en 2018

Adipose dipeptidyl peptidase-4 and obesity: correlation with insulin resistance and depot-specific release from adipose tissue in vivo and in vitro

scientific article published on 15 October 2013

Adipose tissue expression and genetic variants of the bone morphogenetic protein receptor 1A gene (BMPR1A) are associated with human obesity

artículo científico publicado en 2009

Adipose triglyceride lipase gene expression in human visceral obesity

artículo científico publicado en 2007

Alleles of diabetes-resistant BN rats contribute to insulin-dependent type 1 diabetes mellitus

artículo científico publicado en 2003

Alleles on rat chromosome 4 (D4Got41-Fabp1/Tacr1) regulate subphenotypes of obesity

artículo científico publicado en 2005

Altered Autophagy in Human Adipose Tissues in Obesity

artículo científico publicado en 2010

Altered autophagy in human adipose tissues in obesity

artículo científico publicado en 2010

Aminoguanidine downregulates expression of cytokine-induced Fas and inducible nitric oxide synthase but not cytokine-enhanced surface antigens of rat islet cells

artículo científico publicado en 2003

Antioxidants prevent health-promoting effects of physical exercise in humans

artículo científico publicado en 2009

Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance

artículo científico publicado en 2015

Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth

artículo científico publicado en 2008

Autophagy determines efficiency of liver-directed gene therapy with adeno-associated viral vectors

artículo científico publicado en 2017

Autophagy in adipose tissue of patients with obesity and type 2 diabetes

artículo científico publicado en 2015

Bone morphogenetic protein 2 (BMP2) may contribute to partition of energy storage into visceral and subcutaneous fat depots

artículo científico publicado en 2016

Brown adipose tissue (BAT) specific vaspin expression is increased after obesogenic diets and cold exposure and linked to acute changes in DNA-methylation

artículo científico publicado en 2017

C57BL/6JRj mice are protected against diet induced obesity (DIO).

artículo científico publicado en 2011

CD14 triggers autoimmune Type 1 diabetes in the NOD mouse ⬇️

artículo científico publicado el 12 de noviembre de 2003

COL6A3 expression in adipocytes associates with insulin resistance and depends on PPARγ and adipocyte size

artículo científico publicado en 2014

COMP-Ang-1 Improves Glucose Uptake in db/db Mice with Type 2 Diabetes

scientific article published on 06 April 2020

COMP-angiopoietin-1 recovers molecular biomarkers of neuropathy and improves vascularisation in sciatic nerve of ob/ob mice

artículo científico publicado en 2012

Central vaspin administration acutely reduces food intake and has sustained blood glucose-lowering effects

artículo científico publicado en 2011

Circulating adipocyte fatty acid binding protein is increased in chronic and acute renal dysfunction

artículo científico publicado en 2014

Circulating adipocyte fatty acid-binding protein induces insulin resistance in mice in vivo

artículo científico publicado en 2015

Circulating adiponectin and expression of adiponectin receptors in human skeletal muscle: associations with metabolic parameters and insulin resistance and regulation by physical training

artículo científico publicado en 2006

Circulating cell adhesion molecules in metabolically healthy obesity

artículo científico publicado en 2020

Circulating progranulin but not renal progranulin expression is increased in renal dysfunction

artículo científico publicado en 2015

Congenic mapping of type 1 diabetes--protective gene(s) in an interval of 4 Mb on rat chromosome 6q32

artículo científico publicado en 2004

Defective peripheral nerve development is linked to abnormal architecture and metabolic activity of adipose tissue in Nscl-2 mutant mice

artículo científico publicado en 2009

Deletion of CD73 promotes dyslipidemia and intramyocellular lipid accumulation in muscle of mice ⬇️

artículo científico publicado el 11 de febrero de 2013

Di-(2-Ethylhexyl)-Phthalate (DEHP) Causes Impaired Adipocyte Function and Alters Serum Metabolites

artículo científico publicado en 2015

Diabetes per se and metabolic state influence gene expression in tissue-dependent manner of BB/OK rats

artículo científico publicado en 2005

Dissociation Between Brown Adipose Tissue 18F-FDG Uptake and Thermogenesis in Uncoupling Protein 1-Deficient Mice

artículo científico publicado en 2017

Distinct abdominal and gluteal adipose tissue transcriptome signatures are altered by exercise training in African women with obesity

artículo científico publicado en 2020

Dysregulation of the peripheral and adipose tissue endocannabinoid system in human abdominal obesity

artículo científico publicado en 2006

Effect of a 4 week physical training program on plasma concentrations of inflammatory markers in patients with abnormal glucose tolerance

artículo científico publicado en 2006

Effect of genetic variation in the human fatty acid synthase gene (FASN) on obesity and fat depot-specific mRNA expression

artículo científico publicado en 2009

Effects of Weight Loss on Glutathione Peroxidase 3 Serum Concentrations and Adipose Tissue Expression in Human Obesity

Effects of exercise on ACE2

scientific article published on 17 September 2020

Effects of genetic variation in the human retinol binding protein-4 gene (RBP4) on insulin resistance and fat depot-specific mRNA expression

artículo científico publicado en 2007

Effects of isoflurane anesthesia on F-waves in the sciatic nerve of the adult rat.

artículo científico publicado en 2014

Effects of weight loss and exercise on apelin serum concentrations and adipose tissue expression in human obesity

artículo científico publicado en 2013

Effects of weight loss and exercise on chemerin serum concentrations and adipose tissue expression in human obesity

artículo científico publicado en 2011

Elevated autophagy gene expression in adipose tissue of obese humans: A potential non-cell-cycle-dependent function of E2F1.

artículo científico publicado en 2015

Ex vivo gene transfer of viral interleukin-10 to BB rat islets: no protection after transplantation to diabetic BB rats

scientific article published on July 2007

Extended longevity and insulin signaling in adipose tissue

artículo científico publicado en 2005

Extensive weight loss reveals distinct gene expression changes in human subcutaneous and visceral adipose tissue

artículo científico publicado en 2015

FSTL3 is increased in renal dysfunction

artículo científico publicado en 2017

Fas and FasL expression in human adipose tissue is related to obesity, insulin resistance, and type 2 diabetes

artículo científico publicado en 2013

Fat depot-specific expression of HOXC9 and HOXC10 may contribute to adverse fat distribution and related metabolic traits

artículo científico publicado en 2015

Fat depot-specific mRNA expression of novel loci associated with waist-hip ratio

artículo científico publicado en 2013

Fatty acid synthase gene expression in human adipose tissue: association with obesity and type 2 diabetes

artículo científico publicado en 2007

Free fatty acids sensitize dendritic cells to amplify TH1/TH17-immune responses

artículo científico publicado en 2016

Functional changes of the gastric bypass microbiota reactivate thermogenic adipose tissue and systemic glucose control via intestinal FXR-TGR5 crosstalk in diet-induced obesity

artículo científico publicado en 2022

Functional relevance of genes implicated by obesity genome-wide association study signals for human adipocyte biology

artículo científico publicado en 2012

Gene expression of PPARgamma and PGC-1alpha in human omental and subcutaneous adipose tissues is related to insulin resistance markers and mediates beneficial effects of physical training

artículo científico publicado en 2009

Gene expression of adiponectin receptors in human visceral and subcutaneous adipose tissue is related to insulin resistance and metabolic parameters and is altered in response to physical training

artículo científico publicado en 2007

Gene expression profiling in adipose tissue of Sprague Dawley rats identifies olfactory receptor 984 as a potential obesity treatment target

article

Gene expression profiling supports the role of Repin1 in the pathophysiology of metabolic syndrome

artículo científico publicado en 2011

Genes on rat chromosomes 3, 5, 10, and 16 are linked with facets of metabolic syndrome.

artículo científico publicado en 2009

Genetic and biochemical evidence for a functional role of BACE1 in the regulation of insulin mRNA expression

artículo científico publicado en 2013

Genetic and evolutionary analyses of the human bone morphogenetic protein receptor 2 (BMPR2) in the pathophysiology of obesity

artículo científico publicado en 2011

Genetic variation in the multifunctional transcription factor Yy1 and type 1 diabetes mellitus in the BB rat.

artículo científico publicado en 2004

Genetic variation in the visfatin gene (PBEF1) and its relation to glucose metabolism and fat-depot-specific messenger ribonucleic acid expression in humans

artículo científico publicado en 2006

Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the regulation of circulating serum chemerin

artículo científico publicado en 2014

Glucose concentration and AMP-dependent kinase activation regulate expression of insulin receptor family members in rat islets and INS-1E beta cells

artículo científico publicado en 2005

Glucose regulates expression of the nerve growth factor (NGF) receptors TrkA and p75NTR in rat islets and INS-1E beta-cells

artículo científico publicado en 2006

HLA Class II Allele Analyses Implicate Common Genetic Components in Type 1 and Non-Insulin-Treated Type 2 Diabetes

scientific article published on 01 March 2020

Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis.

artículo científico publicado en 2016

Hedgehog signalling in myeloid cells impacts on body weight, adipose tissue inflammation and glucose metabolism

artículo científico publicado en 2017

High metabolic in vivo stability and bioavailability of a palmitoylated ghrelin receptor ligand assessed by mass spectrometry

artículo científico publicado en 2014

High‐fat diet protects BB/OK rats from developing type 1 diabetes ⬇️

artículo científico publicado el 1 de septiembre de 2011

Hypoxia-inducible factor 3A gene expression and methylation in adipose tissue is related to adipose tissue dysfunction

artículo científico publicado en 2016

Iddm1 and Iddm2 Homozygous WOK.4BB Rats Develop Lymphopenia, but no Hyperglycemia like the BB/OK Rats ⬇️

artículo científico publicado el 3 de marzo de 2011

Identification of a regulatory pathway inhibiting adipogenesis via RSPO2

artículo científico publicado en 2022

Identification of adipokine clusters related to parameters of fat mass, insulin sensitivity and inflammation

artículo científico publicado en 2014

Identification of genetic loci associated with different responses to high-fat diet-induced obesity in C57BL/6N and C57BL/6J substrains

artículo científico publicado en 2014

Increased Ifi202b/IFI16 expression stimulates adipogenesis in mice and humans.

artículo científico publicado en 2018

Increased autophagy in peripheral nerves may protect Wistar Ottawa Karlsburg W rats against neuropathy

artículo científico publicado en 2013

Increased circulating chemerin in patients with advanced carotid stenosis

artículo científico publicado en 2018

Insulin up-regulates natriuretic peptide clearance receptor expression in the subcutaneous fat depot in obese subjects: a missing link between CVD risk and obesity?

artículo científico publicado en 2012

Insulin-Like Peptide 5 Interacts with Sex Hormones and Metabolic Parameters in a Gender and Adiposity Dependent Manner in Humans

artículo científico publicado en 2016

Insulin-sensitive obesity

artículo científico publicado en 2010

Inverse relationship between obesity and FTO gene expression in visceral adipose tissue in humans

artículo científico publicado en 2008

Is subcutaneous adipose tissue expansion in people living with lipedema healthier and reflected by circulating parameters?

artículo científico publicado en 2022

Is there an autoimmune process in bone? Gene expression studies in diabetic and nondiabetic BB rats as well as BB rat-related and -unrelated rat strains

artículo científico publicado en 2005

Is there relatedness between maternal lines of Type 1 diabetic patients?

scientific article published on 01 March 2003

Leptin Within the Subphysiological to Physiological Range Dose Dependently Improves Male Reproductive Function in an Obesity Mouse Model

artículo científico publicado en 2016

Leptin decreases circulating inflammatory IL-6 and MCP-1 in mice

scientific article published on 29 November 2018

Leptin dose-dependently decreases atherosclerosis by attenuation of hypercholesterolemia and induction of adiponectin

artículo científico publicado en 2015

Leptin restores markers of female fertility in lipodystrophy

scientific article published on 23 July 2018

Leptin-deficient (ob/ob) mouse ovaries show fatty degeneration, enhanced apoptosis and decreased expression of steroidogenic acute regulatory enzyme ⬇️

artículo científico publicado el 15 de noviembre de 2011

Linagliptin Improves Insulin Sensitivity and Hepatic Steatosis in Diet-Induced Obesity ⬇️

artículo científico publicado el 22 de junio de 2012

Liver-restricted Repin1 deficiency improves whole-body insulin sensitivity, alters lipid metabolism, and causes secondary changes in adipose tissue in mice

artículo científico publicado en 2014

Liver-specific Repin1 deficiency impairs transient hepatic steatosis in liver regeneration

artículo científico publicado en 2018

Local proliferation of macrophages in adipose tissue during obesity-induced inflammation

artículo científico publicado en 2013

Loss of function of Ifi202b by a microdeletion on chromosome 1 of C57BL/6J mice suppresses 11β-hydroxysteroid dehydrogenase type 1 expression and development of obesity

artículo científico publicado en 2012

Macrophage infiltration into omental versus subcutaneous fat across different populations: effect of regional adiposity and the comorbidities of obesity

artículo científico publicado en 2007

Metabolic effects of genetic variation in the human REPIN1 gene

artículo científico publicado en 2018

MicroRNA expression in human omental and subcutaneous adipose tissue

artículo científico publicado en 2009

NPY1R-targeted peptide-mediated delivery of a dual PPARα/γ agonist to adipocytes enhances adipogenesis and prevents diabetes progression

scientific article published on 16 November 2019

Neuropeptide Y impairs insulin-stimulated translocation of glucose transporter 4 in 3T3-L1 adipocytes through the Y1 receptor ⬇️

artículo científico publicado el 27 de julio de 2011

Nicotinamide Nucleotide Transhydrogenase (Nnt) is Related to Obesity in Mice

artículo científico publicado en 2020

Nicotinamide nucleotide transhydrogenase mRNA expression is related to human obesity

artículo científico publicado en 2013

Novel genes on rat chromosome 10 are linked to body fat mass, preadipocyte number and adipocyte size

artículo científico publicado en 2016

PACAP up-regulates the expression of apolipoprotein D in 3T3-L1 adipocytes. DRG/3T3-L1 co-cultures study ⬇️

artículo científico publicado el 13 de noviembre de 2010

PPP2R5C Couples Hepatic Glucose and Lipid Homeostasis

artículo científico publicado en 2015

Phenotypic and genetic analyses of subcongenic BB.SHR rat lines shorten the region on chromosome 4 bearing gene(s) for underlying facets of metabolic syndrome

artículo científico publicado en 2004

Plasma visfatin concentrations and fat depot-specific mRNA expression in humans

artículo científico publicado en 2005

Prenatal notch1 receptor blockade by protein delta homolog 1 (DLK1) modulates adipocyte size in vivo

artículo científico publicado en 2015

Prepubertal onset of obesity negatively impacts on testicular steroidogenesis in rats

artículo científico

Pro-Neurotensin depends on renal function and is related to all-cause mortality in chronic kidney disease

artículo científico publicado en 2020

Rational design of dual peptides targeting ghrelin and Y2 receptors to regulate food intake and body weight

artículo científico publicado en 2015

Repin1 deficiency improves insulin sensitivity and glucose metabolism in db/db mice by reducing adipose tissue mass and inflammation

artículo científico publicado en 2016

Repin1 deficiency in adipose tissue improves whole-body insulin sensitivity, and lipid metabolism

artículo científico publicado en 2017

Repin1 deficiency in liver tissue alleviates NAFLD progression in mice

artículo científico publicado en 2018

Repin1 maybe involved in the regulation of cell size and glucose transport in adipocytes

scientific journal article

Replication Initiator 1 in Adipose Tissue Function and Human Obesity

artículo científico publicado el 1 de enero de 2013

Role of Kallikrein 7 in Body Weight and Fat Mass Regulation

artículo científico publicado en 2021

Role of genetic variation in the cannabinoid type 1 receptor gene (CNR1) in the pathophysiology of human obesity

artículo científico publicado en 2010

Serum progranulin concentrations may be associated with macrophage infiltration into omental adipose tissue

scientific article published on 03 December 2008

Serum retinol-binding protein is more highly expressed in visceral than in subcutaneous adipose tissue and is a marker of intra-abdominal fat mass

artículo científico publicado en 2007

Serum vaspin concentrations in human obesity and type 2 diabetes

artículo científico publicado en 2007

TCF7L2 gene expression in human visceral and subcutaneous adipose tissue is differentially regulated but not associated with type 2 diabetes mellitus

artículo científico publicado en 2008

TSH compensates thyroid-specific IGF-I receptor knockout and causes papillary thyroid hyperplasia

artículo científico publicado en 2011

Tamoxifen affects glucose and lipid metabolism parameters, causes browning of subcutaneous adipose tissue and transient body composition changes in C57BL/6NTac mice

artículo científico publicado en 2015

Tamoxifen treatment causes early hepatic insulin resistance

scientific article published on 06 January 2020

Telomere length differences between subcutaneous and visceral adipose tissue in humans

artículo científico publicado en 2015

The Effect of Wolffia globosa Mankai, a Green Aquatic Plant, on Postprandial Glycemic Response: A Randomized Crossover Controlled Trial

scientific article published on 10 May 2019

The Effects of Thyroid Hormones on Gene Expression of Acyl-Coenzyme A Thioesterases in Adipose Tissue and Liver of Mice

artículo científico publicado en 2015

The Fabp4-Cre-Model is Insufficient to Study Hoxc9 Function in Adipose Tissue

artículo científico publicado en 2020

The Obesity-Susceptibility Gene TMEM18 Promotes Adipogenesis through Activation of PPARG

artículo científico publicado en 2020

The Role of Iron and Nerve Inflammation in Diabetes Mellitus Type 2-Induced Peripheral Neuropathy

artículo científico publicado en 2019

The SGLT2 inhibitor empagliflozin improves insulin sensitivity in db/db mice both as monotherapy and in combination with linagliptin

artículo científico publicado en 2015

The brown fat-secreted adipokine neuregulin 4 is decreased in human and murine chronic kidney disease

scientific article published on 01 August 2019

The effect of high-polyphenol Mediterranean diet on visceral adiposity: the DIRECT PLUS randomized controlled trial

artículo científico publicado en 2022

The novel adipokine/hepatokine fetuin B in severe human and murine diabetic kidney disease

artículo científico publicado en 2017

The polygenetically inherited metabolic syndrome of WOKW rats is associated with insulin resistance and altered gene expression in adipose tissue

artículo científico publicado en 2006

The polygenetically inherited metabolic syndrome of male WOKW rats is associated with enhanced autophagy in adipose tissue

artículo científico publicado en 2013

The role of dietary non-heme iron load and peripheral nerve inflammation in the development of peripheral neuropathy (PN) in obese non-diabetic leptin-deficient ob/ob mice

artículo científico publicado en 2019

The role of nerve inflammation and exogenous iron load in experimental peripheral diabetic neuropathy (PDN).

artículo científico publicado en 2015

Thyroid hormone status defines brown adipose tissue activity and browning of white adipose tissues in mice

artículo científico publicado en 2016

Tick-tock hedgehog-mutual crosstalk with liver circadian clock promotes liver steatosis

artículo científico publicado en 2019

Transplantation of adipose tissue protects BB/OK rats from type 1 diabetes development ⬇️

artículo científico publicado el 26 de enero de 2011

Triplet repeat in the Repin1 3'-untranslated region on rat chromosome 4 correlates with facets of the metabolic syndrome

scientific article published on 01 July 2007

Two patterns of adipokine and other biomarker dynamics in a long-term weight loss intervention

artículo científico publicado en 2011

Up-regulated autophagy: as a protective factor in adipose tissue of WOKW rats with metabolic syndrome

artículo científico publicado en 2018

Vaspin gene expression in human adipose tissue: association with obesity and type 2 diabetes

artículo científico publicado en 2005

Vaspin inhibits kallikrein 7 by serpin mechanism

artículo científico publicado en 2013

Vaspin serum concentrations in patients with carotid stenosis

artículo científico publicado en 2008

Visfatin is a positive regulator of MCP-1 in human adipocytes in vitro and in mice in vivo

artículo científico publicado en 2009

Visfatin: gene expression in isolated adipocytes and sequence analysis in obese WOKW rats compared with lean control rats

artículo científico publicado en 2005

WISP1 is a novel adipokine linked to inflammation in obesity

artículo científico publicado en 2014

[The biology of visceral fat]

artículo científico publicado en 2007

microRNA-379 couples glucocorticoid hormones to dysfunctional lipid homeostasis

artículo científico publicado en 2014

p8 deficiency leads to elevated pancreatic beta cell mass but does not contribute to insulin resistance in mice fed with high-fat diet

scientific article published on 24 July 2018

40 EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004 ⬇️

artículo

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