Lista de obras - Mark Kester - Dominio Público Uruguay

A Cholecystokinin B Receptor-Specific DNA Aptamer for Targeting Pancreatic Ductal Adenocarcinoma

artículo científico publicado en 2016

A novel biologically active acid stable liposomal formulation of docosahexaenoic acid in human breast cancer cell lines

artículo científico publicado en 2016

AP-1 binding transcriptionally regulates human neutral ceramidase

artículo científico publicado en 2011

Altered sphingolipid metabolism in patients with metastatic pancreatic cancer

artículo científico publicado en 2013

Autophagosomal membrane serves as platform for intracellular death-inducing signaling complex (iDISC)-mediated caspase-8 activation and apoptosis

artículo científico publicado en 2012

Bif-1 regulates Atg9 trafficking by mediating the fission of Golgi membranes during autophagy

artículo científico publicado en 2011

C(6)-Ceramide-Coated Catheters Promote Re-Endothelialization of Stretch-Injured Arteries

artículo científico publicado en 2008

C6-ceramide nanoliposomes target the Warburg effect in chronic lymphocytic leukemia

artículo científico publicado en 2013

Calcium phosphate nanocomposite particles for in vitro imaging and encapsulated chemotherapeutic drug delivery to cancer cells

artículo científico publicado en 2008

Calcium phosphate-based composite nanoparticles in bioimaging and therapeutic delivery applications

artículo científico

Calcium phosphosilicate nanoparticles for imaging and photodynamic therapy of cancer

artículo científico

Ceramide 1-phosphate mediates endothelial cell invasion via the annexin a2-p11 heterotetrameric protein complex

artículo científico publicado en 2013

Ceramide kinase regulates TNFα-stimulated NADPH oxidase activity and eicosanoid biosynthesis in neuroblastoma cells

artículo científico publicado en 2011

Ceramide modulates HERG potassium channel gating by translocation into lipid rafts

artículo científico publicado en 2010

Ceramide nanoliposomes as a MLKL-dependent, necroptosis-inducing, chemotherapeutic reagent in ovarian cancer

artículo científico publicado en 2017

Ceramide recruits and activates protein kinase C zeta (PKC zeta) within structured membrane microdomains

scientific journal article

Ceramide--antiestrogen nanoliposomal combinations--novel impact of hormonal therapy in hormone-insensitive breast cancer

artículo científico publicado en 2012

Ceramide-based therapeutics for the treatment of cancer

artículo científico publicado el 1 de noviembre de 2011

Ceramide-induced inhibition of Akt is mediated through protein kinase Czeta: implications for growth arrest

artículo científico publicado en 2002

Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia

artículo científico publicado en 2016

Characterization of insulin signaling in rat retina in vivo and ex vivo

artículo científico publicado en 2003

Circulating sphingolipid biomarkers in models of type 1 diabetes

artículo científico publicado en 2010

Clinical experience using a minimally invasive surgical approach for total knee arthroplasty: early results of a prospective randomized study compared to a standard approach

artículo científico publicado en 2007

Clinical, objective, and functional outcomes of manipulation under anesthesia to treat knee stiffness following total knee arthroplasty

artículo científico publicado en 2013

Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer ⬇️

artículo científico publicado el 1 de octubre de 2011

Combining nanoliposomal ceramide with sorafenib synergistically inhibits melanoma and breast cancer cell survival to decrease tumor development

artículo científico publicado en 2008

Delivery of PAR-4 plasmid in vivo via nanoliposomes sensitizes colon tumor cells subcutaneously implanted into nude mice to 5-FU.

artículo científico publicado en 2009

Deregulated Akt3 activity promotes development of malignant melanoma

artículo científico publicado en 2004

Development and use of ceramide nanoliposomes in cancer.

artículo científico publicado en 2012

Diabetes alters sphingolipid metabolism in the retina: a potential mechanism of cell death in diabetic retinopathy

artículo científico publicado en 2006

Diabetes diminishes phosphatidic acid in the retina: a putative mediator for reduced mTOR signaling and increased neuronal cell death

artículo científico publicado en 2012

Diabetic retinopathy: seeing beyond glucose-induced microvascular disease.

artículo científico publicado en 2006

Dynamics of ceramide generation and metabolism in response to fenretinide--Diversity within and among leukemia

artículo científico publicado en 2015

Dysregulation of sphingolipid metabolism in cancer ⬇️

artículo científico publicado el 15 de enero de 2011

Effect of IL-1beta on survival and energy metabolism of R28 and RGC-5 retinal neurons

artículo científico publicado en 2008

Effective encapsulation and biological activity of phosphorylated chemotherapeutics in calcium phosphosilicate nanoparticles for the treatment of pancreatic cancer

artículo científico publicado en 2017

Emerging technologies in arthroplasty: additive manufacturing

artículo científico publicado en 2014

Encapsulation of organic molecules in calcium phosphate nanocomposite particles for intracellular imaging and drug delivery

artículo científico publicado en 2008

Engraftment of Human Primary Acute Myeloid Leukemia Defined by Integrated Genetic Profiling in NOD/SCID/IL2rγnull Mice for Preclinical Ceramide-Based Therapeutic Evaluation.

artículo científico publicado en 2014

Ether-linked diglycerides inhibit vascular smooth muscle cell growth via decreased MAPK and PI3K/Akt signaling

artículo científico publicado en 2008

Exogenous ceramide-1-phosphate reduces lipopolysaccharide (LPS)-mediated cytokine expression

artículo científico publicado en 2011

Formation and role of exosomes in cancer

artículo científico publicado en 2014

Growth of human pancreatic cancer is inhibited by down-regulation of gastrin gene expression

scientific article published on July 2009

Inhibition of NADPH oxidase by glucosylceramide confers chemoresistance ⬇️

artículo científico publicado el 1 de diciembre de 2010

Inhibition of corneal inflammation by liposomal delivery of short-chain, C-6 ceramide

artículo científico publicado en 2008

Innovations in knee arthroplasty: three-dimensional modeling and analytical technology (SOMA).

artículo científico publicado en 2014

Liposomal Delivery of Diacylglycerol Lipase-Beta Inhibitors to Macrophages Dramatically Enhances Selectivity and Efficacy in Vivo

artículo científico publicado en 2017

Liposomal delivery enhances short-chain ceramide-induced apoptosis of breast cancer cells

artículo científico publicado en 2003

Long-term outcomes of MUA for stiffness in primary TKA.

artículo científico

Lysosomal degradation of CD44 mediates ceramide nanoliposome-induced anoikis and diminished extravasation in metastatic carcinoma cells

artículo científico publicado en 2015

Minimally invasive total knee arthroplasty.

artículo científico publicado en 2004

Modification of sphingolipid metabolism by tamoxifen and N-desmethyltamoxifen in acute myelogenous leukemia--Impact on enzyme activity and response to cytotoxics

artículo científico publicado en 2015

Nanoliposomal minocycline for ocular drug delivery

artículo científico publicado en 2012

Nanoliposomal short-chain ceramide inhibits agonist-dependent translocation of neurotensin receptor 1 to structured membrane microdomains in breast cancer cells

artículo científico publicado en 2009

Nanoliposome C6-Ceramide Increases the Anti-tumor Immune Response and Slows Growth of Liver Tumors in Mice

artículo científico publicado en 2018

Nanoparticulate Alternatives for Drug Delivery ⬇️

artículo científico publicado el 28 de septiembre de 2010

Neurotensin receptor-1 inducible palmitoylation is required for efficient receptor-mediated mitogenic-signaling within structured membrane microdomains

artículo científico publicado en 2011

Novel Sphingolipid-Based Cancer Therapeutics in the Personalized Medicine Era

artículo científico publicado en 2018

Paralemmin interacts with D3 dopamine receptors: implications for membrane localization and cAMP signaling

artículo científico publicado en 2006

Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway

artículo científico publicado en 2010

Preclinical development of a C6-ceramide NanoLiposome, a novel sphingolipid therapeutic

artículo científico

Predicting the effect of tray malalignment on risk for bone damage and implant subsidence after total knee arthroplasty

artículo científico publicado en 2010

Propagation of Undifferentiated Human Embryonic Stem Cells with Nano-Liposomal Ceramide

artículo científico publicado en 2009

Rapid distribution of liposomal short-chain ceramide in vitro and in vivo

artículo científico publicado en 2008

Regulatory role of sphingomyelin metabolites in hypoxia-induced vascular smooth muscle cell proliferation

artículo científico publicado en 2002

Role of P-glycoprotein inhibitors in ceramide-based therapeutics for treatment of cancer

artículo científico publicado en 2017

Rotational constraint of posterior-stabilized total knee prostheses

artículo científico publicado en 2008

SKI-178: A Multitargeted Inhibitor of Sphingosine Kinase and Microtubule Dynamics Demonstrating Therapeutic Efficacy in Acute Myeloid Leukemia Models

artículo científico publicado en 2017

STAT3 mediates C6-ceramide-induced cell death in chronic lymphocytic leukemia

Short-chain ceramides depress integrin cell surface expression and function in colorectal cancer cells

artículo científico publicado en 2016

Single radius total knee arthroplasty: PCL sacrifice without substitution yields excellent outcomes minimum 8-year follow-up.

artículo científico publicado en 2010

Sphingolipids as therapeutics

artículo científico publicado en 2003

Sphingolipids: regulators of crosstalk between apoptosis and autophagy

artículo científico publicado en 2012

Sphingosine Kinase 1 Cooperates with Autophagy to Maintain Endocytic Membrane Trafficking

artículo científico publicado en 2016

State-dependent block of HERG potassium channels by R-roscovitine: implications for cancer therapy

artículo científico publicado en 2009

Successful chemoimmunotherapy against hepatocellular cancer in a novel murine model

artículo científico publicado en 2016

Synergistic combination therapy with nanoliposomal C6-ceramide and vinblastine is associated with autophagy dysfunction in hepatocarcinoma and colorectal cancer models

artículo científico publicado en 2013

Systemic delivery of liposomal short-chain ceramide limits solid tumor growth in murine models of breast adenocarcinoma.

artículo científico publicado en 2005

Tamoxifen magnifies therapeutic impact of ceramide in human colorectal cancer cells independent of p53.

artículo científico publicado en 2013

Targeting V600EB-Raf and Akt3 using nanoliposomal-small interfering RNA inhibits cutaneous melanocytic lesion development.

artículo científico publicado en 2008

Targeting glucosylceramide synthase synergizes with C6-ceramide nanoliposomes to induce apoptosis in natural killer cell leukemia

artículo científico publicado en 2012

Targeting of survivin by nanoliposomal ceramide induces complete remission in a rat model of NK-LGL leukemia

artículo científico publicado en 2010

The apoptotic mechanism of action of the sphingosine kinase 1 selective inhibitor SKI-178 in human acute myeloid leukemia cell lines

artículo científico publicado en 2015

The therapeutic potential of nanoscale sphingolipid technologies

artículo científico publicado en 2013

The use of nanoparticulates to treat breast cancer

artículo científico publicado en 2017

Therapeutic Effect of Blueberry Extracts for Acute Myeloid Leukemia

Therapeutic efficacy of FTY720 in a rat model of NK-cell leukemia

artículo científico publicado en 2011

Therapeutic implications of bioactive sphingolipids: A focus on colorectal cancer

artículo científico publicado en 2017

Therapeutic strategies for diabetes and complications: a role for sphingolipids?

artículo científico publicado en 2010

Thermoresponsive and biodegradable linear-dendritic nanoparticles for targeted and sustained release of a pro-apoptotic drug

artículo científico publicado en 2007

Toll-like receptors at the ocular surface

artículo científico publicado en 2008

Transcriptional regulation of the human neutral ceramidase gene

artículo científico publicado en 2011

Use of an alumina-on-alumina bearing system in total hip arthroplasty for osteonecrosis of the hip.

artículo científico publicado en 2006

Use of high performance liquid chromatography-electrospray ionization-tandem mass spectrometry for the analysis of ceramide-1-phosphate levels

artículo científico publicado en 2009

Vemurafenib (PLX4032): an orally available inhibitor of mutated BRAF for the treatment of metastatic melanoma

artículo científico

Lista de obras de Mark Kester

A Cholecystokinin B Receptor-Specific DNA Aptamer for Targeting Pancreatic Ductal Adenocarcinoma

A novel biologically active acid stable liposomal formulation of docosahexaenoic acid in human breast cancer cell lines

AP-1 binding transcriptionally regulates human neutral ceramidase

Altered sphingolipid metabolism in patients with metastatic pancreatic cancer

Autophagosomal membrane serves as platform for intracellular death-inducing signaling complex (iDISC)-mediated caspase-8 activation and apoptosis

Bif-1 regulates Atg9 trafficking by mediating the fission of Golgi membranes during autophagy

C(6)-Ceramide-Coated Catheters Promote Re-Endothelialization of Stretch-Injured Arteries

C6-ceramide nanoliposomes target the Warburg effect in chronic lymphocytic leukemia

Calcium phosphate nanocomposite particles for in vitro imaging and encapsulated chemotherapeutic drug delivery to cancer cells

Calcium phosphate-based composite nanoparticles in bioimaging and therapeutic delivery applications

Calcium phosphosilicate nanoparticles for imaging and photodynamic therapy of cancer

Ceramide 1-phosphate mediates endothelial cell invasion via the annexin a2-p11 heterotetrameric protein complex

Ceramide kinase regulates TNFα-stimulated NADPH oxidase activity and eicosanoid biosynthesis in neuroblastoma cells

Ceramide modulates HERG potassium channel gating by translocation into lipid rafts

Ceramide nanoliposomes as a MLKL-dependent, necroptosis-inducing, chemotherapeutic reagent in ovarian cancer

Ceramide recruits and activates protein kinase C zeta (PKC zeta) within structured membrane microdomains

Ceramide--antiestrogen nanoliposomal combinations--novel impact of hormonal therapy in hormone-insensitive breast cancer

Ceramide-based therapeutics for the treatment of cancer

Ceramide-induced inhibition of Akt is mediated through protein kinase Czeta: implications for growth arrest

Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia

Characterization of insulin signaling in rat retina in vivo and ex vivo

Circulating sphingolipid biomarkers in models of type 1 diabetes

Clinical experience using a minimally invasive surgical approach for total knee arthroplasty: early results of a prospective randomized study compared to a standard approach

Clinical, objective, and functional outcomes of manipulation under anesthesia to treat knee stiffness following total knee arthroplasty

Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer ⬇️

Combining nanoliposomal ceramide with sorafenib synergistically inhibits melanoma and breast cancer cell survival to decrease tumor development

Delivery of PAR-4 plasmid in vivo via nanoliposomes sensitizes colon tumor cells subcutaneously implanted into nude mice to 5-FU.

Deregulated Akt3 activity promotes development of malignant melanoma

Development and use of ceramide nanoliposomes in cancer.

Diabetes alters sphingolipid metabolism in the retina: a potential mechanism of cell death in diabetic retinopathy

Diabetes diminishes phosphatidic acid in the retina: a putative mediator for reduced mTOR signaling and increased neuronal cell death

Diabetic retinopathy: seeing beyond glucose-induced microvascular disease.

Dynamics of ceramide generation and metabolism in response to fenretinide--Diversity within and among leukemia

Dysregulation of sphingolipid metabolism in cancer ⬇️

Effect of IL-1beta on survival and energy metabolism of R28 and RGC-5 retinal neurons

Effective encapsulation and biological activity of phosphorylated chemotherapeutics in calcium phosphosilicate nanoparticles for the treatment of pancreatic cancer

Emerging technologies in arthroplasty: additive manufacturing

Encapsulation of organic molecules in calcium phosphate nanocomposite particles for intracellular imaging and drug delivery

Engraftment of Human Primary Acute Myeloid Leukemia Defined by Integrated Genetic Profiling in NOD/SCID/IL2rγnull Mice for Preclinical Ceramide-Based Therapeutic Evaluation.

Ether-linked diglycerides inhibit vascular smooth muscle cell growth via decreased MAPK and PI3K/Akt signaling

Exogenous ceramide-1-phosphate reduces lipopolysaccharide (LPS)-mediated cytokine expression

Formation and role of exosomes in cancer

Growth of human pancreatic cancer is inhibited by down-regulation of gastrin gene expression

Inhibition of NADPH oxidase by glucosylceramide confers chemoresistance ⬇️

Inhibition of corneal inflammation by liposomal delivery of short-chain, C-6 ceramide

Innovations in knee arthroplasty: three-dimensional modeling and analytical technology (SOMA).

Liposomal Delivery of Diacylglycerol Lipase-Beta Inhibitors to Macrophages Dramatically Enhances Selectivity and Efficacy in Vivo

Liposomal delivery enhances short-chain ceramide-induced apoptosis of breast cancer cells

Long-term outcomes of MUA for stiffness in primary TKA.

Lysosomal degradation of CD44 mediates ceramide nanoliposome-induced anoikis and diminished extravasation in metastatic carcinoma cells

Minimally invasive total knee arthroplasty.

Modification of sphingolipid metabolism by tamoxifen and N-desmethyltamoxifen in acute myelogenous leukemia--Impact on enzyme activity and response to cytotoxics

Nanoliposomal minocycline for ocular drug delivery

Nanoliposomal short-chain ceramide inhibits agonist-dependent translocation of neurotensin receptor 1 to structured membrane microdomains in breast cancer cells

Nanoliposome C6-Ceramide Increases the Anti-tumor Immune Response and Slows Growth of Liver Tumors in Mice

Nanoparticulate Alternatives for Drug Delivery ⬇️

Neurotensin receptor-1 inducible palmitoylation is required for efficient receptor-mediated mitogenic-signaling within structured membrane microdomains

Novel Sphingolipid-Based Cancer Therapeutics in the Personalized Medicine Era

Paralemmin interacts with D3 dopamine receptors: implications for membrane localization and cAMP signaling

Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway

Preclinical development of a C6-ceramide NanoLiposome, a novel sphingolipid therapeutic

Predicting the effect of tray malalignment on risk for bone damage and implant subsidence after total knee arthroplasty

Propagation of Undifferentiated Human Embryonic Stem Cells with Nano-Liposomal Ceramide

Rapid distribution of liposomal short-chain ceramide in vitro and in vivo

Regulatory role of sphingomyelin metabolites in hypoxia-induced vascular smooth muscle cell proliferation

Role of P-glycoprotein inhibitors in ceramide-based therapeutics for treatment of cancer

Rotational constraint of posterior-stabilized total knee prostheses

SKI-178: A Multitargeted Inhibitor of Sphingosine Kinase and Microtubule Dynamics Demonstrating Therapeutic Efficacy in Acute Myeloid Leukemia Models

STAT3 mediates C6-ceramide-induced cell death in chronic lymphocytic leukemia

Short-chain ceramides depress integrin cell surface expression and function in colorectal cancer cells

Single radius total knee arthroplasty: PCL sacrifice without substitution yields excellent outcomes minimum 8-year follow-up.

Sphingolipids as therapeutics

Sphingolipids: regulators of crosstalk between apoptosis and autophagy

Sphingosine Kinase 1 Cooperates with Autophagy to Maintain Endocytic Membrane Trafficking

State-dependent block of HERG potassium channels by R-roscovitine: implications for cancer therapy

Successful chemoimmunotherapy against hepatocellular cancer in a novel murine model

Synergistic combination therapy with nanoliposomal C6-ceramide and vinblastine is associated with autophagy dysfunction in hepatocarcinoma and colorectal cancer models

Systemic delivery of liposomal short-chain ceramide limits solid tumor growth in murine models of breast adenocarcinoma.

Tamoxifen magnifies therapeutic impact of ceramide in human colorectal cancer cells independent of p53.