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Lista de obras de Heather N Tinsley

A novel access to arylated and heteroarylated beta-carboline based PDE5 inhibitors.

artículo científico publicado en 2010

A novel sulindac derivative that does not inhibit cyclooxygenases but potently inhibits colon tumor cell growth and induces apoptosis with antitumor activity.

artículo científico publicado en 2009

A novel sulindac derivative that potently suppresses colon tumor cell growth by inhibiting cGMP phosphodiesterase and β-catenin transcriptional activity

artículo científico publicado en 2012

Chronic exposure to a high-fat diet induces hepatic steatosis, impairs nitric oxide bioavailability, and modifies the mitochondrial proteome in mice.

artículo científico publicado en 2011

Colon Tumor Cell Growth–Inhibitory Activity of Sulindac Sulfide and Other Nonsteroidal Anti-Inflammatory Drugs Is Associated with Phosphodiesterase 5 Inhibition ⬇️

artículo científico publicado el 28 de septiembre de 2010

Cyclic GMP signaling during human lactation and breast cancer: Implications for breast cancer prevention

scientific article published on 20 May 2019

Design and Synthesis of Substituted Pyridazinone-1-Acetylhydrazones as Novel Phosphodiesterase 4 Inhibitors

artículo científico publicado en 2015

Design, synthesis and structure-activity relationship of functionalized tetrahydro-β-carboline derivatives as novel PDE5 inhibitors.

artículo científico publicado en 2010

Discovery of colon tumor cell growth inhibitory agents through a combinatorial approach.

artículo científico publicado en 2009

Exploring the PDE5 H-pocket by ensemble docking and structure-based design and synthesis of novel β-carboline derivatives.

artículo científico publicado en 2012

Inhibition of PDE5 by Sulindac Sulfide Selectively Induces Apoptosis and Attenuates Oncogenic Wnt/β-Catenin–Mediated Transcription in Human Breast Tumor Cells ⬇️

artículo científico publicado el 19 de abril de 2011

Modulating the cyclic guanosine monophosphate substrate selectivity of the phosphodiesterase 3 inhibitors by pyridine, pyrido[2,3-d]pyrimidine derivatives and their effects upon the growth of HT-29 cancer cell line.

artículo científico publicado en 2013

NSAIDs: Old Drugs Reveal New Anticancer Targets.

artículo científico publicado en 2010

New NSAID targets and derivatives for colorectal cancer chemoprevention.

artículo científico publicado en 2013

Novel Therapeutics: NSAIDs, Derivatives, and Phosphodiesterases ⬇️

artículo científico publicado el 1 de diciembre de 2012

Ripped from the Headlines: Using Current Events and Deliberative Democracy to Improve Student Performance in and Perceptions of Nonmajors Biology Courses

artículo científico publicado en 2016

Sulindac sulfide selectively inhibits growth and induces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of protein kinase G

artículo científico publicado en 2009

Suppression of Wnt/beta-catenin signaling inhibits prostate cancer cell proliferation

artículo científico publicado en 2008

Synthesis and molecular modeling of novel tetrahydro-β-carboline derivatives with phosphodiesterase 5 inhibitory and anticancer properties.

artículo científico publicado en 2010

Synthesis, Molecular Modeling, and Biological Evaluation of Novel Tetrahydro-β-Carboline Hydantoin and Tetrahydro-β-Carboline Thiohydantoin Derivatives as Phosphodiesterase 5 Inhibitors.

artículo científico publicado en 2011

Synthesis, molecular modeling and biological evaluation of novel tadalafil analogues as phosphodiesterase 5 and colon tumor cell growth inhibitors, new stereochemical perspective.

artículo científico publicado en 2010

The role of cyclic nucleotide signaling pathways in cancer: targets for prevention and treatment

scientific article published on 26 February 2014

cGMP signaling as a target for the prevention and treatment of breast cancer

artículo científico

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