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Lista de obras de Katherine A Donovan

Acute pharmacological degradation of Helios destabilizes regulatory T cells

artículo científico publicado en 2021

Bruton tyrosine kinase degradation as a therapeutic strategy for cancer

artículo científico publicado en 2018

Chemically Induced Degradation of Anaplastic Lymphoma Kinase (ALK).

artículo científico publicado en 2018

Comparing the Conformational Stability of Pyruvate Kinase in the Gas Phase and in Solution

scientific article published on 17 January 2020

Conformational Dynamics and Allostery in Pyruvate Kinase.

artículo científico publicado en 2016

Continuous evolution of compact protein degradation tags regulated by selective molecular glues

artículo científico publicado en 2024

Development and Characterization of a Wee1 Kinase Degrader

artículo científico publicado en 2019

Development of Dual and Selective Degraders of Cyclin-Dependent Kinases 4 and 6

scientific article published on 29 March 2019

Discovery of an AKT Degrader with Prolonged Inhibition of Downstream Signaling

scientific article published on 16 December 2019

ER stress signaling promotes the survival of cancer 'persister cells' tolerant to EGFR tyrosine kinase inhibitors

artículo científico publicado en 2017

Effects of Beneficial Mutations in pykF Gene Vary over Time and across Replicate Populations in a Long-Term Experiment with Bacteria.

artículo científico publicado en 2017

Exploring Targeted Degradation Strategy for Oncogenic KRASG12C

artículo científico publicado en 2019

Genomic and Biochemical Analysis of the Diaminopimelate and Lysine Biosynthesis Pathway in Verrucomicrobium spinosum: Identification and Partial Characterization of L,L-Diaminopimelate Aminotransferase and UDP-N-Acetylmuramoylalanyl-D-glutamyl-2,6-m

artículo científico publicado en 2012

Grappling with anisotropic data, pseudo-merohedral twinning and pseudo-translational noncrystallographic symmetry: a case study involving pyruvate kinase.

artículo científico publicado en 2016

Homolog-Selective Degradation as a Strategy to Probe the Function of CDK6 in AML

artículo científico publicado en 2018

Plasticity in binding confers selectivity in ligand-induced protein degradation

artículo científico publicado en 2018

Small molecule degraders of the hepatitis C virus protease reduce susceptibility to resistance mutations

artículo científico publicado en 2019

Small-molecule-induced polymerization triggers degradation of BCL6

artículo científico publicado en 2020

Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15

artículo científico publicado en 2019

Structure-function analyses of two plant meso-diaminopimelate decarboxylase isoforms reveal that active-site gating provides stereochemical control

scientific article published on 08 April 2019

TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma

artículo científico publicado en 2021

Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models

artículo científico publicado en 2019

Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome

artículo científico publicado en 2018

The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K

scientific article published on 03 June 2020

The lid domain is important, but not essential, for catalysis of Escherichia coli pyruvate kinase

scientific article published on 25 September 2020

The purification, crystallization and preliminary X-ray diffraction analysis of two isoforms of meso-diaminopimelate decarboxylase from Arabidopsis thaliana

artículo científico publicado en 2014

pSILAC mass spectrometry reveals ZFP91 as IMiD-dependent substrate of the CRL4CRBN ubiquitin ligase

artículo científico publicado en 2017