Filtros de búsqueda

Lista de obras de Alan R Healy

A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.

artículo científico publicado en 2018

A Mechanistic Model for Colibactin-Induced Genotoxicity.

artículo científico publicado en 2016

Addendum: Synthesis and reactivity of precolibactin 886

scientific article published on 01 December 2019

An inter-subunit protein-peptide interface that stabilizes the specific activity and oligomerization of the AAA+ chaperone Reptin

scientific article published on 09 March 2019

ClbS Is a Cyclopropane Hydrolase That Confers Colibactin Resistance.

artículo científico publicado en 2017

Convergent and Modular Synthesis of Candidate Precolibactins. Structural Revision of Precolibactin A.

artículo científico publicado en 2016

Discovery of a novel ligand that modulates the protein-protein interactions of the AAA+ superfamily oncoprotein reptin

artículo científico publicado en 2015

Domain-Targeted Metabolomics Delineates the Heterocycle Assembly Steps of Colibactin Biosynthesis

artículo científico publicado en 2017

Model colibactins exhibit human cell genotoxicity in the absence of host bacteria

scientific article published on 20 November 2018

Molecular Basis of Gut Microbiome-Associated Colorectal Cancer: A Synthetic Perspective.

artículo científico publicado en 2017

Selective and Efficient Generation of ortho-Brominated para-Substituted Phenols in ACS-Grade Methanol

Stereochemical assignment of the protein-protein interaction inhibitor JBIR-22 by total synthesis.

artículo científico publicado en 2015

Structure and Functional Analysis of ClbQ, an Unusual Intermediate-Releasing Thioesterase from the Colibactin Biosynthetic Pathway

artículo científico

Structure elucidation of colibactin and its DNA cross-links

artículo científico publicado en 2019

Synthesis and reactivity of precolibactin 886

artículo científico publicado en 2019

Synthesis and structure-activity analysis of new phosphonium salts with potent activity against African trypanosomes.

artículo científico publicado en 2012

Synthetic studies on the bioactive tetramic acid JBIR-22 using a late stage Diels-Alder reaction.

artículo científico publicado en 2015

Total synthesis and biological evaluation of the tetramic acid based natural product harzianic acid and its stereoisomers

artículo científico publicado en 2015