Filtros de búsqueda

Lista de obras de Mignon L Loh

A genome-wide association study of susceptibility to acute lymphoblastic leukemia in adolescents and young adults

artículo científico publicado en 2014

A new system identification approach to identify genetic variants in sequencing studies for a binary phenotype

artículo científico publicado en 2014

ARID5B genetic polymorphisms contribute to racial disparities in the incidence and treatment outcome of childhood acute lymphoblastic leukemia

artículo científico publicado en 2012

Aberrant STAT5 and PI3K/mTOR pathway signaling occurs in human CRLF2-rearranged B-precursor acute lymphoblastic leukemia

artículo científico publicado en 2012

Absence of biallelic TCRgamma deletion predicts early treatment failure in pediatric T-cell acute lymphoblastic leukemia

artículo científico publicado en 2010

Activating mutations in RRAS underlie a phenotype within the RASopathy spectrum and contribute to leukaemogenesis

artículo científico publicado en 2014

Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia

artículo científico publicado en 2004

Advances in the genetics of high-risk childhood B-progenitor acute lymphoblastic leukemia and juvenile myelomonocytic leukemia: implications for therapy

artículo científico publicado en 2012

Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia

artículo científico publicado en 2011

Bedside to bench in juvenile myelomonocytic leukemia: insights into leukemogenesis from a rare pediatric leukemia

artículo científico publicado en 2014

Challenges and opportunities for international cooperative studies in pediatric hematopoeitic cell transplantation: priorities of the Westhafen Intercontinental Group

artículo científico publicado en 2013

Characterization of leukemias with ETV6-ABL1 fusion

artículo científico publicado en 2016

Childhood acute lymphoblastic leukemia: Integrating genomics into therapy

artículo científico publicado en 2015

Childhood myelodysplastic syndrome: focus on the approach to diagnosis and treatment of juvenile myelomonocytic leukemia

artículo científico publicado en 2010

Children's Oncology Group's 2013 blueprint for research: acute lymphoblastic leukemia

artículo científico publicado en 2012

Chromosome 12p deletions in TEL-AML1 childhood acute lymphoblastic leukemia are associated with retrotransposon elements and occur postnatally

artículo científico publicado en 2008

Clinical and Genetic Risk Factors for Acute Pancreatitis in Patients With Acute Lymphoblastic Leukemia

artículo científico publicado en 2016

Clonal evolution mechanisms in NT5C2 mutant-relapsed acute lymphoblastic leukaemia

artículo científico publicado en 2018

Criteria for evaluating response and outcome in clinical trials for children with juvenile myelomonocytic leukemia

artículo científico publicado en 2015

Deregulation of DUX4 and ERG in acute lymphoblastic leukemia

artículo científico publicado en 2016

Dexamethasone and High-Dose Methotrexate Improve Outcome for Children and Young Adults With High-Risk B-Acute Lymphoblastic Leukemia: A Report From Children's Oncology Group Study AALL0232

artículo científico publicado en 2016

Efficacy of JAK/STAT pathway inhibition in murine xenograft models of early T-cell precursor (ETP) acute lymphoblastic leukemia.

artículo científico publicado en 2015

Enhancer Hijacking Drives Oncogenic <i>BCL11B</i> Expression in Lineage-Ambiguous Stem Cell Leukemia

publication published on 08 June 2021

Evaluation of the in vitro and in vivo efficacy of the JAK inhibitor AZD1480 against JAK-mutated acute lymphoblastic leukemia

artículo científico publicado en 2014

Evolution of the epigenetic landscape in childhood B acute lymphoblastic leukemia and its role in drug resistance

scientific article published on 16 October 2020

Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia

artículo científico publicado en 2012

Genetic risk factors for the development of osteonecrosis in children under age 10 treated for acute lymphoblastic leukemia

artículo científico publicado en 2015

Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia

scientific journal article

Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia

artículo científico publicado en 2016

Genomic and outcome analyses of Ph-like ALL in NCI standard-risk patients: a report from the Children's Oncology Group

scientific article published on 11 July 2018

Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia

artículo científico publicado en 2010

Germline Genetic IKZF1 Variation and Predisposition to Childhood Acute Lymphoblastic Leukemia.

artículo científico publicado en 2018

Germline RRAS2 mutations are not associated with Noonan syndrome.

artículo científico publicado en 2016

Germline SAMD9 and SAMD9L mutations are associated with extensive genetic evolution and diverse hematologic outcomes

artículo científico publicado en 2018

Germline genetic variation in ETV6 and risk of childhood acute lymphoblastic leukaemia: a systematic genetic study

artículo científico publicado en 2015

HLA-DRB1*07:01 is associated with a higher risk of asparaginase allergies.

artículo científico publicado en 2014

Identification of cryptotanshinone as an inhibitor of oncogenic protein tyrosine phosphatase SHP2 (PTPN11).

artículo científico publicado en 2013

Impact of Initial CSF Findings on Outcome Among Patients With National Cancer Institute Standard- and High-Risk B-Cell Acute Lymphoblastic Leukemia: A Report From the Children's Oncology Group

artículo científico publicado en 2017

Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse

artículo científico publicado en 2013

Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children

artículo científico publicado en 2015

Integration of cytogenomic data for furthering the characterization of pediatric B-cell acute lymphoblastic leukemia: a multi-institution, multi-platform microarray study

artículo científico publicado en 2014

Intrachromosomal amplification of chromosome 21 is associated with inferior outcomes in children with acute lymphoblastic leukemia treated in contemporary standard-risk children's oncology group studies: a report from the children's oncology group

artículo científico publicado en 2013

JAK mutations in high-risk childhood acute lymphoblastic leukemia

scholarly article

Juvenile myelomonocytic leukemia: molecular pathogenesis informs current approaches to therapy and hematopoietic cell transplantation

artículo científico publicado en 2014

Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group

artículo científico publicado en 2011

MYBL2 is a sub-haploinsufficient tumor suppressor gene in myeloid malignancy

artículo científico publicado en 2013

Maturation stage of T-cell acute lymphoblastic leukemia determines BCL-2 versus BCL-XL dependence and sensitivity to ABT-199

artículo científico publicado en 2014

Mutational and functional genetics mapping of chemotherapy resistance mechanisms in relapsed acute lymphoblastic leukemia

artículo científico publicado en 2020

Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia

artículo científico publicado en 2016

Mutations in CBL occur frequently in juvenile myelomonocytic leukemia

artículo científico publicado en 2009

No evidence that G6PD deficiency affects the efficacy or safety of daunorubicin in acute lymphoblastic leukemia induction therapy

artículo científico publicado en 2019

Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations

scientific journal article

Oncogene regulation. An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element

artículo científico publicado en 2014

One year follow-up of children and adolescents with chronic immune thrombocytopenic purpura (ITP) treated with rituximab

artículo científico publicado en 2009

Outcome modeling with CRLF2, IKZF1, JAK, and minimal residual disease in pediatric acute lymphoblastic leukemia: a Children's Oncology Group study

artículo científico publicado en 2012

Outcome of patients treated for relapsed or refractory acute lymphoblastic leukemia: a Therapeutic Advances in Childhood Leukemia Consortium study

artículo científico publicado en 2009

PI3K p110δ uniquely promotes gain-of-function Shp2-induced GM-CSF hypersensitivity in a model of JMML.

artículo científico publicado en 2014

Pediatric MDS: GATA screen the germline

artículo científico publicado en 2016

Pharmacokinetic and pharmacodynamic properties of calaspargase pegol Escherichia coli L-asparaginase in the treatment of patients with acute lymphoblastic leukemia: results from Children's Oncology Group Study AALL07P4.

artículo científico publicado en 2014

Phase II/III trial of a pre-transplant farnesyl transferase inhibitor in juvenile myelomonocytic leukemia: a report from the Children's Oncology Group.

artículo científico publicado en 2014

Philadelphia chromosome-like acute lymphoblastic leukemia

artículo científico publicado en 2017

Potent efficacy of combined PI3K/mTOR and JAK or ABL inhibition in murine xenograft models of Ph-like acute lymphoblastic leukemia

artículo científico publicado en 2016

Prognostic impact of kinase-activating fusions and IKZF1 deletions in pediatric high-risk B-lineage acute lymphoblastic leukemia

artículo científico publicado en 2018

Prognostic significance of minimal residual disease in high risk B-ALL: a report from Children's Oncology Group study AALL0232.

artículo científico publicado en 2015

Prospective phase 1/2 study of rituximab in childhood and adolescent chronic immune thrombocytopenic purpura

artículo científico publicado en 2005

Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukaemia.

artículo científico publicado en 2015

SHP-2 and myeloid malignancies

artículo científico publicado en 2004

Safe integration of nelarabine into intensive chemotherapy in newly diagnosed T-cell acute lymphoblastic leukemia: Children's Oncology Group Study AALL0434

artículo científico publicado en 2015

Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia

artículo científico publicado en 2015

Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia

artículo científico publicado en 2014

Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia

artículo científico publicado en 2017

TEL/AML1-positive pediatric leukemia: prognostic significance and therapeutic approaches

artículo científico publicado en 2002

TP53 Germline Variations Influence the Predisposition and Prognosis of B-Cell Acute Lymphoblastic Leukemia in Children

artículo científico publicado en 2018

Targetable kinase gene fusions in high-risk B-ALL: a study from the Children's Oncology Group

artículo científico publicado en 2017

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia

artículo científico publicado en 2014

Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia

artículo científico publicado en 2012

Targeting survivin overcomes drug resistance in acute lymphoblastic leukemia

artículo científico publicado en 2011

The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemia

artículo científico publicado en 2005

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

artículo científico publicado en 2012

The genomic landscape of hypodiploid acute lymphoblastic leukemia

artículo científico publicado en 2013

Treatment of infantile fibrosarcoma with chemotherapy and surgery: results from the Dana-Farber Cancer Institute and Children's Hospital, Boston

artículo científico publicado en 2002

Truncating Erythropoietin Receptor Rearrangements in Acute Lymphoblastic Leukemia

artículo científico publicado en 2016

Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group TARGET Project

artículo científico publicado en 2012

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda