Lista de obras - Timothy J. Snape - Dominio Público Uruguay

2-Arylindoles: a privileged molecular scaffold with potent, broad-ranging pharmacological activity.

artículo científico publicado en 2012

A template-based mnemonic for monoamine oxidase (MAO-N) catalyzed reactions and its application to the chemo-enzymatic deracemisation of the alkaloid (±)-crispine A

scientific article published on 08 August 2007

A truce on the Smiles rearrangement: revisiting an old reaction--the Truce-Smiles rearrangement.

scientific article published on 15 September 2008

Achieving conformational control over C–C, C–N and C–O bonds in biaryls, N,N′-diarylureas and diaryl ethers: advantages of a relay axis

artículo científico publicado en 2006

Anionic Host Defence Peptides from the Plant Kingdom: Their Anticancer Activity and Mechanisms of Action

artículo científico publicado en 2016

Application of the semi-pinacol rearrangement towards the generation of alkenyl-substituted quaternary carbon centres

scientific article published on 01 November 2006

Approaches toward improving the prognosis of pediatric patients with glioma: pursuing mutant drug targets with emerging small molecules

artículo científico

Aromatic amides and ureas as novel molecular probes for diagnosing disease

scientific article published on 13 October 2014

Cn-AMP2 from green coconut water is an anionic anticancer peptide.

artículo científico publicado en 2014

Development of a novel, multifunctional, membrane-interactive pyridinium salt with potent anticancer activity.

artículo científico publicado en 2014

Enzymatic Oxidation Chemistry

Foldamers as Anticancer Therapeutics: Targeting Protein-Protein Interactions and the Cell Membrane.

artículo científico publicado en 2015

Functional foldamers that target bacterial membranes: The effect of charge, amphiphilicity and conformation.

artículo científico publicado en 2016

Functionalising the azobenzene motif delivers a light-responsive membrane-interactive compound with the potential for photodynamic therapy applications

artículo científico publicado en 2015

Helix persistence and breakdown in oligoureas of metaphenylenediamine: apparent diastereotopicity as a spectroscopic marker of helix length in solution

artículo científico publicado en 2008

Heterocyclic scaffolds as promising anticancer agents against tumours of the central nervous system: Exploring the scope of indole and carbazole derivatives.

artículo científico publicado en 2014

Identification of C-β-d-Glucopyranosyl Azole-Type Inhibitors of Glycogen Phosphorylase That Reduce Glycogenolysis in Hepatocytes: In Silico Design, Synthesis, in Vitro Kinetics, and ex Vivo Studies

scientific article published on 19 June 2019

Induction of apoptosis in estrogen receptor-negative breast cancer cells by natural and synthetic cyclopentenones: role of the IkappaB kinase/nuclear factor-kappaB pathway

scientific article published on 14 August 2006

Preliminary biological evaluation and mechanism of action studies of selected 2-arylindoles against glioblastoma.

artículo científico publicado en 2013

Recent advances in the semi-pinacol rearrangement of alpha-hydroxy epoxides and related compounds.

artículo científico publicado en 2007

Small-molecule clinical trial candidates for the treatment of glioma

artículo científico

Synthetic oligoureas of metaphenylenediamine mimic host defence peptides in their antimicrobial behaviour.

artículo científico publicado en 2013

Towards identifying potent new hits for glioblastoma

scientific article published on 02 October 2018

Versatility of a new bioinorganic catalyst: palladized cells of Desulfovibrio desulfuricans and application to dehalogenation of flame retardant materials

artículo científico publicado en 2009

Lista de obras de Timothy J. Snape

2-Arylindoles: a privileged molecular scaffold with potent, broad-ranging pharmacological activity.

A template-based mnemonic for monoamine oxidase (MAO-N) catalyzed reactions and its application to the chemo-enzymatic deracemisation of the alkaloid (±)-crispine A

A truce on the Smiles rearrangement: revisiting an old reaction--the Truce-Smiles rearrangement.

Achieving conformational control over C–C, C–N and C–O bonds in biaryls, N,N′-diarylureas and diaryl ethers: advantages of a relay axis

Anionic Host Defence Peptides from the Plant Kingdom: Their Anticancer Activity and Mechanisms of Action

Application of the semi-pinacol rearrangement towards the generation of alkenyl-substituted quaternary carbon centres

Approaches toward improving the prognosis of pediatric patients with glioma: pursuing mutant drug targets with emerging small molecules

Aromatic amides and ureas as novel molecular probes for diagnosing disease

Cn-AMP2 from green coconut water is an anionic anticancer peptide.

Development of a novel, multifunctional, membrane-interactive pyridinium salt with potent anticancer activity.

Enzymatic Oxidation Chemistry

Foldamers as Anticancer Therapeutics: Targeting Protein-Protein Interactions and the Cell Membrane.

Functional foldamers that target bacterial membranes: The effect of charge, amphiphilicity and conformation.

Functionalising the azobenzene motif delivers a light-responsive membrane-interactive compound with the potential for photodynamic therapy applications

Helix persistence and breakdown in oligoureas of metaphenylenediamine: apparent diastereotopicity as a spectroscopic marker of helix length in solution

Heterocyclic scaffolds as promising anticancer agents against tumours of the central nervous system: Exploring the scope of indole and carbazole derivatives.

Identification of C-β-d-Glucopyranosyl Azole-Type Inhibitors of Glycogen Phosphorylase That Reduce Glycogenolysis in Hepatocytes: In Silico Design, Synthesis, in Vitro Kinetics, and ex Vivo Studies

Induction of apoptosis in estrogen receptor-negative breast cancer cells by natural and synthetic cyclopentenones: role of the IkappaB kinase/nuclear factor-kappaB pathway

Preliminary biological evaluation and mechanism of action studies of selected 2-arylindoles against glioblastoma.

Recent advances in the semi-pinacol rearrangement of alpha-hydroxy epoxides and related compounds.

Small-molecule clinical trial candidates for the treatment of glioma

Synthetic oligoureas of metaphenylenediamine mimic host defence peptides in their antimicrobial behaviour.

Towards identifying potent new hits for glioblastoma

Versatility of a new bioinorganic catalyst: palladized cells of Desulfovibrio desulfuricans and application to dehalogenation of flame retardant materials