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Lista de obras de Kunio Matsumoto

3-D collagen-dependent cell surface expression of MT1-MMP and MMP-2 activation regardless of integrin β1 function and matrix stiffness ⬇️

artículo científico publicado el 23 de julio de 2011

A Novel Prostacyclin Agonist Protects against Airway Hyperresponsiveness and Remodeling in Mice ⬇️

artículo científico publicado el 8 de marzo de 2012

A Novel Vascular Modulator, Hepatocyte Growth Factor (HGF), as a Potential Index of the Severity of Hypertension ⬇️

artículo científico publicado el 6 de enero de 1998

A clinical protocol to inhibit the HGF/c-Met pathway for malignant mesothelioma with an intrapleural injection of adenoviruses expressing the NK4 gene.

artículo científico publicado en 2015

A potential cardioprotective role of hepatocyte growth factor in myocardial infarction in rats

artículo científico publicado en 2001

A synthetic prostacyclin agonist with thromboxane synthase inhibitory activity, ONO-1301, protects myocardium from ischemia/reperfusion injury

artículo científico publicado en 2011

Ability of the Met kinase inhibitor crizotinib and new generation EGFR inhibitors to overcome resistance to EGFR inhibitors.

artículo científico publicado en 2013

Abrogation of Fas-Induced Fulminant Hepatic Failure in Mice by Hepatocyte Growth Factor ⬇️

artículo científico publicado el 27 de marzo de 1998

Actions of hepatocyte growth factor as a local modulator in the kidney: Potential role in pathogenesis of renal disease ⬇️

artículo científico publicado el 1 de enero de 1998

Angiogenesis and antifibrotic action by hepatocyte growth factor in cardiomyopathy.

artículo científico publicado en 2002

Angiogenic and antifibrotic actions of hepatocyte growth factor improve cardiac dysfunction in porcine ischemic cardiomyopathy.

artículo científico publicado en 2006

Angiogenic property of hepatocyte growth factor is dependent on upregulation of essential transcription factor for angiogenesis, ets-1.

artículo científico publicado en 2003

Angioinhibitory action of NK4 involves impaired extracellular assembly of fibronectin mediated by perlecan-NK4 association.

artículo científico publicado en 2009

Arterial shear stress augments the differentiation of endothelial progenitor cells adhered to VEGF-bound surfaces ⬇️

artículo científico publicado el 23 de mayo de 2012

Artificial human Met agonists based on macrocycle scaffolds

artículo científico publicado en 2015

Beneficial effect of a synthetic prostacyclin agonist, ONO-1301, in rat autoimmune myocarditis model.

artículo científico publicado en 2012

Bi-directional regulation of Ser-985 phosphorylation of c-met via protein kinase C and protein phosphatase 2A involves c-Met activation and cellular responsiveness to hepatocyte growth factor.

artículo científico publicado en 2004

Biological and clinical significance of hepatocyte growth factor in breast cancer ⬇️

artículo científico publicado el 1 de diciembre de 1997

Cellular signaling and gene expression profiles evoked by a bivalent macrocyclic peptide that serves as an artificial MET receptor agonist

artículo científico publicado en 2018

Chemotherapeutic agents potentiate adenoviral gene therapy for pancreatic cancer.

artículo científico publicado en 2009

Co-cultivation of pancreatic cancer cells with orthotopic tumor-derived fibroblasts: fibroblasts stimulate tumor cell invasion via HGF secretion whereas cancer cells exert a minor regulative effect on fibroblasts HGF production

artículo científico publicado en 2003

Coexpression of hepatocyte growth factor and c‐Met proto‐oncogene product in synovial sarcoma ⬇️

artículo científico publicado el 1 de octubre de 1998

Combined therapy with mutant-selective EGFR inhibitor and Met kinase inhibitor for overcoming erlotinib resistance in EGFR-mutant lung cancer.

artículo científico publicado en 2012

Contact inhibition of hepatocyte growth regulated by functional association of the c-Met/hepatocyte growth factor receptor and LAR protein-tyrosine phosphatase

scientific journal article

Cooperative Interaction between α- and β-Chains of Hepatocyte Growth Factor on c-Met Receptor Confers Ligand-induced Receptor Tyrosine Phosphorylation and Multiple Biological Responses ⬇️

artículo científico publicado el 4 de septiembre de 1998

Cross-activating c-Met/β1 integrin complex drives metastasis and invasive resistance in cancer.

artículo científico publicado en 2017

Cyclic Peptide-Based Biologics Regulating HGF-MET

artículo científico publicado en 2020

De novo peptide grafting to a self-assembling nanocapsule yields a hepatocyte growth factor receptor agonist

artículo científico publicado en 2021

Development of safe and efficient novel nonviral gene transfer using ultrasound: enhancement of transfection efficiency of naked plasmid DNA in skeletal muscle.

artículo científico publicado en 2002

Different reactivities of enzyme-linked immunosorbent assays for hepatocyte growth factor.

artículo científico publicado en 2008

Distinct Localization of Mature HGF from its Precursor Form in Developing and Repairing the Stomach

scientific article published on 17 June 2019

Dual inhibition of Met kinase and angiogenesis to overcome HGF-induced EGFR-TKI resistance in EGFR mutant lung cancer.

artículo científico publicado en 2012

Effects of hepatocyte growth factor on E-cadherin-mediated cell-cell adhesion in DU145 prostate cancer cells ⬇️

artículo científico publicado el 1 de diciembre de 2001

Enhanced angiogenesis and improvement of neuropathy by cotransfection of human hepatocyte growth factor and prostacyclin synthase gene.

artículo científico publicado en 2003

Enhanced suppression of tumor growth using a combination of NK4 plasmid DNA-PEG engrafted cationized dextran complex and ultrasound irradiation.

artículo científico publicado en 2006

Essential role of HGF (hepatocyte growth factor) in blood formation in Xenopus.

artículo científico

Facilitated tendon-bone healing by local delivery of recombinant hepatocyte growth factor in rabbits.

artículo científico publicado en 2010

Gallbladder cancer treatment using adenovirus expressing the HGF/NK4 gene in a peritoneal implantation model.

artículo científico publicado en 2004

Gemcitabine synergistically enhances the effect of adenovirus gene therapy through activation of the CMV promoter in pancreatic cancer cells.

artículo científico publicado en 2010

Gene therapy for preventing neuronal death using hepatocyte growth factor: in vivo gene transfer of HGF to subarachnoid space prevents delayed neuronal death in gerbil hippocampal CA1 neurons.

artículo científico publicado en 2001

Gene transduction of NK4, HGF antagonist, inhibits in vitro invasion and in vivo growth of human pancreatic cancer.

artículo científico publicado en 2002

Gene transfer of NK4, an angiogenesis inhibitor, induces CT26 tumor regression via tumor-specific T lymphocyte activation.

artículo científico publicado en 2009

Gene transfer of hepatocyte growth factor to subarachnoid space in cerebral hypoperfusion model.

artículo científico publicado en 2002

Gene transfer of human hepatocyte growth factor into rat skin wounds mediated by liposomes coated with the sendai virus (hemagglutinating virus of Japan).

artículo científico publicado en 2002

Growth factors temporally associate with airway responsiveness and inflammation in allergen-exposed mice

artículo científico publicado en 2007

Growth inhibition and apoptosis in liver myofibroblasts promoted by hepatocyte growth factor leads to resolution from liver cirrhosis.

artículo científico publicado en 2005

HGF reduces advancing lung fibrosis in mice: a potential role for MMP-dependent myofibroblast apoptosis.

artículo científico publicado en 2005

HGF regulates VEGF expression via the c-Met receptor downstream pathways, PI3K/Akt, MAPK and STAT3, in CT26 murine cells ⬇️

artículo científico publicado el 6 de diciembre de 2012

HGF/NK4 inhibited VEGF-induced angiogenesis in in vitro cultured endothelial cells and in vivo rabbit model.

artículo científico publicado en 2002

HGF/NK4 is a specific antagonist for pleiotrophic actions of hepatocyte growth factor ⬇️

artículo científico publicado el 22 de diciembre de 1997

Hepatocyte Growth Factor (HGF) as a Tissue Organizer for Organogenesis and Regeneration ⬇️

artículo científico publicado el 29 de octubre de 1997

Hepatocyte growth factor and Met in tumor biology and therapeutic approach with NK4.

artículo científico publicado en 2008

Hepatocyte growth factor and the Met system as a mediator of tumor-stromal interactions.

artículo científico publicado en 2006

Hepatocyte growth factor attenuates cerebral ischemia-induced increase in permeability of the blood-brain barrier and decreases in expression of tight junctional proteins in cerebral vessels.

artículo científico publicado en 2006

Hepatocyte growth factor contributes to fracture repair by upregulating the expression of BMP receptors.

artículo científico publicado en 2005

Hepatocyte growth factor exerts a proliferative effect on oval cells through the PI3K/AKT signaling pathway.

artículo científico publicado en 2003

Hepatocyte growth factor facilitates cartilage repair: Full thickness articular cartilage defect studied in rabbit knees ⬇️

artículo científico publicado el 1 de octubre de 1997

Hepatocyte growth factor gene transfer to alveolar septa for effective suppression of lung fibrosis.

artículo científico publicado en 2005

Hepatocyte growth factor improved learning and memory dysfunction of microsphere-embolized rats

artículo científico publicado en 2004

Hepatocyte growth factor improves synaptic localization of the NMDA receptor and intracellular signaling after excitotoxic injury in cultured hippocampal neurons.

artículo científico publicado en 2007

Hepatocyte growth factor in physiology and infectious diseases.

artículo científico publicado en 2017

Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptor-activating mutations.

artículo científico publicado en 2008

Hepatocyte growth factor induces resistance to anti-epidermal growth factor receptor antibody in lung cancer.

artículo científico publicado en 2012

Hepatocyte growth factor plays roles in the induction and autocrine maintenance of bone marrow stromal cell IL-11, SDF-1 alpha, and stem cell factor.

artículo científico publicado en 2004

Hepatocyte growth factor prevents multiple organ injuries in endotoxemic mice through a heme oxygenase-1-dependent mechanism

artículo científico publicado en 2009

Hepatocyte growth factor prevents pulmonary ischemia-reperfusion injury in mice

artículo científico publicado en 2007

Hepatocyte growth factor prevents renal fibrosis and dysfunction in a mouse model of chronic renal disease ⬇️

artículo científico publicado el 1 de mayo de 1998

Hepatocyte growth factor prevents tissue fibrosis, remodeling, and dysfunction in cardiomyopathic hamster hearts.

artículo científico publicado en 2005

Hepatocyte growth factor promotes the number of PSD-95 clusters in young hippocampal neurons

scientific article published on 26 June 2007

Hepatocyte growth factor receptor is a coreceptor for adeno-associated virus type 2 infection.

artículo científico publicado en 2005

Hepatocyte growth factor reduces susceptibility to an irreversible epidermal growth factor receptor inhibitor in EGFR-T790M mutant lung cancer.

artículo científico publicado en 2009

Hepatocyte growth factor reduces the infarct volume after transient focal cerebral ischemia in rats.

artículo científico publicado en 2001

Hepatocyte growth factor stimulates the invasion of gallbladder carcinoma cell lines in vitro

artículo científico publicado el 1 de enero de 1998

Hepatocyte growth factor suppresses interstitial fibrosis in a mouse model of obstructive nephropathy

artículo científico publicado en 2001

Hepatocyte growth factor twenty years on: Much more than a growth factor ⬇️

artículo científico publicado el 1 de enero de 2011

Hepatocyte growth factor/MET in cancer progression and biomarker discovery

scientific article published on 08 January 2017

Hsp90 Inhibition Overcomes HGF-Triggering Resistance to EGFR-TKIs in EGFR-Mutant Lung Cancer by Decreasing Client Protein Expression and Angiogenesis

artículo científico publicado en 2012

Identification of tumor-initiating cells in a highly aggressive brain tumor using promoter activity of nucleostemin.

artículo científico publicado en 2009

Impact of Serum Hepatocyte Growth Factor on Treatment Response to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Patients with Non–Small Cell Lung Adenocarcinoma ⬇️

artículo científico publicado el 2 de agosto de 2010

Impaired ligand-dependent MET activation caused by an extracellular SEMA domain missense mutation in lung cancer

scientific article published on 13 August 2019

In vivo evidence of angiogenesis induced by transcription factor Ets-1: Ets-1 is located upstream of angiogenesis cascade.

artículo científico publicado en 2004

Induction of Donor-Specific Tolerance Using Superagonistic CD28 Antibody in Rat Renal Allografts: Regulatory T-Cell Expansion Before Engraftment May Be Important ⬇️

artículo científico publicado el 27 de diciembre de 2010

Inhibition of apoptosis-inducing factor translocation is involved in protective effects of hepatocyte growth factor against excitotoxic cell death in cultured hippocampal neurons.

artículo científico publicado en 2005

Inhibition of neointimal formation after balloon injury by cilostazol, accompanied by improvement of endothelial dysfunction and induction of hepatocyte growth factor in rat diabetes model.

artículo científico publicado en 2001

Inhibition of transforming growth factor-β signaling potentiates tumor cell invasion into collagen matrix induced by fibroblast-derived hepatocyte growth factor.

artículo científico publicado en 2014

Interruption of the HGF paracrine loop by NK4, an HGF antagonist, reduces VEGF expression of CT26 cells.

artículo científico publicado en 2013

Intraperitoneal injection of adenovirus-mediated NK4 gene suppresses peritoneal dissemination of pancreatic cancer cell line AsPC-1 in nude mice.

artículo científico publicado en 2002

Intraventricular administration of hepatocyte growth factor treats mouse communicating hydrocephalus induced by transforming growth factor beta1.

artículo científico publicado en 2005

Involvement of hepatocyte growth factor in branching morphogenesis of murine salivary gland

artículo científico publicado en 2003

Lack of association between the hepatocyte growth factor receptor, c-met, and the anti-apoptotic action of bag-1 in endothelial cells.

artículo científico publicado en 2004

Liver organogenesis promoted by endothelial cells prior to vascular function.

artículo científico publicado en 2001

Liver targeting of plasmid DNA with a cationized pullulan for tumor suppression

artículo científico publicado en 2006

Lower gefitinib dose led to earlier resistance acquisition before emergence of T790M mutation in epidermal growth factor receptor-mutated lung cancer model

artículo científico publicado en 2013

MET Activation by a Macrocyclic Peptide Agonist that Couples to Biological Responses Differently from HGF in a Context-Dependent Manner

article

Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor

artículo científico publicado en 2019

Mechanisms and significance of bifunctional NK4 in cancer treatment.

artículo científico publicado en 2005

Met kinase inhibitor E7050 reverses three different mechanisms of hepatocyte growth factor-induced tyrosine kinase inhibitor resistance in EGFR mutant lung cancer.

artículo científico publicado en 2012

Met/HGF receptor activation is regulated by juxtamembrane Ser985 phosphorylation in hepatocytes.

artículo científico publicado en 2013

Molecular targeting of hepatocyte growth factor by an antagonist, NK4, in the treatment of rheumatoid arthritis ⬇️

artículo científico publicado el 22 de julio de 2013

N-glycosylation regulates MET processing and signaling

artículo científico publicado en 2022

NK4 gene therapy targeting HGF-Met and angiogenesis.

artículo científico publicado en 2008

NK4, an antagonist of hepatocyte growth factor (HGF), inhibits growth of multiple myeloma cells: molecular targeting of angiogenic growth factor.

artículo científico publicado en 2007

No influence of tumor growth by intramuscular injection of hepatocyte growth factor plasmid DNA: safety evaluation of therapeutic angiogenesis gene therapy in mice.

artículo científico publicado en 2004

Non-Small Cell Lung Cancer Cells Acquire Resistance to the ALK Inhibitor Alectinib by Activating Alternative Receptor Tyrosine Kinases

artículo científico publicado en 2015

Novel long-acting prostacyclin agonist (ONO-1301) with an angiogenic effect: promoting synthesis of hepatocyte growth factor and increasing cyclic AMP concentration via IP-receptor signaling.

artículo científico publicado en 2013

Oral Administration of a Novel Long-Acting Prostacyclin Agonist With Thromboxane Synthase Inhibitory Activity for Pulmonary Arterial Hypertension ⬇️

artículo científico publicado el 16 de mayo de 2013

Paracrine activation of MET promotes peritoneal carcinomatosis in scirrhous gastric cancer.

artículo científico publicado en 2013

Paracrine receptor activation by microenvironment triggers bypass survival signals and ALK inhibitor resistance in EML4-ALK lung cancer cells.

artículo científico publicado en 2012

Pharmacokinetic modeling of hepatocyte growth factor in experimental animals and humans.

artículo científico publicado en 2012

Pharmacokinetics and pharmacodynamics following intravenous administration of recombinant human hepatocyte growth factor in rats with renal injury

artículo científico publicado en 2014

Pleural Mesothelioma Instigates Tumor-Associated Fibroblasts To Promote Progression via a Malignant Cytokine Network ⬇️

artículo científico publicado el 18 de julio de 2011

Possible effects of hepatocyte growth factor for the prevention of peritoneal fibrosis

scientific article published on 19 January 2005

Potential Role of a Novel Vascular Modulator, Hepatocyte Growth Factor (HGF), in Cardiovascular Disease : Characterization and Regulation of Local HGF System ⬇️

artículo científico publicado el 1 de enero de 1997

Potential role of hepatocyte growth factor in the maintenance of renal structure: Anti-apoptotic action of HGF on epithelial cells ⬇️

artículo científico publicado el 1 de octubre de 1998

Preventive and therapeutic effects in rats of hepatocyte growth factor infusion on liver fibrosis/cirrhosis ⬇️

artículo científico publicado el 1 de julio de 1997

Promotion of rabbit ligament healing by local delivery of hepatocyte growth factor

artículo científico publicado en 2011

Protamine enhances the proliferative activity of hepatocyte growth factor in rats ⬇️

artículo científico publicado el 1 de enero de 1998

Proteasomal degradation of polycomb-group protein CBX6 confers MMP-2 expression essential for mesothelioma invasion

artículo científico publicado en 2020

Radiation stimulates HGF receptor/c-Met expression that leads to amplifying cellular response to HGF stimulation via upregulated receptor tyrosine phosphorylation and MAP kinase activity in pancreatic cancer cells.

artículo científico publicado en 2003

Recombinant human hepatocyte growth factor (HGF), but not rat HGF, elicits glomerular injury and albuminuria in normal rats via an immune complex-dependent mechanism.

artículo científico publicado en 2011

Reduced HGF expression in subcutaneous CT26 tumor genetically modified to secrete NK4 and its possible relation with antitumor effects.

artículo científico publicado en 2004

Reduction of fibrosis in a rat model of non-alcoholic steatohepatitis cirrhosis by human HGF gene transfection using electroporation.

artículo científico publicado en 2007

Regulation of cell migration and cytokine production by HGF-like protein (HLP) / macrophage stimulating protein (MSP) in primary microglia.

artículo científico publicado en 2008

Regulation of lnvasive Potential of Human Prostate Cancer Cell Lines by Hepatocyte Growth Factor ⬇️

artículo científico publicado el 1 de mayo de 1998

Renotropic role and therapeutic potential of HGF in the kidney

scientific article published on 01 January 2002

Repair of segmental bone defects in rabbit tibia promoted by a complex of β-tricalcium phosphate and hepatocyte growth factor

artículo científico publicado en 2012

Role of Angiotensin II in the Regulation of a Novel Vascular Modulator, Hepatocyte Growth Factor (HGF), in Experimental Hypertensive Rats ⬇️

artículo científico publicado el 1 de diciembre de 1997

Role of hepatocyte growth factor in endothelial regulation: prevention of high D-glucose-induced endothelial cell death by prostaglandins and phosphodiesterase type 3 inhibitor ⬇️

artículo científico publicado el 1 de septiembre de 1997

Simultaneous or Delayed Administration of Hepatocyte Growth Factor Equally Represses the Fibrotic Changes in Murine Lung Injury Induced by Bleomycin ⬇️

artículo científico publicado el 1 de diciembre de 1997

Stimulation by Histamine of TPA-dependent Hepatocyte Growth Factor Production in Promyelocytic Leukemia HL-60 Cells ⬇️

artículo científico publicado el 1 de julio de 1998

Stimulation of hepatocyte growth factor production by heparin-derived oligosaccharides.

artículo científico publicado en 2007

Suppression of acute and chronic rejection by hepatocyte growth factor in a murine model of cardiac transplantation: induction of tolerance and prevention of cardiac allograft vasculopathy

artículo científico publicado en 2004

Suppression of acute hepatic injury by a synthetic prostacyclin agonist through hepatocyte growth factor expression.

artículo científico publicado en 2011

Suppression of metastasis of human pancreatic cancer to the liver by transportal injection of recombinant adenoviral NK4 in nude mice

artículo científico publicado en 2005

Suppression of the progress of disseminated pancreatic cancer cells by NK4 plasmid DNA released from cationized gelatin microspheres.

artículo científico publicado en 2004

Suppression of tumor metastasis by NK4 plasmid DNA released from cationized gelatin.

artículo científico publicado en 2004

Sustained-release prostacyclin analog ONO-1301 ameliorates tubulointerstitial alterations in a mouse obstructive nephropathy model

scientific article published on 14 March 2012

Targeted delivery of NK4 to multiple lung tumors by bone marrow-derived mesenchymal stem cells.

artículo científico publicado en 2007

Targeting the hepatocyte growth factor/Met pathway in cancer.

artículo científico publicado en 2017

The HGF/SF antagonist NK4 reverses fibroblast- and HGF-induced prostate tumor growth and angiogenesis in vivo.

artículo científico publicado en 2003

The novel phosphoinositide 3-kinase-mammalian target of rapamycin inhibitor, BEZ235, circumvents erlotinib resistance of epidermal growth factor receptor mutant lung cancer cells triggered by hepatocyte growth factor.

artículo científico publicado en 2013

The protective effect of hepatocyte growth factor against cell death in the hippocampus after transient forebrain ischemia is related to the improvement of apurinic/apyrimidinic endonuclease/redox factor-1 level and inhibition of NADPH oxidase activ

artículo científico publicado en 2006

Transient IGF-1R inhibition combined with osimertinib eradicates AXL-low expressing EGFR mutated lung cancer

artículo científico publicado en 2020

Transient PI3K inhibition induces apoptosis and overcomes HGF-mediated resistance to EGFR-TKIs in EGFR mutant lung cancer.

artículo científico publicado en 2011

Treatment of dilated cardiomyopathy with electroporation of hepatocyte growth factor gene into skeletal muscle.

artículo científico publicado en 2004

Tumor suppression effect using NK4, a molecule acting as an antagonist of HGF, on human gastric carcinomas.

artículo científico publicado en 2002

Tumor suppression induced by intratumor administration of adenovirus vector expressing NK4, a 4-kringle antagonist of hepatocyte growth factor, and naive dendritic cells.

artículo científico publicado en 2002

Up-regulation of integrin beta3 in radioresistant pancreatic cancer impairs adenovirus-mediated gene therapy.

artículo científico publicado en 2009

hTERT-promoter-dependent oncolytic adenovirus enhances the transduction and therapeutic efficacy of replication-defective adenovirus vectors in pancreatic cancer cells.

artículo científico publicado en 2009

mTOR inhibitors control the growth of EGFR mutant lung cancer even after acquiring resistance by HGF.

artículo científico publicado en 2013

α-Lipoic acid-induced inhibition of proliferation and met phosphorylation in human non-small cell lung cancer cells ⬇️

artículo científico publicado el 16 de marzo de 2013

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