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Lista de obras de T Hyötyläinen

42.3 METABOLOMICS APPROACHES TO STUDY METABOLIC CO-MORBIDITIES IN PSYCHOTIC DISORDERS.

artículo científico publicado en 2018

4β-Hydroxycholesterol Signals From the Liver to Regulate Peripheral Cholesterol Transporters

scientific article published on 27 March 2020

A Healthy Nordic Diet Alters the Plasma Lipidomic Profile in Adults with Features of Metabolic Syndrome in a Multicenter Randomized Dietary Intervention

artículo científico publicado en 2016

A computational framework to integrate high-throughput ‘-omics’ datasets for the identification of potential mechanistic links

A longitudinal plasma lipidomics dataset from children who developed islet autoimmunity and type 1 diabetes

artículo científico publicado en 2018

Age- and islet autoimmunity-associated differences in amino acid and lipid metabolites in children at risk for type 1 diabetes

artículo científico publicado en 2011

An Overview of Metabolomics Data Analysis: Current Tools and Future Perspectives

An environmentally relevant mixture of polychlorinated biphenyls (PCBs) and polybrominated diphenylethers (PBDEs) disrupts mitochondrial function, lipid metabolism and neurotransmission in the brain of exposed zebrafish and their unexposed F2 offspr

scientific article published on 01 September 2020

Analysis of particulate polycyclic aromatic hydrocarbons by on-line coupled supercritical fluid extraction–liquid chromatography–gas chromatography–mass spectrometry

article

Analysis of pesticides in red wines by on-line coupled reversed-phase liquid chromatography-gas chromatography with vaporiser/precolumn solvent split/gas discharge interface

artículo científico publicado en 1998

Analysis of phenols in pyrolysis oils by gel permeation chromatography and multidimensional liquid chromatography

scientific article published on 01 October 2000

Analysis of polycyclic aromatic hydrocarbons in soil and sediment with on-line coupled pressurised hot water extraction, hollow fibre microporous membrane liquid-liquid extraction and gas chromatography

scientific article published on 01 May 2003

Analytical Lipidomics in Metabolic and Clinical Research

artículo científico publicado en 2015

Analytical Methodologies Utilized in The Search for Chronic Disease Biomarkers

artículo científico publicado el 1 de mayo de 2010

Analytical challenges in human exposome analysis with focus on environmental analysis combined with metabolomics

artículo científico publicado en 2021

Approaches for on-line coupling of extraction and chromatography

artículo científico publicado en 2004

Association Between Circulating Lipids and Future Weight Gain in Individuals With an At-Risk Mental State and in First-Episode Psychosis

artículo científico publicado en 2020

Association of lipidome remodeling in the adipocyte membrane with acquired obesity in humans

artículo científico publicado en 2011

Bioanalytical techniques in nontargeted clinical lipidomics

artículo científico publicado en 2016

Ceramides in the pathophysiology of the anterior segment of the eye.

artículo científico

Characterisation of Stevia rebaudiana by comprehensive two-dimensional liquid chromatography time-of-flight mass spectrometry

scientific article published on 25 September 2006

Characterisation of organic compounds in aerosol particles from a Finnish forest by on-line coupled supercritical fluid extraction-liquid chromatography-gas chromatography-mass spectrometry

artículo científico publicado en 2004

Characterising metabolically healthy obesity in weight-discordant monozygotic twins

artículo científico publicado en 2013

Characterization of cerebrospinal fluid by comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry.

artículo científico publicado en 2013

Characterization of microbial metabolism of Syrah grape products in an in vitro colon model using targeted and non-targeted analytical approaches

artículo científico publicado en 2012

Characterization of organic compounds in aerosol particles from a coniferous forest by GC-MS.

artículo científico publicado en 2006

Chromatographic lipid profiling of stress-exposed cells

artículo científico publicado en 2012

Circulating metabolites in progression to islet autoimmunity and type 1 diabetes

artículo científico publicado en 2019

Circulating triacylglycerol signatures and insulin sensitivity in NAFLD associated with the E167K variant in TM6SF2

Circulating triacylglycerol signatures in nonalcoholic fatty liver disease associated with the I148M variant in PNPLA3 and with obesity

artículo científico publicado en 2013

Comparison of GC-MS and LC-MS methods for the analysis of antioxidant phenolic acids in herbs

artículo científico publicado en 2007

Comparison of different trapping methods for pressurised hot water extraction

scientific article published on 01 January 2004

Comparison of separation power of ultra performance liquid chromatography and comprehensive two-dimensional liquid chromatography in the separation of phenolic compounds in beverages

artículo científico publicado en 2008

Comprehensive Two-Dimensional Field-Flow Fractionation-Liquid Chromatography in the Analysis of Large Molecules

artículo científico publicado en 2007

Comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry in the identification of organic compounds in atmospheric aerosols from coniferous forest

scientific article published on 19 June 2006

Comprehensive two-dimensional gas chromatography in the analysis of dietary fatty acids

artículo científico publicado en 2004

Comprehensive two-dimensional gas chromatography in the analysis of urban aerosols.

artículo científico publicado en 2003

Comprehensive two-dimensional liquid chromatography coupled with mass spectrometry

artículo científico publicado en 2008

Comprehensive two-dimensional liquid chromatography in analysis of Lamiaceae herbs: characterisation and quantification of antioxidant phenolic acids

scientific article published on 31 January 2007

Comprehensive two-dimensional liquid chromatography in the analysis of antioxidant phenolic compounds in wines and juices

artículo científico publicado en 2008

Comprehensive two-dimensional liquid chromatography-time-of-flight mass spectrometry in the analysis of acidic compounds in atmospheric aerosols.

artículo científico publicado en 2006

Cord serum lipidome in prediction of islet autoimmunity and type 1 diabetes

artículo científico publicado en 2013

Cord-Blood Lipidome in Progression to Islet Autoimmunity and Type 1 Diabetes

scientific article published on 21 January 2019

Critical evaluation of sample pretreatment techniques

artículo científico publicado en 2009

Data analysis programs for comprehensive two-dimensional chromatography

artículo científico publicado en 2008

Data analysis tool for comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry

artículo científico publicado en 2011

Decreased cord-blood phospholipids in young age-at-onset type 1 diabetes

scientific article published on 08 August 2013

Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease

scientific article published on 01 May 2019

Determination of morphine analogues, caffeine and amphetamine in biological fluids by capillary electrophoresis with the marker technique

artículo científico publicado en 1996

Determination of organic acids in aerosol particles from a coniferous forest by liquid chromatography-mass spectrometry

artículo científico publicado en 2005

Determination of organic compounds from wood combustion aerosol nanoparticles by different gas chromatographic systems and by aerosol mass spectrometry

article

Drug metabolome of the simvastatin formed by human intestinal microbiota in vitro

artículo científico publicado en 2010

Dynamics of Plasma Lipidome in Progression to Islet Autoimmunity and Type 1 Diabetes - Type 1 Diabetes Prediction and Prevention Study (DIPP)

scientific article published on 13 July 2018

Dysregulated Lipid Metabolism Precedes Onset of Psychosis

scientific article published on 25 July 2020

Early-life exposure to perfluorinated alkyl substances modulates lipid metabolism in progression to celiac disease

artículo científico publicado en 2020

Effect of extraction vessel geometry and flow homogeneity on recoveries of polycyclic aromatic hydrocarbons in pressurised hot water extraction

scientific article published on 11 July 2003

Effect of perfluorooctanesulfonic acid (PFOS) on the liver lipid metabolism of the developing chicken embryo

artículo científico publicado en 2018

Effects of a Lacto-Ovo-Vegetarian Diet on the Plasma Lipidome and Its Association with Atherosclerotic Burden in Patients with Coronary Artery Disease-A Randomized, Open-Label, Cross-over Study

artículo científico publicado en 2020

Erratum to: Methods for characterization of organic compounds in atmospheric aerosol particles

artículo científico publicado en 2015

Exome sequencing identifies mitochondrial alanyl-tRNA synthetase mutations in infantile mitochondrial cardiomyopathy

artículo científico publicado en 2011

Extremely high electric field strengths in non-aqueous capillary electrophoresis

artículo científico publicado en 2001

Fish oil supplementation alters the plasma lipidomic profile and increases long-chain PUFAs of phospholipids and triglycerides in healthy subjects

artículo científico publicado en 2012

Genome-scale study reveals reduced metabolic adaptability in patients with non-alcoholic fatty liver disease

artículo científico publicado en 2016

Genomic, Transcriptomic, and Lipidomic Profiling Highlights the Role of Inflammation in Individuals With Low High-density Lipoprotein Cholesterol

Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist

artículo científico publicado en 2013

Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950-Metabolites in Frozen Human Plasma.

artículo científico publicado en 2017

Hepatic ceramides dissociate steatosis and insulin resistance in patients with non-alcoholic fatty liver disease.

artículo científico publicado en 2016

High-dose simvastatin exhibits enhanced lipid-lowering effects relative to simvastatin/ezetimibe combination therapy

artículo científico publicado en 2014

Human PNPLA3-I148M variant increases hepatic retention of polyunsaturated fatty acids

artículo científico publicado en 2019

Human Serum Metabolites Associate With Severity and Patient Outcomes in Traumatic Brain Injury

scientific article published on 15 July 2016

Human gut microbes impact host serum metabolome and insulin sensitivity

artículo científico publicado en 2016

Hydroxysteroid 17-β dehydrogenase 13 variant increases phospholipids and protects against fibrosis in nonalcoholic fatty liver disease

scientific article published on 12 March 2020

Hyperosmolarity-induced lipid droplet formation depends on ceramide production by neutral sphingomyelinase 2.

artículo científico publicado en 2012

Identification of a plasma signature of psychotic disorder in children and adolescents from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort.

artículo científico publicado en 2017

Identification of metabolic profiles associated with human exposure to perfluoroalkyl substances

artículo científico publicado en 2018

Imbalance of plasma amino acids, metabolites and lipids in patients with lysinuric protein intolerance (LPI).

artículo científico publicado en 2016

Impaired hepatic lipid synthesis from polyunsaturated fatty acids in TM6SF2 E167K variant carriers with NAFLD.

artículo científico publicado en 2017

Integrated Lipidomics and Proteomics Point to Early Blood-Based Changes in Childhood Preceding Later Development of Psychotic Experiences: Evidence From the Avon Longitudinal Study of Parents and Children

scientific article published on 30 January 2019

Integration of non-target metabolomics and sensory analysis unravels vegetable plant metabolite signatures associated with sensory quality: A case study using dill (Anethum graveolens)

artículo científico publicado en 2020

Integrative Analysis of Circulating Metabolite Profiles and Magnetic Resonance Imaging Metrics in Patients with Traumatic Brain Injury

scientific article published on 19 February 2020

Isoenergetic diets differing in their n-3 fatty acid and polyphenol content reflect different plasma and HDL-fraction lipidomic profiles in subjects at high cardiovascular risk

artículo científico publicado en 2014

Links between central CB1-receptor availability and peripheral endocannabinoids in patients with first episode psychosis

scientific article published on 26 August 2020

Lipidome as a predictive tool in progression to type 2 diabetes in Finnish men.

artículo científico publicado en 2017

Lipidomics in biomedical research-practical considerations

artículo científico publicado en 2017

Lipidomics in nutrition and food research.

artículo científico

Liquid Chromatography-Mass Spectrometry (LC-MS)-Based Lipidomics for Studies of Body Fluids and Tissues

scientific article published on 01 January 2011

Longitudinal plasma metabolic profiles, infant feeding, and islet autoimmunity in the MIDIA study

artículo científico publicado en 2016

MARC1 variant rs2642438 increases hepatic phosphatidylcholines and decreases severity of non-alcoholic fatty liver disease in humans

artículo científico publicado en 2020

MS-Based Lipidomics

Metabolic Signatures of the Exposome-Quantifying the Impact of Exposure to Environmental Chemicals on Human Health

artículo científico publicado en 2020

Metabolic alterations in immune cells associate with progression to type 1 diabetes

artículo científico publicado en 2020

Metabolome and fecal microbiota in monozygotic twin pairs discordant for weight: a Big Mac challenge

artículo científico publicado en 2014

Metabolome in schizophrenia and other psychotic disorders: a general population-based study

artículo científico publicado en 2011

Metabolomic analysis of polar metabolites in lipoprotein fractions identifies lipoprotein-specific metabolic profiles and their association with insulin resistance

article

Metabolomics Profiling As a Diagnostic Tool in Severe Traumatic Brain Injury.

artículo científico publicado en 2017

Methods for characterization of organic compounds in atmospheric aerosol particles.

artículo científico

Modified semi-rotating cryogenic modulator for comprehensive two-dimensional gas chromatography

artículo científico publicado en 2008

Modulator design for comprehensive two-dimensional gas chromatography: quantitative analysis of polyaromatic hydrocarbons and polychlorinated biphenyls

scientific article published on 01 September 2002

Mondo/ChREBP-Mlx-regulated transcriptional network is essential for dietary sugar tolerance in Drosophila

artículo científico publicado en 2013

Monounsaturated fatty acids in serum triacylglycerols are associated with response to neoadjuvant chemotherapy in breast cancer patients

artículo científico publicado en 2013

Multi- and transgenerational effects following early-life exposure of zebrafish to permethrin and coumarin 47: Impact on growth, fertility, behavior and lipid metabolism

scientific article published on 23 September 2020

Nonaqueous capillary electrophoresis with alcoholic background electrolytes: separation efficiency under high electrical field strengths

artículo científico publicado en 2002

Noninvasive Detection of Nonalcoholic Steatohepatitis Using Clinical Markers and Circulating Levels of Lipids and Metabolites

artículo científico publicado en 2016

Novel methodologies in metabolic profiling with a focus on molecular diagnostic applications

artículo científico publicado el 1 de junio de 2012

Novel theranostic opportunities offered by characterization of altered membrane lipid metabolism in breast cancer progression

artículo científico publicado en 2011

Novel, dynamic on-line analytical separation system for dissolution of drugs from poly(lactic acid) nanoparticles

artículo científico publicado en 2009

On-line coupled dynamic sonication-assisted extraction-liquid chromatography for the determination of phenolic acids in Lamiaceae herbs.

artículo científico publicado en 2008

On-line coupled liquid chromatography-gas chromatography

artículo científico publicado en 2003

On-line coupling of extraction with gas chromatography

artículo científico publicado en 2007

On-line coupling of microporous membrane liquid-liquid extraction and gas chromatography in the analysis of organic pollutants in water

artículo científico publicado en 2004

Optimizing the lipidomics workflow for clinical studies--practical considerations.

artículo científico

Particle Size Distribution and Gas-Particle Partition of Polycyclic Aromatic Hydrocarbons in Helsinki Urban Area

Patient-Specific Induced Pluripotent Stem Cell-Derived RPE Cells: Understanding the Pathogenesis of Retinopathy in Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency

artículo científico publicado en 2015

Persistent Alterations in Plasma Lipid Profiles Before Introduction of Gluten in the Diet Associated With Progression to Celiac Disease

scientific article published on 01 May 2019

Persistent alterations in plasma lipid profiles prior to introduction of gluten in the diet associate with progression to celiac disease

Perspectives of on-line coupled liquid chromatography-gas chromatography

scientific article published on 21 January 2004

Phenolic metabolites as compliance biomarker for polyphenol intake in a randomized controlled human intervention

Phospholipids and insulin resistance in psychosis: a lipidomics study of twin pairs discordant for schizophrenia

artículo científico publicado en 2012

Platform for systems medicine research and diagnostic applications in psychotic disorders-The METSY project

artículo científico publicado en 2017

Poster #170 PROLINE AND SCHIZOPHRENIA: A POPULATION-BASED STUDY

Prediction of non-alcoholic fatty-liver disease and liver fat content by serum molecular lipids

artículo científico publicado en 2013

Prenatal exposure to perfluoroalkyl substances modulates neonatal serum phospholipids, increasing risk of type 1 diabetes

artículo científico publicado en 2020

Pressurised hot water extraction coupled on-line with liquid chromatography-gas chromatography for the determination of brominated flame retardants in sediment samples

scientific article published on 01 January 2002

Principles, developments and applications of on-line coupling of extraction with chromatography

artículo científico publicado en 2007

Professor Marja-Liisa Riekkola's 60th birthday.

artículo científico publicado en 2013

Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses

artículo científico publicado en 2016

Quantitative aspects in comprehensive two-dimensional gas chromatography

artículo científico publicado en 2007

Quantitative profiling of bile acids in blood, adipose tissue, intestine, and gall bladder samples using ultra high performance liquid chromatography-tandem mass spectrometry

Rapid quantitative analysis of carnitine and acylcarnitines by ultra-high performance–hydrophilic interaction liquid chromatography–tandem mass spectrometry

article

Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress

artículo científico publicado en 2012

Sample preparation for chromatographic analysis of environmental samples

scientific article published on 01 January 2010

Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars

artículo científico publicado en 2018

Semi-rotating cryogenic modulator for comprehensive two-dimensional gas chromatography

artículo científico publicado en 2003

Separation of nucleobases, nucleosides, and nucleotides using two zwitterionic silica-based monolithic capillary columns coupled with tandem mass spectrometry.

artículo científico publicado en 2014

Serum Lipid and Serum Metabolite Components in relation to anthropometric parameters in EPIC-Potsdam participants

artículo científico publicado en 2015

Serum Metabolites Associated with Computed Tomography Findings after Traumatic Brain Injury

artículo científico publicado en 2018

Serum metabolite profile associates with the development of metabolic co-morbidities in first-episode psychosis

artículo científico publicado en 2016

Serum untargeted lipidomic profiling reveals dysfunction of phospholipid metabolism in subclinical coronary artery disease.

artículo científico publicado en 2019

Serum, plasma and erythrocyte membrane lipidomes in infants fed formula supplemented with bovine milk fat globule membranes

artículo científico publicado en 2018

Simple calibration procedure for comprehensive two-dimensional gas chromatography

artículo científico publicado en 2008

Simultaneous determination of perfluoroalkyl substances and bile acids in human serum using ultra-high-performance liquid chromatography-tandem mass spectrometry

artículo científico publicado en 2019

Solid-phase extraction of organic compounds in atmospheric aerosol particles collected with the particle-into-liquid sampler and analysis by liquid chromatography-mass spectrometry

artículo científico publicado en 2010

Solid-phase extraction or liquid chromatography coupled on-line with gas chromatography in the analysis of biological samples

artículo científico publicado en 2005

Sorbent- and liquid-phase microextraction techniques and membrane-assisted extraction in combination with gas chromatographic analysis: A review

artículo científico publicado en 2008

Spatial distribution of glycerophospholipids in the ocular lens

artículo científico publicado en 2011

Stability of polycyclic aromatic hydrocarbons in pressurised hot water

scientific article published on 01 February 2003

Steroid and steroid glucuronide profiles in urine during pregnancy determined by liquid chromatography–electrospray ionization-tandem mass spectrometry

artículo científico publicado en 2013

Synergy between 15-lipoxygenase and secreted PLA2 promotes inflammation by formation of TLR4 agonists from extracellular vesicles

scientific article published on 24 September 2020

Systems biology approaches to study lipidomes in health and disease

artículo científico publicado en 2020

Systems biology strategies to study lipidomes in health and disease.

artículo científico

Targeted Clinical Metabolite Profiling Platform for the Stratification of Diabetic Patients

artículo científico publicado en 2019

Targeted Serum Metabolite Profiling Identifies Metabolic Signatures in Patients with Alzheimer's Disease, Normal Pressure Hydrocephalus and Brain Tumor

artículo científico publicado en 2017

The Dynamics of the Human Infant Gut Microbiome in Development and in Progression toward Type 1 Diabetes

scholarly article published by Päivi Pöhö in 2016

The MBOAT7 variant rs641738 alters hepatic phosphatidylinositols and increases severity of non-alcoholic fatty liver disease in humans.

artículo científico publicado en 2016

The Metabolome in Finnish Carriers of the MYBPC3-Q1061X Mutation for Hypertrophic Cardiomyopathy

artículo científico publicado en 2015

The PNPLA3-I148M variant increases polyunsaturated triglycerides in human adipose tissue

scientific article published on 09 May 2020

The dynamics of the human infant gut microbiome in development and in progression toward type 1 diabetes

artículo científico publicado en 2015

The effect of atorvastatin treatment on serum oxysterol concentrations and cytochrome P450 3A4 activity.

artículo científico publicado en 2015

The gut microbiota modulates glycaemic control and serum metabolite profiles in non-obese diabetic mice

artículo científico publicado en 2014

The influence of sample collection methodology and sample preprocessing on the blood metabolic profile

artículo científico publicado en 2015

Toxicology and Environmental Characteristics of emerging pollutants

scientific article published on 12 June 2019