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Lista de obras de Clemens Scheufler

Applications of Biophysics in High-Throughput Screening Hit Validation.

artículo científico publicado en 2014

Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy

artículo científico publicado en 2017

Detecting S-adenosyl-L-methionine-induced conformational change of a histone methyltransferase using a homogeneous time-resolved fluorescence-based binding assay.

artículo científico publicado en 2012

Discovery of Novel Dot1L Inhibitors through a Structure-Based Fragmentation Approach

artículo científico publicado en 2016

Discovery of Potent, Selective, and Structurally Novel Dot1L Inhibitors by a Fragment Linking Approach.

artículo científico publicado en 2017

Discovery of WRN inhibitor HRO761 with synthetic lethality in MSI cancers

artículo científico publicado en 2024

Identification of FAM181A and FAM181B as new interactors with the TEAD transcription factors

scientific article published on 20 November 2019

Identification of a 5-[3-phenyl-(2-cyclic-ether)-methylether]-4-aminopyrrolo[2,3-d]pyrimidine series of IGF-1R inhibitors

artículo científico publicado en 2016

Identification of a Novel Allosteric Inhibitory Site on Tryptophan Hydroxylase 1 Enabling Unprecedented Selectivity Over all Related Hydroxylases

artículo científico publicado en 2017

Imidazo[1,2-a]pyridin-6-yl-benzamide analogs as potent RAF inhibitors.

artículo científico publicado en 2017

In vivo and in vitro SAR of tetracyclic MAPKAP-K2 (MK2) inhibitors. Part II

artículo científico publicado en 2010

Large scale meta-analysis of fragment-based screening campaigns: privileged fragments and complementary technologies

artículo científico publicado en 2015

New Potent DOT1L Inhibitors for in Vivo Evaluation in Mouse

scientific article published on 04 December 2019

Optimization of a Fragment-Based Screening Hit toward Potent DOT1L Inhibitors Interacting in an Induced Binding Pocket

artículo científico publicado en 2016

Pyrrolo-pyrimidones: a novel class of MK2 inhibitors with potent cellular activity.

artículo científico publicado en 2008

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