Lista de obras - Jasmin Mecinovic - Dominio Público Uruguay

2-Oxoglutarate analogue inhibitors of prolyl hydroxylase domain 2.

artículo científico publicado en 2009

2-Oxoglutarate regulates binding of hydroxylated hypoxia-inducible factor to prolyl hydroxylase domain 2.

artículo científico publicado en 2018

A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene

artículo científico publicado en 2009

Alendronate-Functionalized Poly(2-oxazoline)s with Tunable Affinity for Calcium Cations

artículo científico publicado en 2019

Application of a proteolysis/mass spectrometry method for investigating the effects of inhibitors on hydroxylase structure.

artículo científico publicado en 2009

Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor

artículo científico publicado en 2007

Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles.

artículo científico publicado en 2010

Catalytic Staudinger Reduction at Room Temperature

scientific article published on 09 May 2019

Catalytic transport of molecular cargo using diffusive binding along a polymer track

artículo científico publicado en 2019

Cation-π Interactions Contribute to Substrate Recognition in γ-Butyrobetaine Hydroxylase Catalysis

artículo científico publicado en 2015

Chemical basis for the recognition of trimethyllysine by epigenetic reader proteins.

artículo científico publicado en 2015

Comparison of Molecular Recognition of Trimethyllysine and Trimethylthialysine by Epigenetic Reader Proteins

artículo científico publicado en 2020

Crotonase Catalysis Enables Flexible Production of Functionalized Prolines and Carbapenams

article

Dual-action inhibitors of HIF prolyl hydroxylases that induce binding of a second iron ion.

artículo científico publicado en 2012

Epidithiodiketopiperazines block the interaction between hypoxia-inducible factor-1alpha (HIF-1alpha) and p300 by a zinc ejection mechanism

scientific article published on 09 July 2009

Evidence That Trimethyllysine Hydroxylase Catalyzes the Formation of (2S,3S)-3-Hydroxy-Nε-trimethyllysine.

artículo científico publicado en 2017

Evidence for a stereoelectronic effect in human oxygen sensing.

artículo científico publicado en 2009

Evidence that the catenane form of CS2 hydrolase is not an artefact.

artículo científico publicado en 2013

Evidence that thienamycin biosynthesis proceeds via C-5 epimerization: ThnE catalyzes the formation of (2S,5S)-trans-carboxymethylproline.

artículo científico publicado en 2009

Examining sterically demanding lysine analogs for histone lysine methyltransferase catalysis

artículo científico publicado en 2020

Exploring the Histone Acylome through Incorporation of γ-Thialysine on Histone Tails

scientific article published on 27 February 2020

Fluorinated trimethyllysine as a 19F NMR probe for trimethyllysine hydroxylase catalysis.

artículo científico publicado en 2017

Hydroxylamine as an oxygen nucleophile: substitution of sulfonamide by a hydroxyl group in benzothiazole-2-sulfonamides.

artículo científico publicado en 2013

Importance of the main chain of lysine for histone lysine methyltransferase catalysis

scientific article published on 01 June 2019

Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II).

artículo científico publicado en 2018

Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2,4-dicarboxylates

artículo científico publicado en 2010

Inhibition of the histone lysine demethylase JMJD2A by ejection of structural Zn(II).

artículo científico publicado en 2009

Installation of Trimethyllysine Analogs on Intact Histones via Cysteine Alkylation

scientific article published on 07 March 2019

Investigating d-lysine stereochemistry for epigenetic methylation, demethylation and recognition.

artículo científico publicado en 2017

Investigating the active site of human trimethyllysine hydroxylase

scientific article published on 10 April 2019

LHP1 Interacts with ATRX through Plant-Specific Domains at Specific Loci Targeted by PRC2

article

Lysine Ethylation by Histone Lysine Methyltransferases

scientific article published on 24 October 2019

Lysine Possesses the Optimal Chain Length for Histone Lysine Methyltransferase Catalysis.

artículo científico publicado en 2017

Mechanistic Insight into the Catalytic Staudinger Ligation

artículo científico publicado en 2019

Methylation of geometrically constrained lysine analogues by histone lysine methyltransferases

artículo científico publicado en 2020

Multicolor Photoluminescence Including White-Light Emission by a Single Host-Guest Complex

artículo científico publicado en 2016

Natural supramolecular protein assemblies.

artículo científico publicado en 2015

Novel SAR for quinazoline inhibitors of EHMT1 and EHMT2

artículo científico publicado en 2019

Poly(methylhydrosiloxane) as a green reducing agent in organophosphorus-catalysed amide bond formation

artículo científico publicado en 2017

Probing Halogen-π versus CH-π Interactions in Molecular Balance

scientific article published on 29 September 2020

Probing Through-Space Polar-π Interactions in 2,6-Diarylphenols

scientific article published on 04 March 2019

Recognition of shorter and longer trimethyllysine analogues by epigenetic reader proteins

artículo científico publicado en 2018

Small-molecules that covalently react with a human prolyl hydroxylase – towards activity modulation and substrate capture

artículo científico publicado en 2019

Stabilization of 2,6-Diarylanilinum Cation by Through-Space Cation-π Interactions.

artículo científico publicado en 2017

Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases

artículo científico publicado en 2009

Structure-Activity Relationship Studies on (R)-PFI-2 Analogues as Inhibitors of Histone Lysine Methyltransferase SETD7

artículo científico publicado en 2018

Substrate scope for trimethyllysine hydroxylase catalysis

artículo científico publicado en 2016

The Role of Electrostatic Interactions in Binding of Histone H3K4me2/3 to the Sgf29 Tandem Tudor Domain.

artículo científico publicado en 2015

The effect of the length of histone H3K4me3 on recognition by reader proteins.

artículo científico publicado en 2013

Thermodynamic investigation of Z33-antibody interaction leads to selective purification of human antibodies

artículo científico publicado en 2014

Through-Space Polar-π Interactions in 2,6-Diarylthiophenols

scientific article published on 06 April 2020

Through-Space Polar-π Interactions in 2,6-Diarylthiophenols

artículo científico publicado en 2020

Transmission electron microscopy enables the reconstruction of the catenane and ring forms of CS2 hydrolase.

artículo científico publicado en 2014

Trimethyllysine: From Carnitine Biosynthesis to Epigenetics

artículo científico publicado en 2020

Triphenylphosphine-catalysed amide bond formation between carboxylic acids and amines

scientific article published on 22 April 2014

Use of mass spectrometry to probe the nucleophilicity of cysteinyl residues of prolyl hydroxylase domain 2.

artículo científico publicado en 2009

γ-Thialysine versus Lysine: An Insight into the Epigenetic Methylation of Histones

artículo científico publicado en 2019

Lista de obras de Jasmin Mecinovic

2-Oxoglutarate analogue inhibitors of prolyl hydroxylase domain 2.

2-Oxoglutarate regulates binding of hydroxylated hypoxia-inducible factor to prolyl hydroxylase domain 2.

A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene

Alendronate-Functionalized Poly(2-oxazoline)s with Tunable Affinity for Calcium Cations

Application of a proteolysis/mass spectrometry method for investigating the effects of inhibitors on hydroxylase structure.

Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor

Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles.

Catalytic Staudinger Reduction at Room Temperature

Catalytic transport of molecular cargo using diffusive binding along a polymer track

Cation-π Interactions Contribute to Substrate Recognition in γ-Butyrobetaine Hydroxylase Catalysis

Chemical basis for the recognition of trimethyllysine by epigenetic reader proteins.

Comparison of Molecular Recognition of Trimethyllysine and Trimethylthialysine by Epigenetic Reader Proteins

Crotonase Catalysis Enables Flexible Production of Functionalized Prolines and Carbapenams

Dual-action inhibitors of HIF prolyl hydroxylases that induce binding of a second iron ion.

Epidithiodiketopiperazines block the interaction between hypoxia-inducible factor-1alpha (HIF-1alpha) and p300 by a zinc ejection mechanism

Evidence That Trimethyllysine Hydroxylase Catalyzes the Formation of (2S,3S)-3-Hydroxy-Nε-trimethyllysine.

Evidence for a stereoelectronic effect in human oxygen sensing.

Evidence that the catenane form of CS2 hydrolase is not an artefact.

Evidence that thienamycin biosynthesis proceeds via C-5 epimerization: ThnE catalyzes the formation of (2S,5S)-trans-carboxymethylproline.

Examining sterically demanding lysine analogs for histone lysine methyltransferase catalysis

Exploring the Histone Acylome through Incorporation of γ-Thialysine on Histone Tails

Fluorinated trimethyllysine as a 19F NMR probe for trimethyllysine hydroxylase catalysis.

Hydroxylamine as an oxygen nucleophile: substitution of sulfonamide by a hydroxyl group in benzothiazole-2-sulfonamides.

Importance of the main chain of lysine for histone lysine methyltransferase catalysis

Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II).

Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2,4-dicarboxylates

Inhibition of the histone lysine demethylase JMJD2A by ejection of structural Zn(II).

Installation of Trimethyllysine Analogs on Intact Histones via Cysteine Alkylation

Investigating d-lysine stereochemistry for epigenetic methylation, demethylation and recognition.

Investigating the active site of human trimethyllysine hydroxylase

LHP1 Interacts with ATRX through Plant-Specific Domains at Specific Loci Targeted by PRC2

Lysine Ethylation by Histone Lysine Methyltransferases

Lysine Possesses the Optimal Chain Length for Histone Lysine Methyltransferase Catalysis.

Mechanistic Insight into the Catalytic Staudinger Ligation

Methylation of geometrically constrained lysine analogues by histone lysine methyltransferases

Multicolor Photoluminescence Including White-Light Emission by a Single Host-Guest Complex

Natural supramolecular protein assemblies.

Novel SAR for quinazoline inhibitors of EHMT1 and EHMT2

Poly(methylhydrosiloxane) as a green reducing agent in organophosphorus-catalysed amide bond formation

Probing Halogen-π versus CH-π Interactions in Molecular Balance

Probing Through-Space Polar-π Interactions in 2,6-Diarylphenols

Recognition of shorter and longer trimethyllysine analogues by epigenetic reader proteins

Small-molecules that covalently react with a human prolyl hydroxylase – towards activity modulation and substrate capture

Stabilization of 2,6-Diarylanilinum Cation by Through-Space Cation-π Interactions.

Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases

Structure-Activity Relationship Studies on (R)-PFI-2 Analogues as Inhibitors of Histone Lysine Methyltransferase SETD7

Substrate scope for trimethyllysine hydroxylase catalysis

The Role of Electrostatic Interactions in Binding of Histone H3K4me2/3 to the Sgf29 Tandem Tudor Domain.

The effect of the length of histone H3K4me3 on recognition by reader proteins.

Thermodynamic investigation of Z33-antibody interaction leads to selective purification of human antibodies

Through-Space Polar-π Interactions in 2,6-Diarylthiophenols

Through-Space Polar-π Interactions in 2,6-Diarylthiophenols

Transmission electron microscopy enables the reconstruction of the catenane and ring forms of CS2 hydrolase.

Trimethyllysine: From Carnitine Biosynthesis to Epigenetics

Triphenylphosphine-catalysed amide bond formation between carboxylic acids and amines

Use of mass spectrometry to probe the nucleophilicity of cysteinyl residues of prolyl hydroxylase domain 2.

γ-Thialysine versus Lysine: An Insight into the Epigenetic Methylation of Histones