Lista de obras - Yves Mechulam - Dominio Público Uruguay

A Minimal Sequence for Left-Handed G-Quadruplex Formation

artículo científico publicado en 2019

A unique conformation of the anticodon stem-loop is associated with the capacity of tRNAfMet to initiate protein synthesis

artículo científico publicado en 2008

Adaptive landscape flattening allows the design of both enzyme: Substrate binding and catalytic power

scientific article published on 09 January 2020

Capturing the mutational landscape of the beta-lactamase TEM-1.

artículo científico publicado en 2013

Cdc123, a Cell Cycle Regulator Needed for eIF2 Assembly, Is an ATP-Grasp Protein with Unique Features

artículo científico publicado en 2015

Cryo-EM study of an archaeal 30S initiation complex gives insights into evolution of translation initiation

artículo científico publicado en 2020

Cryo-EM study of start codon selection during archaeal translation initiation

artículo científico publicado en 2016

Crystal structure at 1.2Aresolution and active site mapping of Escherichia coli peptidyl-tRNA hydrolase ⬇️

artículo científico publicado el 1 de agosto de 1997

Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights species-specific features

artículo científico publicado en 1999

Crystal structure of methionyl-tRNAfMet transformylase complexed with the initiator formyl-methionyl-tRNAfMet.

artículo científico publicado en 1998

Crystallization and preliminary X-ray analysis of Escherichia coli methionyl-tRNAMet(f) formyltransferase complexed with formyl-methionyl-tRNAMet(f)

artículo científico publicado en 1999

Crystallization and preliminary X-ray analysis of Escherichia coli peptidyl-tRNA hydrolase.

artículo científico publicado en 1997

Discovery of Escherichia coli methionyl-tRNA synthetase mutants for efficient labeling of proteins with azidonorleucine in vivo

scientific article published on 17 August 2009

Eukaryotic and archaeal translation initiation factor 2: a heterotrimeric tRNA carrier.

scientific article published on January 2010

Fast purification of a functional elongator tRNAmetexpressed from a synthetic genein vivo ⬇️

artículo científico publicado el 25 de agosto de 1988

General structure/function properties of microbial methionyl-tRNA synthetases.

artículo científico publicado en 1997

Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2.

artículo científico publicado en 2015

Interplay of Methionine tRNAs with Translation Elongation Factor Tu and Translation Initiation Factor 2 inEscherichia coli

artículo científico publicado en 1996

Lysine 335, part of the KMSKS signature sequence, plays a crucial role in the amino acid activation catalysed by the methionyl-tRNA synthetase from Escherichia coli ⬇️

artículo científico publicado el 5 de febrero de 1991

Methionine as translation start signal: a review of the enzymes of the pathway in Escherichia coli.

artículo científico publicado en 1993

Methionyl-tRNA synthetase needs an intact and mobile 332KMSKS336 motif in catalysis of methionyl adenylate formation.

artículo científico publicado en 1994

Mitochondrial methionyl-tRNAfMet formyltransferase from Saccharomyces cerevisiae: gene disruption and tRNA substrate specificity.

artículo científico publicado en 2003

Protection-based assays to measure aminoacyl-tRNA binding to translation initiation factors

artículo científico publicado en 2007

Receptor site for the 5'-phosphate of elongator tRNAs governs substrate selection by peptidyl-tRNA hydrolase

artículo científico publicado en 1999

Recognition of different base tetrads by RHAU (DHX36): X-ray crystal structure of the G4 recognition motif bound to the 3'-end tetrad of a DNA G-quadruplex

artículo científico publicado en 2019

Role of aIF1 in Pyrococcus abyssi translation initiation

artículo científico publicado en 2018

Role of the 1-72 base pair in tRNAs for the activity of Escherichia coli peptidyl-tRNA hydrolase.

artículo científico publicado en 1993

Roles of yeast eIF2α and eIF2β subunits in the binding of the initiator methionyl-tRNA.

artículo científico publicado en 2012

Start Codon Recognition in Eukaryotic and Archaeal Translation Initiation: A Common Structural Core

scientific article published on 21 February 2019

Structural bases for 16 S rRNA methylation catalyzed by ArmA and RmtB methyltransferases

artículo científico publicado en 2009

Structural basis for partition of the cyclodipeptide synthases into two subfamilies.

artículo científico publicado en 2018

Structural basis for tRNA-dependent amidotransferase function.

artículo científico publicado en 2005

Structural basis of RNA-dependent recruitment of glutamine to the genetic code

artículo científico publicado en 2006

Structural basis of the interaction between cyclodipeptide synthases and aminoacylated tRNA substrates

artículo científico publicado en 2020

Structural switch of the gamma subunit in an archaeal aIF2 alpha gamma heterodimer.

artículo científico publicado en 2006

Structure of a left-handed DNA G-quadruplex

artículo científico publicado en 2015

Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states

artículo científico publicado en 2007

Structure of crystalline D-Tyr-tRNA(Tyr) deacylase. A representative of a new class of tRNA-dependent hydrolases

artículo científico publicado en 2001

Structure of the ternary initiation complex aIF2-GDPNP-methionylated initiator tRNA

artículo científico publicado en 2012

Structure-function relationships of the intact aIF2alpha subunit from the archaeon Pyrococcus abyssi

scientific article published on 01 June 2005

The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors.

artículo científico publicado en 2002

The many routes of bacterial transfer RNAs after aminoacylation.

artículo científico publicado en 2000

The structure of an E. coli tRNAfMet A1-U72 variant shows an unusual conformation of the A1-U72 base pair.

artículo científico publicado en 2017

The trimeric coiled-coil HSBP1 protein promotes WASH complex assembly at centrosomes

artículo científico publicado en 2018

Three-dimensional structure of methionyl-tRNA synthetase from Pyrococcus abyssi.

artículo científico publicado en 2004

Translation Initiation

artículo científico publicado en 2011

Unravelling the mechanism of non-ribosomal peptide synthesis by cyclodipeptide synthases

artículo científico publicado en 2014

tRNA binding properties of eukaryotic translation initiation factor 2 from Encephalitozoon cuniculi

artículo científico publicado en 2010

Lista de obras de Yves Mechulam

A Minimal Sequence for Left-Handed G-Quadruplex Formation

A unique conformation of the anticodon stem-loop is associated with the capacity of tRNAfMet to initiate protein synthesis

Adaptive landscape flattening allows the design of both enzyme: Substrate binding and catalytic power

Capturing the mutational landscape of the beta-lactamase TEM-1.

Cdc123, a Cell Cycle Regulator Needed for eIF2 Assembly, Is an ATP-Grasp Protein with Unique Features

Cryo-EM study of an archaeal 30S initiation complex gives insights into evolution of translation initiation

Cryo-EM study of start codon selection during archaeal translation initiation

Crystal structure at 1.2Aresolution and active site mapping of Escherichia coli peptidyl-tRNA hydrolase ⬇️

Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights species-specific features

Crystal structure of methionyl-tRNAfMet transformylase complexed with the initiator formyl-methionyl-tRNAfMet.

Crystallization and preliminary X-ray analysis of Escherichia coli methionyl-tRNAMet(f) formyltransferase complexed with formyl-methionyl-tRNAMet(f)

Crystallization and preliminary X-ray analysis of Escherichia coli peptidyl-tRNA hydrolase.

Discovery of Escherichia coli methionyl-tRNA synthetase mutants for efficient labeling of proteins with azidonorleucine in vivo

Eukaryotic and archaeal translation initiation factor 2: a heterotrimeric tRNA carrier.

Fast purification of a functional elongator tRNAmetexpressed from a synthetic genein vivo ⬇️

General structure/function properties of microbial methionyl-tRNA synthetases.

Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2.

Interplay of Methionine tRNAs with Translation Elongation Factor Tu and Translation Initiation Factor 2 inEscherichia coli

Lysine 335, part of the KMSKS signature sequence, plays a crucial role in the amino acid activation catalysed by the methionyl-tRNA synthetase from Escherichia coli ⬇️

Methionine as translation start signal: a review of the enzymes of the pathway in Escherichia coli.

Methionyl-tRNA synthetase needs an intact and mobile 332KMSKS336 motif in catalysis of methionyl adenylate formation.

Mitochondrial methionyl-tRNAfMet formyltransferase from Saccharomyces cerevisiae: gene disruption and tRNA substrate specificity.

Protection-based assays to measure aminoacyl-tRNA binding to translation initiation factors

Receptor site for the 5'-phosphate of elongator tRNAs governs substrate selection by peptidyl-tRNA hydrolase

Recognition of different base tetrads by RHAU (DHX36): X-ray crystal structure of the G4 recognition motif bound to the 3'-end tetrad of a DNA G-quadruplex

Role of aIF1 in Pyrococcus abyssi translation initiation

Role of the 1-72 base pair in tRNAs for the activity of Escherichia coli peptidyl-tRNA hydrolase.

Roles of yeast eIF2α and eIF2β subunits in the binding of the initiator methionyl-tRNA.

Start Codon Recognition in Eukaryotic and Archaeal Translation Initiation: A Common Structural Core

Structural bases for 16 S rRNA methylation catalyzed by ArmA and RmtB methyltransferases

Structural basis for partition of the cyclodipeptide synthases into two subfamilies.

Structural basis for tRNA-dependent amidotransferase function.

Structural basis of RNA-dependent recruitment of glutamine to the genetic code

Structural basis of the interaction between cyclodipeptide synthases and aminoacylated tRNA substrates

Structural switch of the gamma subunit in an archaeal aIF2 alpha gamma heterodimer.

Structure of a left-handed DNA G-quadruplex

Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states

Structure of crystalline D-Tyr-tRNA(Tyr) deacylase. A representative of a new class of tRNA-dependent hydrolases

Structure of the ternary initiation complex aIF2-GDPNP-methionylated initiator tRNA

Structure-function relationships of the intact aIF2alpha subunit from the archaeon Pyrococcus abyssi

The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors.

The many routes of bacterial transfer RNAs after aminoacylation.

The structure of an E. coli tRNAfMet A1-U72 variant shows an unusual conformation of the A1-U72 base pair.

The trimeric coiled-coil HSBP1 protein promotes WASH complex assembly at centrosomes

Three-dimensional structure of methionyl-tRNA synthetase from Pyrococcus abyssi.

Translation Initiation

Unravelling the mechanism of non-ribosomal peptide synthesis by cyclodipeptide synthases

tRNA binding properties of eukaryotic translation initiation factor 2 from Encephalitozoon cuniculi