Filtros de búsqueda

Lista de obras de Charlotte Kilstrup-Nielsen

A Novel Mecp2 Knock-in Model Displays Similar Behavioral Traits But Distinct Molecular Features Compared to the Mecp2-Null Mouse Implying Precision Medicine for the Treatment of Rett Syndrome

scientific article published on 06 November 2018

A novel protein, Xenopus p20, influences the stability of MeCP2 through direct interaction.

artículo científico publicado en 2004

A novel transcript of cyclin-dependent kinase-like 5 (CDKL5) has an alternative C-terminus and is the predominant transcript in brain.

artículo científico publicado en 2011

Brain phosphorylation of MeCP2 at serine 164 is developmentally regulated and globally alters its chromatin association

artículo científico publicado en 2016

CDKL5 and Shootin1 Interact and Concur in Regulating Neuronal Polarization

artículo científico publicado en 2016

CDKL5 belongs to the same molecular pathway of MeCP2 and it is responsible for the early-onset seizure variant of Rett syndrome

artículo científico publicado en 2005

CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons.

artículo científico publicado en 2012

CDKL5 influences RNA splicing activity by its association to the nuclear speckle molecular machinery

artículo científico publicado en 2009

CDKL5 localizes at the centrosome and midbody and is required for faithful cell division

artículo científico publicado en 2017

Characterisation of CDKL5 Transcript Isoforms in Human and Mouse

artículo científico publicado en 2016

Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.

artículo científico publicado en 2015

Extrasynaptic N-Methyl-d-aspartate (NMDA) Receptor Stimulation Induces Cytoplasmic Translocation of the CDKL5 Kinase and Its Proteasomal Degradation ⬇️

artículo científico publicado el 5 de agosto de 2011

Functional consequences of mutations in CDKL5, an X-linked gene involved in infantile spasms and mental retardation

artículo científico publicado en 2006

Genetics and mechanisms of disease in Rett syndrome

article

MeCP2 Affects Skeletal Muscle Growth and Morphology through Non Cell-Autonomous Mechanisms

artículo científico publicado en 2015

MeCP2 Related Studies Benefit from the Use of CD1 as Genetic Background.

artículo científico publicado en 2016

MeCP2 post-translational modifications: a mechanism to control its involvement in synaptic plasticity and homeostasis?

artículo científico publicado en 2014

Methyl-CpG binding protein 2 (MeCP2) localizes at the centrosome and is required for proper mitotic spindle organization

scientific journal article

PBX1 nuclear export is regulated independently of PBX-MEINOX interaction by PKA phosphorylation of the PBC-B domain.

artículo científico publicado en 2003

Rescue of prepulse inhibition deficit and brain mitochondrial dysfunction by pharmacological stimulation of the central serotonin receptor 7 in a mouse model of CDKL5 Deficiency Disorder

article

Rett syndrome and the urge of novel approaches to study MeCP2 functions and mechanisms of action.

artículo científico

Synaptic synthesis, dephosphorylation, and degradation: a novel paradigm for an activity-dependent neuronal control of CDKL5

artículo científico publicado en 2015

The MeCP2/YY1 interaction regulates ANT1 expression at 4q35: novel hints for Rett syndrome pathogenesis.

artículo científico publicado en 2010

The antidepressant tianeptine reverts synaptic AMPA receptor defects caused by deficiency of CDKL5.

artículo científico publicado en 2018

The neurosteroid pregnenolone reverts microtubule derangement induced by the loss of a functional CDKL5-IQGAP1 complex

artículo científico publicado en 2017

What we know and would like to know about CDKL5 and its involvement in epileptic encephalopathy

artículo científico publicado en 2012

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda