Lista de obras - T Stankovic - Dominio Público Uruguay

A Hypomorphic PALB2 Allele Gives Rise to an Unusual Form of FA-N Associated with Lymphoid Tumour Development

artículo científico publicado en 2016

A multi-centre phase I trial of the PARP inhibitor olaparib in patients with relapsed chronic lymphocytic leukaemia, T-prolymphocytic leukaemia or mantle cell lymphoma

artículo científico publicado en 2017

A new minimal deleted region at 11q22.3 reveals the importance of interpretation of diminished FISH signals and the choice of probe for ATM deletion screening in chronic lymphocytic leukemia

scientific article published on 28 September 2011

A novel CDK inhibitor, CYC202 (R-roscovitine), overcomes the defect in p53-dependent apoptosis in B-CLL by down-regulation of genes involved in transcription regulation and survival.

artículo científico publicado en 2005

A novel functional assay using etoposide plus nutlin-3a detects and distinguishes between ATM and TP53 mutations in CLL.

artículo científico publicado en 2008

A physical map across chromosome 11q22-q23 containing the major locus for ataxia telangiectasia.

artículo científico publicado en 1994

A regulatory role for NBS1 in strand-specific mutagenesis during somatic hypermutation

artículo científico publicado en 2008

ATM mutation rather than BIRC3 deletion and/or mutation predicts reduced survival in 11q-deleted chronic lymphocytic leukemia: data from the UK LRF CLL4 trial.

artículo científico publicado en 2014

ATM mutations in sporadic lymphoid tumours.

artículo científico publicado en 2002

ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

scientific article published in Nature Communications

ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

article

ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53- or ATM-defective chronic lymphocytic leukemia cells

artículo científico publicado en 2015

Absence of mutations in the ATM gene in breast cancer patients with severe responses to radiotherapy

artículo científico publicado en 1997

An unrelated cytogenetic karyotype and intra-lineage shift at relapse of an aggressive paediatric B-precursor ALL

artículo científico publicado en 2002

Apoptotic resistance to ionizing radiation in pediatric B-precursor acute lymphoblastic leukemia frequently involves increased NF-kappaB survival pathway signaling.

artículo científico publicado en 2004

Assessment of p53 and ATM functionality in chronic lymphocytic leukemia by multiplex ligation-dependent probe amplification

artículo científico publicado en 2015

Ataxia telangiectasia mutated-deficient B-cell chronic lymphocytic leukemia occurs in pregerminal center cells and results in defective damage response and unrepaired chromosome damage

artículo científico publicado en 2002

BET inhibition as a single or combined therapeutic approach in primary paediatric B-precursor acute lymphoblastic leukaemia.

artículo científico publicado en 2013

CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions

artículo científico publicado en 2018

Clinical impact of clonal and subclonal TP53, SF3B1, BIRC3, NOTCH1, and ATM mutations in chronic lymphocytic leukemia.

artículo científico publicado en 2016

Clonal diversity of Ig and T-cell receptor gene rearrangements in childhood B-precursor acute lymphoblastic leukaemia.

artículo científico publicado en 2000

Clonal diversity, measured by heterogeneity of Ig and TCR gene rearrangements, in some acute leukaemias of childhood is associated with a more aggressive disease

scientific article published on 01 January 1995

Construction of a transcription map around the gene for ataxia telangiectasia: identification of at least four novel genes

artículo científico publicado en 1997

Down-regulation of ATM protein in HRS cells of nodular sclerosis Hodgkin's lymphoma in children occurs in the absence of ATM gene inactivation.

artículo científico publicado en 2007

Dynamic changes in clonal cytogenetic architecture during progression of chronic lymphocytic leukemia in patients and patient-derived murine xenografts

artículo científico publicado en 2017

Extreme telomere erosion in ATM-mutated and 11q-deleted CLL patients is independent of disease stage

scientific article published on 11 October 2011

Functional modules integrating essential cellular functions are predictive of the response of leukaemia cells to DNA damage.

artículo científico publicado en 2008

Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia

article

Insights into the multistep transformation process of lymphomas: IgH-associated translocations and tumor suppressor gene mutations in clonally related composite Hodgkin's and non-Hodgkin's lymphomas

article

Integrative analysis of spontaneous CLL regression highlights genetic and microenvironmental interdependency in CLL

scientific article published on 01 February 2020

Irradiation hybrids for human chromosome 11: characterization and use for generating region-specific markers in 11q14-q23.

artículo científico publicado en 1993

KIBRAgene methylation is associated with unfavorable biological prognostic parameters in chronic lymphocytic leukemia

artículo científico publicado en 2012

Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers.

artículo científico publicado en 2008

Microarray analysis reveals that TP53- and ATM-mutant B-CLLs share a defect in activating proapoptotic responses after DNA damage but are distinguished by major differences in activating prosurvival responses.

artículo científico publicado en 2003

Molecular analysis of single colonies reveals a diverse origin of initial clonal proliferation in B-precursor acute lymphoblastic leukemia that can precede the t(12;21) translocation

artículo científico publicado en 2001

Molecular mechanisms involved in chemoresistance in paediatric acute lymphoblastic leukaemia.

artículo científico publicado en 2008

Mutation status of the residual ATM allele is an important determinant of the cellular response to chemotherapy and survival in patients with chronic lymphocytic leukemia containing an 11q deletion.

artículo científico publicado en 2007

Mutations associated with variant phenotypes in ataxia-telangiectasia

artículo científico publicado en 1996

Mutations in the ATM gene lead to impaired overall and treatment-free survival that is independent of IGVH mutation status in patients with B-CLL.

artículo científico publicado en 2005

Mutations revealed by sequencing the 5' half of the gene for ataxia telangiectasia.

artículo científico publicado en 1996

NK cell function is markedly impaired in patients with chronic lymphocytic leukaemia but is preserved in patients with small lymphocytic lymphoma.

scientific article published on 17 September 2016

PALB2 variant status in hematological malignancies – a potential therapeutic target?

scientific article published on 07 January 2019

PFI-1, a highly selective protein interaction inhibitor, targeting BET Bromodomains

artículo científico publicado en 2013

Pathogenic ATM mutations occur rarely in a subset of multiple myeloma patients.

artículo científico publicado en 2008

Production and characterization of human proliferative T-cell clones specific for human papillomavirus type 1 E4 protein.

artículo científico publicado en 1993

RIDDLE immunodeficiency syndrome is linked to defects in 53BP1-mediated DNA damage signaling

artículo científico publicado en 2007

Rapid production of diversity during the progression of a mixed lineage leukaemia

artículo científico publicado en 1992

Recurrent ATM mutations in T-PLL on diverse haplotypes: no support for their germline origin

artículo científico publicado en 2001

Residual ataxia telangiectasia mutated protein function in cells from ataxia telangiectasia patients, with 5762ins137 and 7271T-->G mutations, showing a less severe phenotype.

artículo científico publicado en 2001

Signatures of TOP1 transcription-associated mutagenesis in cancer and germline

artículo científico publicado en 2022

Synergistic Action of Dual IGF1/R and MEK Inhibition Sensitizes Childhood Acute Lymphoblastic Leukaemia (ALL) Cells to Cytotoxic Agents and Involves Down-Regulation of STAT6 and PDAP1.

artículo científico publicado en 2018

Synthetic lethality in chronic lymphocytic leukaemia with DNA damage response defects by targeting the ATR pathway

artículo científico publicado en 2015

T-cell number and subtype influence the disease course of primary chronic lymphocytic leukaemia xenografts in alymphoid mice.

artículo científico publicado en 2015

TLR-9 and IL-15 Synergy Promotes the In Vitro Clonal Expansion of Chronic Lymphocytic Leukemia B Cells

artículo científico publicado en 2015

Targeting the Ataxia Telangiectasia Mutated-null phenotype in chronic lymphocytic leukemia with pro-oxidants

artículo científico publicado en 2015

Telomere length predicts progression and overall survival in chronic lymphocytic leukemia: data from the UK LRF CLL4 trial.

artículo científico publicado en 2015

The ATM tumour suppressor gene is down-regulated in EBV-associated nasopharyngeal carcinoma.

artículo científico publicado en 2009

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

scientific journal article

The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo.

artículo científico publicado en 2010

The dual-acting chemotherapeutic agent Alchemix induces cell death independently of ATM and p53.

artículo científico publicado en 2014

The impact of SF3B1 mutations in CLL on the DNA-damage response

artículo científico publicado en 2014

The role of ATM mutations and 11q deletions in disease progression in chronic lymphocytic leukemia.

artículo científico publicado en 2013

USP7 inhibition alters homologous recombination repair and targets CLL cells independently of ATM/p53 functional status

artículo científico publicado en 2017

USP7 is essential for maintaining Rad18 stability and DNA damage tolerance.

artículo científico publicado en 2015

ZAP-70 is highly expressed in most cases of childhood pre-B cell acute lymphoblastic leukemia.

artículo científico publicado en 2008

[Clinical manifestations of neuroblastoma in children and their effect on prognosis]

artículo científico publicado en 1989

[Glycogenosis IB in an infant]

artículo científico publicado en 1988

p53 dysfunction in B-cell chronic lymphocytic leukemia: inactivation of ATM as an alternative to TP53 mutation

scientific article published on 01 August 2001

Lista de obras de T Stankovic

A Hypomorphic PALB2 Allele Gives Rise to an Unusual Form of FA-N Associated with Lymphoid Tumour Development

A multi-centre phase I trial of the PARP inhibitor olaparib in patients with relapsed chronic lymphocytic leukaemia, T-prolymphocytic leukaemia or mantle cell lymphoma

A new minimal deleted region at 11q22.3 reveals the importance of interpretation of diminished FISH signals and the choice of probe for ATM deletion screening in chronic lymphocytic leukemia

A novel CDK inhibitor, CYC202 (R-roscovitine), overcomes the defect in p53-dependent apoptosis in B-CLL by down-regulation of genes involved in transcription regulation and survival.

A novel functional assay using etoposide plus nutlin-3a detects and distinguishes between ATM and TP53 mutations in CLL.

A physical map across chromosome 11q22-q23 containing the major locus for ataxia telangiectasia.

A regulatory role for NBS1 in strand-specific mutagenesis during somatic hypermutation

ATM mutation rather than BIRC3 deletion and/or mutation predicts reduced survival in 11q-deleted chronic lymphocytic leukemia: data from the UK LRF CLL4 trial.

ATM mutations in sporadic lymphoid tumours.

ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53- or ATM-defective chronic lymphocytic leukemia cells

Absence of mutations in the ATM gene in breast cancer patients with severe responses to radiotherapy

An unrelated cytogenetic karyotype and intra-lineage shift at relapse of an aggressive paediatric B-precursor ALL

Apoptotic resistance to ionizing radiation in pediatric B-precursor acute lymphoblastic leukemia frequently involves increased NF-kappaB survival pathway signaling.

Assessment of p53 and ATM functionality in chronic lymphocytic leukemia by multiplex ligation-dependent probe amplification

Ataxia telangiectasia mutated-deficient B-cell chronic lymphocytic leukemia occurs in pregerminal center cells and results in defective damage response and unrepaired chromosome damage

BET inhibition as a single or combined therapeutic approach in primary paediatric B-precursor acute lymphoblastic leukaemia.

CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions

Clinical impact of clonal and subclonal TP53, SF3B1, BIRC3, NOTCH1, and ATM mutations in chronic lymphocytic leukemia.

Clonal diversity of Ig and T-cell receptor gene rearrangements in childhood B-precursor acute lymphoblastic leukaemia.

Clonal diversity, measured by heterogeneity of Ig and TCR gene rearrangements, in some acute leukaemias of childhood is associated with a more aggressive disease

Construction of a transcription map around the gene for ataxia telangiectasia: identification of at least four novel genes

Down-regulation of ATM protein in HRS cells of nodular sclerosis Hodgkin's lymphoma in children occurs in the absence of ATM gene inactivation.

Dynamic changes in clonal cytogenetic architecture during progression of chronic lymphocytic leukemia in patients and patient-derived murine xenografts

Extreme telomere erosion in ATM-mutated and 11q-deleted CLL patients is independent of disease stage

Functional modules integrating essential cellular functions are predictive of the response of leukaemia cells to DNA damage.

Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia

Insights into the multistep transformation process of lymphomas: IgH-associated translocations and tumor suppressor gene mutations in clonally related composite Hodgkin's and non-Hodgkin's lymphomas

Integrative analysis of spontaneous CLL regression highlights genetic and microenvironmental interdependency in CLL

Irradiation hybrids for human chromosome 11: characterization and use for generating region-specific markers in 11q14-q23.

KIBRAgene methylation is associated with unfavorable biological prognostic parameters in chronic lymphocytic leukemia

Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers.

Microarray analysis reveals that TP53- and ATM-mutant B-CLLs share a defect in activating proapoptotic responses after DNA damage but are distinguished by major differences in activating prosurvival responses.

Molecular analysis of single colonies reveals a diverse origin of initial clonal proliferation in B-precursor acute lymphoblastic leukemia that can precede the t(12;21) translocation

Molecular mechanisms involved in chemoresistance in paediatric acute lymphoblastic leukaemia.

Mutation status of the residual ATM allele is an important determinant of the cellular response to chemotherapy and survival in patients with chronic lymphocytic leukemia containing an 11q deletion.

Mutations associated with variant phenotypes in ataxia-telangiectasia

Mutations in the ATM gene lead to impaired overall and treatment-free survival that is independent of IGVH mutation status in patients with B-CLL.

Mutations revealed by sequencing the 5' half of the gene for ataxia telangiectasia.

NK cell function is markedly impaired in patients with chronic lymphocytic leukaemia but is preserved in patients with small lymphocytic lymphoma.

PALB2 variant status in hematological malignancies – a potential therapeutic target?

PFI-1, a highly selective protein interaction inhibitor, targeting BET Bromodomains

Pathogenic ATM mutations occur rarely in a subset of multiple myeloma patients.

Production and characterization of human proliferative T-cell clones specific for human papillomavirus type 1 E4 protein.

RIDDLE immunodeficiency syndrome is linked to defects in 53BP1-mediated DNA damage signaling

Rapid production of diversity during the progression of a mixed lineage leukaemia

Recurrent ATM mutations in T-PLL on diverse haplotypes: no support for their germline origin

Residual ataxia telangiectasia mutated protein function in cells from ataxia telangiectasia patients, with 5762ins137 and 7271T-->G mutations, showing a less severe phenotype.

Signatures of TOP1 transcription-associated mutagenesis in cancer and germline

Synergistic Action of Dual IGF1/R and MEK Inhibition Sensitizes Childhood Acute Lymphoblastic Leukaemia (ALL) Cells to Cytotoxic Agents and Involves Down-Regulation of STAT6 and PDAP1.

Synthetic lethality in chronic lymphocytic leukaemia with DNA damage response defects by targeting the ATR pathway

T-cell number and subtype influence the disease course of primary chronic lymphocytic leukaemia xenografts in alymphoid mice.

TLR-9 and IL-15 Synergy Promotes the In Vitro Clonal Expansion of Chronic Lymphocytic Leukemia B Cells

Targeting the Ataxia Telangiectasia Mutated-null phenotype in chronic lymphocytic leukemia with pro-oxidants

Telomere length predicts progression and overall survival in chronic lymphocytic leukemia: data from the UK LRF CLL4 trial.

The ATM tumour suppressor gene is down-regulated in EBV-associated nasopharyngeal carcinoma.

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo.

The dual-acting chemotherapeutic agent Alchemix induces cell death independently of ATM and p53.

The impact of SF3B1 mutations in CLL on the DNA-damage response

The role of ATM mutations and 11q deletions in disease progression in chronic lymphocytic leukemia.

USP7 inhibition alters homologous recombination repair and targets CLL cells independently of ATM/p53 functional status

USP7 is essential for maintaining Rad18 stability and DNA damage tolerance.

ZAP-70 is highly expressed in most cases of childhood pre-B cell acute lymphoblastic leukemia.

[Clinical manifestations of neuroblastoma in children and their effect on prognosis]

[Glycogenosis IB in an infant]

p53 dysfunction in B-cell chronic lymphocytic leukemia: inactivation of ATM as an alternative to TP53 mutation