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Lista de obras de Roderick L Beijersbergen

A Functional Genetic Screen Identifies the Phosphoinositide 3-kinase Pathway as a Determinant of Resistance to Fibroblast Growth Factor Receptor Inhibitors in FGFR Mutant Urothelial Cell Carcinoma

artículo científico publicado en 2017

A Vulnerability of a Subset of Colon Cancers with Potential Clinical Utility.

artículo científico publicado en 2016

A loss-of-adhesion CRISPR-Cas9 screening platform to identify cell adhesion-regulatory proteins and signaling pathways

artículo científico publicado en 2022

A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers

artículo científico publicado en 2018

Bioassay development

article

CRISPR knockout screening outperforms shRNA and CRISPRi in identifying essential genes.

artículo científico publicado en 2016

EGFR overexpression induces activation of telomerase via PI3K/AKT‐mediated phosphorylation and transcriptional regulation through Hif1‐alpha in a cellular model of oral–esophageal carcinogenesis ⬇️

artículo científico publicado el 12 de diciembre de 2010

Exploration of Synthetic Lethal Interactions as Cancer Drug Targets ⬇️

artículo científico publicado el 1 de noviembre de 2010

Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer

artículo científico publicado en 2021

High-Throughput Functional Genetic and Compound Screens Identify Targets for Senescence Induction in Cancer

artículo científico publicado en 2017

Integrated in vivo genetic and pharmacologic screening identifies co-inhibition of EGRF and ROCK as a potential treatment regimen for triple-negative breast cancer

scientific article published on 22 June 2016

Intracellular signalling by binding sites for the antipsoriatic agent monomethylfumarate on human granulocytes ⬇️

artículo científico publicado el 1 de julio de 1997

Involvement of MINK, a Ste20 family kinase, in Ras oncogene-induced growth arrest in human ovarian surface epithelial cells

artículo científico publicado en 2005

Loss of ARID1A Activates ANXA1, which Serves as a Predictive Biomarker for Trastuzumab Resistance.

artículo científico publicado en 2016

Loss of p53 induces cell proliferation via Ras-independent activation of the Raf/Mek/Erk signaling pathway

artículo científico publicado en 2014

Miz1 and HectH9 regulate the stability of the checkpoint protein, TopBP1

artículo científico publicado en 2008

Neutrophils Kill Antibody-Opsonized Cancer Cells by Trogoptosis

artículo científico publicado en 2018

PIM kinases are a potential prognostic biomarker and therapeutic target in neuroblastoma

artículo científico publicado en 2018

Phosphatidylinositol 3-kinase hyperactivation results in lapatinib resistance that is reversed by the mTOR/phosphatidylinositol 3-kinase inhibitor NVP-BEZ235.

artículo científico publicado en 2008

Phospho-ERK is a biomarker of response to a synthetic lethal drug combination of sorafenib and MEK inhibition in liver cancer

scientific article published on 18 July 2018

Pooled shRNA Screening in Mammalian Cells as a Functional Genomic Discovery Platform

artículo científico publicado en 2016

SMARCE1 suppresses EGFR expression and controls responses to MET and ALK inhibitors in lung cancer

artículo científico publicado en 2015

Screening for modulators of cisplatin sensitivity: Unbiased screens reveal common themes ⬇️

artículo científico publicado el 1 de febrero de 2011

Sensitizing Triple-Negative Breast Cancer to PI3K Inhibition by Cotargeting IGF1R.

artículo científico publicado en 2016

Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma

artículo científico publicado en 2009

The lethal response to Cdk1 inhibition depends on sister chromatid alignment errors generated by KIF4 and isoform 1 of PRC1.

artículo científico publicado en 2015

The ubiquitin-specific protease USP28 is required for MYC stability

artículo científico publicado en 2007

ZNF423 is critically required for retinoic acid-induced differentiation and is a marker of neuroblastoma outcome

artículo científico publicado en 2009

hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization ⬇️

artículo científico publicado el 22 de agosto de 1997

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