Lista de obras - Mary Roberts - Dominio Público Uruguay

A Role for Weak Electrostatic Interactions in Peripheral Membrane Protein Binding

artículo científico publicado en 2016

A molecular-imprint nanosensor for ultrasensitive detection of proteins

artículo científico publicado en 2010

An iron-dependent bacterial phospholipase D reminiscent of purple acid phosphatases

artículo científico publicado en 2003

Antigen receptor-mediated changes in glucose metabolism in B lymphocytes: role of phosphatidylinositol 3-kinase signaling in the glycolytic control of growth

artículo científico publicado en 2006

Asymmetric Syntheses of L,L- and L,D-di-myo-inositol-1,1'-phosphate and their behavior as stabilizers of enzyme activity at extreme temperatures

artículo científico publicado en 2009

Avoidance of autophagy mediated by PlcA or ActA is required for Listeria monocytogenes growth in macrophages

artículo científico publicado en 2015

Ca2+-independent binding of anionic phospholipids by phospholipase C δ1 EF-hand domain

artículo científico publicado en 2013

Cation-π interactions as lipid-specific anchors for phosphatidylinositol-specific phospholipase C

artículo científico publicado en 2013

Chemistry and biology of deoxy-myo-inositol phosphates: stereospecificity of substrate interactions within an archaeal and a bacterial IMPase

artículo científico publicado en 2004

Cloning, overexpression, and characterization of a bacterial Ca2+-dependent phospholipase D

artículo científico publicado en 2002

Compatible solute effects on thermostability of glutamine synthetase and aspartate transcarbamoylase from Methanococcus jannaschii.

artículo científico publicado en 2005

Competition between Anion Binding and Dimerization Modulates Staphylococcus aureus Phosphatidylinositol-specific Phospholipase C Enzymatic Activity

artículo científico publicado en 2012

Correlation of vesicle binding and phospholipid dynamics with phospholipase C activity: insights into phosphatidylcholine activation and surface dilution inhibition

artículo científico publicado en 2009

Cross-linking phosphatidylinositol-specific phospholipase C traps two activating phosphatidylcholine molecules on the enzyme

artículo científico publicado en 2004

Crystal Structure of a Trapped Catalytic Intermediate Suggests that Forced Atomic Proximity Drives the Catalysis of mIPS ⬇️

artículo científico publicado el 7 de diciembre de 2011

Crystal structure of a dual activity IMPase/FBPase (AF2372) from Archaeoglobus fulgidus. The story of a mobile loop

artículo científico publicado en 2002

Crystal structure of the tetrameric inositol 1-phosphate phosphatase (TM1415) from the hyperthermophile, Thermotoga maritima

artículo científico publicado en 2007

Cutting edge: IL-4-mediated protection of primary B lymphocytes from apoptosis via Stat6-dependent regulation of glycolytic metabolism

artículo científico publicado en 2007

Cytotoxic amphiphiles and phosphoinositides bind to two discrete sites on the Akt1 PH domain

scientific article published on 10 January 2014

Defining a Viral Membrane-Remodeling Complex on an Atomic Level

artículo científico publicado en 2017

Defining specific lipid binding sites for a peripheral membrane protein in situ using subtesla field-cycling NMR.

artículo científico publicado en 2010

Dimer structure of an interfacially impaired phosphatidylinositol-specific phospholipase C

artículo científico publicado en 2007

Dissection of the steps of phospholipase C beta 2 activity that are enhanced by G beta gamma subunits

artículo científico publicado en 2005

Does changing the predicted dynamics of a phospholipase C alter activity and membrane binding?

artículo científico publicado en 2013

Dynamic Characteristics of Guanosine-5'-monophosphate Reductase Complexes Revealed by High-Resolution 31P Field-Cycling NMR Relaxometry.

artículo científico publicado en 2018

Enzyme-substrate-cofactor dynamical networks revealed by high resolution field cycling relaxometry

artículo científico publicado en 2020

Enzymology with a spin-labeled phospholipase C: soluble substrate binding by 31P NMR from 0.005 to 11.7 T

artículo científico publicado en 2009

Expression and characterization of a heterodimer of Streptomyces chromofuscus phospholipase D.

artículo científico publicado en 2004

Fluorescence correlation spectroscopy of phosphatidylinositol-specific phospholipase C monitors the interplay of substrate and activator lipid binding

artículo científico publicado en 2009

Fluorinated Aromatic Amino Acids Distinguish Cation-π Interactions from Membrane Insertion

artículo científico publicado en 2015

Genomic identification and in vitro reconstitution of a complete biosynthetic pathway for the osmolyte di-myo-inositol-phosphate.

artículo científico publicado en 2007

High-resolution 31p field cycling NMR as a probe of phospholipid dynamics

artículo científico publicado en 2004

High-resolution field-cycling NMR studies of a DNA octamer as a probe of phosphodiester dynamics and comparison with computer simulation

artículo científico publicado en 2004

Identification of hydrophobic interactions between proteins and lipids: free fatty acids activate phospholipase C delta1 via allosterism

artículo científico publicado en 2004

Inhibition of phosphatidylinositol 3-kinase-mediated glucose metabolism coincides with resveratrol-induced cell cycle arrest in human diffuse large B-cell lymphomas

artículo científico publicado en 2006

Inositol in bacteria and archaea

artículo científico publicado en 2006

Insights into the structural specificity of the cytotoxicity of 3-deoxyphosphatidylinositols

artículo científico publicado en 2008

Interfacial Aromatics Mediating Cation-π Interactions with Choline-Containing Lipids Can Contribute as Much to Peripheral Protein Affinity for Membranes as Aromatics Inserted below the Phosphates

scientific article published on 03 July 2019

Interfacial Choline-Aromatic Cation-Pi Interactions Can Contribute as Much to Peripheral Protein Affinity for Membranes as Aromatics Inserted Below the Phosphates

scholarly article published 5 June 2019

Investigating the interfacial binding of bacterial phosphatidylinositol-specific phospholipase C.

artículo científico publicado en 2003

Itaconic acid is a mammalian metabolite induced during macrophage activation

artículo científico publicado en 2011

Listeria monocytogenes phosphatidylinositol-specific phospholipase C: Kinetic activation and homing in on different interfaces

artículo científico publicado en 2009

Mobile loop mutations in an archaeal inositol monophosphatase: modulating three-metal ion assisted catalysis and lithium inhibition

artículo científico publicado en 2010

Modulation of Bacillus thuringiensis Phosphatidylinositol-specific Phospholipase C Activity by Mutations in the Putative Dimerization Interface

artículo científico publicado en 2009

Morphologic Patterns Formed by the Anomalous Fibers Occurring Along the Anterior Capsule of the Crystalline Lens in People With the Long Anterior Zonule Trait.

artículo científico publicado en 2017

Mutagenesis of Putative Catalytic and Regulatory Residues of Streptomyces chromofuscus Phospholipase D Differentially Modifies Phosphatase and Phosphodiesterase Activities ⬇️

artículo científico publicado el 13 de octubre de 2003

Mutation of two active-site residues converts a phosphatidylinositol-specific phospholipase C to a glucose phosphatase

artículo científico publicado en 2004

Non-HKD phospholipase D enzymes: new players in phosphatidic acid signaling?

artículo científico publicado en 2005

Optimizing the Interfacial Binding and Activity of a Bacterial Phosphatidylinositol-specific Phospholipase C ⬇️

artículo científico publicado el 24 de abril de 2003

Organic compatible solutes of halotolerant and halophilic microorganisms

artículo científico publicado en 2005

Osmoadaptation and osmoregulation in archaea: update 2004.

artículo científico publicado en 2004

Phosphatidylcholine "wobble" in vesicles assessed by high-resolution 13C field cycling NMR spectroscopy

artículo científico publicado en 2009

Phosphohydrolase and transphosphatidylation reactions of two Streptomyces phospholipase D enzymes: covalent versus noncovalent catalysis

artículo científico publicado en 2003

Phospholipid bilayer surface configuration probed quantitatively by (31)P field-cycling NMR.

artículo científico publicado en 2004

Phospholipid reorientation at the lipid/water interface measured by high resolution 31P field cycling NMR spectroscopy

artículo científico publicado en 2009

Phospholipid-binding sites of phosphatase and tensin homolog (PTEN): exploring the mechanism of phosphatidylinositol 4,5-bisphosphate activation

artículo científico publicado en 2014

Probing the mechanism of the Archaeoglobus fulgidus inositol-1-phosphate synthase

artículo científico publicado en 2005

Quantifying transient interactions between Bacillus phosphatidylinositol-specific phospholipase-C and phosphatidylcholine-rich vesicles.

artículo científico publicado en 2014

Reaching for mechanistic consensus across life kingdoms: structure and insights into catalysis of the myo-inositol-1-phosphate synthase (mIPS) from Archaeoglobus fulgidus

artículo científico publicado en 2005

Recombinant broad-range phospholipase C from Listeria monocytogenes exhibits optimal activity at acidic pH.

artículo científico publicado en 2016

Reflections on the journey: six short stories ⬇️

artículo científico publicado el 7 de noviembre de 2011

Remnants of the anterior tunica vasculosa lentis and long anterior lens zonules

artículo científico publicado en 2014

Role of helix B residues in interfacial activation of a bacterial phosphatidylinositol-specific phospholipase C.

artículo científico publicado en 2008

Role of tryptophan residues in interfacial binding of phosphatidylinositol-specific phospholipase C.

artículo científico publicado en 2002

Rotation of lipids in membranes: molecular dynamics simulation, 31P spin-lattice relaxation, and rigid-body dynamics

artículo científico publicado en 2008

Search and Subvert: Minimalist Bacterial Phosphatidylinositol-Specific Phospholipase C Enzymes

Solute accumulation in the deep-sea bacterium Photobacterium profundum

artículo científico publicado en 2002

Spectroscopic characterization of the EF-hand domain of phospholipase C delta1: identification of a lipid interacting domain.

artículo científico publicado en 2005

Structure of the S. aureus PI-Specific Phospholipase C Reveals Modulation of Active Site Access by a Titratable π-Cation Latched Loop ⬇️

artículo científico publicado el 16 de marzo de 2012

Structure of the inositol-1-phosphate cytidylyltransferase from Thermotoga maritima

artículo científico publicado en 2013

Substrate and Cofactor Dynamics on Guanosine Monophosphate Reductase Probed by High Resolution Field Cycling 31P NMR Relaxometry.

artículo científico publicado en 2016

The Cation- Box Is a Specific Phosphatidylcholine Membrane Targeting Motif

artículo científico publicado en 2013

The structure of the R184A mutant of the inositol monophosphatase encoded by suhB and implications for its functional interactions in Escherichia coli.

artículo científico publicado en 2007

The temperature dependence of the inositol monophosphatase Km correlates with accumulation of di-myo-inositol 1,1'-phosphate in Archaeoglobus fulgidus

artículo científico publicado en 2006

Understanding the stereospecific interactions of 3-deoxyphosphatidylinositol derivatives with the PTEN phosphatase domain

artículo científico publicado en 2010

Unexpected similarity in regulation between an archaeal inositol monophosphatase/fructose bisphosphatase and chloroplast fructose bisphosphatase

artículo científico publicado en 2003

Using O-(n-alkyl)-N-(N,N'-dimethylethyl)phosphoramidates to investigate the role of Ca2+ and interfacial binding in a bacterial phospholipase D

scientific article published on 01 July 2003

Water-miscible organic cosolvents enhance phosphatidylinositol-specific phospholipase C phosphotransferase as well as phosphodiesterase activity

artículo científico publicado en 2003

d-3-Deoxy-dioctanoylphosphatidylinositol induces cytotoxicity in human MCF-7 breast cancer cells via a mechanism that involves downregulation of the D-type cyclin-retinoblastoma pathway

artículo científico publicado en 2016

Lista de obras de Mary Roberts

A Role for Weak Electrostatic Interactions in Peripheral Membrane Protein Binding

A molecular-imprint nanosensor for ultrasensitive detection of proteins

An iron-dependent bacterial phospholipase D reminiscent of purple acid phosphatases

Antigen receptor-mediated changes in glucose metabolism in B lymphocytes: role of phosphatidylinositol 3-kinase signaling in the glycolytic control of growth

Asymmetric Syntheses of L,L- and L,D-di-myo-inositol-1,1'-phosphate and their behavior as stabilizers of enzyme activity at extreme temperatures

Avoidance of autophagy mediated by PlcA or ActA is required for Listeria monocytogenes growth in macrophages

Ca2+-independent binding of anionic phospholipids by phospholipase C δ1 EF-hand domain

Cation-π interactions as lipid-specific anchors for phosphatidylinositol-specific phospholipase C

Chemistry and biology of deoxy-myo-inositol phosphates: stereospecificity of substrate interactions within an archaeal and a bacterial IMPase

Cloning, overexpression, and characterization of a bacterial Ca2+-dependent phospholipase D

Compatible solute effects on thermostability of glutamine synthetase and aspartate transcarbamoylase from Methanococcus jannaschii.

Competition between Anion Binding and Dimerization Modulates Staphylococcus aureus Phosphatidylinositol-specific Phospholipase C Enzymatic Activity

Correlation of vesicle binding and phospholipid dynamics with phospholipase C activity: insights into phosphatidylcholine activation and surface dilution inhibition

Cross-linking phosphatidylinositol-specific phospholipase C traps two activating phosphatidylcholine molecules on the enzyme

Crystal Structure of a Trapped Catalytic Intermediate Suggests that Forced Atomic Proximity Drives the Catalysis of mIPS ⬇️

Crystal structure of a dual activity IMPase/FBPase (AF2372) from Archaeoglobus fulgidus. The story of a mobile loop

Crystal structure of the tetrameric inositol 1-phosphate phosphatase (TM1415) from the hyperthermophile, Thermotoga maritima

Cutting edge: IL-4-mediated protection of primary B lymphocytes from apoptosis via Stat6-dependent regulation of glycolytic metabolism

Cytotoxic amphiphiles and phosphoinositides bind to two discrete sites on the Akt1 PH domain

Defining a Viral Membrane-Remodeling Complex on an Atomic Level

Defining specific lipid binding sites for a peripheral membrane protein in situ using subtesla field-cycling NMR.

Dimer structure of an interfacially impaired phosphatidylinositol-specific phospholipase C

Dissection of the steps of phospholipase C beta 2 activity that are enhanced by G beta gamma subunits

Does changing the predicted dynamics of a phospholipase C alter activity and membrane binding?

Dynamic Characteristics of Guanosine-5'-monophosphate Reductase Complexes Revealed by High-Resolution 31P Field-Cycling NMR Relaxometry.

Enzyme-substrate-cofactor dynamical networks revealed by high resolution field cycling relaxometry

Enzymology with a spin-labeled phospholipase C: soluble substrate binding by 31P NMR from 0.005 to 11.7 T

Expression and characterization of a heterodimer of Streptomyces chromofuscus phospholipase D.

Fluorescence correlation spectroscopy of phosphatidylinositol-specific phospholipase C monitors the interplay of substrate and activator lipid binding

Fluorinated Aromatic Amino Acids Distinguish Cation-π Interactions from Membrane Insertion

Genomic identification and in vitro reconstitution of a complete biosynthetic pathway for the osmolyte di-myo-inositol-phosphate.

High-resolution 31p field cycling NMR as a probe of phospholipid dynamics

High-resolution field-cycling NMR studies of a DNA octamer as a probe of phosphodiester dynamics and comparison with computer simulation

Identification of hydrophobic interactions between proteins and lipids: free fatty acids activate phospholipase C delta1 via allosterism

Inhibition of phosphatidylinositol 3-kinase-mediated glucose metabolism coincides with resveratrol-induced cell cycle arrest in human diffuse large B-cell lymphomas

Inositol in bacteria and archaea

Insights into the structural specificity of the cytotoxicity of 3-deoxyphosphatidylinositols

Interfacial Aromatics Mediating Cation-π Interactions with Choline-Containing Lipids Can Contribute as Much to Peripheral Protein Affinity for Membranes as Aromatics Inserted below the Phosphates

Interfacial Choline-Aromatic Cation-Pi Interactions Can Contribute as Much to Peripheral Protein Affinity for Membranes as Aromatics Inserted Below the Phosphates

Investigating the interfacial binding of bacterial phosphatidylinositol-specific phospholipase C.

Itaconic acid is a mammalian metabolite induced during macrophage activation

Listeria monocytogenes phosphatidylinositol-specific phospholipase C: Kinetic activation and homing in on different interfaces

Mobile loop mutations in an archaeal inositol monophosphatase: modulating three-metal ion assisted catalysis and lithium inhibition

Modulation of Bacillus thuringiensis Phosphatidylinositol-specific Phospholipase C Activity by Mutations in the Putative Dimerization Interface

Morphologic Patterns Formed by the Anomalous Fibers Occurring Along the Anterior Capsule of the Crystalline Lens in People With the Long Anterior Zonule Trait.

Mutagenesis of Putative Catalytic and Regulatory Residues of Streptomyces chromofuscus Phospholipase D Differentially Modifies Phosphatase and Phosphodiesterase Activities ⬇️

Mutation of two active-site residues converts a phosphatidylinositol-specific phospholipase C to a glucose phosphatase

Non-HKD phospholipase D enzymes: new players in phosphatidic acid signaling?

Optimizing the Interfacial Binding and Activity of a Bacterial Phosphatidylinositol-specific Phospholipase C ⬇️

Organic compatible solutes of halotolerant and halophilic microorganisms

Osmoadaptation and osmoregulation in archaea: update 2004.

Phosphatidylcholine "wobble" in vesicles assessed by high-resolution 13C field cycling NMR spectroscopy

Phosphohydrolase and transphosphatidylation reactions of two Streptomyces phospholipase D enzymes: covalent versus noncovalent catalysis

Phospholipid bilayer surface configuration probed quantitatively by (31)P field-cycling NMR.

Phospholipid reorientation at the lipid/water interface measured by high resolution 31P field cycling NMR spectroscopy

Phospholipid-binding sites of phosphatase and tensin homolog (PTEN): exploring the mechanism of phosphatidylinositol 4,5-bisphosphate activation

Probing the mechanism of the Archaeoglobus fulgidus inositol-1-phosphate synthase

Quantifying transient interactions between Bacillus phosphatidylinositol-specific phospholipase-C and phosphatidylcholine-rich vesicles.

Reaching for mechanistic consensus across life kingdoms: structure and insights into catalysis of the myo-inositol-1-phosphate synthase (mIPS) from Archaeoglobus fulgidus

Recombinant broad-range phospholipase C from Listeria monocytogenes exhibits optimal activity at acidic pH.

Reflections on the journey: six short stories ⬇️

Remnants of the anterior tunica vasculosa lentis and long anterior lens zonules

Role of helix B residues in interfacial activation of a bacterial phosphatidylinositol-specific phospholipase C.

Role of tryptophan residues in interfacial binding of phosphatidylinositol-specific phospholipase C.

Rotation of lipids in membranes: molecular dynamics simulation, 31P spin-lattice relaxation, and rigid-body dynamics

Search and Subvert: Minimalist Bacterial Phosphatidylinositol-Specific Phospholipase C Enzymes

Solute accumulation in the deep-sea bacterium Photobacterium profundum

Spectroscopic characterization of the EF-hand domain of phospholipase C delta1: identification of a lipid interacting domain.

Structure of the S. aureus PI-Specific Phospholipase C Reveals Modulation of Active Site Access by a Titratable π-Cation Latched Loop ⬇️

Structure of the inositol-1-phosphate cytidylyltransferase from Thermotoga maritima

Substrate and Cofactor Dynamics on Guanosine Monophosphate Reductase Probed by High Resolution Field Cycling 31P NMR Relaxometry.

The Cation- Box Is a Specific Phosphatidylcholine Membrane Targeting Motif

The structure of the R184A mutant of the inositol monophosphatase encoded by suhB and implications for its functional interactions in Escherichia coli.

The temperature dependence of the inositol monophosphatase Km correlates with accumulation of di-myo-inositol 1,1'-phosphate in Archaeoglobus fulgidus

Understanding the stereospecific interactions of 3-deoxyphosphatidylinositol derivatives with the PTEN phosphatase domain

Unexpected similarity in regulation between an archaeal inositol monophosphatase/fructose bisphosphatase and chloroplast fructose bisphosphatase

Using O-(n-alkyl)-N-(N,N'-dimethylethyl)phosphoramidates to investigate the role of Ca2+ and interfacial binding in a bacterial phospholipase D

Water-miscible organic cosolvents enhance phosphatidylinositol-specific phospholipase C phosphotransferase as well as phosphodiesterase activity

d-3-Deoxy-dioctanoylphosphatidylinositol induces cytotoxicity in human MCF-7 breast cancer cells via a mechanism that involves downregulation of the D-type cyclin-retinoblastoma pathway