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Lista de obras de Thomas M Keck

A Novel Class of Dopamine D4 Receptor Ligands Bearing an Imidazoline Nucleus

artículo científico publicado en 2016

A novel mGluR5 antagonist, MFZ 10-7, inhibits cocaine-taking and cocaine-seeking behavior in rats

artículo científico publicado en 2013

Beyond small-molecule SAR: using the dopamine D3 receptor crystal structure to guide drug design

artículo científico publicado en 2014

Chiral Resolution and Serendipitous Fluorination Reaction for the Selective Dopamine D3 Receptor Antagonist BAK2-66

artículo científico publicado en 2014

Discovery, Optimization and Characterization of ML417: A Novel and Highly Selective D3 Dopamine Receptor Agonist

scientific article published on 28 April 2020

Dopamine D Receptor-Selective Compounds Reveal Structure-Activity Relationships that Engender Agonist Efficacy

artículo científico publicado en 2019

Dopamine D4 receptor deficiency in mice alters behavioral responses to anxiogenic stimuli and the psychostimulant methylphenidate.

artículo científico publicado en 2012

Fenobam sulfate inhibits cocaine-taking and cocaine-seeking behavior in rats: implications for addiction treatment in humans.

artículo científico publicado en 2013

High Affinity Dopamine D3 Receptor (D3R)-Selective Antagonists Attenuate Heroin Self-Administration in Wild-Type but not D3R Knockout Mice.

artículo científico publicado en 2015

Highly Selective Dopamine D3 Receptor (D3R) Antagonists and Partial Agonists Based on Eticlopride and the D3R Crystal Structure: New Leads for Opioid Dependence Treatment.

artículo científico publicado en 2016

Multitarget 1,4-Dioxane Compounds Combining Favorable D2-like and 5-HT1A Receptor Interactions with Potential for the Treatment of Parkinson's Disease or Schizophrenia

scientific article published on 09 January 2019

Novel Analogues of (R)-5-(Methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Sumanirole) Provide Clues to Dopamine D2/D3 Receptor Agonist Selectivity

artículo científico publicado en 2016

Synthesis and Pharmacological Characterization of Novel trans-Cyclopropylmethyl-Linked Bivalent Ligands That Exhibit Selectivity and Allosteric Pharmacology at the Dopamine D3 Receptor (D3R).

artículo científico publicado en 2017

The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT1A receptor over α1-adrenoceptor and D2-like receptor subtypes

artículo científico publicado en 2016

Toward Understanding the Structural Basis of Partial Agonism at the Dopamine D3 Receptor

artículo científico publicado en 2016

Tranylcypromine substituted cis-hydroxycyclobutylnaphthamides as potent and selective dopamine D₃ receptor antagonists.

artículo científico publicado en 2014

Using click chemistry toward novel 1,2,3-triazole-linked dopamine D3 receptor ligands

artículo científico publicado en 2015

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