Lista de obras - Christoph Arenz - Dominio Público Uruguay

A Fast and Easy Method for Specific Detection of Circular RNA by Rolling-Circle Amplification

scientific article published on 27 November 2019

A Rapid Assay for miRNA Maturation by Using Unmodified pre‐miRNA ⬇️

artículo científico publicado el 18 de agosto de 2011

A Scaffold-Tree-Merging Strategy for Prospective Bioactivity Annotation of γ-Pyrones

artículo científico publicado en 2010

A chemo-enzymatic approach to specifically click-modified RNA.

artículo científico publicado en 2013

A photocaged inhibitor of acid sphingomyelinase

artículo científico publicado en 2020

A series of ceramide analogs modified at the 1-position with potent activity against the intracellular growth of Chlamydia trachomatis

artículo científico publicado en 2015

Amplification of a FRET Probe by Lipid-Water Partition for the Detection of Acid Sphingomyelinase in Live Cells.

artículo científico publicado en 2017

Assaying Dicer-mediated miRNA maturation by means of fluorescent substrates

artículo científico publicado en 2014

CFTR and sphingolipids mediate hypoxic pulmonary vasoconstriction

artículo científico publicado en 2015

DNA made of purines only.

artículo científico publicado en 2007

Detection of microRNA maturation using unmodified pre-microRNA and branched rolling circle amplification.

artículo científico publicado en 2014

Development of an assay for the intermembrane transfer of cholesterol by Niemann-Pick C2 protein

article

Development of carbohydrate-derived inhibitors of acid sphingomyelinase.

artículo científico publicado en 2009

Differences and Similarities in TRAIL- and Tumor Necrosis Factor-Mediated Necroptotic Signaling in Cancer Cells

artículo científico publicado en 2016

Differential-Mobility Spectrometry of 1-Deoxysphingosine Isomers: New Insights into the Gas Phase Structures of Ionized Lipids.

artículo científico publicado en 2018

Elemental labelling and mass spectrometry for the specific detection of sulfenic acid groups in model peptides: a proof of concept

artículo científico publicado en 2017

FRET probes for measuring sphingolipid metabolizing enzyme activity

scholarly article by Zainelabdeen H Mohamed published in September 2018

Facile synthesis of the CERT inhibitor HPA-12 and some novel derivatives

artículo científico publicado en 2014

Heat shock protein-based therapy as a potential candidate for treating the sphingolipidoses.

artículo científico publicado en 2016

Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology.

artículo científico publicado en 2010

Identification of Small-Molecule Inhibitors of Neutral Ceramidase (nCDase) via Target-Based High-Throughput Screening

artículo científico publicado en 2020

Improved plaque assay identifies a novel anti-Chlamydia ceramide derivative with altered intracellular localization

artículo científico publicado en 2014

Inhibitors of Ceramidases

artículo científico

Labeled chemical biology tools for investigating sphingolipid metabolism, trafficking and interaction with lipids and proteins.

artículo científico

Long endogenous dsRNAs can induce complete gene silencing in mammalian cells and primary cultures.

artículo científico publicado en 2003

Lung endothelial Ca2+ and permeability response to platelet-activating factor is mediated by acid sphingomyelinase and transient receptor potential classical 6.

artículo científico publicado en 2012

Manumycin A and its analogues are irreversible inhibitors of neutral sphingomyelinase

scientific article published on 01 February 2001

MicroRNA maturation and human disease.

artículo científico

MicroRNA-145-targeted drug and its preventive effect on pulmonary arterial hypertension (patent WO2012153135 A1).

artículo científico publicado en 2015

Novel amide- and sulfonamide-based aromatic ethanolamines: Effects of various substituents on the inhibition of acid and neutral ceramidases ⬇️

artículo científico publicado el 31 de agosto de 2012

Novel fluorescent ceramide derivatives for probing ceramidase substrate specificity ⬇️

artículo científico publicado el 31 de agosto de 2012

Perspectives in targeting miRNA function.

artículo científico publicado en 2013

Phosphatidylinositol-3,5-Bisphosphate Is a Potent and Selective Inhibitor of Acid Sphingomyelinase ⬇️

artículo científico publicado el 1 de septiembre de 2003

Potent and selective inhibition of acid sphingomyelinase by bisphosphonates

artículo científico publicado en 2009

Potent inhibition of acid sphingomyelinase by phosphoinositide analogues.

artículo científico publicado en 2009

RNA Interference: Analyzing the Function of Glycoproteins and Glycosylating Proteins in Mammalian Cells

artículo científico publicado el 1 de enero de 2003

RNA interference: from an ancient mechanism to a state of the art therapeutic application?

artículo científico publicado en 2003

Recent advances and novel treatments for sphingolipidoses

artículo científico

Regioselective Diazo-Transfer Reaction at the C3-Position of the 2-Desoxystreptamine Ring of Neamine Antibiotics

artículo científico publicado en 2013

Rolling-circle amplification: unshared advantages in miRNA detection.

artículo científico publicado en 2009

SERS and Cryo-EM Directly Reveal Different Liposome Structures during Interaction with Gold Nanoparticles

scientific article published on 15 November 2018

Small molecule inhibitors of acid sphingomyelinase.

scientific article published on 18 May 2010

Small molecule inhibitors of ceramidases.

artículo científico publicado en 2014

Sphingolipid-Transporting Proteins as Cancer Therapeutic Targets

scientific article published on 20 July 2019

Structural insights into adiponectin receptors suggest ceramidase activity.

artículo científico publicado en 2017

Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy

artículo científico publicado en 2018

Subunit composition of the mammalian serine-palmitoyltransferase defines the spectrum of straight and methyl-branched long-chain bases

artículo científico publicado en 2020

Synthesis and biochemical investigation of scyphostatin analogues as inhibitors of neutral sphingomyelinase.

artículo científico publicado en 2001

Synthesis and characterization of some atypical sphingoid bases

artículo científico publicado en 2018

Synthesis of the First Selective Irreversible Inhibitor of Neutral Sphingomyelinase

scientific article published on 01 April 2000

The cellular ceramide transport protein CERT promotes Chlamydia psittaci infection and controls bacterial sphingolipid uptake.

artículo científico publicado en 2017

Transformation-associated changes in sphingolipid metabolism sensitize cells to lysosomal cell death induced by inhibitors of acid sphingomyelinase

artículo científico publicado en 2013

Tsc3 regulates SPT amino acid choice in Saccharomyces cerevisiae by promoting alanine in the sphingolipid pathway

artículo científico publicado en 2018

miRNAs as novel therapeutic targets and diagnostic biomarkers for Parkinson's disease: a patent evaluation of WO2014018650.

artículo científico publicado en 2014

Lista de obras de Christoph Arenz

A Fast and Easy Method for Specific Detection of Circular RNA by Rolling-Circle Amplification

A Rapid Assay for miRNA Maturation by Using Unmodified pre‐miRNA ⬇️

A Scaffold-Tree-Merging Strategy for Prospective Bioactivity Annotation of γ-Pyrones

A chemo-enzymatic approach to specifically click-modified RNA.

A photocaged inhibitor of acid sphingomyelinase

A series of ceramide analogs modified at the 1-position with potent activity against the intracellular growth of Chlamydia trachomatis

Amplification of a FRET Probe by Lipid-Water Partition for the Detection of Acid Sphingomyelinase in Live Cells.

Assaying Dicer-mediated miRNA maturation by means of fluorescent substrates

CFTR and sphingolipids mediate hypoxic pulmonary vasoconstriction

DNA made of purines only.

Detection of microRNA maturation using unmodified pre-microRNA and branched rolling circle amplification.

Development of an assay for the intermembrane transfer of cholesterol by Niemann-Pick C2 protein

Development of carbohydrate-derived inhibitors of acid sphingomyelinase.

Differences and Similarities in TRAIL- and Tumor Necrosis Factor-Mediated Necroptotic Signaling in Cancer Cells

Differential-Mobility Spectrometry of 1-Deoxysphingosine Isomers: New Insights into the Gas Phase Structures of Ionized Lipids.

Elemental labelling and mass spectrometry for the specific detection of sulfenic acid groups in model peptides: a proof of concept

FRET probes for measuring sphingolipid metabolizing enzyme activity

Facile synthesis of the CERT inhibitor HPA-12 and some novel derivatives

Heat shock protein-based therapy as a potential candidate for treating the sphingolipidoses.

Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology.

Identification of Small-Molecule Inhibitors of Neutral Ceramidase (nCDase) via Target-Based High-Throughput Screening

Improved plaque assay identifies a novel anti-Chlamydia ceramide derivative with altered intracellular localization

Inhibitors of Ceramidases

Labeled chemical biology tools for investigating sphingolipid metabolism, trafficking and interaction with lipids and proteins.

Long endogenous dsRNAs can induce complete gene silencing in mammalian cells and primary cultures.

Lung endothelial Ca2+ and permeability response to platelet-activating factor is mediated by acid sphingomyelinase and transient receptor potential classical 6.

Manumycin A and its analogues are irreversible inhibitors of neutral sphingomyelinase

MicroRNA maturation and human disease.

MicroRNA-145-targeted drug and its preventive effect on pulmonary arterial hypertension (patent WO2012153135 A1).

Novel amide- and sulfonamide-based aromatic ethanolamines: Effects of various substituents on the inhibition of acid and neutral ceramidases ⬇️

Novel fluorescent ceramide derivatives for probing ceramidase substrate specificity ⬇️

Perspectives in targeting miRNA function.

Phosphatidylinositol-3,5-Bisphosphate Is a Potent and Selective Inhibitor of Acid Sphingomyelinase ⬇️

Potent and selective inhibition of acid sphingomyelinase by bisphosphonates

Potent inhibition of acid sphingomyelinase by phosphoinositide analogues.

RNA Interference: Analyzing the Function of Glycoproteins and Glycosylating Proteins in Mammalian Cells

RNA interference: from an ancient mechanism to a state of the art therapeutic application?

Recent advances and novel treatments for sphingolipidoses

Regioselective Diazo-Transfer Reaction at the C3-Position of the 2-Desoxystreptamine Ring of Neamine Antibiotics

Rolling-circle amplification: unshared advantages in miRNA detection.

SERS and Cryo-EM Directly Reveal Different Liposome Structures during Interaction with Gold Nanoparticles

Small molecule inhibitors of acid sphingomyelinase.

Small molecule inhibitors of ceramidases.

Sphingolipid-Transporting Proteins as Cancer Therapeutic Targets

Structural insights into adiponectin receptors suggest ceramidase activity.

Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy

Subunit composition of the mammalian serine-palmitoyltransferase defines the spectrum of straight and methyl-branched long-chain bases

Synthesis and biochemical investigation of scyphostatin analogues as inhibitors of neutral sphingomyelinase.

Synthesis and characterization of some atypical sphingoid bases

Synthesis of the First Selective Irreversible Inhibitor of Neutral Sphingomyelinase

The cellular ceramide transport protein CERT promotes Chlamydia psittaci infection and controls bacterial sphingolipid uptake.

Transformation-associated changes in sphingolipid metabolism sensitize cells to lysosomal cell death induced by inhibitors of acid sphingomyelinase

Tsc3 regulates SPT amino acid choice in Saccharomyces cerevisiae by promoting alanine in the sphingolipid pathway

miRNAs as novel therapeutic targets and diagnostic biomarkers for Parkinson's disease: a patent evaluation of WO2014018650.