Lista de obras - Lachlan H Thompson - Dominio Público Uruguay

A PITX3-EGFP Reporter Line Reveals Connectivity of Dopamine and Non-dopamine Neuronal Subtypes in Grafts Generated from Human Embryonic Stem Cells

artículo científico publicado en 2017

Axonal Growth of Midbrain Dopamine Neurons is Modulated by the Cell Adhesion Molecule ALCAM Through Trans-Heterophilic Interactions with L1cam, Chl1, and Semaphorins

scientific article published on 12 July 2019

Birth dating of midbrain dopamine neurons identifies A9 enriched tissue for transplantation into parkinsonian mice.

artículo científico publicado en 2012

Cell intrinsic and extrinsic factors contribute to enhance neural circuit reconstruction following transplantation in Parkinsonian mice.

artículo científico publicado en 2012

Characterization of Meteorin--an evolutionary conserved neurotrophic factor.

artículo científico publicado en 2009

Chondroitinase improves midbrain pathway reconstruction by transplanted dopamine progenitors in Parkinsonian mice.

artículo científico publicado en 2015

Cometin is a novel neurotrophic factor that promotes neurite outgrowth and neuroblast migration in vitro and supports survival of spiral ganglion neurons in vivo

artículo científico publicado en 2011

Developing stem cell-based therapies for neural repair

artículo científico publicado en 2013

Differential dopamine receptor occupancy underlies L-DOPA-induced dyskinesia in a rat model of Parkinson's disease

artículo científico publicado en 2014

Dynamics of transgene expression in a neural stem cell line transduced with lentiviral vectors incorporating the cHS4 insulator.

artículo científico publicado en 2004

Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells

scholarly article

Efficiently Specified Ventral Midbrain Dopamine Neurons from Human Pluripotent Stem Cells Under Xeno-Free Conditions Restore Motor Deficits in Parkinsonian Rodents.

artículo científico publicado en 2016

Functional characterization of Friedreich ataxia iPS-derived neuronal progenitors and their integration in the adult brain

artículo científico publicado en 2014

Functional properties and synaptic integration of genetically labelled dopaminergic neurons in intrastriatal grafts.

artículo científico publicado en 2005

GIRK2 expression in dopamine neurons of the substantia nigra and ventral tegmental area.

artículo científico publicado en 2012

Generation of striatal projection neurons extends into the neonatal period in the rat brain.

artículo científico publicado en 2012

Gli1 is an inducing factor in generating floor plate progenitor cells from human embryonic stem cells

artículo científico publicado en 2010

Glycogen synthase kinase 3β and activin/nodal inhibition in human embryonic stem cells induces a pre-neuroepithelial state that is required for specification to a floor plate cell lineage.

artículo científico publicado en 2012

Hippocampal Lewy pathology and cholinergic dysfunction are associated with dementia in Parkinson's disease.

artículo científico publicado en 2014

Histological characterization and quantification of newborn cells in the adult rodent brain

artículo científico publicado en 2021

Homophilic binding of the neural cell adhesion molecule CHL1 regulates development of ventral midbrain dopaminergic pathways.

artículo científico publicado en 2017

Identification of dopaminergic neurons of nigral and ventral tegmental area subtypes in grafts of fetal ventral mesencephalon based on cell morphology, protein expression, and efferent projections.

artículo científico publicado en 2005

Identification of transplantable dopamine neuron precursors at different stages of midbrain neurogenesis.

artículo científico publicado en 2009

In vivo gene delivery to proliferating cells in the striatum generated in response to a 6-hydroxydopamine lesion of the nigro-striatal dopamine pathway

artículo científico publicado en 2008

Isolation and characterization of neural precursor cells from the Sox1-GFP reporter mouse.

artículo científico publicado en 2005

Isolation of LMX1a Ventral Midbrain Progenitors Improves the Safety and Predictability of Human Pluripotent Stem Cell-Derived Neural Transplants in Parkinsonian Disease

artículo científico publicado en 2019

Lentiviral delivery of meteorin protects striatal neurons against excitotoxicity and reverses motor deficits in the quinolinic acid rat model.

artículo científico publicado en 2010

Local injection of Endothelin-1 in the early neonatal rat brain models ischemic damage associated with motor impairment and diffuse loss in brain volume

artículo científico publicado en 2018

Long-Distance Axonal Growth and Protracted Functional Maturation of Neurons Derived from Human Induced Pluripotent Stem Cells After Intracerebral Transplantation.

artículo científico publicado en 2017

Long-Term Motor Deficit and Diffuse Cortical Atrophy Following Focal Cortical Ischemia in Athymic Rats

artículo científico publicado en 2019

Meningeal cells influence midbrain development and the engraftment of dopamine progenitors in Parkinsonian mice.

artículo científico publicado en 2015

Modelling the dopamine and noradrenergic cell loss that occurs in Parkinson's disease and the impact on hippocampal neurogenesis

artículo científico publicado en 2018

Modulating Wnt signaling to improve cell replacement therapy for Parkinson's disease.

artículo científico

Neurogenin2 identifies a transplantable dopamine neuron precursor in the developing ventral mesencephalon

artículo científico publicado en 2006

Neurons derived from human embryonic stem cells extend long-distance axonal projections through growth along host white matter tracts after intra-cerebral transplantation.

artículo científico publicado en 2012

Non-dopaminergic neurons in ventral mesencephalic transplants make widespread axonal connections in the host brain.

artículo científico publicado en 2008

Novel pluripotent stem cell lines for enriched grafting in Parkinson's disease

artículo científico publicado en 2020

Over-Expression of Meteorin Drives Gliogenesis Following Striatal Injury

scientific article published on 05 July 2016

Peptide-Based Scaffolds Support Human Cortical Progenitor Graft Integration to Reduce Atrophy and Promote Functional Repair in a Model of Stroke.

artículo científico publicado en 2017

Reconstruction of brain circuitry by neural transplants generated from pluripotent stem cells

artículo científico

Reconstruction of the nigrostriatal dopamine pathway in the adult mouse brain.

artículo científico publicado en 2009

Specification of murine ground state pluripotent stem cells to regional neuronal populations.

artículo científico publicado en 2017

Survival, differentiation, and connectivity of ventral mesencephalic dopamine neurons following transplantation.

artículo científico publicado en 2012

The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson's disease

artículo científico publicado en 2010

Transcriptional Profiling of Xenogeneic Transplants: Examining Human Pluripotent Stem Cell-Derived Grafts in the Rodent Brain

scientific article published on 31 October 2019

Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors

artículo científico publicado en 2015

Transgenic reporter mice as tools for studies of transplantability and connectivity of dopamine neuron precursors in fetal tissue grafts

artículo científico publicado en 2009

Transplantation of Fetal Midbrain Dopamine Progenitors into a Rodent Model of Parkinson’s Disease ⬇️

artículo científico publicado el 1 de enero de 2013

Trophic factors differentiate dopamine neurons vulnerable to Parkinson's disease.

artículo científico publicado en 2012

Understanding the Influence of Target Acquisition on Survival, Integration, and Phenotypic Maturation of Dopamine Neurons within Stem Cell-Derived Neural Grafts in a Parkinson's Disease Model

artículo científico publicado en 2022

Lista de obras de Lachlan H Thompson

A PITX3-EGFP Reporter Line Reveals Connectivity of Dopamine and Non-dopamine Neuronal Subtypes in Grafts Generated from Human Embryonic Stem Cells

Axonal Growth of Midbrain Dopamine Neurons is Modulated by the Cell Adhesion Molecule ALCAM Through Trans-Heterophilic Interactions with L1cam, Chl1, and Semaphorins

Birth dating of midbrain dopamine neurons identifies A9 enriched tissue for transplantation into parkinsonian mice.

Cell intrinsic and extrinsic factors contribute to enhance neural circuit reconstruction following transplantation in Parkinsonian mice.

Characterization of Meteorin--an evolutionary conserved neurotrophic factor.

Chondroitinase improves midbrain pathway reconstruction by transplanted dopamine progenitors in Parkinsonian mice.

Cometin is a novel neurotrophic factor that promotes neurite outgrowth and neuroblast migration in vitro and supports survival of spiral ganglion neurons in vivo

Developing stem cell-based therapies for neural repair

Differential dopamine receptor occupancy underlies L-DOPA-induced dyskinesia in a rat model of Parkinson's disease

Dynamics of transgene expression in a neural stem cell line transduced with lentiviral vectors incorporating the cHS4 insulator.

Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells

Efficiently Specified Ventral Midbrain Dopamine Neurons from Human Pluripotent Stem Cells Under Xeno-Free Conditions Restore Motor Deficits in Parkinsonian Rodents.

Functional characterization of Friedreich ataxia iPS-derived neuronal progenitors and their integration in the adult brain

Functional properties and synaptic integration of genetically labelled dopaminergic neurons in intrastriatal grafts.

GIRK2 expression in dopamine neurons of the substantia nigra and ventral tegmental area.

Generation of striatal projection neurons extends into the neonatal period in the rat brain.

Gli1 is an inducing factor in generating floor plate progenitor cells from human embryonic stem cells

Glycogen synthase kinase 3β and activin/nodal inhibition in human embryonic stem cells induces a pre-neuroepithelial state that is required for specification to a floor plate cell lineage.

Hippocampal Lewy pathology and cholinergic dysfunction are associated with dementia in Parkinson's disease.

Histological characterization and quantification of newborn cells in the adult rodent brain

Homophilic binding of the neural cell adhesion molecule CHL1 regulates development of ventral midbrain dopaminergic pathways.

Identification of dopaminergic neurons of nigral and ventral tegmental area subtypes in grafts of fetal ventral mesencephalon based on cell morphology, protein expression, and efferent projections.

Identification of transplantable dopamine neuron precursors at different stages of midbrain neurogenesis.

In vivo gene delivery to proliferating cells in the striatum generated in response to a 6-hydroxydopamine lesion of the nigro-striatal dopamine pathway

Isolation and characterization of neural precursor cells from the Sox1-GFP reporter mouse.

Isolation of LMX1a Ventral Midbrain Progenitors Improves the Safety and Predictability of Human Pluripotent Stem Cell-Derived Neural Transplants in Parkinsonian Disease

Lentiviral delivery of meteorin protects striatal neurons against excitotoxicity and reverses motor deficits in the quinolinic acid rat model.

Local injection of Endothelin-1 in the early neonatal rat brain models ischemic damage associated with motor impairment and diffuse loss in brain volume

Long-Distance Axonal Growth and Protracted Functional Maturation of Neurons Derived from Human Induced Pluripotent Stem Cells After Intracerebral Transplantation.

Long-Term Motor Deficit and Diffuse Cortical Atrophy Following Focal Cortical Ischemia in Athymic Rats

Meningeal cells influence midbrain development and the engraftment of dopamine progenitors in Parkinsonian mice.

Modelling the dopamine and noradrenergic cell loss that occurs in Parkinson's disease and the impact on hippocampal neurogenesis

Modulating Wnt signaling to improve cell replacement therapy for Parkinson's disease.

Neurogenin2 identifies a transplantable dopamine neuron precursor in the developing ventral mesencephalon

Neurons derived from human embryonic stem cells extend long-distance axonal projections through growth along host white matter tracts after intra-cerebral transplantation.

Non-dopaminergic neurons in ventral mesencephalic transplants make widespread axonal connections in the host brain.

Novel pluripotent stem cell lines for enriched grafting in Parkinson's disease

Over-Expression of Meteorin Drives Gliogenesis Following Striatal Injury

Peptide-Based Scaffolds Support Human Cortical Progenitor Graft Integration to Reduce Atrophy and Promote Functional Repair in a Model of Stroke.

Reconstruction of brain circuitry by neural transplants generated from pluripotent stem cells

Reconstruction of the nigrostriatal dopamine pathway in the adult mouse brain.

Specification of murine ground state pluripotent stem cells to regional neuronal populations.

Survival, differentiation, and connectivity of ventral mesencephalic dopamine neurons following transplantation.

The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson's disease

Transcriptional Profiling of Xenogeneic Transplants: Examining Human Pluripotent Stem Cell-Derived Grafts in the Rodent Brain

Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors

Transgenic reporter mice as tools for studies of transplantability and connectivity of dopamine neuron precursors in fetal tissue grafts

Transplantation of Fetal Midbrain Dopamine Progenitors into a Rodent Model of Parkinson’s Disease ⬇️

Trophic factors differentiate dopamine neurons vulnerable to Parkinson's disease.

Understanding the Influence of Target Acquisition on Survival, Integration, and Phenotypic Maturation of Dopamine Neurons within Stem Cell-Derived Neural Grafts in a Parkinson's Disease Model