Lista de obras - Kristine Freude - Dominio Público Uruguay

A Sox9/Fgf feed-forward loop maintains pancreatic organ identity.

artículo científico publicado en 2012

A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation

scientific journal article

Cell Type Specific Expression of Toll-Like Receptors in Human Brains and Implications in Alzheimer's Disease

artículo científico publicado en 2019

Characterization of energy and neurotransmitter metabolism in cortical glutamatergic neurons derived from human induced pluripotent stem cells: A novel approach to study metabolism in human neurons.

artículo científico publicado en 2017

Dementia, Brain Disorders and Molecular Mechanisms

artículo científico publicado en 2019

Derivation of induced pluripotent stem cells from a familial Alzheimer's disease patient carrying the L282F mutation in presenilin 1.

artículo científico publicado en 2016

Disruption of Netrin G1 by a balanced chromosome translocation in a girl with Rett syndrome.

artículo científico publicado en 2005

Essential Roles of Lactate in Müller Cell Survival and Function.

artículo científico publicado en 2018

Evaluation of porcine stem cell competence for somatic cell nuclear transfer and production of cloned animals.

artículo científico publicado en 2017

Generation of a gene-corrected isogenic control hiPSC line derived from a familial Alzheimer's disease patient carrying a L150P mutation in presenilin 1.

artículo científico publicado en 2016

Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific heterozygous mutation in CHMP2B.

artículo científico publicado en 2016

Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific homozygous mutation in CHMP2B.

artículo científico publicado en 2016

Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a L150P mutation in PSEN-1.

artículo científico publicado en 2015

Generation of induced pluripotent stem cells (iPSCs) stably expressing CRISPR-based synergistic activation mediator (SAM).

artículo científico publicado en 2016

Generation of transgene-free porcine intermediate type induced pluripotent stem cells

scientific article published on 03 December 2018

Generation of two iPSC lines with either a heterozygous V717I or a heterozygous KM670/671NL mutation in the APP gene

scientific article published on 24 December 2018

Generation of two isogenic iPSC lines with either a heterozygous or a homozygous E280A mutation in the PSEN1 gene

artículo científico publicado en 2019

Genetic Protection Modifications: Moving Beyond the Binary Distinction Between Therapy and Enhancement for Human Genome Editing

artículo científico publicado en 2019

Glutamate-glutamine homeostasis is perturbed in neurons and astrocytes derived from patient iPSC models of frontotemporal dementia

scientific article published on 14 September 2020

Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer's disease

artículo científico publicado en 2021

Identification of SSEA-1 expressing enhanced reprogramming (SEER) cells in porcine embryonic fibroblasts

artículo científico publicado en 2017

Identification of potential biomarkers in donor cows for in vitro embryo production by granulosa cell transcriptomics

artículo científico publicado en 2017

Implications of Microglia in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

scientific article published on 11 February 2019

Induced Pluripotent Stem Cells Derived from Alzheimer's Disease Patients: The Promise, the Hope and the Path Ahead.

artículo científico

Induced pluripotent stem cells throughout the animal kingdom: Availability and applications

scientific article published on 01 August 2019

Initial embryology and pluripotent stem cells in the pig--The quest for establishing the pig as a model for cell therapy.

artículo científico

Mammalian embryo comparison identifies novel pluripotency genes associated with the naïve or primed state

scientific article published on 17 August 2018

Mitochondrial Spare Respiratory Capacity Is Negatively Correlated with Nuclear Reprogramming Efficiency.

artículo científico publicado en 2016

Modeling neurodegenerative diseases with patient-derived induced pluripotent cells: Possibilities and challenges

artículo científico publicado en 2017

Modelling the neuropathology of lysosomal storage disorders through disease-specific human induced pluripotent stem cells

scientific article published on 27 April 2019

Mutations in the polyglutamine binding protein 1 gene cause X-linked mental retardation

artículo científico publicado en 2003

Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation.

artículo científico publicado en 2017

Neurosphere Based Differentiation of Human iPSC Improves Astrocyte Differentiation.

artículo científico publicado en 2015

Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors.

artículo científico publicado en 2010

Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain

scientific journal article

Oocytes, embryos and pluripotent stem cells from a biomedical perspective

scientific article published on 23 October 2019

Optimization of three-dimensional imaging on in vitro produced porcine blastocysts and chimeras for stem cell testing: a technology report

artículo científico publicado en 2015

Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B

artículo científico publicado en 2017

Systematic in vitro and in vivo characterization of Leukemia-inhibiting factor- and Fibroblast growth factor-derived porcine induced pluripotent stem cells.

artículo científico publicado en 2017

Systems Biology and Stem Cell Pluripotency: Revisiting the Discovery of Induced Pluripotent Stem Cell

artículo científico publicado en 2016

The G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes

artículo científico publicado en 2022

Toward Development of Pluripotent Porcine Stem Cells by Road Mapping Early Embryonic Development

artículo científico publicado en 2017

WebCircRNA: Classifying the Circular RNA Potential of Coding and Noncoding RNA

artículo científico publicado en 2018

Lista de obras de Kristine Freude

A Sox9/Fgf feed-forward loop maintains pancreatic organ identity.

A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation

Cell Type Specific Expression of Toll-Like Receptors in Human Brains and Implications in Alzheimer's Disease

Characterization of energy and neurotransmitter metabolism in cortical glutamatergic neurons derived from human induced pluripotent stem cells: A novel approach to study metabolism in human neurons.

Dementia, Brain Disorders and Molecular Mechanisms

Derivation of induced pluripotent stem cells from a familial Alzheimer's disease patient carrying the L282F mutation in presenilin 1.

Disruption of Netrin G1 by a balanced chromosome translocation in a girl with Rett syndrome.

Essential Roles of Lactate in Müller Cell Survival and Function.

Evaluation of porcine stem cell competence for somatic cell nuclear transfer and production of cloned animals.

Generation of a gene-corrected isogenic control hiPSC line derived from a familial Alzheimer's disease patient carrying a L150P mutation in presenilin 1.

Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific heterozygous mutation in CHMP2B.

Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific homozygous mutation in CHMP2B.

Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a L150P mutation in PSEN-1.

Generation of induced pluripotent stem cells (iPSCs) stably expressing CRISPR-based synergistic activation mediator (SAM).

Generation of transgene-free porcine intermediate type induced pluripotent stem cells

Generation of two iPSC lines with either a heterozygous V717I or a heterozygous KM670/671NL mutation in the APP gene

Generation of two isogenic iPSC lines with either a heterozygous or a homozygous E280A mutation in the PSEN1 gene

Genetic Protection Modifications: Moving Beyond the Binary Distinction Between Therapy and Enhancement for Human Genome Editing

Glutamate-glutamine homeostasis is perturbed in neurons and astrocytes derived from patient iPSC models of frontotemporal dementia

Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer's disease

Identification of SSEA-1 expressing enhanced reprogramming (SEER) cells in porcine embryonic fibroblasts

Identification of potential biomarkers in donor cows for in vitro embryo production by granulosa cell transcriptomics

Implications of Microglia in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

Induced Pluripotent Stem Cells Derived from Alzheimer's Disease Patients: The Promise, the Hope and the Path Ahead.

Induced pluripotent stem cells throughout the animal kingdom: Availability and applications

Initial embryology and pluripotent stem cells in the pig--The quest for establishing the pig as a model for cell therapy.

Mammalian embryo comparison identifies novel pluripotency genes associated with the naïve or primed state

Mitochondrial Spare Respiratory Capacity Is Negatively Correlated with Nuclear Reprogramming Efficiency.

Modeling neurodegenerative diseases with patient-derived induced pluripotent cells: Possibilities and challenges

Modelling the neuropathology of lysosomal storage disorders through disease-specific human induced pluripotent stem cells

Mutations in the polyglutamine binding protein 1 gene cause X-linked mental retardation

Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation.

Neurosphere Based Differentiation of Human iPSC Improves Astrocyte Differentiation.

Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors.

Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain

Oocytes, embryos and pluripotent stem cells from a biomedical perspective

Optimization of three-dimensional imaging on in vitro produced porcine blastocysts and chimeras for stem cell testing: a technology report

Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B

Systematic in vitro and in vivo characterization of Leukemia-inhibiting factor- and Fibroblast growth factor-derived porcine induced pluripotent stem cells.

Systems Biology and Stem Cell Pluripotency: Revisiting the Discovery of Induced Pluripotent Stem Cell

The G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes

Toward Development of Pluripotent Porcine Stem Cells by Road Mapping Early Embryonic Development

WebCircRNA: Classifying the Circular RNA Potential of Coding and Noncoding RNA