Lista de obras - Alexander Anderson - Dominio Público Uruguay

A filter-flow perspective of haematogenous metastasis offers a non-genetic paradigm for personalised cancer therapy.

artículo científico publicado en 2014

A hybrid mathematical model of solid tumour invasion: the importance of cell adhesion

scientific article published on 21 March 2005

A mathematical model of tumour self-seeding reveals secondary metastatic deposits as drivers of primary tumour growth.

artículo científico publicado en 2013

A novel 'sandwich' assay for quantifying chemo-regulated cell migration within 3-dimensional matrices: wound healing cytokines exhibit distinct motogenic activities compared to the transmembrane assay.

artículo científico publicado en 2006

An individual based model of rippling movement in a myxobacteria population

artículo científico publicado en 2005

Applying a patient-specific bio-mathematical model of glioma growth to develop virtual [18F]-FMISO-PET images.

artículo científico publicado en 2011

Big Bang and context-driven collapse

artículo científico publicado en 2015

Bridging population and tissue scale tumor dynamics: a new paradigm for understanding differences in tumor growth and metastatic disease

artículo científico publicado en 2014

Bridging scales in cancer progression: mapping genotype to phenotype using neural networks

artículo científico publicado en 2015

Cellular modeling of cancer invasion: Integration of in silico and in vitro approaches ⬇️

artículo científico publicado el 1 de febrero de 2012

Clonal hematopoiesis of indeterminate potential and its impact on patient trajectories after stem cell transplantation

artículo científico publicado en 2019

Computational investigation of intrinsic and extrinsic mechanisms underlying the formation of carcinoma ⬇️

artículo científico publicado el 24 de noviembre de 2010

Continuous and discrete mathematical models of tumor-induced angiogenesis.

artículo científico publicado en 1998

Dissecting targeted therapy resistance: Integrating models to quantify environment mediated drug resistance

EvoFreq: visualization of the Evolutionary Frequencies of sequence and model data

scientific article published on 16 December 2019

Evolution of cell motility in an individual-based model of tumour growth.

artículo científico publicado en 2009

Evolution of intratumoral phenotypic heterogeneity: the role of trait inheritance.

artículo científico publicado en 2013

Evolutionary dynamics of neoantigens in growing tumors

artículo científico publicado en 2020

Evolving homeostatic tissue using genetic algorithms.

artículo científico publicado en 2011

Exploiting ecological principles to better understand cancer progression and treatment.

artículo científico publicado en 2013

Exploiting evolution to treat drug resistance: combination therapy and the double bind

artículo científico publicado en 2012

Fibroblasts contribute to melanoma tumor growth and drug resistance.

artículo científico publicado en 2011

From cells to tissue: How cell scale heterogeneity impacts glioblastoma growth and treatment response

artículo científico publicado en 2020

Front instabilities and invasiveness of simulated avascular tumors ⬇️

artículo científico publicado en 2009

Histoecology: Applying Ecological Principles and Approaches to Describe and Predict Tumor Ecosystem Dynamics Across Space and Time

artículo científico publicado en 2020

Hybrid Automata Library: A flexible platform for hybrid modeling with real-time visualization

scientific article published on 10 March 2020

Hybrid models of tumor growth.

artículo científico publicado en 2011

IgA transcytosis and antigen recognition govern ovarian cancer immunity

artículo científico publicado en 2021

Immune interconnectivity of anatomically distant tumors as a potential mediator of systemic responses to local therapy.

artículo científico publicado en 2018

Immunosuppressive niche engineering at the onset of human colorectal cancer

artículo científico publicado en 2022

Impact of metabolic heterogeneity on tumor growth, invasion, and treatment outcomes. ⬇️

artículo científico publicado en 2015

In silico analysis suggests differential response to bevacizumab and radiation combination therapy in newly diagnosed glioblastoma.

artículo científico publicado en 2015

Inhibition of autophagy enhances the effects of the AKT inhibitor MK-2206 when combined with paclitaxel and carboplatin in BRAF wild-type melanoma.

artículo científico publicado en 2014

Investigating prostate cancer tumour–stroma interactions: clinical and biological insights from an evolutionary game ⬇️

artículo científico publicado el 3 de enero de 2012

Mathematical Oncology

artículo científico publicado en 2018

Mathematical modeling of tumor-induced angiogenesis

scientific article published on 01 January 2006

Mathematical modelling of flow through vascular networks: implications for tumour-induced angiogenesis and chemotherapy strategies.

artículo científico publicado en 2002

Mathematical modelling of radiotherapy strategies for early breast cancer.

artículo científico publicado en 2005

Mathematical modelling of tumour-induced angiogenesis: network growth and structure.

artículo científico publicado en 2004

Mistic: An open-source multiplexed image t-SNE viewer

artículo científico publicado en 2022

Model genotype-phenotype mappings and the algorithmic structure of evolution

scientific article published on 06 November 2019

Modelling the spatio-temporal dynamics of multi-species host-parasitoid interactions: heterogeneous patterns and ecological implications.

artículo científico publicado en 2006

Multidrug Cancer Therapy in Metastatic Castrate-Resistant Prostate Cancer: An Evolution-Based Strategy

scientific article published on 16 April 2019

Multiscale modelling and nonlinear simulation of vascular tumour growth.

artículo científico publicado en 2008

Nest expansion assay: a cancer systems biology approach to in vitro invasion measurements

artículo científico publicado en 2009

Normal tissue architecture determines the evolutionary course of cancer

artículo científico publicado en 2021

PTEN loss confers BRAF inhibitor resistance to melanoma cells through the suppression of BIM expression

artículo científico publicado en 2011

Paradoxical dependencies of tumor dormancy and progression on basic cell kinetics

artículo científico publicado en 2009

Searching for Goldilocks: How evolution and ecology can help uncover more effective patient-specific chemotherapies

scientific article published on 15 September 2020

Senescent fibroblasts in melanoma initiation and progression: an integrated theoretical, experimental, and clinical approach

artículo científico publicado en 2013

Sex differences in health and disease: A review of biological sex differences relevant to cancer with a spotlight on glioma

artículo científico publicado en 2020

State of the art in computational modelling of cancer ⬇️

artículo científico publicado el 26 de diciembre de 2011

Steering Evolution with Sequential Therapy to Prevent the Emergence of Bacterial Antibiotic Resistance

artículo científico publicado en 2015

Stochasticity in the Genotype-Phenotype Map: Implications for the Robustness and Persistence of Bet-Hedging

artículo científico publicado en 2016

Stromal reactivity differentially drives tumour cell evolution and prostate cancer progression

scientific article published on 11 May 2020

Systematic Screening of Chemokines to Identify Candidates to Model and Create Ectopic Lymph Node Structures for Cancer Immunotherapy.

artículo científico publicado en 2017

The Goldilocks Window of Personalized Chemotherapy: Getting the Immune Response Just Right

scientific article published on 06 August 2019

The biology underlying molecular imaging in oncology: from genome to anatome and back again

artículo científico publicado en 2010

The evolutionary landscape of colorectal tumorigenesis ⬇️

scientific article published on 31 August 2018

The impact of proliferation-migration tradeoffs on phenotypic evolution in cancer

scientific article published on 20 February 2019

The role of memory in non-genetic inheritance and its impact on cancer treatment resistance

artículo científico publicado en 2021

Towards Multidrug Adaptive Therapy

scientific article published on 16 January 2020

Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment.

artículo científico publicado en 2006

Turnover modulates the need for a cost of resistance in adaptive therapy

artículo científico publicado en 2020

Visualisation of the numerical solution of partial differential equation systems in three space dimensions and its importance for mathematical models in biology.

artículo científico publicado en 2006

Lista de obras de Alexander Anderson

A filter-flow perspective of haematogenous metastasis offers a non-genetic paradigm for personalised cancer therapy.

A hybrid mathematical model of solid tumour invasion: the importance of cell adhesion

A mathematical model of tumour self-seeding reveals secondary metastatic deposits as drivers of primary tumour growth.

A novel 'sandwich' assay for quantifying chemo-regulated cell migration within 3-dimensional matrices: wound healing cytokines exhibit distinct motogenic activities compared to the transmembrane assay.

An individual based model of rippling movement in a myxobacteria population

Applying a patient-specific bio-mathematical model of glioma growth to develop virtual [18F]-FMISO-PET images.

Big Bang and context-driven collapse

Bridging population and tissue scale tumor dynamics: a new paradigm for understanding differences in tumor growth and metastatic disease

Bridging scales in cancer progression: mapping genotype to phenotype using neural networks

Cellular modeling of cancer invasion: Integration of in silico and in vitro approaches ⬇️

Clonal hematopoiesis of indeterminate potential and its impact on patient trajectories after stem cell transplantation

Computational investigation of intrinsic and extrinsic mechanisms underlying the formation of carcinoma ⬇️

Continuous and discrete mathematical models of tumor-induced angiogenesis.

Dissecting targeted therapy resistance: Integrating models to quantify environment mediated drug resistance

EvoFreq: visualization of the Evolutionary Frequencies of sequence and model data

Evolution of cell motility in an individual-based model of tumour growth.

Evolution of intratumoral phenotypic heterogeneity: the role of trait inheritance.

Evolutionary dynamics of neoantigens in growing tumors

Evolving homeostatic tissue using genetic algorithms.

Exploiting ecological principles to better understand cancer progression and treatment.

Exploiting evolution to treat drug resistance: combination therapy and the double bind

Fibroblasts contribute to melanoma tumor growth and drug resistance.

From cells to tissue: How cell scale heterogeneity impacts glioblastoma growth and treatment response

Front instabilities and invasiveness of simulated avascular tumors ⬇️

Histoecology: Applying Ecological Principles and Approaches to Describe and Predict Tumor Ecosystem Dynamics Across Space and Time

Hybrid Automata Library: A flexible platform for hybrid modeling with real-time visualization

Hybrid models of tumor growth.

IgA transcytosis and antigen recognition govern ovarian cancer immunity

Immune interconnectivity of anatomically distant tumors as a potential mediator of systemic responses to local therapy.

Immunosuppressive niche engineering at the onset of human colorectal cancer

Impact of metabolic heterogeneity on tumor growth, invasion, and treatment outcomes. ⬇️

In silico analysis suggests differential response to bevacizumab and radiation combination therapy in newly diagnosed glioblastoma.

Inhibition of autophagy enhances the effects of the AKT inhibitor MK-2206 when combined with paclitaxel and carboplatin in BRAF wild-type melanoma.

Investigating prostate cancer tumour–stroma interactions: clinical and biological insights from an evolutionary game ⬇️

Mathematical Oncology

Mathematical modeling of tumor-induced angiogenesis

Mathematical modelling of flow through vascular networks: implications for tumour-induced angiogenesis and chemotherapy strategies.

Mathematical modelling of radiotherapy strategies for early breast cancer.

Mathematical modelling of tumour-induced angiogenesis: network growth and structure.

Mistic: An open-source multiplexed image t-SNE viewer

Model genotype-phenotype mappings and the algorithmic structure of evolution

Modelling the spatio-temporal dynamics of multi-species host-parasitoid interactions: heterogeneous patterns and ecological implications.

Multidrug Cancer Therapy in Metastatic Castrate-Resistant Prostate Cancer: An Evolution-Based Strategy

Multiscale modelling and nonlinear simulation of vascular tumour growth.

Nest expansion assay: a cancer systems biology approach to in vitro invasion measurements

Normal tissue architecture determines the evolutionary course of cancer

PTEN loss confers BRAF inhibitor resistance to melanoma cells through the suppression of BIM expression

Paradoxical dependencies of tumor dormancy and progression on basic cell kinetics

Searching for Goldilocks: How evolution and ecology can help uncover more effective patient-specific chemotherapies

Senescent fibroblasts in melanoma initiation and progression: an integrated theoretical, experimental, and clinical approach

Sex differences in health and disease: A review of biological sex differences relevant to cancer with a spotlight on glioma

State of the art in computational modelling of cancer ⬇️

Steering Evolution with Sequential Therapy to Prevent the Emergence of Bacterial Antibiotic Resistance

Stochasticity in the Genotype-Phenotype Map: Implications for the Robustness and Persistence of Bet-Hedging

Stromal reactivity differentially drives tumour cell evolution and prostate cancer progression

Systematic Screening of Chemokines to Identify Candidates to Model and Create Ectopic Lymph Node Structures for Cancer Immunotherapy.

The Goldilocks Window of Personalized Chemotherapy: Getting the Immune Response Just Right

The biology underlying molecular imaging in oncology: from genome to anatome and back again

The evolutionary landscape of colorectal tumorigenesis ⬇️

The impact of proliferation-migration tradeoffs on phenotypic evolution in cancer

The role of memory in non-genetic inheritance and its impact on cancer treatment resistance

Towards Multidrug Adaptive Therapy

Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment.

Turnover modulates the need for a cost of resistance in adaptive therapy

Visualisation of the numerical solution of partial differential equation systems in three space dimensions and its importance for mathematical models in biology.