Lista de obras - Robert Sebra - Dominio Público Uruguay

A Complete Genome Screening Program of Clinical Methicillin-Resistant Staphylococcus aureus Isolates Identifies the Origin and Progression of a Neonatal Intensive Care Unit Outbreak

scientific article published on 22 November 2019

A Novel Framework for Characterizing Genomic Haplotype Diversity in the Human Immunoglobulin Heavy Chain Locus

artículo científico publicado en 2020

A hybrid approach for the automated finishing of bacterial genomes

artículo científico publicado en 2012

A next generation sequencing based approach to identify extracellular vesicle mediated mRNA transfers between cells

artículo científico publicado en 2017

A personalized platform identifies trametinib plus zoledronate for a patient with KRAS-mutant metastatic colorectal cancer

scientific article published on 22 May 2019

A physical and genetic map of identifies extensive rearrangement at the THC/CBD acid synthase locus

artículo científico publicado en 2018

An integrated map of structural variation in 2,504 human genomes

artículo científico publicado en 2015

Analysis of the Aedes albopictus C6/36 genome provides insight into cell line utility for viral propagation

artículo científico publicado en 2018

Application of Single-Cell Sequencing to Immunotherapy

scientific article published on 09 September 2020

Assembly and diploid architecture of an individual human genome via single-molecule technologies

artículo científico publicado en 2015

Author Correction: Sampling the host response to SARS-CoV-2 in hospitals under siege

scientific article published on 21 August 2020

Blurred Molecular Epidemiological Lines Between the Two Dominant Methicillin-Resistant Staphylococcus aureus Clones

artículo científico publicado en 2019

COVID-19: Staging of a New Disease

artículo científico publicado en 2020

Capturing pairwise and multi-way chromosomal conformations using chromosomal walks.

artículo científico publicado en 2016

Cell-to-Cell Variation in Defective Virus Expression and Effects on Host Responses during Influenza Virus Infection

scientific article published on 14 January 2020

Characterizing and Overriding the Structural Mechanism of the Quizartinib-Resistant FLT3 "Gatekeeper" F691L Mutation with PLX3397

artículo científico publicado en 2015

Chromosomal Integration of the Klebsiella pneumoniae Carbapenemase Gene, blaKPC, in Klebsiella Species Is Elusive but Not Rare

artículo científico publicado en 2016

Comparative analysis of tandem repeats from hundreds of species reveals unique insights into centromere evolution

artículo científico publicado en 2013

Comparative genomic analysis of driver mutations in matched primary and recurrent meningiomas.

artículo científico publicado en 2019

Complete Genome Sequence of KPC-Producing Klebsiella pneumoniae Strain CAV1193.

artículo científico publicado en 2016

Complete Sequencing of Plasmids Containing blaOXA-163 and blaOXA-48 in Escherichia coli Sequence Type 131.

artículo científico publicado en 2016

Cytogenomic identification and long-read single molecule real-time (SMRT) sequencing of a Bardet-Biedl Syndrome 9 (BBS9) deletion

artículo científico publicado en 2018

Cytotoxic lymphocytes are dysregulated in multisystem inflammatory syndrome in children

scientific article published on 02 September 2020

DNA sequencing at ultra-high fidelity

artículo científico publicado en 2017

Detection of endometrial precancer by a targeted gynecologic cancer liquid biopsy

Development and clinical application of an integrative genomic approach to personalized cancer therapy

artículo científico publicado en 2016

Diversity of peripheral blood human NK cells identified by single-cell RNA sequencing

scientific article published on 01 April 2020

Don't overlook the little guy: An evaluation of the frequency of small plasmids co-conjugating with larger carbapenemase gene containing plasmids

scientific article published on 27 March 2019

Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors

scientific article published on 01 November 2019

Emergence and Evolution of Multidrug-Resistant Klebsiella pneumoniae with both blaKPC and blaCTX-M Integrated in Chromosome

artículo científico publicado en 2017

Epigenetic Switch Driven by DNA Inversions Dictates Phase Variation in Streptococcus pneumoniae.

artículo científico publicado en 2016

Epigenetic preconditioning with decitabine sensitizes glioblastoma to temozolomide via induction of MLH1

scientific article published on 19 March 2020

Epigenomic characterization of Clostridioides difficile finds a conserved DNA methyltransferase that mediates sporulation and pathogenesis

scientific article published on 25 November 2019

Evolution and Transmission of Carbapenem-Resistant Klebsiella pneumoniae Expressing the blaOXA-232 Gene During an Institutional Outbreak Associated With Endoscopic Retrograde Cholangiopancreatography

artículo científico publicado en 2017

Evolution of hypervirulence by a MRSA clone through acquisition of a transposable element

artículo científico publicado en 2014

Evolutionary History of the Global Emergence of the Escherichia coli Epidemic Clone ST131

artículo científico publicado en 2016

Evolutionary history of the global emergence of the Escherichia coli epidemic clone ST131

scholarly article published 6 November 2015

Ex vivo human HSC expansion requires coordination of cellular reprogramming with mitochondrial remodeling and p53 activation

Extensive sequencing of seven human genomes to characterize benchmark reference materials

artículo científico publicado en 2016

Familial Hypercholesterolemia in a Healthy Elderly Population

scientific article published on 10 June 2020

First Report of blaIMP-14 on a Plasmid Harboring Multiple Drug Resistance Genes in Escherichia coli Sequence Type 131.

artículo científico publicado en 2016

GENE-20. USE OF DECITABINE TO ALTER PATTERNS OF TREATMENT-INDUCED MUTAGENESIS IN GLIOBLASTOMA

artículo científico publicado en 2017

Gaining comprehensive biological insight into the transcriptome by performing a broad-spectrum RNA-seq analysis

artículo científico publicado en 2017

Genetic associations with clozapine-induced myocarditis in patients with schizophrenia

artículo científico publicado en 2020

Genetic resilience to Alzheimer's disease in APOE ε4 homozygotes: A systematic review

artículo científico publicado en 2019

Genome Plasticity of -Defective Staphylococcus aureus during Clinical Infection

scholarly article published by Deena R Altman in 2018

Genome Sequence of Bacterial Interference Strain Staphylococcus aureus 502A.

artículo científico publicado en 2014

Genome-Wide Biases in the Rate and Molecular Spectrum of Spontaneous Mutations in Vibrio cholerae and Vibrio fischeri

artículo científico publicado en 2016

Genomic Analysis of Uterine Lavage Fluid Detects Early Endometrial Cancers and Reveals a Prevalent Landscape of Driver Mutations in Women without Histopathologic Evidence of Cancer: A Prospective Cross-Sectional Study.

artículo científico publicado en 2016

Genomic confirmation of vancomycin-resistant Enterococcus transmission from deceased donor to liver transplant recipient

artículo científico publicado en 2017

Genomic epidemiology of complex, multi-species, plasmid-borne bla KPC carbapenemase in Enterobacterales in the UK, 2009-2014

artículo científico publicado en 2020

Genomic epidemiology of global Klebsiella pneumoniae carbapenemase (KPC)-producing E. coli

Genomic profiling reveals mutational landscape in parathyroid carcinomas

artículo científico publicado en 2017

HIV-1 Infection of Primary CD4+ T Cells Regulates the Expression of Specific Human Endogenous Retrovirus HERV-K (HML-2) Elements

artículo científico publicado en 2017

HIV-1 interacts with human endogenous retrovirus K (HML-2) envelopes derived from human primary lymphocytes

artículo científico publicado en 2014

High-coverage, long-read sequencing of Han Chinese trio reference samples.

artículo científico publicado en 2019

High-density single cell mRNA sequencing to characterize circulating tumor cells in hepatocellular carcinoma

artículo científico publicado en 2018

IMMU-60. MAPPING TUMORAL AND IMMUNE HETEROGENEITY IN PD-1 RESPONSIVE GLIOBLASTOMA

Identification of a novel RASD1 somatic mutation in a USP8-mutated corticotroph adenoma.

artículo científico publicado en 2017

In Reply: Retention of ATRX and DAXX Expression in Meningiomas

scientific article published on 01 February 2020

Influenza virus infection causes global RNAPII termination defects

Inhibition of the Nuclear Export Receptor XPO1 as a Therapeutic Target for Platinum-Resistant Ovarian Cancer

artículo científico publicado en 2016

Integrated Transcriptome and Network Analysis Reveals Spatiotemporal Dynamics of Calvarial Suturogenesis

scientific article published on 01 July 2020

Interpretable and context-free deconvolution of multi-scale whole transcriptomic data with UniCell deconvolve

artículo científico publicado en 2023

Intrahost dynamics of antiviral resistance in influenza A virus reflect complex patterns of segment linkage, reassortment, and natural selection

artículo científico publicado en 2015

Intratumoral heterogeneity and clonal evolution in liver cancer

artículo científico publicado en 2020

Introductions and early spread of SARS-CoV-2 in the New York City area

artículo científico publicado en 2020

Introductions and early spread of SARS-CoV-2 in the New York City area

artículo científico publicado en 2020

Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae at a single institution: insights into endemicity from whole-genome sequencing

artículo científico publicado en 2015

Klebsiella quasipneumoniae Provides a Window into Carbapenemase Gene Transfer, Plasmid Rearrangements, and Patient Interactions with the Hospital Environment.

artículo científico publicado en 2019

Limited Mitochondrial Activity Coupled With Strong Expression of CD34, CD90 and EPCR Determines the Functional Fitness of <i>ex vivo</i> Expanded Human Hematopoietic Stem Cells

artículo científico publicado en 2020

Long-Read Single Molecule Real-Time Full Gene Sequencing of Cytochrome P450-2D6.

artículo científico publicado en 2015

Mapping and characterizing N6-methyladenine in eukaryotic genomes using single-molecule real-time sequencing

Mce3R Stress-Resistance Pathway Is Vulnerable to Small-Molecule Targeting That Improves Tuberculosis Drug Activities

artículo científico publicado en 2019

Medically actionable pathogenic variants in a population of 13,131 healthy elderly individuals

artículo científico publicado en 2020

Metagenomic binning and association of plasmids with bacterial host genomes using DNA methylation.

artículo científico publicado en 2017

Methicillin-Susceptible, Vancomycin-Resistant Staphylococcus aureus, Brazil

artículo científico publicado en 2015

NF2 mutation status and tumor mutational burden correlate with immune cell infiltration in meningiomas

artículo científico publicado en 2020

Negative feedback control of neuronal activity by microglia

scientific article published on 30 September 2020

Nested Russian Doll-Like Genetic Mobility Drives Rapid Dissemination of the Carbapenem Resistance Gene blaKPC

artículo científico publicado en 2016

Nested Russian Doll-like Genetic Mobility Drives Rapid Dissemination of the Carbapenem Resistance GeneblaKPC

article

Neuronal impact of patient-specific aberrant NRXN1α splicing

scientific article published on 29 November 2019

ORF Capture-Seq as a versatile method for targeted identification of full-length isoforms

scientific article published on 11 May 2020

Origins of the E. coli strain causing an outbreak of hemolytic-uremic syndrome in Germany

artículo científico publicado en 2011

Parallel Epidemics of Community-Associated Methicillin-Resistant Staphylococcus aureus USA300 Infection in North and South America

artículo científico publicado en 2015

PathoSPOT genomic epidemiology reveals under-the-radar nosocomial outbreaks

artículo científico publicado en 2020

Pathophysiology of SARS-CoV-2: targeting of endothelial cells renders a complex disease with thrombotic microangiopathy and aberrant immune response. The Mount Sinai COVID-19 autopsy experience

artículo científico publicado en 2020

Peritumoral edema correlates with mutational burden in meningiomas

scientific article published on 12 August 2020

Personalized Circulating Tumor DNA Biomarkers Dynamically Predict Treatment Response and Survival In Gynecologic Cancers

artículo científico publicado en 2015

Prevalence and disease predisposition of p.A91V perforin in an aged population of European ancestry

scientific article published on 01 February 2020

Prospective Isolation and Comparison of Human Germinal Matrix and Glioblastoma EGFR+ Populations with Stem Cell Properties

artículo científico publicado en 2017

Quantifying influenza virus diversity and transmission in humans

artículo científico publicado en 2016

Quantitative and multiplexed DNA methylation analysis using long-read single-molecule real-time bisulfite sequencing (SMRT-BS).

artículo científico publicado en 2015

Real Time Investigation of a large Nosocomial Influenza A Outbreak Informed by Genomic Epidemiology

artículo científico publicado en 2020

Real-Time Investigation of a Large Nosocomial Influenza A Outbreak Informed by Genomic Epidemiology

artículo científico publicado en 2020

Real-time DNA sequencing from single polymerase molecules

artículo científico publicado en 2009

Recurrent IDH Mutations in High-Grade Meningioma

scientific article published on 17 March 2020

Resistance to Ceftazidime-Avibactam Is Due to Transposition of KPC in a Porin-Deficient Strain of Klebsiella pneumoniae with Increased Efflux Activity

artículo científico publicado en 2017

SARS-CoV-2 Transmission among Marine Recruits during Quarantine

artículo científico publicado en 2020

STK11 mutation status is associated with decreased survival in meningiomas

scientific article published on 07 April 2020

Sampling the host response to SARS-CoV-2 in hospitals under siege

artículo científico publicado en 2020

Sequential evolution of virulence and resistance during clonal spread of community-acquired methicillin-resistant

artículo científico publicado en 2019

Single cell profiling of peanut-responsive T cells in peanut allergic subjects reveals heterogeneous effector Th2 subsets

artículo científico publicado en 2018

Single molecule-level detection and long read-based phasing of epigenetic variations in bacterial methylomes

artículo científico publicado en 2015

Single-Molecule Real-Time (SMRT) Full-Length RNA-Sequencing Reveals Novel and Distinct mRNA Isoforms in Human Bone Marrow Cell Subpopulations.

artículo científico publicado en 2019

The Complete Genome Sequence of the Emerging Pathogen Mycobacterium haemophilum Explains Its Unique Culture Requirements

artículo científico publicado en 2015

The Mce3R stress-resistance pathway is vulnerable to small-molecule targeting that improves tuberculosis drug activities

The PsychENCODE project

artículo científico publicado en 2015

The genetic basis of emerging vancomycin, linezolid, and daptomycin heteroresistance in a case of persistent Enterococcus faecium bacteremia

artículo científico publicado en 2018

The genome of a subterrestrial nematode reveals adaptations to heat

scientific article published on 21 November 2019

Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models

scientific article published on 01 December 2020

Treatment-associated TP53 DNA-binding domain missense mutations in the pathogenesis of secondary gliosarcoma

artículo científico publicado en 2017

Tumoral and immune heterogeneity in an anti-PD-1-responsive glioblastoma: a case study

scientific article published on 01 April 2020

USP8 and TP53 drivers are associated with CNV in a corticotroph adenoma cohort enriched for aggressive tumors

artículo científico publicado en 2020

Use of Multiple Sequencing Technologies To Produce a High-Quality Genome of the Fungus Pseudogymnoascus destructans, the Causative Agent of Bat White-Nose Syndrome

artículo científico publicado en 2016

Using single-cell multiple omics approaches to resolve tumor heterogeneity

artículo científico publicado en 2017

Whole-genome sequencing identifies emergence of a quinolone resistance mutation in a case of Stenotrophomonas maltophilia bacteremia.

artículo científico publicado en 2015

Lista de obras de Robert Sebra

A Complete Genome Screening Program of Clinical Methicillin-Resistant Staphylococcus aureus Isolates Identifies the Origin and Progression of a Neonatal Intensive Care Unit Outbreak

A Novel Framework for Characterizing Genomic Haplotype Diversity in the Human Immunoglobulin Heavy Chain Locus

A hybrid approach for the automated finishing of bacterial genomes

A next generation sequencing based approach to identify extracellular vesicle mediated mRNA transfers between cells

A personalized platform identifies trametinib plus zoledronate for a patient with KRAS-mutant metastatic colorectal cancer

A physical and genetic map of identifies extensive rearrangement at the THC/CBD acid synthase locus

An integrated map of structural variation in 2,504 human genomes

Analysis of the Aedes albopictus C6/36 genome provides insight into cell line utility for viral propagation

Application of Single-Cell Sequencing to Immunotherapy

Assembly and diploid architecture of an individual human genome via single-molecule technologies

Author Correction: Sampling the host response to SARS-CoV-2 in hospitals under siege

Blurred Molecular Epidemiological Lines Between the Two Dominant Methicillin-Resistant Staphylococcus aureus Clones

COVID-19: Staging of a New Disease

Capturing pairwise and multi-way chromosomal conformations using chromosomal walks.

Cell-to-Cell Variation in Defective Virus Expression and Effects on Host Responses during Influenza Virus Infection

Characterizing and Overriding the Structural Mechanism of the Quizartinib-Resistant FLT3 "Gatekeeper" F691L Mutation with PLX3397

Chromosomal Integration of the Klebsiella pneumoniae Carbapenemase Gene, blaKPC, in Klebsiella Species Is Elusive but Not Rare

Comparative analysis of tandem repeats from hundreds of species reveals unique insights into centromere evolution

Comparative genomic analysis of driver mutations in matched primary and recurrent meningiomas.

Complete Genome Sequence of KPC-Producing Klebsiella pneumoniae Strain CAV1193.

Complete Sequencing of Plasmids Containing blaOXA-163 and blaOXA-48 in Escherichia coli Sequence Type 131.

Cytogenomic identification and long-read single molecule real-time (SMRT) sequencing of a Bardet-Biedl Syndrome 9 (BBS9) deletion

Cytotoxic lymphocytes are dysregulated in multisystem inflammatory syndrome in children

DNA sequencing at ultra-high fidelity

Detection of endometrial precancer by a targeted gynecologic cancer liquid biopsy

Development and clinical application of an integrative genomic approach to personalized cancer therapy

Diversity of peripheral blood human NK cells identified by single-cell RNA sequencing

Don't overlook the little guy: An evaluation of the frequency of small plasmids co-conjugating with larger carbapenemase gene containing plasmids

Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors

Emergence and Evolution of Multidrug-Resistant Klebsiella pneumoniae with both blaKPC and blaCTX-M Integrated in Chromosome

Epigenetic Switch Driven by DNA Inversions Dictates Phase Variation in Streptococcus pneumoniae.

Epigenetic preconditioning with decitabine sensitizes glioblastoma to temozolomide via induction of MLH1

Epigenomic characterization of Clostridioides difficile finds a conserved DNA methyltransferase that mediates sporulation and pathogenesis

Evolution and Transmission of Carbapenem-Resistant Klebsiella pneumoniae Expressing the blaOXA-232 Gene During an Institutional Outbreak Associated With Endoscopic Retrograde Cholangiopancreatography

Evolution of hypervirulence by a MRSA clone through acquisition of a transposable element

Evolutionary History of the Global Emergence of the Escherichia coli Epidemic Clone ST131

Evolutionary history of the global emergence of the Escherichia coli epidemic clone ST131

Ex vivo human HSC expansion requires coordination of cellular reprogramming with mitochondrial remodeling and p53 activation

Extensive sequencing of seven human genomes to characterize benchmark reference materials

Familial Hypercholesterolemia in a Healthy Elderly Population

First Report of blaIMP-14 on a Plasmid Harboring Multiple Drug Resistance Genes in Escherichia coli Sequence Type 131.

GENE-20. USE OF DECITABINE TO ALTER PATTERNS OF TREATMENT-INDUCED MUTAGENESIS IN GLIOBLASTOMA

Gaining comprehensive biological insight into the transcriptome by performing a broad-spectrum RNA-seq analysis

Genetic associations with clozapine-induced myocarditis in patients with schizophrenia

Genetic resilience to Alzheimer's disease in APOE ε4 homozygotes: A systematic review

Genome Plasticity of -Defective Staphylococcus aureus during Clinical Infection

Genome Sequence of Bacterial Interference Strain Staphylococcus aureus 502A.

Genome-Wide Biases in the Rate and Molecular Spectrum of Spontaneous Mutations in Vibrio cholerae and Vibrio fischeri

Genomic Analysis of Uterine Lavage Fluid Detects Early Endometrial Cancers and Reveals a Prevalent Landscape of Driver Mutations in Women without Histopathologic Evidence of Cancer: A Prospective Cross-Sectional Study.

Genomic confirmation of vancomycin-resistant Enterococcus transmission from deceased donor to liver transplant recipient

Genomic epidemiology of complex, multi-species, plasmid-borne bla KPC carbapenemase in Enterobacterales in the UK, 2009-2014

Genomic epidemiology of global Klebsiella pneumoniae carbapenemase (KPC)-producing E. coli

Genomic profiling reveals mutational landscape in parathyroid carcinomas

HIV-1 Infection of Primary CD4+ T Cells Regulates the Expression of Specific Human Endogenous Retrovirus HERV-K (HML-2) Elements

HIV-1 interacts with human endogenous retrovirus K (HML-2) envelopes derived from human primary lymphocytes

High-coverage, long-read sequencing of Han Chinese trio reference samples.

High-density single cell mRNA sequencing to characterize circulating tumor cells in hepatocellular carcinoma

IMMU-60. MAPPING TUMORAL AND IMMUNE HETEROGENEITY IN PD-1 RESPONSIVE GLIOBLASTOMA

Identification of a novel RASD1 somatic mutation in a USP8-mutated corticotroph adenoma.

In Reply: Retention of ATRX and DAXX Expression in Meningiomas

Influenza virus infection causes global RNAPII termination defects

Inhibition of the Nuclear Export Receptor XPO1 as a Therapeutic Target for Platinum-Resistant Ovarian Cancer

Integrated Transcriptome and Network Analysis Reveals Spatiotemporal Dynamics of Calvarial Suturogenesis

Interpretable and context-free deconvolution of multi-scale whole transcriptomic data with UniCell deconvolve

Intrahost dynamics of antiviral resistance in influenza A virus reflect complex patterns of segment linkage, reassortment, and natural selection

Intratumoral heterogeneity and clonal evolution in liver cancer

Introductions and early spread of SARS-CoV-2 in the New York City area

Introductions and early spread of SARS-CoV-2 in the New York City area

Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae at a single institution: insights into endemicity from whole-genome sequencing

Klebsiella quasipneumoniae Provides a Window into Carbapenemase Gene Transfer, Plasmid Rearrangements, and Patient Interactions with the Hospital Environment.

Limited Mitochondrial Activity Coupled With Strong Expression of CD34, CD90 and EPCR Determines the Functional Fitness of <i>ex vivo</i> Expanded Human Hematopoietic Stem Cells

Long-Read Single Molecule Real-Time Full Gene Sequencing of Cytochrome P450-2D6.

Mapping and characterizing N6-methyladenine in eukaryotic genomes using single-molecule real-time sequencing

Mce3R Stress-Resistance Pathway Is Vulnerable to Small-Molecule Targeting That Improves Tuberculosis Drug Activities

Medically actionable pathogenic variants in a population of 13,131 healthy elderly individuals

Metagenomic binning and association of plasmids with bacterial host genomes using DNA methylation.

Methicillin-Susceptible, Vancomycin-Resistant Staphylococcus aureus, Brazil

NF2 mutation status and tumor mutational burden correlate with immune cell infiltration in meningiomas

Negative feedback control of neuronal activity by microglia