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Lista de obras de James D Orth

A novel endocytic mechanism of epidermal growth factor receptor sequestration and internalization

artículo científico publicado en 2006

Actin and Arf1-dependent recruitment of a cortactin-dynamin complex to the Golgi regulates post-Golgi transport

scientific journal article

An intermittent live cell imaging screen for siRNA enhancers and suppressors of a kinesin-5 inhibitor

artículo científico publicado en 2009

Analysis of mitosis and antimitotic drug responses in tumors by in vivo microscopy and single-cell pharmacodynamics.

artículo científico publicado en 2011

Caveolin-1 interacts directly with dynamin-2.

artículo científico publicado en 2005

Cell death when the SAC is out of commission

scientific article published on 01 June 2010

Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5.

artículo científico publicado en 2008

Cortactin is a component of clathrin-coated pits and participates in receptor-mediated endocytosis

scientific journal article

Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly.

artículo científico publicado en 2009

Get off my back! Rapid receptor internalization through circular dorsal ruffles.

artículo científico publicado en 2006

In vivo cell-cycle profiling in xenograft tumors by quantitative intravital microscopy

artículo científico publicado en 2015

Inhibition of exportin-1 function results in rapid cell cycle-associated DNA damage in cancer cells.

artículo científico publicado en 2017

Longitudinal tracking of single live cancer cells to understand cell cycle effects of the nuclear export inhibitor, selinexor.

artículo científico publicado en 2015

Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction

artículo científico publicado en 2011

Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate

artículo científico publicado en 2008

Rapid induction of apoptosis during Kinesin-5 inhibitor-induced mitotic arrest in HL60 cells.

artículo científico publicado en 2011

Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin.

artículo científico publicado en 2014

Testis-specific murine centrin, Cetn1: genomic characterization and evidence for retroposition of a gene encoding a centrosome protein.

artículo científico publicado en 1999

Through the Looking Glass: Time-lapse Microscopy and Longitudinal Tracking of Single Cells to Study Anti-cancer Therapeutics.

artículo científico publicado en 2016