Lista de obras - Alastair Stewart - Dominio Público Uruguay

1-O-hexadecyl-2-acetyl-sn-glycero-3-phospho (N,N,N trimethyl) hexanolamine: an analogue of platelet-activating factor with partial agonist activity.

artículo científico publicado en 1991

2-Morpholinoisoflav-3-enes as flexible intermediates in the synthesis of phenoxodiol, isophenoxodiol, equol and analogues: vasorelaxant properties, estrogen receptor binding and Rho/RhoA kinase pathway inhibition.

artículo científico publicado en 2012

2-methoxyestradiol is an estrogen receptor agonist that supports tumor growth in murine xenograft models of breast cancer.

artículo científico publicado en 2005

A model of bridging angiogenesis in the rat.

artículo científico publicado en 1998

A randomized phase II trial of granulocyte-macrophage colony-stimulating factor therapy in severe sepsis with respiratory dysfunction.

artículo científico publicado en 2002

Airway remodelling in asthma: current understanding and implications for future therapies.

artículo científico publicado en 2006

Airway smooth muscle remodels pericellular collagen fibrils: implications for proliferation

scientific article published on 15 January 2010

Airway vascularity in asthma

artículo científico publicado en 1999

Airway wall remodelling and hyperresponsiveness: modelling remodelling in vitro and in vivo.

artículo científico publicado en 2001

Airways smooth muscle: the next generation

artículo científico publicado en 2009

Albumin inhibits platelet-activating factor (PAF)-induced responses in platelets and macrophages: implications for the biologically active form of PAF ⬇️

artículo científico publicado el 1 de septiembre de 1992

Altered activation of the L-arginine nitric oxide pathway during and after cardiopulmonary bypass.

artículo científico publicado en 1997

Annexin A1 influences in breast cancer: Controversies on contributions to tumour, host and immunoediting processes

artículo científico publicado en 2017

Annexin A2 contributes to lung injury and fibrosis by augmenting factor Xa fibrogenic activity.

artículo científico publicado en 2017

Antagonism of vasoconstriction induced by platelet-activating factor in guinea-pig perfused hearts by selective platelet-activating factor receptor antagonists

artículo científico publicado en 1987

Anti-remodelling drugs for the treatment of asthma: requirement for animal models of airway wall remodelling.

artículo científico publicado en 2001

Antigen-induced airway inflammation in the Brown Norway rat results in airway smooth muscle hyperplasia.

artículo científico publicado en 2002

Attenuation of antigen-induced bronchospasm by fenoterol in the guinea-pig ⬇️

artículo científico publicado el 1 de enero de 1984

Beta 2-adrenoceptor agonist-mediated inhibition of human airway smooth muscle cell proliferation: importance of the duration of beta 2-adrenoceptor stimulation.

artículo científico publicado en 1997

Beta2-adrenergic receptor agonists and cAMP arrest human cultured airway smooth muscle cells in the G(1) phase of the cell cycle: role of proteasome degradation of cyclin D1

artículo científico publicado en 1999

Biased signalling from the glucocorticoid receptor: Renewed opportunity for tailoring glucocorticoid activity.

artículo científico publicado en 2016

Bronchial epithelial cells are rendered insensitive to glucocorticoid transactivation by transforming growth factor-β1.

artículo científico publicado en 2014

CD151, a laminin receptor showing increased expression in asthmatic patients, contributes to airway hyperresponsiveness through calcium signaling.

artículo científico publicado en 2016

Can we differentiate between airway and vascular smooth muscle?

artículo científico publicado en 2004

Cardioprotective potential of annexin-A1 mimetics in myocardial infarction

artículo científico publicado en 2014

Casein Kinase 1δ/ε Inhibitor, PF670462 Attenuates the Fibrogenic Effects of Transforming Growth Factor-β in Pulmonary Fibrosis

artículo científico publicado en 2018

Cellular Biomechanics in Drug Screening and Evaluation: Mechanopharmacology

artículo científico publicado en 2016

Coal mine dust lung disease in the modern era.

artículo científico publicado en 2017

Collagen impairs glucocorticoid actions in airway smooth muscle through integrin signalling.

artículo científico publicado en 2006

Continuous plasmafiltration in sepsis syndrome. Plasmafiltration in Sepsis Study Group

scientific article published on 01 October 1999

Contribution of the p38MAPK signalling pathway to proliferation in human cultured airway smooth muscle cells is mitogen-specific.

artículo científico publicado en 2004

Cool perfusion solutions for skin flaps: a new mixture of pharmacological agents which improves skin flap viability

artículo científico publicado en 1995

Cortisol limits selected actions of synthetic glucocorticoids in the airway epithelium

artículo científico publicado en 2017

Differential inhibition of thrombin- and EGF-stimulated human cultured airway smooth muscle proliferation by glucocorticoids.

artículo científico publicado en 2003

Do inflammatory mediators influence the contribution of airway smooth muscle contraction to airway hyperresponsiveness in asthma?

artículo científico publicado en 2003

Dual modes of action for disodium cromoglycate in inhibition of antigen-induced contractions of guinea-pig isolated airways smooth muscle.

artículo científico publicado en 1983

Effects of low dose intra-arterial monoclonal antibodies to ICAM-1 and CD11/CD18 on local and systemic consequences of ischaemia-reperfusion injury in skeletal muscle

artículo científico publicado en 1996

Evidence for an intracellular action of platelet-activating factor in bovine cultured aortic endothelial cells

artículo científico publicado en 1989

Extracellular matrix, integrins, and mesenchymal cell function in the airways.

artículo científico publicado en 2006

Factors controlling airway smooth muscle proliferation in asthma.

artículo científico publicado en 2004

Functional and genomic characterization of a xenograft model system for the study of metastasis in triple-negative breast cancer.

artículo científico publicado en 2018

Functional expression of IgG-Fc receptors in human airway smooth muscle cells.

artículo científico publicado en 2010

Glucocorticoid Insensitivity in Virally Infected Airway Epithelial Cells Is Dependent on Transforming Growth Factor-β Activity.

artículo científico publicado en 2017

Glucocorticoid resistance of migration and gene expression in a daughter MDA-MB-231 breast tumour cell line selected for high metastatic potential

artículo científico publicado en 2017

Glucocorticoid-resistant asthma and novel anti-inflammatory drugs.

artículo científico publicado en 2012

Glucocorticoids inhibit proliferation, cyclin D1 expression, and retinoblastoma protein phosphorylation, but not activity of the extracellular-regulated kinases in human cultured airway smooth muscle

scientific article published on 01 July 1999

Heterogeneity in mechanisms influencing glucocorticoid sensitivity: the need for a systems biology approach to treatment of glucocorticoid-resistant inflammation.

artículo científico publicado en 2015

Human monocytes maintained in culture acquire functional responsiveness to platelet-activating factor that is independent of increases in protein tyrosine phosphorylation

artículo científico publicado en 1997

Impact of extracellular matrix and strain on proliferation of bovine airway smooth muscle.

artículo científico publicado en 2003

Inducible nitric oxide synthase (iNOS) activity promotes ischaemic skin flap survival

artículo científico publicado en 2001

Inflammation: maladies, models, mechanisms and molecules

artículo científico publicado en 2016

Inhibition by salbutamol of the proliferation of human airway smooth muscle cells grown in culture

artículo científico publicado en 1994

Interaction of leukotriene D4 and histamine on bronchomotor tone, in the guinea-pig.

artículo científico publicado en 1983

Interleukin-1alpha and tumour necrosis factor-alpha modulate airway smooth muscle DNA synthesis by induction of cyclo-oxygenase-2: inhibition by dexamethasone and fluticasone propionate

artículo científico publicado en 1999

Involvement of capsaicin-sensitive afferent neurones in a vagal-dependent interaction between leukotriene D4 and histamine on bronchomotor tone ⬇️

artículo científico publicado el 1 de diciembre de 1984

Ischaemia-reperfusion injury in mouse skeletal muscle is reduced by N omega-nitro-L-arginine methyl ester and dexamethasone

artículo científico publicado en 1997

Leukotriene D4 potentiates histamine-induced bronchoconstriction in guinea-pigs.

artículo científico publicado en 1984

Lipopolysaccharide-induced cell cycle arrest in macrophages occurs independently of nitric oxide synthase II induction.

artículo científico publicado en 2001

Localization of inducible nitric oxide synthase to mast cells during ischemia/reperfusion injury of skeletal muscle

artículo científico publicado en 2000

Macrophage activation reduces mobilization of arachidonic acid by guinea-pig and rat peritoneal macrophages in vitro

artículo científico publicado en 1990

Mitogenic actions of endothelin-1 and epidermal growth factor in cultured airway smooth muscle.

artículo científico publicado en 1994

Molecular and cellular targets in tissue remodelling

artículo científico publicado en 2006

More muscle in asthma, but where did it come from?

scientific article published on 01 May 2012

Neonatal pneumococcal colonisation caused by Influenza A infection alters lung function in adult mice

artículo científico publicado en 2016

Neutrophil-independent protective effect of r-metHuG-CSF in ischaemia-reperfusion injury in rat skeletal muscle

artículo científico publicado en 2000

Nitric oxide synthase inhibitor, nitro-iminoethyl-L-ornithine, reduces ischemia-reperfusion injury in rabbit skeletal muscle

artículo científico publicado en 1994

Nitric oxide synthase inhibitors improve skin flap survival in the rat

artículo científico publicado en 1994

Nitric oxide synthase-independent generation of nitric oxide in rat skeletal muscle ischemia-reperfusion injury

artículo científico publicado en 1999

Nitrite is produced by elicited but not by circulating neutrophils.

artículo científico publicado en 1993

Non-steroidal anti-inflammatory drugs, tumour immunity and immunotherapy ⬇️

artículo científico publicado el 21 de febrero de 2012

On the terminology for describing the length-force relationship and its changes in airway smooth muscle

artículo científico publicado en 2004

On-chip surface acoustic wave and micropipette aspiration techniques to assess cell elastic properties

artículo científico publicado en 2020

PPAR gamma ligands, 15-deoxy-delta12,14-prostaglandin J2 and rosiglitazone regulate human cultured airway smooth muscle proliferation through different mechanisms

artículo científico publicado en 2004

Plasminogen activation by airway smooth muscle is regulated by type I collagen

artículo científico publicado en 2010

Plasminogen-stimulated airway smooth muscle cell proliferation is mediated by urokinase and annexin A2, involving plasmin-activated cell signalling.

artículo científico publicado en 2013

Plasminogen-stimulated inflammatory cytokine production by airway smooth muscle cells is regulated by annexin A2.

artículo científico publicado en 2013

Platelet serotonin release in rheumatoid arthritis: a study in food-intolerant patients

scientific article published on 01 August 1983

Platelet-activating factor and WEB-2086 directly modulate rat cardiomyocyte contractility

artículo científico publicado en 1994

Platelet-activating factor biosynthesis in rat vascular smooth muscle cells

scientific article published on 01 May 1994

Platelet-activating factor may participate in signal transduction processes in rabbit leukocytes.

artículo científico publicado en 1991

Platelet-activating factor-induced vasoconstriction in rat isolated, perfused hearts: contribution of cyclo-oxygenase and lipoxygenase arachidonic acid metabolites

artículo científico publicado en 1986

Potential for airway smooth muscle as therapeutic target is reflected in the breadth of expertise of next generation scientists

artículo científico publicado en 2012

Prior heat stress improves survival of ischemic-reperfused skeletal muscle in vivo

artículo científico publicado en 2000

Pro-inflammatory mediators increase levels of the noncoding RNA GAS5 in airway smooth muscle and epithelial cells

artículo científico publicado en 2014

Proliferative aspects of airway smooth muscle.

artículo científico publicado en 2004

Pulmonary therapeutics: rethinking the regimens and re-imagining the targets.

artículo científico publicado en 2013

Quantitative phase microscopy: a new tool for measurement of cell culture growth and confluency in situ.

artículo científico publicado en 2004

R2D(2) for C(4)Eo: an 'alliance' of PGD(2) receptors is required for LTC(4) production by human eosinophils

artículo científico publicado en 2011

Refractive index measurement in viable cells using quantitative phase-amplitude microscopy and confocal microscopy

artículo científico publicado en 2005

Regulation of human airway mesenchymal cell proliferation by glucocorticoids and beta2-adrenoceptor agonists.

artículo científico publicado en 2005

Regulation of lung fibroblast activation by annexin A1.

artículo científico publicado en 2013

Resistance of fibrogenic responses to glucocorticoid and 2-methoxyestradiol in bleomycin-induced lung fibrosis in miceThis article is one of a selection of papers published in the Special Issue on Recent Advances in Asthma Research

artículo científico publicado en 2007

Resolvin D2 supports MCF-7 cell proliferation via activation of estrogen receptor

artículo científico publicado en 2014

Safer approaches to therapeutic modulation of TGF-β signaling for respiratory disease

artículo científico publicado en 2018

Salbutamol inhibits the proliferation of human airway smooth muscle cells grown in culture: relationship to elevated cAMP levels

scientific article published on 01 June 1995

Secreted factors from human mast cells trigger inflammatory cytokine production by human airway smooth muscle cells.

artículo científico publicado en 2012

Small-molecule-biased formyl peptide receptor agonist compound 17b protects against myocardial ischaemia-reperfusion injury in mice.

scientific article published on 07 February 2017

TGF-β: Master regulator of inflammation and fibrosis

artículo científico publicado en 2018

Targeted Graphene Oxide Networks: Cytotoxicity and Synergy with Anticancer Agents

scientific article published on 07 December 2018

The Coagulant Factor Xa Induces Protease-Activated Receptor-1 and Annexin A2-Dependent Airway Smooth Muscle Cytokine Production and Cell Proliferation.

artículo científico publicado en 2015

The antimalarial drug artesunate inhibits primary human cultured airway smooth muscle cell proliferation.

artículo científico publicado en 2014

The effect of glucocorticoids on proliferation of human cultured airway smooth muscle.

artículo científico publicado en 1995

The fibrogenic actions of lung fibroblast-derived urokinase: a potential drug target in IPF.

scientific article published on 31 January 2017

The influence of nitric oxide synthase 2 on cutaneous wound angiogenesis

artículo científico publicado en 2011

The role of cellular adhesion molecules in surgery.

artículo científico publicado en 1995

The role of potassium channels in the inhibitory effects of beta 2-adrenoceptor agonists on DNA synthesis in human cultured airway smooth muscle.

artículo científico publicado en 1997

The survival of skeletal muscle myoblasts in vitro is sensitive to a donor of nitric oxide and superoxide, SIN-1, but not to nitric oxide or peroxynitrite alone.

artículo científico publicado en 1999

Thrombin-stimulated DNA synthesis in human cultured airway smooth muscle occurs independently of products of cyclo-oxygenase or 5-lipoxygenase.

artículo científico publicado en 2000

Timing of Administration of Dexamethasone or the Nitric Oxide Synthase Inhibitor, Nitro-l-Arginine Methyl Ester, is Critical for Effective Treatment of Ischaemia-Reperfusion Injury to Rat Skeletal Muscle ⬇️

artículo científico publicado el 1 de agosto de 1997

Total synthesis of the endogenous inflammation resolving lipid resolvin D2 using a common lynchpin.

artículo científico publicado en 2013

Transforming Growth Factor–β–Induced Differentiation of Airway Smooth Muscle Cells Is Inhibited by Fibroblast Growth Factor–2 ⬇️

artículo científico publicado el 13 de diciembre de 2012

Transforming growth factor-β impairs glucocorticoid activity in the A549 lung adenocarcinoma cell line.

artículo científico publicado en 2012

Translational Pharmacology

artículo científico publicado en 2017

Tumor necrosis factor alpha modulates mitogenic responses of human cultured airway smooth muscle

article by Alastair Stewart et al published 1 January 1995 in American Journal of Respiratory Cell and Molecular Biology

Lista de obras de Alastair Stewart

1-O-hexadecyl-2-acetyl-sn-glycero-3-phospho (N,N,N trimethyl) hexanolamine: an analogue of platelet-activating factor with partial agonist activity.

2-Morpholinoisoflav-3-enes as flexible intermediates in the synthesis of phenoxodiol, isophenoxodiol, equol and analogues: vasorelaxant properties, estrogen receptor binding and Rho/RhoA kinase pathway inhibition.

2-methoxyestradiol is an estrogen receptor agonist that supports tumor growth in murine xenograft models of breast cancer.

A model of bridging angiogenesis in the rat.

A randomized phase II trial of granulocyte-macrophage colony-stimulating factor therapy in severe sepsis with respiratory dysfunction.

Airway remodelling in asthma: current understanding and implications for future therapies.

Airway smooth muscle remodels pericellular collagen fibrils: implications for proliferation

Airway vascularity in asthma

Airway wall remodelling and hyperresponsiveness: modelling remodelling in vitro and in vivo.

Airways smooth muscle: the next generation

Albumin inhibits platelet-activating factor (PAF)-induced responses in platelets and macrophages: implications for the biologically active form of PAF ⬇️

Altered activation of the L-arginine nitric oxide pathway during and after cardiopulmonary bypass.

Annexin A1 influences in breast cancer: Controversies on contributions to tumour, host and immunoediting processes

Annexin A2 contributes to lung injury and fibrosis by augmenting factor Xa fibrogenic activity.

Antagonism of vasoconstriction induced by platelet-activating factor in guinea-pig perfused hearts by selective platelet-activating factor receptor antagonists

Anti-remodelling drugs for the treatment of asthma: requirement for animal models of airway wall remodelling.

Antigen-induced airway inflammation in the Brown Norway rat results in airway smooth muscle hyperplasia.

Attenuation of antigen-induced bronchospasm by fenoterol in the guinea-pig ⬇️

Beta 2-adrenoceptor agonist-mediated inhibition of human airway smooth muscle cell proliferation: importance of the duration of beta 2-adrenoceptor stimulation.

Beta2-adrenergic receptor agonists and cAMP arrest human cultured airway smooth muscle cells in the G(1) phase of the cell cycle: role of proteasome degradation of cyclin D1

Biased signalling from the glucocorticoid receptor: Renewed opportunity for tailoring glucocorticoid activity.

Bronchial epithelial cells are rendered insensitive to glucocorticoid transactivation by transforming growth factor-β1.

CD151, a laminin receptor showing increased expression in asthmatic patients, contributes to airway hyperresponsiveness through calcium signaling.

Can we differentiate between airway and vascular smooth muscle?

Cardioprotective potential of annexin-A1 mimetics in myocardial infarction

Casein Kinase 1δ/ε Inhibitor, PF670462 Attenuates the Fibrogenic Effects of Transforming Growth Factor-β in Pulmonary Fibrosis

Cellular Biomechanics in Drug Screening and Evaluation: Mechanopharmacology

Coal mine dust lung disease in the modern era.

Collagen impairs glucocorticoid actions in airway smooth muscle through integrin signalling.

Continuous plasmafiltration in sepsis syndrome. Plasmafiltration in Sepsis Study Group

Contribution of the p38MAPK signalling pathway to proliferation in human cultured airway smooth muscle cells is mitogen-specific.

Cool perfusion solutions for skin flaps: a new mixture of pharmacological agents which improves skin flap viability

Cortisol limits selected actions of synthetic glucocorticoids in the airway epithelium

Differential inhibition of thrombin- and EGF-stimulated human cultured airway smooth muscle proliferation by glucocorticoids.

Do inflammatory mediators influence the contribution of airway smooth muscle contraction to airway hyperresponsiveness in asthma?

Dual modes of action for disodium cromoglycate in inhibition of antigen-induced contractions of guinea-pig isolated airways smooth muscle.

Effects of low dose intra-arterial monoclonal antibodies to ICAM-1 and CD11/CD18 on local and systemic consequences of ischaemia-reperfusion injury in skeletal muscle

Evidence for an intracellular action of platelet-activating factor in bovine cultured aortic endothelial cells

Extracellular matrix, integrins, and mesenchymal cell function in the airways.

Factors controlling airway smooth muscle proliferation in asthma.

Functional and genomic characterization of a xenograft model system for the study of metastasis in triple-negative breast cancer.

Functional expression of IgG-Fc receptors in human airway smooth muscle cells.

Glucocorticoid Insensitivity in Virally Infected Airway Epithelial Cells Is Dependent on Transforming Growth Factor-β Activity.

Glucocorticoid resistance of migration and gene expression in a daughter MDA-MB-231 breast tumour cell line selected for high metastatic potential

Glucocorticoid-resistant asthma and novel anti-inflammatory drugs.

Glucocorticoids inhibit proliferation, cyclin D1 expression, and retinoblastoma protein phosphorylation, but not activity of the extracellular-regulated kinases in human cultured airway smooth muscle

Heterogeneity in mechanisms influencing glucocorticoid sensitivity: the need for a systems biology approach to treatment of glucocorticoid-resistant inflammation.

Human monocytes maintained in culture acquire functional responsiveness to platelet-activating factor that is independent of increases in protein tyrosine phosphorylation

Impact of extracellular matrix and strain on proliferation of bovine airway smooth muscle.

Inducible nitric oxide synthase (iNOS) activity promotes ischaemic skin flap survival

Inflammation: maladies, models, mechanisms and molecules

Inhibition by salbutamol of the proliferation of human airway smooth muscle cells grown in culture

Interaction of leukotriene D4 and histamine on bronchomotor tone, in the guinea-pig.

Interleukin-1alpha and tumour necrosis factor-alpha modulate airway smooth muscle DNA synthesis by induction of cyclo-oxygenase-2: inhibition by dexamethasone and fluticasone propionate

Involvement of capsaicin-sensitive afferent neurones in a vagal-dependent interaction between leukotriene D4 and histamine on bronchomotor tone ⬇️

Ischaemia-reperfusion injury in mouse skeletal muscle is reduced by N omega-nitro-L-arginine methyl ester and dexamethasone

Leukotriene D4 potentiates histamine-induced bronchoconstriction in guinea-pigs.

Lipopolysaccharide-induced cell cycle arrest in macrophages occurs independently of nitric oxide synthase II induction.

Localization of inducible nitric oxide synthase to mast cells during ischemia/reperfusion injury of skeletal muscle

Macrophage activation reduces mobilization of arachidonic acid by guinea-pig and rat peritoneal macrophages in vitro

Mitogenic actions of endothelin-1 and epidermal growth factor in cultured airway smooth muscle.

Molecular and cellular targets in tissue remodelling

More muscle in asthma, but where did it come from?

Neonatal pneumococcal colonisation caused by Influenza A infection alters lung function in adult mice

Neutrophil-independent protective effect of r-metHuG-CSF in ischaemia-reperfusion injury in rat skeletal muscle

Nitric oxide synthase inhibitor, nitro-iminoethyl-L-ornithine, reduces ischemia-reperfusion injury in rabbit skeletal muscle

Nitric oxide synthase inhibitors improve skin flap survival in the rat

Nitric oxide synthase-independent generation of nitric oxide in rat skeletal muscle ischemia-reperfusion injury

Nitrite is produced by elicited but not by circulating neutrophils.

Non-steroidal anti-inflammatory drugs, tumour immunity and immunotherapy ⬇️

On the terminology for describing the length-force relationship and its changes in airway smooth muscle

On-chip surface acoustic wave and micropipette aspiration techniques to assess cell elastic properties

PPAR gamma ligands, 15-deoxy-delta12,14-prostaglandin J2 and rosiglitazone regulate human cultured airway smooth muscle proliferation through different mechanisms

Plasminogen activation by airway smooth muscle is regulated by type I collagen

Plasminogen-stimulated airway smooth muscle cell proliferation is mediated by urokinase and annexin A2, involving plasmin-activated cell signalling.

Plasminogen-stimulated inflammatory cytokine production by airway smooth muscle cells is regulated by annexin A2.

Platelet serotonin release in rheumatoid arthritis: a study in food-intolerant patients

Platelet-activating factor and WEB-2086 directly modulate rat cardiomyocyte contractility

Platelet-activating factor biosynthesis in rat vascular smooth muscle cells