Lista de obras - Esther M Bulloch - Dominio Público Uruguay

A covalent adduct of MbtN, an acyl-ACP dehydrogenase from Mycobacterium tuberculosis, reveals an unusual acyl-binding pocket

artículo científico publicado en 2015

Allosteric regulation of menaquinone (vitamin K2) biosynthesis in the human pathogen Mycobacterium tuberculosis

artículo científico publicado en 2020

Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis

artículo científico publicado en 2014

Corrigendum: Repurposing the Chemical Scaffold of the Anti-Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis inMycobacterium tuberculosis

artículo científico publicado en 2015

Design and synthesis of aromatic inhibitors of anthranilate synthase

artículo científico publicado en 2005

Design and synthesis of aromatic inhibitors of anthranilate synthase

artículo científico publicado en 2005

Detection of covalent intermediates formed in the reaction of 4-amino-4-deoxychorismate synthase.

artículo científico publicado en 2005

Hydrolysis of the 5'-p-nitrophenyl ester of TMP by the proofreading exonuclease (epsilon) subunit of Escherichia coli DNA polymerase III.

artículo científico publicado en 2002

Identification of 4-amino-4-deoxychorismate synthase as the molecular target for the antimicrobial action of (6s)-6-fluoroshikimate

artículo científico publicado en 2004

Identifying protein domains by global analysis of soluble fragment data

artículo científico publicado en 2014

Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis

artículo científico publicado en 2012

Inhibition of chorismate-utilising enzymes by 2-amino-4-carboxypyridine and 4-carboxypyridone and 5-carboxypyridone analogues

artículo científico publicado en 2010

Inhibition studies of Mycobacterium tuberculosis salicylate synthase (MbtI)

artículo científico publicado en 2010

NMR chemical shift assignment of the C-terminal region of the Menangle virus phosphoprotein

scientific article published on 24 January 2019

Protein domain definition should allow for conditional disorder

artículo científico publicado en 2013

Purification, crystallization and preliminary X-ray studies of MbtN (Rv1346) from Mycobacterium tuberculosis

artículo científico publicado en 2013

Removal of the C-terminal regulatory domain of α-isopropylmalate synthase disrupts functional substrate binding

artículo científico publicado en 2012

Repurposing the chemical scaffold of the anti-arthritic drug Lobenzarit to target tryptophan biosynthesis in Mycobacterium tuberculosis

artículo científico publicado en 2014

Structural Analyses of a Purine Biosynthetic Enzyme from Mycobacterium tuberculosis Reveal a Novel Bound Nucleotide

artículo científico publicado en 2011

Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms

artículo científico publicado en 2016

Structure and function of GlmU fromMycobacterium tuberculosis

artículo científico publicado en 2009

Structure and function of human xylulokinase, an enzyme with important roles in carbohydrate metabolism

artículo científico publicado en 2013

Structure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complex

artículo científico publicado en 2015

Synthesis and evaluation of 2,5-dihydrochorismate analogues as inhibitors of the chorismate-utilising enzymes

artículo científico publicado en 2009

Synthesis and evaluation of M. tuberculosis salicylate synthase (MbtI) inhibitors designed to probe plasticity in the active site.

artículo científico publicado en 2012

The TB Structural Genomics Consortium: a decade of progress

artículo científico publicado en 2011

The substrate capture mechanism of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase provides a mode for inhibition

artículo científico publicado en 2013

Transient dimerization of human MxA promotes GTP hydrolysis, resulting in a mechanical power stroke

artículo científico publicado en 2014

Lista de obras de Esther M Bulloch

A covalent adduct of MbtN, an acyl-ACP dehydrogenase from Mycobacterium tuberculosis, reveals an unusual acyl-binding pocket

Allosteric regulation of menaquinone (vitamin K2) biosynthesis in the human pathogen Mycobacterium tuberculosis

Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis

Corrigendum: Repurposing the Chemical Scaffold of the Anti-Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis inMycobacterium tuberculosis

Design and synthesis of aromatic inhibitors of anthranilate synthase

Design and synthesis of aromatic inhibitors of anthranilate synthase

Detection of covalent intermediates formed in the reaction of 4-amino-4-deoxychorismate synthase.

Hydrolysis of the 5'-p-nitrophenyl ester of TMP by the proofreading exonuclease (epsilon) subunit of Escherichia coli DNA polymerase III.

Identification of 4-amino-4-deoxychorismate synthase as the molecular target for the antimicrobial action of (6s)-6-fluoroshikimate

Identifying protein domains by global analysis of soluble fragment data

Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis

Inhibition of chorismate-utilising enzymes by 2-amino-4-carboxypyridine and 4-carboxypyridone and 5-carboxypyridone analogues

Inhibition studies of Mycobacterium tuberculosis salicylate synthase (MbtI)

NMR chemical shift assignment of the C-terminal region of the Menangle virus phosphoprotein

Protein domain definition should allow for conditional disorder

Purification, crystallization and preliminary X-ray studies of MbtN (Rv1346) from Mycobacterium tuberculosis

Removal of the C-terminal regulatory domain of α-isopropylmalate synthase disrupts functional substrate binding

Repurposing the chemical scaffold of the anti-arthritic drug Lobenzarit to target tryptophan biosynthesis in Mycobacterium tuberculosis

Structural Analyses of a Purine Biosynthetic Enzyme from Mycobacterium tuberculosis Reveal a Novel Bound Nucleotide

Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms

Structure and function of GlmU fromMycobacterium tuberculosis

Structure and function of human xylulokinase, an enzyme with important roles in carbohydrate metabolism

Structure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complex

Synthesis and evaluation of 2,5-dihydrochorismate analogues as inhibitors of the chorismate-utilising enzymes

Synthesis and evaluation of M. tuberculosis salicylate synthase (MbtI) inhibitors designed to probe plasticity in the active site.

The TB Structural Genomics Consortium: a decade of progress

The substrate capture mechanism of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase provides a mode for inhibition

Transient dimerization of human MxA promotes GTP hydrolysis, resulting in a mechanical power stroke