Filtros de búsqueda

Lista de obras de David Capper

2-Hydroxyglutarate concentration in serum from patients with gliomas does not correlate with IDH1/2 mutation status or tumor size

artículo científico publicado en 2011

A 49-year old female with multiple extra-axial tumors

artículo científico publicado en 2017

A Phase II randomized study of galunisertib monotherapy or galunisertib plus lomustine compared with lomustine monotherapy in patients with recurrent glioblastoma

artículo científico publicado en 2016

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

artículo científico publicado en 2013

A single-arm phase II Austrian/German multicenter trial on continuous daily sunitinib in primary glioblastoma at first recurrence (SURGE 01-07).

artículo científico publicado en 2013

ACTH- and prolactin-producing pituitary gland microadenoma with biphasic features of atypia and intermediate filament expression

artículo científico publicado en 2006

ACTR-05. THE RANDOMIZED PHASE II ARTE TRIAL: BEVACIZUMAB PLUS HYPOFRACTIONATED RADIOTHERAPY VERSUS RADIOTHERAPY ALONE IN ELDERLY PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA.

artículo científico publicado en 2017

AKT1E17K mutations cluster with meningothelial and transitional meningiomas and can be detected by SFRP1 immunohistochemistry

artículo científico publicado en 2013

AT-10ATYPICAL TERATOID RHABDOID TUMORS AND POORLY DIFFERENTIATED CHORDOMAS: DISTINCT MOLECULAR ENTITIES WITH SMARCB1/INI1 LOSS AND DISMAL PROGNOSIS.

artículo científico publicado en 2016

AT-11CRIBRIFORM NEUROEPITHELIAL TUMOR (CRINET): MOLECULAR CHARACTERIZATION OF A SMARCB1-DEFICIENT NON-RHABDOID TUMOR WITH FAVORABLE LONG-TERM OUTCOME.

artículo científico publicado en 2016

ATNT-07FAVORABLE RESPONSE OF PATIENTS WITH GLIOBLASTOMA AT SECOND OR THIRD RECURRENCE TO REPEATED INJECTION OF ONCOLYTIC PARVOVIRUS H-1 IN COMBINATION WITH BEVACICUMAB.

artículo científico publicado en 2015

ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma

artículo científico publicado en 2014

ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis

artículo científico publicado en 2013

Abstract 3094: Epigenetic classification of ependymal brain tumors across age groups

Abstract LB-172: Novel candidate oncogenic drivers in pineoblastoma

Accurate calling of KIAA1549-BRAF fusions from DNA of human brain tumours using methylation array-based copy number and gene panel sequencing data

artículo científico publicado en 2020

Actively personalized vaccination trial for newly diagnosed glioblastoma

scientific article published on 19 December 2018

Adamantinomatous and papillary craniopharyngiomas are characterized by distinct epigenomic as well as mutational and transcriptomic profiles

artículo científico publicado en 2016

Addressing diffuse glioma as a systemic brain disease with single-cell analysis

artículo científico publicado en 2011

Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities

artículo científico publicado en 2015

Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma

artículo científico publicado en 2011

Analysis of IDH mutation, 1p/19q deletion, and PTEN loss delineates prognosis in clinical low-grade diffuse gliomas

artículo científico publicado en 2014

Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations

artículo científico publicado en 2018

Announcing cIMPACT-NOW: the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy

artículo científico publicado en 2016

Anti-tissue factor (TF9-10H10) treatment reduces tumor cell invasiveness in a novel migratory glioma model

artículo científico publicado en 2013

Application of mutant IDH1 antibody to differentiate diffuse glioma from nonneoplastic central nervous system lesions and therapy-induced changes

artículo científico publicado en 2010

Assessing CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide data in the biomarker cohort of the NOA-04 trial

artículo científico publicado en 2014

Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody

artículo científico publicado en 2011

Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes

artículo científico publicado en 2016

BRAF Fusion Analysis in Pilocytic Astrocytomas: KIAA1549-BRAF 15-9 Fusions Are More Frequent in the Midline Than Within the Cerebellum

artículo científico publicado en 2015

BRAF V600E analysis for the differentiation of papillary craniopharyngiomas and Rathke's cleft cysts.

artículo científico publicado en 2015

BRAF V600E mutation is associated with mTOR signaling activation in glioneuronal tumors

artículo científico publicado en 2013

BRAF V600E-specific immunohistochemistry reveals low mutation rates in biliary tract cancer and restriction to intrahepatic cholangiocarcinoma

artículo científico publicado en 2013

BRAF-mutated pleomorphic xanthoastrocytoma is associated with temporal location, reticulin fiber deposition and CD34 expression

artículo científico publicado en 2014

BRAFV600E immunohistochemistry facilitates universal screening of colorectal cancers for Lynch syndrome

artículo científico publicado en 2013

BRAFV600E mutant protein is expressed in cells of variable maturation in Langerhans cell histiocytosis.

artículo científico publicado en 2012

Bevacizumab plus hypofractionated radiotherapy versus radiotherapy alone in elderly patients with glioblastoma: the randomized, open-label, phase II ARTE trial

artículo científico publicado en 2018

Biomarker and Histopathology Evaluation of Patients with Recurrent Glioblastoma Treated with Galunisertib, Lomustine, or the Combination of Galunisertib and Lomustine

artículo científico publicado en 2017

Brain metastases of gastro-oesophageal cancer: evaluation of molecules with relevance for targeted therapies

artículo científico publicado en 2013

CASP9 germline mutation in a family with multiple brain tumors

artículo científico publicado en 2016

Challenges in the histopathological classification of ganglioglioma and DNT: microscopic agreement studies and a preliminary genotype-phenotype analysis

scientific article published on 09 December 2018

Characterization of R132H mutation-specific IDH1 antibody binding in brain tumors

artículo científico publicado en 2009

Chemotherapy with BCNU in recurrent glioma: Analysis of clinical outcome and side effects in chemotherapy-naïve patients

artículo científico publicado en 2015

Chromogenic in situ hybridization is a reliable alternative to fluorescence in situ hybridization for diagnostic testing of 1p and 19q loss in paraffin-embedded gliomas

artículo científico publicado en 2012

Classification of gliomas. Current progress and perspectives

artículo científico publicado en 2015

Clinical neuropathology practice news 2-2012: BRAF V600E testing

artículo científico publicado en 2012

Coincidence of semilobar holoprosencephaly and Chiari II malformation: correlation of prenatal diagnostics and neuropathologic findings

artículo científico publicado en 2006

Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astrocytoma.

artículo científico publicado en 2009

Comparative integrated molecular analysis of intraocular medulloepitheliomas and central nervous system embryonal tumors with multilayered rosettes confirms that they are distinct nosologic entities

artículo científico publicado en 2015

Confirmation of R132H mutation of isocitrate dehydrogenase 1 as an independent prognostic factor in anaplastic astrocytoma

artículo científico publicado en 2011

Continued response off treatment after BRAF inhibition in refractory hairy cell leukemia

artículo científico publicado en 2013

Correction to: DNA methylation-based reclassification of olfactory neuroblastoma

artículo científico publicado en 2018

Cribriform neuroepithelial tumor: molecular characterization of a SMARCB1-deficient non-rhabdoid tumor with favorable long-term outcome

artículo científico publicado en 2016

Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion–Positive Supratentorial Ependymomas

artículo científico publicado en 2021

DNA methylation profiling identifies two distinct subgroups in breast cancers with low hormone receptor expression, mainly associated with HER2 amplification status

artículo científico publicado en 2021

DNA methylation profiling reliably distinguishes pulmonary enteric adenocarcinoma from metastatic colorectal cancer

artículo científico publicado en 2019

DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis

artículo científico publicado en 2017

DNA methylation-based classification of central nervous system tumours

artículo científico publicado en 2018

DNA methylation-based classification of ependymomas in adulthood: implications for diagnosis and treatment

artículo científico publicado en 2018

DNA methylation-based reclassification of olfactory neuroblastoma

artículo científico publicado en 2018

Defective p53 antiangiogenic signaling in glioblastoma

artículo científico publicado en 2010

Desmoplastic Infantile Ganglioglioma/Astrocytoma (DIG/DIA) Are Distinct Entities with Frequent BRAFV600 Mutations

article

Detection of 2-hydroxyglutarate in formalin-fixed paraffin-embedded glioma specimens by gas chromatography/mass spectrometry

artículo científico

Detection of BRAF p.V600E Mutations in Melanoma by Immunohistochemistry Has a Good Interobserver Reproducibility

artículo científico publicado en 2013

Detection of isocitrate dehydrogenase 1 mutation R132H in myelodysplastic syndrome by mutation-specific antibody and direct sequencing

artículo científico publicado en 2010

Detection of the BRAF V600E mutation in serous ovarian tumors: a comparative analysis of immunohistochemistry with a mutation-specific monoclonal antibody and allele-specific PCR.

artículo científico

Development, characterization, and reversal of acquired resistance to the MEK1 inhibitor selumetinib (AZD6244) in an in vivo model of childhood astrocytoma

artículo científico publicado en 2013

Diagnostics of Paediatric Supratentorial RELA Ependymomas: Integration of information from Histopathology, Genetics, DNA Methylation and Imaging

article

Differential expression of the tumor suppressor A-kinase anchor protein 12 in human diffuse and pilocytic astrocytomas is regulated by promoter methylation

artículo científico publicado en 2013

Disseminating anaplastic brainstem oligodendroglioma associated with allelic loss in the tumor suppressor candidate region D19S246 of chromosome 19 mimicking an inflammatory central nervous system disease in a 9-year-old boy.

artículo científico publicado en 2005

Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling

artículo científico publicado en 2012

Distribution of EGFR amplification, combined chromosome 7 gain and chromosome 10 loss, and TERT promoter mutation in brain tumors and their potential for the reclassification of IDHwt astrocytoma to glioblastoma

scientific article published on 05 September 2018

Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system

artículo científico publicado en 2013

EGR-1 is regulated by N-methyl-D-aspartate-receptor stimulation and associated with patient survival in human high grade astrocytomas

artículo científico publicado en 2008

EMBR-01. MOLECULAR AND CLINICAL HETEROGENEITY IN HISTOLOGICALLY-DIAGNOSED CNS-PNET PATIENTS PROSPECTIVELY TREATED AS A SINGLE ENTITY: A REPORT FROM THE CHILDREN’S ONCOLOGY GROUP ACNS0332 TRIAL.

artículo científico publicado en 2018

EMBR-02. RECURRENT HOMOZYGOUS DELETION OF DROSHA AND MICRODUPLICATION OF PDE4DIP CONTAINING THE ANCESTRAL DUF1220 DOMAIN IN PINEOBLASTOMA

EMBR-15. DIAGNOSTIC RE-EVALUATION AND POOLED CLINICAL DATA ANALYSIS OF PATIENTS WITH PREVIOUS DIAGNOSIS OF CNS-PNET

EPEN-24. YAP1 FUSION PROTEINS MEDIATE ONCOGENIC ACTIVITY IN EPENDYMOMA VIA INTERACTION WITH TEAD TRANSCRIPTION FACTORS.

artículo científico publicado en 2018

EPN-12PEDIATRIC SUPRATENTORIAL EPENDYMOMA: COMPARISON BETWEEN IMMUNOHISTOCHEMISTRY, FISH AND DNA METHYLATION ANALYSIS FOR RELA REARRANGEMENT AND HISTOLOGICAL CORRELATION.

artículo científico publicado en 2016

EPN-30YAP1-MAMLD1 FUSIONS ALONE ARE SUFFICIENT TO FORM SUPRATENTORIAL EPENDYMOMA-LIKE TUMORS IN MICE.

artículo científico publicado en 2016

EPND-13. YAP1-MAMLD1 FUSIONS ALONE ARE SUFFICIENT TO FORM SUPRATENTORIAL EPENDYMOMA-LIKE TUMORS IN MICE.

artículo científico publicado en 2017

Elevated HLA-E levels in human glioblastomas but not in grade I to III astrocytomas correlate with infiltrating CD8+ cells.

artículo científico publicado en 2007

Epithelioid glioblastomas stratify into established diagnostic subsets upon integrated molecular analysis.

artículo científico publicado en 2017

Erratum to: Gliomatosis cerebri: no evidence for a separate brain tumor entity

artículo científico publicado en 2016

Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing

artículo científico publicado en 2016

Evidence of H3 K27M mutations in posterior fossa ependymomas

artículo científico publicado en 2016

Expression pattern of the water channel aquaporin-4 in human gliomas is associated with blood-brain barrier disturbance but not with patient survival

artículo científico publicado en 2007

Extensive Molecular and Clinical Heterogeneity in Patients With Histologically Diagnosed CNS-PNET Treated as a Single Entity: A Report From the Children's Oncology Group Randomized ACNS0332 Trial

artículo científico publicado en 2018

FGFR3 overexpression is a useful detection tool for FGFR3 fusions and sequence variations in glioma

artículo científico publicado en 2020

Farewell to oligoastrocytoma: in situ molecular genetics favor classification as either oligodendroglioma or astrocytoma

artículo científico publicado en 2014

Feasibility of real-time molecular profiling for patients with newly diagnosed glioblastoma without MGMT promoter-hypermethylation - the NCT Neuro Master Match (N2M2) pilot study

artículo científico publicado en 2017

GENE-13. PEDIATRIC MENINGIOMAS ARE CHARACTERIZED BY DISTINCT METHYLATION PROFILES DIFFERENT FROM ADULT MENINGIOMAS

artículo científico publicado en 2019

GENO-20NOVEL CANDIDATE ONCOGENIC DRIVERS IN PINEOBLASTOMA.

artículo científico publicado en 2015

GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3.

artículo científico publicado en 2014

Gain of 12p encompassing CCND2 is associated with gemistocytic histology in IDH mutant astrocytomas

artículo científico publicado en 2016

Genetic Alterations in Gliosarcoma and Giant Cell Glioblastoma

artículo científico publicado en 2015

Genetic and epigenetic characterization of posterior pituitary tumors

artículo científico publicado en 2021

Glial papillary tumour of the spinal cord with SMARCB1/INI1-loss and favourable long-term outcome

artículo científico publicado en 2017

Gliomatosis cerebri: no evidence for a separate brain tumor entity

artículo científico publicado en 2015

H3-/IDH-wild type pediatric glioblastoma is comprised of molecularly and prognostically distinct subtypes with associated oncogenic drivers

artículo científico publicado en 2017

HG-68COMBINED ALTERATIONS IN MAPK PATHWAY GENES, CDKN2A/B AND ATRX CHARACTERIZE ANAPLASTIC PILOCYTIC ASTROCYTOMA.

artículo científico publicado en 2016

HGG-24. MOLECULAR, PATHOLOGICAL, RADIOLOGICAL AND IMMUNE PROFILING OF NON-BRAINSTEM PAEDIATRIC HIGH GRADE GLIOMA FROM THE HERBY PHASE II RANDOMISED TRIAL

artículo científico publicado en 2018

Histologically distinct neuroepithelial tumors with histone 3 G34 mutation are molecularly similar and comprise a single nosologic entity

artículo científico publicado en 2015

Histone 3.3 hotspot mutations in conventional osteosarcomas: a comprehensive clinical and molecular characterization of six H3F3A mutated cases

artículo científico publicado en 2017

IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO.

artículo científico publicado en 2015

IDH1 R132H mutation is a rare event in myeloproliferative neoplasms as determined by a mutation specific antibody

artículo científico publicado en 2010

Immunohistochemical analysis of 1844 human epithelial and haematopoietic tumours and sarcomas for IDH1R132H mutation.

artículo científico publicado en 2011

Immunohistochemical detection of the BRAF V600E-mutated protein in papillary thyroid carcinoma.

artículo científico publicado en 2012

Immunohistochemical testing of BRAF V600E status in 1,120 tumor tissue samples of patients with brain metastases

artículo científico publicado en 2012

Immunohistochemistry is highly sensitive and specific for the detection of V600E BRAF mutation in melanoma.

artículo científico publicado en 2013

Improved molecular classification of serrated lesions of the colon by immunohistochemical detection of BRAF V600E.

artículo científico publicado en 2013

Increased levels of 2-hydroxyglutarate in AML patients with IDH1-R132H and IDH2-R140Q mutations

artículo científico publicado en 2010

Infant high grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes

scientific article published on 01 April 2020

Infratentorial IDH-mutant astrocytoma is a distinct subtype

artículo científico publicado en 2020

Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma

artículo científico publicado en 2014

Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers

artículo científico publicado en 2015

Integrated molecular characterization of IDH-mutant glioblastomas

artículo científico publicado en 2018

Intramedullary Solitary Fibrous Tumor--A Benign Form of Hemangiopericytoma? Case Report and Review of the Literature

artículo científico publicado en 2015

Invited Review: DNA methylation-based classification of paediatric brain tumours

artículo científico publicado en 2020

Isocitrate dehydrogenase 1 mutant R132H sensitizes glioma cells to BCNU-induced oxidative stress and cell death

artículo científico publicado en 2013

Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course

artículo científico publicado en 2019

LGG-11. REGULATION OF ONCOGENE-INDUCED SENESCENCE IN PILOCYTIC ASTROCYTOMA.

artículo científico publicado en 2018

LGG-20. MOLECULARLY-DEFINED DIFFUSE LEPTOMENINGEAL GLIONEURONAL TUMOR (DLGNT) COMPRISES TWO SUBGROUPS WITH DISTINCT CLINICAL AND GENETIC FEATURES

LOC283731 promoter hypermethylation prognosticates survival after radiochemotherapy in IDH1 wild-type glioblastoma patients

artículo científico publicado en 2016

Lack of BRAF V600E protein expression in primary central nervous system lymphoma

artículo científico publicado en 2013

Location-Dependent Patient Outcome and Recurrence Patterns in IDH1-Wildtype Glioblastoma

Low-grade epilepsy-associated neuroepithelial tumours - the 2016 WHO classification

artículo científico publicado en 2016

MAP kinase activity supported by BRAF (V600E) mutation rather than gene amplification is associated with ETV1 expression in melanoma brain metastases

artículo científico publicado en 2014

MB-17NOVEL CANDIDATE ONCOGENIC DRIVERS IN PINEOBLASTOMA.

artículo científico publicado en 2015

MB-26SHH DESMOPLASTIC/NODULAR MEDULLOBLASTOMA AND GORLIN SYNDROME IN THE SETTING OF DOWN SYNDROME: CASE REPORT WITH MOLECULAR PROFILING.

artículo científico publicado en 2016

MB-30OUTCOME OF CLINICAL “STANDARD RISK” MEDULLOBLASTOMA WITH CMYC AMPLIFICATION: A CASE REPORT AND ASSESSMENT OF THE LITERATURE.

artículo científico publicado en 2016

MEDU-38. NEXT GENERATION MOLECULAR CHARACTERIZATION OF LOCALLY RECURRENT WNT PATHWAY MEDULLOBLASTOMA: A CASE REPORT.

artículo científico publicado en 2017

MPTH-15MOLECULAR RECLASSIFICATION OF CNS-PRIMITIVE NEUROECTODERMAL TUMORS INTO WELL-KNOWN AND NOVEL TUMOR ENTITIES.

artículo científico publicado en 2015

MRI Features of Histologically Diagnosed Supratentorial Primitive Neuroectodermal Tumors and Pineoblastomas in Correlation with Molecular Diagnoses and Outcomes: A Report from the Children's Oncology Group ACNS0332 Trial

scientific article published on 10 October 2019

Machine learning analysis of DNA methylation profiles distinguishes primary lung squamous cell carcinomas from head and neck metastases

scientific article published on 01 September 2019

Malignant Transformation of a Dysembryoplastic Neuroepithelial Tumor (DNET) Characterized by Genome-Wide Methylation Analysis

artículo científico publicado en 2016

Malignant astrocytomas of elderly patients lack favorable molecular markers: an analysis of the NOA-08 study collective

artículo científico publicado en 2013

Melanotic tumors of the nervous system are characterized by distinct mutational, chromosomal and epigenomic profiles

artículo científico publicado en 2014

Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein

artículo científico publicado en 2013

Methylation array profiling of adult brain tumours: diagnostic outcomes in a large, single centre

Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups

artículo científico publicado en 2016

Methylation-based classification of benign and malignant peripheral nerve sheath tumors

artículo científico publicado en 2016

Modulation of TGF-beta activity by latent TGF-beta-binding protein 1 in human malignant glioma cells

artículo científico publicado en 2009

Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups

artículo científico publicado en 2015

Molecular Transition of an Adult Low-Grade Brain Tumor to an Atypical Teratoid/Rhabdoid Tumor Over a Time-Course of 14 Years

artículo científico

Molecular profiling of long-term survivors identifies a subgroup of glioblastoma characterized by chromosome 19/20 co-gain

artículo científico publicado en 2015

Molecular, Pathological, Radiological, and Immune Profiling of Non-brainstem Pediatric High-Grade Glioma from the HERBY Phase II Randomized Trial.

artículo científico publicado en 2018

Molecularly defined diffuse leptomeningeal glioneuronal tumor (DLGNT) comprises two subgroups with distinct clinical and genetic features.

artículo científico publicado en 2018

Monoclonal antibody specific for IDH1 R132H mutation

artículo científico publicado en 2009

Multiple thromboembolic events in fetofetal transfusion syndrome in triplets contributing to the understanding of pathogenesis of hydranencephaly in combination with polymicrogyria

artículo científico publicado en 2006

Mutant BRAF V600E protein in ganglioglioma is predominantly expressed by neuronal tumor cells

artículo científico publicado en 2013

Mutation specific antibodies: tool or dinosaur?

artículo científico publicado en 2012

Mutation-specific IDH1 antibody differentiates oligodendrogliomas and oligoastrocytomas from other brain tumors with oligodendroglioma-like morphology.

artículo científico publicado en 2010

NEXT-GENERATION NEUROPATHOLOGY - IMPROVING DIAGNOSTIC ACCURACY FOR BRAIN TUMORS USING DNA METHYLATION ARRAY-BASED MOLECULAR PROFILING.

artículo científico publicado en 2014

NFM-11. PEDIATRIC MENINGIOMAS ARE MOLECULARLY DISTINCT FROM ADULT COUNTERPARTS

article published in 2018

Neurofibromin specific antibody differentiates malignant peripheral nerve sheath tumors (MPNST) from other spindle cell neoplasms

artículo científico publicado en 2014

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

artículo científico publicado en 2016

Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study

artículo científico publicado en 2016

Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets

artículo científico publicado en 2015

No evidence for BRAF-V600E mutations in gastroeosophageal tumors: results from a high-throughput analysis of 534 cases using a mutation-specific antibody

artículo científico publicado en 2013

No prognostic value of IDH1 mutations in a series of 100 WHO grade II astrocytomas

artículo científico publicado en 2012

Novel, improved grading system(s) for IDH-mutant astrocytic gliomas

artículo científico publicado en 2018

Nuclear relocation of STAT6 reliably predicts NAB2-STAT6 fusion for the diagnosis of solitary fibrous tumour

artículo científico publicado en 2014

PCR- and restriction endonuclease-based detection of IDH1 mutations

artículo científico publicado en 2009

PDCT-05. MOLECULAR DIAGNOSTICS REVEAL 60% HIGHER SURVIVAL FOR MOLECULARLY-VERIFIED VERSUS HISTOPATHOLOGICALLY-DIAGNOSED PEDIATRIC SUPRATENTORIAL CENTRAL NERVOUS SYSTEM EMBRYONAL TUMORS AND PINEOBLASTOMAS; A REPORT FROM THE CHILDREN’S ONCOLOGY GROUP

PDTM-38. PEDIATRIC MENINGIOMAS ARE CHARACTERIZED BY DISTINCT METHYLATION PROFILES DIFFERENT FROM ADULT MENINGIOMAS

PDTM-47. CHARACTERIZATION OF THE SENESCENCE-ASSOCIATED SECRETORY PHENOTYPE IN PILOCYTIC ASTROCYTOMA AND ITS ROLE IN ONCOGENE-INDUCED SENESCENCE

PNR-21FOUR NEW BRAIN TUMOR ENTITIES EMERGE FROM MOLECULAR CLASSIFICATION OF CNS PNETs

artículo científico publicado en 2016

PNR-33MOLECULAR RE-EVALUATION OF INSTITUTIONALLY DIAGNOSED CNS-PNETS: CLINICAL CONSEQUENCES OF CONFINED DIAGNOSTIC GROUPS.

artículo científico publicado en 2016

PROGNOSTIC AND PREDICTIVE BIOMARKER-BASED SUBGROUPS IN THE NOA-04 TRIAL.

artículo científico publicado en 2014

Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo

artículo científico publicado en 2017

Papillary Tumor of the Pineal Region: A Distinct Molecular Entity

artículo científico publicado en 2015

Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA

artículo científico publicado en 2019

Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas

artículo científico publicado en 2010

Pediatric Targeted Therapy: Clinical Feasibility of Personalized Diagnostics in Children with Relapsed and Progressive Tumors

artículo científico publicado en 2015

Pediatric atypical choroid plexus papilloma reconsidered: increased mitotic activity is prognostic only in older children

Pericytes/vessel-associated mural cells (VAMCs) are the major source of key epithelial-mesenchymal transition (EMT) factors SLUG and TWIST in human glioma.

artículo científico publicado en 2018

Pitfalls in the assessment of MGMT expression and in its correlation with survival in diffuse astrocytomas: proposal of a feasible immunohistochemical approach.

artículo científico publicado en 2007

Poorly differentiated chordoma with SMARCB1/INI1 loss: a distinct molecular entity with dismal prognosis

artículo científico publicado en 2016

Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience.

artículo científico publicado en 2018

Preoperative assessment of haemostasis in patients undergoing stereotactic brain biopsy.

artículo científico publicado en 2018

Primary glioblastoma cultures: can profiling of stem cell markers predict radiotherapy sensitivity?

artículo científico publicado en 2014

Printed peptide arrays identify prognostic TNC serumantibodies in glioblastoma patients

artículo científico publicado en 2015

Prognostic value of the extent of resection in supratentorial WHO grade II astrocytomas stratified for IDH1 mutation status: a single-center volumetric analysis

artículo científico publicado en 2016

Proximity ligation assay evaluates IDH1R132H presentation in gliomas

artículo científico publicado en 2015

Radiogenomics of Glioblastoma: Machine Learning-based Classification of Molecular Characteristics by Using Multiparametric and Multiregional MR Imaging Features

artículo científico publicado en 2016

Radiomic subtyping improves disease stratification beyond key molecular, clinical and standard imaging characteristics in patients with glioblastoma

artículo científico publicado en 2017

Rathke's cleft cyst rupture as potential initial event of a secondary perifocal lymphocytic hypophysitis: proposal of an unusual pathogenetic event and review of the literature

artículo científico publicado en 2008

Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors

artículo científico publicado en 2021

Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma

artículo científico publicado en 2018

Response to trametinib treatment in progressive pediatric low-grade glioma patients

artículo científico publicado en 2020

Risk factors for glioblastoma therapy associated complications

artículo científico publicado en 2015

Rosette-forming glioneuronal tumors share a distinct DNA methylation profile and mutations in FGFR1, with recurrent co-mutation of PIK3CA and NF1

scientific article published on 27 June 2019

SHH desmoplastic/nodular medulloblastoma and Gorlin syndrome in the setting of Down syndrome: case report, molecular profiling, and review of the literature

artículo científico publicado en 2016

Sarcoma classification by DNA methylation profiling

artículo científico publicado en 2021

Satisfying your neuro-oncologist: a fast approach to routine molecular glioma diagnostics

artículo científico publicado en 2018

Secondary hematoma expansion in intracerebral hemorrhage during rivaroxaban therapy

artículo científico publicado en 2014

Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations

artículo científico publicado en 2013

Sellar Region Atypical Teratoid/Rhabdoid Tumors (ATRT) in Adults Display DNA Methylation Profiles of the ATRT-MYC Subgroup

artículo científico publicado en 2018

Severe hypoxia and multiple infarctions resembling Creutzfeldt-Jakob disease.

artículo científico publicado en 2008

Somatic mutations of DICER1 and KMT2D are frequent in intraocular medulloepitheliomas.

artículo científico publicado en 2016

Spatial transcriptome analysis reveals Notch pathway-associated prognostic markers in IDH1 wild-type glioblastoma involving the subventricular zone

artículo científico publicado en 2016

Spinal metastasis of gliosarcoma: array-based comparative genomic hybridization for confirmation of metastatic spread

artículo científico publicado en 2014

Stem-cell-like glioma cells are resistant to TRAIL/Apo2L and exhibit down-regulation of caspase-8 by promoter methylation

artículo científico publicado en 2009

Survival according to BRAF-V600 tumor mutations--an analysis of 437 patients with primary melanoma

artículo científico publicado en 2014

Synchronous pituitary adenoma and pituicytoma

artículo científico publicado en 2015

TERT Promoter Mutations and Risk of Recurrence in Meningioma

artículo científico publicado en 2015

TERT promoter mutation and chromosome 6 loss define a high-risk subtype of ependymoma evolving from posterior fossa subependymoma

artículo científico publicado en 2021

Tall cell papillary thyroid carcinoma: new diagnostic criteria and mutations in BRAF and TERT.

artículo científico

Targeting the BRAF V600E mutation in multiple myeloma

artículo científico publicado en 2013

Temozolomide chemotherapy versus radiotherapy in high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study

artículo científico publicado en 2016

The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma

artículo científico publicado en 2018

The case for DNA methylation based molecular profiling to improve diagnostic accuracy for central nervous system embryonal tumors (not otherwise specified) in adults

artículo científico publicado en 2017

The embryonic stem cell factor UTF1 serves as a reliable diagnostic marker for germinomas

artículo científico publicado en 2014

The evolution of the anaplastic cerebellar liponeurocytoma: case report and review of the literature

artículo científico

The miR-139-5p regulates proliferation of supratentorial paediatric low-grade gliomas by targeting the PI3K/AKT/mTORC1 signalling

artículo científico publicado en 2018

The whole-genome landscape of medulloblastoma subtypes

artículo científico publicado en 2017

Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities

artículo científico publicado en 2019

Tumour necrosis factor receptor superfamily member 9 (TNFRSF9) is up-regulated in reactive astrocytes in human gliomas

artículo científico publicado en 2015

Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas.

artículo científico publicado en 2009

VE1 immunohistochemistry in pituitary adenomas is not associated with BRAF V600E mutation

artículo científico publicado en 2013

Validation of a Manual Protocol for BRAF V600E Mutation-specific Immunohistochemistry

artículo científico publicado en 2015

Voxel-wise radiogenomic mapping of tumor location with key molecular alterations in patients with glioma

artículo científico publicado en 2018

WHO 2016 Classification of gliomas

artículo científico publicado en 2017

YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis

scientific article published on 02 September 2019

cIMPACT-NOW (the consortium to inform molecular and practical approaches to CNS tumor taxonomy): a new initiative in advancing nervous system tumor classification

artículo científico publicado en 2016

cIMPACT-NOW update 1: Not Otherwise Specified (NOS) and Not Elsewhere Classified (NEC).

artículo científico publicado en 2018

cIMPACT-NOW update 2: diagnostic clarifications for diffuse midline glioma, H3 K27M-mutant and diffuse astrocytoma/anaplastic astrocytoma, IDH-mutant

artículo científico publicado en 2018

p53-Dependent Nestin Regulation Links Tumor Suppression to Cellular Plasticity in Liver Cancer.

artículo científico publicado en 2016