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Lista de obras de Henderik W Frijlink

A Design of Experiment approach to predict product and process parameters for a spray dried influenza vaccine

artículo científico publicado en 2016

A Novel Ileocolonic Release Peppermint Oil Capsule for Treatment of Irritable Bowel Syndrome: A Phase I Study in Healthy Volunteers

artículo científico publicado en 2018

A centrifuge method to measure particle cohesion forces to substrate surfaces: the use of a force distribution concept for data interpretation

artículo científico publicado en 2010

A comparison between spray drying and spray freeze drying to produce an influenza subunit vaccine powder for inhalation.

artículo científico publicado en 2010

A critical evaluation of the relevant parameters for drug redispersion from adhesive mixtures during inhalation.

artículo científico publicado en 2005

A density-based segmentation for 3D images, an application for X-ray micro-tomography.

artículo científico publicado en 2012

A gastrointestinal simulation system for dissolution of oral solid dosage forms before and after Roux-en-Y gastric bypass

scientific article published on 08 February 2018

A levodopa dry powder inhaler for the treatment of Parkinson's disease patients in off periods

artículo científico publicado en 2015

A new strategy to stabilize oxytocin in aqueous solutions: I. The effects of divalent metal ions and citrate buffer.

artículo científico publicado en 2011

A new strategy to stabilize oxytocin in aqueous solutions: II. Suppression of cysteine-mediated intermolecular reactions by a combination of divalent metal ions and citrate

artículo científico publicado en 2012

A novel aerosol generator for homogenous distribution of powder over the lungs after pulmonary administration to small laboratory animals

artículo científico publicado en 2014

A novel dissolution method relevant to intestinal release behaviour and its application in the evaluation of modified release mesalazine products

scientific article published on 04 October 2006

A proposed definition of the 'activity' of surface sites on lactose carriers for dry powder inhalation

artículo científico publicado en 2014

A systematic review and meta-analysis of microbial contamination of parenteral medication prepared in a clinical versus pharmacy environment

scientific article published on 25 January 2019

A user-friendly model for spray drying to aid pharmaceutical product development.

artículo científico publicado en 2013

Addition of Pullulan to Trehalose Glasses Improves the Stability of β-Galactosidase at High Moisture Conditions

artículo científico publicado en 2017

Adenosine dry powder inhalation for bronchial challenge testing, part 1: inhaler and formulation development and in vitro performance testing.

artículo científico publicado en 2013

Adenosine dry powder inhalation for bronchial challenge testing, part 2: proof of concept in asthmatic subjects.

artículo científico publicado en 2014

Advax augments B and T cell responses upon influenza vaccination via the respiratory tract and enables complete protection of mice against lethal influenza virus challenge

article

Aerosolization of tobramycin (TOBI) with the PARI LC PLUS reusable nebulizer: which compressor to use? Comparison of the CR60 to the PortaNeb compressor.

artículo científico publicado en 2008

Air classifier technology (ACT) in dry powder inhalation Part 4. Performance of air classifier technology in the Novolizer multi-dose dry powder inhaler.

artículo científico publicado en 2006

Air classifier technology (ACT) in dry powder inhalation. Part 2. The effect of lactose carrier surface properties on the drug-to-carrier interaction in adhesive mixtures for inhalation.

artículo científico publicado en 2003

An investigation into the predictive value of cascade impactor results for side effects of inhaled salbutamol.

artículo científico publicado en 2004

Anomalous dissolution behaviour of tablets prepared from sugar glass-based solid dispersions.

artículo científico publicado en 2004

Application of process analytical technology in tablet process development using NIR spectroscopy: blend uniformity, content uniformity and coating thickness measurements

artículo científico publicado en 2008

Aspartate buffer and divalent metal ions affect oxytocin in aqueous solution and protect it from degradation.

artículo científico publicado en 2013

Associations of AMP and adenosine induced dyspnea sensation to large and small airways dysfunction in asthma

scientific article published on 28 January 2019

Automated Filling Equipment Allows Increase in the Maximum Dose to Be Filled in the Cyclops® High Dose Dry Powder Inhalation Device While Maintaining Dispersibility

artículo científico publicado en 2020

Benefits of different drug formulations in psychopharmacology.

artículo científico publicado en 2003

Blending of agglomerates into powders 1: Quantification of abrasion rate.

artículo científico publicado en 2009

Bottom-Up Preparation Techniques for Nanocrystals of Lipophilic Drugs ⬇️

artículo científico publicado el 18 de noviembre de 2010

Breaking of scored tablets: a review.

artículo científico publicado en 2002

Bronchial Provocation Testing Can Be Improved by Using Dry Powder Adenosine Instead of Nebulized AMP.

artículo científico publicado en 2017

Can 'extrafine' dry powder aerosols improve lung deposition?

artículo científico publicado en 2015

Can Patients with Parkinson's Disease Use Dry Powder Inhalers during Off Periods?

artículo científico publicado en 2015

Can tobramycin inhalation be improved with a jet nebulizer?

scientific article published on 01 December 1999

Challenges for pulmonary delivery of high powder doses

artículo científico publicado en 2018

Challenging the Two-Minute Tidal Breathing Challenge Test ⬇️

artículo científico publicado el 19 de marzo de 2013

Characterisation of high dose aerosols from dry powder inhalers ⬇️

artículo científico publicado el 19 de agosto de 2012

Characterization of inhalation aerosols: a critical evaluation of cascade impactor analysis and laser diffraction technique.

artículo científico publicado en 2002

Characterization of the molecular distribution of drugs in glassy solid dispersions at the nano-meter scale, using differential scanning calorimetry and gravimetric water vapour sorption techniques.

artículo científico publicado en 2006

Clinical efficacy, safety and pharmacokinetics of a newly developed controlled release morphine sulphate suppository in patients with cancer pain

artículo científico publicado en 2000

ColoPulse tablets perform comparably in healthy volunteers and Crohn's patients and show no influence of food and time of food intake on bioavailability

artículo científico publicado en 2013

Compaction mechanism and tablet strength of unlubricated and lubricated (silicified) microcrystalline cellulose.

artículo científico publicado en 2005

Comparative in vitro evaluation of four corticosteroid metered dose inhalers: Consistency of delivered dose and particle size distribution.

artículo científico publicado en 2009

Comparison of adjuvants for a spray freeze-dried whole inactivated virus influenza vaccine for pulmonary administration.

artículo científico publicado en 2015

Concepts for increasing gentamicin release from handmade bone cement beads.

artículo científico publicado en 2009

Controlled crystallization of the lipophilic drug fenofibrate during freeze-drying: elucidation of the mechanism by in-line Raman spectroscopy.

artículo científico publicado en 2010

Copper-Heparin Inhalation Therapy To Repair Emphysema: A Scientific Rationale

artículo científico publicado en 2019

Cross border, highly individualised treatment of a patient with challenging extensively drug-resistant tuberculosis

artículo científico publicado en 2018

Cyclodextrin-facilitated bioconversion of 17 beta-estradiol by a phenoloxidase from Mucuna pruriens cell cultures

scientific article published on 01 January 1990

Design and application of a new modular adapter for laser diffraction characterization of inhalation aerosols.

artículo científico publicado en 2002

Design and fungicidal activity of mucoadhesive lactoferrin tablets for the treatment of oropharyngeal candidosis

artículo científico publicado en 2002

Design and in vitro performance testing of multiple air classifier technology in a new disposable inhaler concept (Twincer) for high powder doses.

artículo científico publicado en 2006

Determination of cyclodextrins in biological fluids by high-performance liquid chromatography with negative colorimetric detection using post-column complexation with phenolphthalein

artículo científico publicado en 1987

Development and potential application of an oral ColoPulse infliximab tablet with colon specific release: A feasibility study.

artículo científico publicado en 2016

Development of a dried influenza whole inactivated virus vaccine for pulmonary immunization.

artículo científico publicado en 2011

Development of a thermostable spray dried outer membrane vesicle pertussis vaccine for pulmonary immunization

scientific article published on 24 July 2018

Development of a zero-order sustained-release tablet containing mesalazine and budesonide intended to treat the distal gastrointestinal tract in inflammatory bowel disease.

artículo científico publicado en 2016

Development of an Orodispersible Film Containing Stabilized Influenza Vaccine

scientific article published on 08 March 2020

Development of novel zero-order release budesonide tablets for the treatment of ileo-colonic inflammatory bowel disease and comparison with formulations currently used in clinical practice

article

Development of stable influenza vaccine powder formulations: challenges and possibilities

artículo científico publicado en 2008

Developments and strategies for inhaled antibiotic drugs in tuberculosis therapy: a critical evaluation.

artículo científico publicado en 2013

Developments in the formulation and delivery of spray dried vaccines

artículo científico publicado en 2017

Devices and formulations for pulmonary vaccination.

artículo científico publicado en 2013

Dispersibility and Storage Stability Optimization of High Dose Isoniazid Dry Powder Inhalation Formulations with L-Leucine or Trileucine

artículo científico publicado en 2019

Drug content effects on the dispersion performance of adhesive mixtures for inhalation

artículo científico publicado en 2013

Drug output of unvented jet nebulizers as a function of time ⬇️

artículo científico publicado el 12 de mayo de 2003

Dry influenza vaccines: towards a stable, effective and convenient alternative to conventional parenteral influenza vaccination

artículo científico publicado en 2016

Dry powder inhalation of antibiotics in cystic fibrosis therapy: part 2. Inhalation of a novel colistin dry powder formulation: a feasibility study in healthy volunteers and patients.

artículo científico publicado en 2002

Dry powder inhalation of colistin in cystic fibrosis patients: a single dose pilot study.

artículo científico publicado en 2006

Dry powder inhalation of colistin sulphomethate in healthy volunteers: A pilot study.

artículo científico publicado en 2006

Dry powder inhalation versus wet nebulisation delivery of antibiotics in cystic fibrosis patients.

artículo científico publicado en 2007

Dry powder inhalation: past, present and future

artículo científico publicado en 2016

Effect of an external resistance to airflow on the inspiratory flow curve.

artículo científico publicado en 2002

Effect of drug-carrier interaction on the dissolution behavior of solid dispersion tablets.

artículo científico publicado en 2010

Effect of inhaler design variables on paediatric use of dry powder inhalers

artículo científico publicado en 2014

Effect of nebulized colistin sulphate and colistin sulphomethate on lung function in patients with cystic fibrosis: a pilot study.

artículo científico publicado en 2004

Efficacy and Safety of On-Demand Use of 2 Treatments Designed for Different Etiologies of Female Sexual Interest/Arousal Disorder: 3 Randomized Clinical Trials.

artículo científico publicado en 2017

Efficacy of a new pulmonary cyclosporine a powder formulation for prevention of transplant rejection in rats

artículo científico publicado en 2009

Efficient production of solid dispersions by spray drying solutions of high solid content using a 3-fluid nozzle

artículo científico publicado en 2017

Enhanced pulmonary immunization with aerosolized inactivated influenza vaccine containing delta inulin adjuvant.

artículo científico publicado en 2014

Evaluating the immunogenicity and safety of a BiondVax-developed universal influenza vaccine (Multimeric-001) either as a standalone vaccine or as a primer to H5N1 influenza vaccine: Phase IIb study protocol

artículo científico publicado en 2017

Evaluation of monophosphoryl lipid A as adjuvant for pulmonary delivered influenza vaccine.

artículo científico publicado en 2013

Extrafine compared to non-extrafine particle inhaled corticosteroids in smokers and ex-smokers with asthma.

artículo científico publicado en 2017

Feasibility of nonvolatile buffers in capillary electrophoresis-electrospray ionization-mass spectrometry of proteins.

artículo científico publicado en 2004

Film coated tablets (ColoPulse technology) for targeted delivery in the lower intestinal tract: influence of the core composition on release characteristics.

artículo científico publicado en 2010

Formulation and process development of (recombinant human) deoxyribonuclease I as a powder for inhalation

artículo científico publicado en 2009

Gastro-intestinal delivery of influenza subunit vaccine formulation adjuvanted with Gram-positive enhancer matrix (GEM) particles.

artículo científico publicado en 2010

Gastrointestinal pH and Transit Time Profiling in Healthy Volunteers Using the IntelliCap System Confirms Ileo-Colonic Release of ColoPulse Tablets

artículo científico publicado en 2015

Genotype scores predict drug efficacy in subtypes of female sexual interest/arousal disorder: A double-blind, randomized, placebo-controlled cross-over trial

artículo científico publicado en 2018

Hollow filler-binders as excipients for direct compaction.

artículo científico publicado en 2003

How sugars protect proteins in the solid state and during drying (review): Mechanisms of stabilization in relation to stress conditions.

artículo científico publicado en 2017

Identifying critical process steps to protein stability during spray drying using a vibrating mesh or a two-fluid nozzle

scientific article published on 03 December 2018

Improved dissolution behavior of lipophilic drugs by solid dispersions: the production process as starting point for formulation considerations.

artículo científico publicado en 2011

Improved storage stability and immunogenicity of hepatitis B vaccine after spray-freeze drying in presence of sugars

artículo científico publicado en 2014

In vitro evaluation of the DP-4M PennCentury insufflator.

artículo científico publicado en 2014

In vitro performance testing of the novel Medspray wet aerosol inhaler based on the principle of Rayleigh break-up

artículo científico publicado en 2007

In-line near infrared spectroscopy during freeze-drying as a tool to measure efficiency of hydrogen bond formation between protein and sugar, predictive of protein storage stability

artículo científico publicado en 2015

Incorporation of lipophilic drugs in sugar glasses by lyophilization using a mixture of water and tertiary butyl alcohol as solvent.

artículo científico publicado en 2004

Increased drug load and polymer compatibility of bilayered orodispersible films.

artículo científico publicado en 2017

Increased podophyllotoxin production in Podophyllum hexandrum cell suspension cultures after feeding coniferyl alcohol as a β-cyclodextrin complex

scientific article published on 01 July 1990

Influence of Miscibility of Protein-Sugar Lyophilizates on Their Storage Stability.

artículo científico publicado en 2016

Influenza antigen-sparing by immune stimulation with Gram-positive enhancer matrix (GEM) particles

scientific article published on 12 October 2010

Inhalation of tobramycin in cystic fibrosis. Part 2: optimization of the tobramycin solution for a jet and an ultrasonic nebulizer.

artículo científico publicado en 1999

Intranasal delivery of influenza subunit vaccine formulated with GEM particles as an adjuvant.

artículo científico publicado en 2010

Inulin as filler-binder for tablets prepared by direct compaction

artículo científico publicado en 2002

Inulin is a promising cryo- and lyoprotectant for PEGylated lipoplexes.

artículo científico publicado en 2005

Inulin sugar glasses preserve the structural integrity and biological activity of influenza virosomes during freeze-drying and storage.

artículo científico publicado en 2007

Inulin, a flexible oligosaccharide I: Review of its physicochemical characteristics

artículo científico publicado en 2015

Inulin, a flexible oligosaccharide. II: Review of its pharmaceutical applications

artículo científico publicado en 2015

Investigations into the stabilisation of drugs by sugar glasses: I. Tablets prepared from stabilised alkaline phosphatase.

artículo científico publicado en 2002

Investigations into the stabilization of drugs by sugar glasses: III. The influence of various high-pH buffers

artículo científico publicado el 1 de septiembre de 2003

Kinetic energy density and agglomerate abrasion rate during blending of agglomerates into powders.

artículo científico publicado en 2011

Lactose as a carrier for inhalation products: breathing new life into an old carrier. Preface

scientific article published on 11 November 2011

Location-dependent analysis of porosity and pore direction in tablets

scientific article published on 03 August 2005

Low temperature extruded implants based on novel hydrophilic multiblock copolymer for long-term protein delivery ⬇️

artículo científico publicado el 23 de mayo de 2013

NIR spectroscopy for the in-line monitoring of a multicomponent formulation during the entire freeze-drying process.

artículo científico publicado en 2014

Nanoparticle Formulation of a Poorly Soluble Cannabinoid Receptor 1 Antagonist Improves Absorption by Rat and Human Intestine ⬇️

artículo científico publicado el 3 de junio de 2013

Needle-free influenza vaccination.

artículo científico publicado en 2010

New mechanisms to explain the effects of added lactose fines on the dispersion performance of adhesive mixtures for inhalation

artículo científico publicado en 2014

Oral ileocolonic drug delivery by the colopulse-system: a bioavailability study in healthy volunteers.

artículo científico publicado en 2010

Orodispersible films based on blends of trehalose and pullulan for protein delivery

artículo científico publicado en 2018

Orodispersible films in individualized pharmacotherapy: The development of a formulation for pharmacy preparations.

artículo científico publicado en 2014

Oromucosal film preparations: points to consider for patient centricity and manufacturing processes.

artículo científico publicado en 2015

Ovalbumin-containing core-shell implants suitable to obtain a delayed IgG1 antibody response in support of a biphasic pulsatile release profile in mice

artículo científico publicado en 2018

Passive inhalation of dry powder influenza vaccine formulations completely protects chickens against H5N1 lethal viral challenge

artículo científico publicado en 2018

Personalized Medicine in Pediatrics: The Clinical Potential of Orodispersible Films.

artículo científico publicado en 2016

Pharmacoeconomic review of recombinant human DNase in the management of cystic fibrosis.

artículo científico publicado en 2004

Pharmacokinetics of a prototype formulation of sublingual testosterone and a buspirone tablet, versus an advanced combination tablet of testosterone and buspirone in healthy premenopausal women

artículo científico publicado en 2014

Pharmacokinetics of a sustained release formulation of PDGFβ-receptor directed carrier proteins to target the fibrotic liver.

artículo científico publicado en 2017

Physical and immunogenic stability of spray freeze-dried influenza vaccine powder for pulmonary delivery: comparison of inulin, dextran, or a mixture of dextran and trehalose as protectants.

artículo científico publicado en 2013

Plasticisation of amylodextrin by moisture. Consequences for compaction behaviour and tablet properties

scientific article published on 01 October 2001

Plasticisation of amylodextrin by moisture: consequences for drug release from tablets

artículo científico publicado en 2000

Polymeric formulations for drug release prepared by hot melt extrusion: application and characterization.

artículo científico

Polymeric microspheres for the sustained release of a protein-based drug carrier targeting the PDGFβ-receptor in the fibrotic kidney.

artículo científico publicado en 2017

Pore direction in relation to anisotropy of mechanical strength in a cubic starch compact.

artículo científico publicado en 2008

Pore formation in tablets compressed from binary mixtures as a result of deformation and relaxation of particles

scientific article published on 01 March 2002

Pore shape in the sodium chloride matrix of tablets after the addition of starch as a second component.

artículo científico publicado en 2008

Pore size distribution in tablets measured with a morphological sieve.

artículo científico publicado en 2007

Potential of capillary electrophoresis for the monitoring of the stability of placental alkaline phosphatase

artículo científico publicado en 2003

Preparation and physicochemical evaluation of a new tacrolimus tablet formulation for sublingual administration

scientific article published on 30 September 2011

Preparation of drug nanocrystals by controlled crystallization: application of a 3-way nozzle to prevent premature crystallization for large scale production.

artículo científico publicado en 2009

Prerequisites for a dry powder inhaler for children with cystic fibrosis

artículo científico publicado en 2017

Preservation of the immunogenicity of dry-powder influenza H5N1 whole inactivated virus vaccine at elevated storage temperatures.

artículo científico publicado en 2010

Production methods and stabilization strategies for polymer-based nanoparticles and microparticles for parenteral delivery of peptides and proteins.

artículo científico publicado en 2015

Proof-of-concept study on the suitability of 13C-urea as a marker substance for assessment of in vivo behaviour of oral colon-targeted dosage forms.

artículo científico publicado en 2009

Protein release from water-swellable poly(D,L-lactide-PEG)-b-poly(ϵ-caprolactone) implants

scientific article published on 06 January 2015

Pulmonary administration of small interfering RNA: The route to go?

artículo científico publicado en 2016

Pulmonary delivery of an inulin-stabilized influenza subunit vaccine prepared by spray-freeze drying induces systemic, mucosal humoral as well as cell-mediated immune responses in BALB/c mice.

artículo científico publicado en 2007

Quality by design approach for optimizing the formulation and physical properties of extemporaneously prepared orodispersible films

artículo científico publicado en 2015

Quantitative characterization of agglomerate abrasion in a tumbling blender by using the Stokes number approach.

artículo científico publicado en 2012

Rational design of an influenza subunit vaccine powder with sugar glass technology: preventing conformational changes of haemagglutinin during freezing and freeze-drying

artículo científico publicado en 2007

Ready-to-use parenteral amiodarone: a feasibility study towards a long-term stable product formulation

scientific article published on 13 April 2016

Realising the potential of various inhaled airway challenge agents through improved delivery to the lungs

artículo científico publicado en 2018

Recent advances in the fundamental understanding of adhesive mixtures for inhalation.

artículo científico

Review: Local Tumor Necrosis Factor-α Inhibition in Inflammatory Bowel Disease

artículo científico publicado en 2020

Simplifying influenza vaccination during pandemics: sublingual priming and intramuscular boosting of immune responses with heterologous whole inactivated influenza vaccine.

artículo científico publicado en 2014

Single dose sublingual testosterone and oral sildenafil vs. a dual route/dual release fixed dose combination tablet: a pharmacokinetic comparison

artículo científico publicado en 2016

Size and molecular flexibility of sugars determine the storage stability of freeze-dried proteins

artículo científico publicado en 2015

Solid dispersions based on inulin for the stabilisation and formulation of delta 9-tetrahydrocannabinol.

artículo científico publicado en 2004

Spray freeze drying to produce a stable Delta(9)-tetrahydrocannabinol containing inulin-based solid dispersion powder suitable for inhalation.

artículo científico publicado en 2005

Stability of influenza sub-unit vaccine. Does a couple of days outside the refrigerator matter?

scientific article published on 15 August 2005

Stability of lysozyme in aqueous extremolyte solutions during heat shock and accelerated thermal conditions

artículo científico publicado en 2014

Surface-active derivative of inulin (Inutec® SP1) is a superior carrier for solid dispersions with a high drug load

artículo científico publicado en 2011

Tailored protein release from biodegradable poly(ε-caprolactone-PEG)-b-poly(ε-caprolactone) multiblock-copolymer implants.

artículo científico publicado en 2014

Technological and practical challenges of dry powder inhalers and formulations.

artículo científico

Tensile strength of tablets containing two materials with a different compaction behaviour

artículo científico publicado en 2000

The Cyclops for pulmonary delivery of aminoglycosides; a new member of the Twincer™ family.

artículo científico publicado en 2015

The Production of a Stable Infliximab Powder: The Evaluation of Spray and Freeze-Drying for Production

artículo científico publicado en 2016

The Stokes Number Approach to Support Scale-Up and Technology Transfer of a Mixing Process ⬇️

artículo científico publicado el 26 de junio de 2012

The antifibrotic potential of a sustained release formulation of a PDGFβ-receptor targeted rho kinase inhibitor

scientific article published on 22 January 2019

The choice of a compressor for the aerosolisation of tobramycin (TOBI) with the PARI LC PLUS reusable nebuliser.

artículo científico publicado en 2003

The choice of a suitable oligosaccharide to prevent aggregation of PEGylated nanoparticles during freeze thawing and freeze drying.

artículo científico publicado en 2006

The clinical relevance of dry powder inhaler performance for drug delivery.

artículo científico publicado en 2014

The determination of relative path length as a measure for tortuosity in compacts using image analysis

scientific article published on 22 May 2006

The effect of carrier surface and bulk properties on drug particle detachment from crystalline lactose carrier particles during inhalation, as function of carrier payload and mixing time.

artículo científico publicado en 2003

The effect of carrier surface treatment on drug particle detachment from crystalline carriers in adhesive mixtures for inhalation.

artículo científico publicado en 2006

The effect of formulation on spray dried Sabin inactivated polio vaccine

scientific article published on 19 May 2018

The effect of powder blend and tablet structure on drug release mechanisms of hydrophobic starch acetate matrix tablets.

artículo científico publicado en 2005

The effect of the amount of binder liquid on the granulation mechanisms and structure of microcrystalline cellulose granules prepared by high shear granulation.

artículo científico publicado en 2005

The effect of vessel material on granules produced in a high-shear mixer.

artículo científico publicado en 2004

The formation of oxytocin dimers is suppressed by the zinc-aspartate-oxytocin complex

artículo científico publicado en 2013

The influence of particles of a minor component on the matrix strength of sodium chloride

scientific article published on 01 September 2002

The interaction between carrier rugosity and carrier payload, and its effect on drug particle redispersion from adhesive mixtures during inhalation

artículo científico publicado en 2005

The mechanism behind the biphasic pulsatile drug release from physically mixed poly(dl-lactic(-co-glycolic) acid)-based compacts

artículo científico publicado en 2018

The mode of drug particle detachment from carrier crystals in an air classifier-based inhaler.

artículo científico publicado en 2004

The pharmacokinetics of beta-cyclodextrin and hydroxypropyl-beta-cyclodextrin in the rat

artículo científico publicado en 1990

The rate of drug particle detachment from carrier crystals in an air classifier-based inhaler.

artículo científico publicado en 2004

The relation between granule size, granule stickiness, and torque in the high-shear granulation process.

artículo científico publicado en 2005

The role of particle engineering in relation to formulation and de-agglomeration principle in the development of a dry powder formulation for inhalation of cetrorelix.

artículo científico publicado en 2004

The use of Stokes deformation number as a predictive tool for material exchange behaviour of granules in the 'equilibrium phase' in high shear granulation.

artículo científico publicado en 2006

Thermal Gradient Mid- and Far-Infrared Spectroscopy as Tools for Characterization of Protein Carbohydrate Lyophilizates

artículo científico publicado en 2017

Tolerability and Pharmacokinetic Evaluation of Inhaled Dry Powder Tobramycin Free Base in Non-Cystic Fibrosis Bronchiectasis Patients

artículo científico publicado en 2016

Towards an oral influenza vaccine: comparison between intragastric and intracolonic delivery of influenza subunit vaccine in a murine model

artículo científico publicado en 2007

Towards the Oral Treatment of Ileo-Colonic Inflammatory Bowel Disease with Infliximab Tablets: Development and Validation of the Production Process

scientific article published on 23 August 2019

Trends in the technology-driven development of new inhalation devices

artículo científico publicado en 2005

Unraveling protein stabilization mechanisms: vitrification and water replacement in a glass transition temperature controlled system.

artículo científico publicado en 2013

Using the internal stress concept to assess the importance of moisture sorption-induced swelling on the moisture transport through the glassy HPMC films

artículo científico publicado en 2008

pH-dependent ileocolonic drug delivery, part I: in vitro and clinical evaluation of novel systems

scientific article published on 15 June 2020

pH-dependent ileocolonic drug delivery, part II: preclinical evaluation of novel drugs and novel excipients

scientific article published on 17 June 2020

siRNA-Mediated RNA Interference in Precision-Cut Tissue Slices Prepared from Mouse Lung and Kidney

artículo científico publicado en 2017

siRNA-mediated protein knockdown in precision-cut lung slices

artículo científico publicado en 2018

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